Standard name
Human Ortholog
Description UDP-glucose:sterol glucosyltransferase; conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.96 0.98 0.95 0.92 0.89 0.86 0.85 0.79 – 0.71 0.69 0.98 0.99 1.0 0.97 0.94 0.94 0.96 0.83 0.87 0.93 0.89 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.05 0 0.17 0.08 0.26 0.27 0.31 0.42 – 0.49 0.57 0 0 0 0 0 0 0 0 0.05 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0.12 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 1 0 1 – 0 1 0 0 0 0 1 2 0 0 2 1 3 3
Bud 0 0 0 2 6 10 6 5 5 – 6 10 1 1 3 1 0 2 1 0 2 3 3 7
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 1 0 1 2
Bud Site 0 0 0 0 0 1 0 0 0 – 0 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 6 1 2 2 2 6 3 6 11 – 7 9 1 8 11 13 7 14 0 0 0 0 4 4
Cytoplasm 385 174 305 271 365 336 468 446 267 – 221 266 260 396 420 418 265 427 379 163 274 174 286 291
Endoplasmic Reticulum 4 2 0 0 1 3 3 0 4 – 1 1 1 0 0 15 6 17 2 0 1 0 2 5
Endosome 0 0 1 1 12 4 3 3 3 – 0 2 1 1 0 1 1 1 2 2 3 0 1 4
Golgi 0 0 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 2 0 0 0 0 1 1
Mitochondria 1 9 11 47 33 97 146 161 142 – 154 219 3 0 14 8 4 7 3 1 15 1 4 2
Nucleus 1 1 0 0 1 1 2 2 2 – 1 2 0 0 0 1 2 3 0 1 0 1 1 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 – 1 2 0 0 1 0 0 0 0 1 0 0 0 0
Nucleolus 0 0 0 0 1 1 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 1 1 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 8 5 3 2 1 – 0 1 0 0 0 0 1 2 0 0 3 0 1 2
Vac/Vac Membrane 1 0 0 0 0 0 5 3 1 – 4 7 0 3 1 6 12 23 0 24 1 0 1 1
Unique Cell Count 392 181 312 284 398 379 543 525 340 312 384 265 399 421 429 282 454 395 196 314 187 321 334
Labelled Cell Count 398 187 319 324 431 465 642 629 438 395 522 267 409 451 463 300 500 395 196 314 187 321 334


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 4.7 4.0 3.8 4.2 3.9 3.9 4.3 3.8 – 3.8 3.7 5.5 5.8 5.0 7.5 8.3 8.5 5.4 5.0 5.8
Std Deviation (1e-4) 0.7 0.8 0.8 1.2 1.3 0.9 0.9 1.3 1.1 – 1.2 1.1 1.1 1.7 1.3 1.5 1.6 2.3 1.6 1.4 1.2
Intensity Change (Log2) – – – -0.06 0.08 -0.03 -0.04 0.09 -0.08 – -0.08 -0.1 0.45 0.54 0.32 0.92 1.06 1.09 0.44 0.31 0.54


