Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.6 0.42 0.42 0.54 0.58 0.4 0.46 0.42 0.34 0.32 0.28 0.4 0.5 0.4 0.39 0.41 0.36 0.28 0.22 0.2 0.18 0.15 0.13 0.21
Bud 0.13 0.19 0.17 0.14 0.19 0.15 0.18 0.07 0.12 0.1 0.13 0.09 0.1 0.06 0.11 0.06 0.16 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.15 0.07 0 0 0
Bud Site 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.51 0.34 0.57 0.5 0.35 0.37 0.37 0.34 0.25 0.35 0.23 0.33 0.64 0.65 0.68 0.65 0.72 0.56 0.54 0.34 0.6 0.7 0.74 0.67
Cytoplasm 0.16 0.25 0.18 0.19 0.2 0.18 0.19 0.2 0.2 0.15 0.11 0.23 0.19 0.18 0.14 0.18 0.12 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.05 0 0 0.05 0 0.07 0.09 0.05 0 0.08 0.05 0 0 0.06 0.06 0 0.06 0 0.07 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0 0.06 0 0 0 0 0 0
Mitochondria 0.13 0.14 0 0.13 0.05 0.33 0.35 0.22 0.6 0.68 0.67 0.53 0.07 0.07 0.07 0 0.16 0.22 0 0.05 0.05 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0.07 0 0 0 0 0 0 0.07 0.16 0.05 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.12 0.09 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 123 48 106 117 138 113 142 98 56 56 46 72 97 79 83 7 9 5 53 34 62 18 24 46
Bud 27 22 44 31 44 43 56 17 19 17 21 16 19 11 23 1 4 0 9 2 2 0 0 0
Bud Neck 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 22 25 23 4 4 6
Bud Site 11 2 2 3 4 2 3 4 0 3 0 1 3 3 1 0 0 0 – – – – – –
Cell Periphery 104 39 145 109 82 104 113 80 41 62 38 60 125 130 144 11 18 10 131 56 203 89 133 150
Cytoplasm 32 29 45 41 48 51 59 47 33 26 18 42 37 36 30 3 3 3 4 5 3 2 5 4
Endoplasmic Reticulum 8 6 3 1 11 12 21 21 8 4 13 10 1 1 12 1 0 1 7 11 8 0 4 3
Endosome 0 0 0 0 0 4 0 0 0 0 0 1 0 5 0 0 0 0 2 4 4 0 1 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 1 1 2 0 0 0 1
Mitochondria 27 16 6 28 12 93 109 51 99 119 109 96 14 14 15 0 4 4 1 8 17 3 3 2
Nucleus 2 2 6 0 0 0 2 4 2 2 2 1 1 0 0 0 0 0 0 1 0 0 0 0
Nuclear Periphery 0 0 1 0 0 0 0 0 0 1 2 0 0 0 1 0 0 0 1 0 2 0 0 0
Nucleolus 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Peroxisomes 1 1 0 1 1 21 1 5 1 1 0 3 13 31 11 0 0 0 0 0 0 1 0 1
SpindlePole 5 0 11 25 21 6 3 12 0 1 0 0 2 8 1 0 0 0 0 0 0 0 0 1
Vac/Vac Membrane 1 1 1 2 0 11 0 15 0 5 0 4 1 3 0 0 0 1 3 8 7 1 0 1
Unique Cell Count 205 114 254 217 236 280 308 233 165 175 162 182 195 199 213 17 25 18 242 168 340 127 181 225
Labelled Cell Count 341 167 371 358 361 460 510 355 259 297 249 306 314 321 321 25 38 25 242 168 340 127 181 225


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.1 6.5 6.8 6.1 6.9 6.0 6.1 6.9 5.4 5.5 5.3 6.0 7.1 7.3 7.3 13.0 12.2 13.2 6.5 6.7 7.2
Std Deviation (1e-4) 1.3 1.1 0.9 0.8 0.9 1.1 0.9 1.3 0.7 0.8 0.9 0.9 2.2 1.6 1.4 3.6 2.0 3.4 1.9 1.5 1.5
Intensity Change (Log2) – – – -0.17 0.01 -0.19 -0.15 0.01 -0.33 -0.3 -0.36 -0.19 0.06 0.1 0.1 0.93 0.84 0.95 -0.07 -0.02 0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 2.6 3.7 -0.3 1.0 0.1 -1.6 -2.0 -2.8 -0.5 1.7 -0.4 -0.6 0 -0.6 -1.2
Bud -0.9 0.4 -0.6 0.3 -3.3 -1.6 -2.2 -1.2 -2.6 -2.3 -3.8 -2.0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.5 -5.0 -4.6 -4.8 -5.0 -6.5 -4.4 -6.7 -5.0 1.5 1.8 2.3 0.6 1.4 -0.1
Cytoplasm 0.3 0.7 0.1 0.4 0.7 0.6 -0.8 -1.8 1.