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – 0 0
Bud Neck – – – – – – – – – – – – – 0 0
Bud Site – – – – – – – – – – – – – 0 0
Cell Periphery – – – – – – – – – – – – – 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – 0 0
Endosome – – – – – – – – – – – – – 0 0
Golgi – – – – – – – – – – – – – 0 0
Mitochondria – – – – – – – – – – – – – 0 0
Nuclear Periphery – – – – – – – – – – – – – 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – 0 0
Peroxisomes – – – – – – – – – – – – – 0 0
SpindlePole – – – – – – – – – – – – – 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – 0 0
Cytoplasm – – – – – – – – – – – – – 0 0
Nucleus – – – – – – – – – – – – – 0 0
Vacuole – – – – – – – – – – – – – 3.7 4.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0732 4.1147 3.7611 3.3906 4.0011 3.9396 2.4804 2.6786 2.4053 2.9397 2.0241 2.6737 0.8622 1.3866 1.5272 1.5285 0.8481 1.7245
Actin 0.0005 0.0004 0.0006 0.0018 0.0002 0.0005 0.0336 0.0013 0.0119 0.0085 0.0377 0.0024 0.0005 0.0002 0.0324 0.0004 0.0002 0.0063
Bud 0 0.0001 0.0003 0.0003 0.0001 0 0.0013 0.0002 0.0006 0.001 0.0008 0.0001 0.0002 0.0001 0.002 0.0003 0 0.0023
Bud Neck 0.0001 0.0003 0.0009 0.0007 0.0002 0.0092 0.0038 0.0001 0.0002 0.0026 0.0008 0.0007 0.0001 0.0001 0.0054 0.0003 0.0002 0.0003
Bud Periphery 0 0.0001 0.0015 0.0005 0 0.0001 0.0017 0.0001 0.0007 0.0009 0.0012 0.0001 0.0002 0 0.0025 0.0003 0 0.0075
Bud Site 0.0001 0.0069 0.0012 0.0009 0.0001 0.0001 0.0105 0.0007 0.0011 0.0165 0.0028 0.0002 0.0001 0.0003 0.0089 0.0001 0 0.0001
Cell Periphery 0.0006 0.0016 0.0059 0.0013 0.0004 0.0007 0.0003 0.0001 0.0001 0.0003 0.0001 0 0.0001 0.0002 0.0014 0.0001 0 0.0001
Cytoplasm 0.6245 0.8009 0.8083 0.8256 0.8116 0.8751 0.4737 0.7145 0.6577 0.6481 0.531 0.7618 0.403 0.4716 0.4938 0.3496 0.5484 0.4763
Cytoplasmic Foci 0.0027 0.0091 0.0043 0.0073 0.0033 0.003 0.0423 0.0096 0.0088 0.0308 0.0437 0.0136 0.0054 0.0023 0.0126 0.0031 0.0047 0.0028
Eisosomes 0.0002 0.0001 0.0001 0.0003 0 0 0.0003 0 0.0001 0 0.0002 0 0.0001 0.0001 0.0004 0 0 0.0001
Endoplasmic Reticulum 0.0037 0.0027 0.0046 0.004 0.0022 0.0031 0.006 0.0011 0.0022 0.0018 0.002 0.0013 0.0019 0.0014 0.0061 0.0007 0.0006 0.001
Endosome 0.0009 0.0019 0.002 0.0026 0.0022 0.0006 0.0517 0.0013 0.0041 0.0153 0.0577 0.005 0.0007 0.0005 0.0056 0.0004 0.0007 0.0011
Golgi 0.0003 0.0001 0.0003 0.0003 0.0001 0.0001 0.0172 0.0019 0.0014 0.0327 0.0168 0.004 0.0001 0.0001 0.0062 0 0 0.0004
Lipid Particles 0.0005 0.0002 0.0005 0.0005 0 0.0001 0.0289 0.0005 0.0011 0.0414 0.0193 0.0011 0.0003 0.0001 0.0018 0 0 0.0001
Mitochondria 0.0002 0.0001 0.0004 0.0003 0.0001 0.0001 0.018 0.0014 0.0033 0.0055 0.0296 0.0038 0.0001 0.0001 0.0096 0.0001 0.0001 0.0004
None 0.3641 0.1714 0.1646 0.1503 0.1769 0.1052 0.2336 0.259 0.2958 0.1628 0.2367 0.1945 0.5843 0.5214 0.4046 0.6432 0.4432 0.5001
Nuclear Periphery 0.0003 0.0005 0.0006 0.0005 0.0004 0.0002 0.0112 0.0003 0.0011 0.0012 0.0011 0.0003 0.0003 0.0004 0.0009 0.0002 0.0002 0.0002
Nucleolus 0.0001 0.0001 0.0001 0.0001 0 0 0.0041 0 0.0001 0.0033 0.0003 0 0 0 0.0002 0 0 0
Nucleus 0.0005 0.0014 0.0011 0.001 0.0009 0.0007 0.0091 0.0007 0.0012 0.0026 0.0014 0.0009 0.0007 0.0006 0.0012 0.0005 0.0009 0.0003
Peroxisomes 0.0001 0.0001 0.0001 0.0001 0 0 0.0242 0.0058 0.0054 0.0134 0.0089 0.0091 0.0002 0 0.0019 0 0 0.0001
Punctate Nuclear 0.0002 0.0008 0.0003 0.0003 0.0001 0.0002 0.0201 0.0008 0.0023 0.0064 0.0034 0.0005 0.0002 0.0002 0.0011 0.0002 0.0003 0.0001
Vacuole 0.0005 0.001 0.0022 0.0013 0.0009 0.0006 0.0047 0.0006 0.0008 0.0044 0.0034 0.0003 0.0011 0.0004 0.0011 0.0003 0.0002 0.0004
Vacuole Periphery 0 0.0001 0.0001 0.0001 0.0001 0 0.0038 0.0001 0.0002 0.0004 0.0012 0.0001 0.0001 0 0.0003 0 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.5892 13.4369 16.2788 19.1951 11.534 11.0371 18.7154 26.7604 25.9837 14.7431
Translational Efficiency 0.5317 0.4403 0.4702 0.3898 0.3349 0.485 0.43 0.2938 0.3222 0.4113

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1304 81 1419 1011 484 2051 353 140 1788 2132 1772 1151

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 587.93 821.43 1108.65 940.02 621.82 749.67 893.15 939.64 597.10 752.40 1065.72 939.97
Standard Deviation 77.26 85.76 135.07 107.35 110.65 96.27 119.50 121.17 88.85 96.87 157.68 109.13
Intensity Change Log 2 — 0.482493 0.915088 0.677047 — 0.269759 0.522405 0.595611 — 0.377066 0.726589 0.635763

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000061 0.000251 0.000322 0.001801 0.000112 0.000275 0.000063 0.001591 0.000074 0.000274 0.000271 0.001775
Bud Neck 0.010193 0.012217 0.004935 0.004681 0.011936 0.024264 0.002983 0.002686 0.010665 0.023806 0.004546 0.004439
Bud Site 0.005238 0.009859 0.017295 0.046893 0.003757 0.015598 0.001333 0.010703 0.004837 0.015380 0.014115 0.042491
Cell Periphery 0.000105 0.000111 0.000142 0.000244 0.000183 0.000094 0.000604 0.000188 0.000126 0.000095 0.000234 0.000237
Cytoplasm 0.588109* 0.452996* 0.481036* 0.523880* 0.500310* 0.560583* 0.443306* 0.425535* 0.564342* 0.556495* 0.473520* 0.511918*
Cytoplasmic Foci 0.147522 0.226230* 0.006973 0.027411 0.212524* 0.170742 0.057022 0.055233 0.165117 0.172850 0.016943 0.030795
Eisosomes 0.000100 0.000087 0.000021 0.000052 0.000281 0.000076 0.000233 0.000074 0.000149 0.000077 0.000064 0.000054
Endoplasmic Reticulum 0.000492 0.001026 0.002620 0.001772 0.000948 0.000617 0.000789 0.002093 0.000616 0.000633 0.002256 0.001811
Endosome 0.014905 0.042765 0.001572 0.010301 0.011380 0.013764 0.003103 0.023213 0.013951 0.014866 0.001877 0.011872
Golgi 0.000854 0.002698 0.000085 0.006073 0.001367 0.004169 0.000075 0.004156 0.000993 0.004113 0.000083 0.005840
Lipid Particles 0.004475 0.006183 0.000827 0.001419 0.008788 0.002900 0.002167 0.001708 0.005643 0.003024 0.001094 0.001454
Mitochondria 0.002655 0.000833 0.000551 0.005901 0.003802 0.007341 0.000166 0.003194 0.002966 0.007094 0.000474 0.005572
Mitotic Spindle 0.000386 0.010227 0.011188 0.067423 0.000374 0.008634 0.000231 0.032095 0.000383 0.008694 0.009005 0.063126
None 0.010514 0.001191 0.005930 0.003523 0.013079 0.001458 0.016333 0.001465 0.011208 0.001448 0.008002 0.003273
Nuclear Periphery 0.000315 0.000315 0.001537 0.000711 0.000547 0.000301 0.000583 0.000739 0.000378 0.000302 0.001347 0.000714
Nuclear Periphery Foci 0.000695 0.000958 0.002214 0.002269 0.000625 0.000329 0.000639 0.002308 0.000676 0.000353 0.001900 0.002274
Nucleolus 0.001770 0.000763 0.000200 0.000167 0.001519 0.001041 0.001132 0.000112 0.001702 0.001030 0.000385 0.000160
Nucleus 0.123674 0.096343 0.393324* 0.074836 0.168219* 0.099032 0.379027* 0.092126 0.135732* 0.098929 0.390476* 0.076939
Peroxisomes 0.001787 0.005078 0.000092 0.001357 0.003406 0.006403 0.000304 0.003819 0.002225 0.006353 0.000134 0.001657
Vacuole 0.085091 0.127265 0.068992 0.214886* 0.056087 0.080271 0.089804 0.327460* 0.077240 0.082057 0.073138 0.228579*
Vacuole Periphery 0.001059 0.002605 0.000146 0.004399 0.000757 0.002107 0.000105 0.009502 0.000977 0.002126 0.000138 0.005019

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.17 -16.16 -2.59 -1.75 -0.78 -3.38 -1.87 -2.08 -1.42 -1.89 -4.47 -15.78 -2.82 -1.86 -1.16
Bud Neck -0.26 3.41 6.46 1.25 3.41 -5.45 4.83 5.35 15.05 1.41 -8.09 5.07 7.99 14.03 3.34
Bud Site -1.80 -3.52 -5.39 -2.47 -2.12 -8.98 3.12 -3.26 3.71 -4.45 -7.79 -3.43 -5.86 -0.61 -2.83
Cell Periphery -0.46 -5.89 -1.49 -0.95 1.63 4.53 -2.34 1.19 -2.17 2.62 2.68 -3.80 -0.40 -2.11 3.09
Cytoplasm 4.33 22.33 17.63 2.34 -1.92 -4.43 5.66 5.30 8.32 1.20 0.87 21.88 17.39 16.74 -1.23
Cytoplasmic Foci -3.48 33.20 29.08 9.69 -11.74 4.27 17.25 18.03 22.44 2.43 -1.17 37.10 34.74 35.00 -5.29
Eisosomes 1.03 11.23 7.47 2.98 -7.69 2.13 0.90 2.22 1.27 6.58 2.72 3.16 3.56 5.22 2.12
Endoplasmic Reticulum -2.43 -18.08 -12.10 -4.24 8.98 2.09 -3.76 -3.89 -4.86 -0.79 -0.19 -17.78 -11.86 -9.88 7.92
Endosome -2.59 10.26 8.26 3.67 -3.46 -1.31 5.39 1.50 2.26 -0.87 -0.57 11.69 8.64 10.17 -2.97
Golgi -1.49 9.18 -0.90 1.04 -2.40 -4.45 4.48 0.63 3.72 -1.30 -5.82 9.04 -0.57 4.10 -2.60
Lipid Particles -0.82 9.86 7.94 2.23 -3.88 4.32 4.72 5.28 3.78 2.94 5.07 9.42 8.68 4.32 -2.15
Mitochondria 2.25 2.36 1.23 -1.18 -1.32 -1.50 1.71 1.39 5.99 -1.37 -3.30 2.83 1.67 5.35 -1.57
Mitotic Spindle -1.11 -7.13 -7.73 -2.02 -3.15 -5.74 -0.28 -1.55 -0.16 -1.54 -5.85 -7.12 -7.88 -5.01 -3.76
None 5.68 3.17 4.24 -5.37 4.51 3.75 0.18 3.56 -1.38 2.63 6.70 2.74 5.33 -5.42 3.98
Nuclear Periphery 0.04 -28.41 -18.24 -14.58 9.03 2.74 -5.10 -4.06 -6.91 0.32 1.50 -27.26 -17.68 -17.82 7.88
Nuclear Periphery Foci -1.13 -8.30 -8.69 -4.96 1.55 3.35 -3.32 -5.96 -6.93 -3.93 4.33 -8.79 -10.12 -12.20 0.41
Nucleolus 4.17 6.40 7.73 3.68 1.54 1.14 1.78 4.72 2.92 2.79 1.88 6.60 8.96 2.70 2.77
Nucleus 1.62 -38.37 -0.38 -1.77 38.27 7.33 -10.74 3.42 -2.10 13.00 7.10 -38.22 1.85 -5.04 39.75
Peroxisomes -2.50 9.85 6.76 3.64 -4.07 -3.85 7.31 3.52 6.40 -1.14 -6.32 12.26 8.46 9.27 -3.73
Vacuole -2.58 -6.54 -30.68 -14.47 -25.38 -5.07 -9.20 -14.77 -13.90 -8.95 -1.57 -10.68 -34.62 -34.21 -26.27
Vacuole Periphery -2.04 5.85 0.16 1.87 -1.90 -3.43 5.30 -0.67 0.02 -1.00 -3.03 7.08 -0.30 1.74 -2.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description UDP-glucose:sterol glucosyltransferase; conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy
Localization
Cell Percentages cytoplasm (67%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Atg26

Atg26


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Atg26-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available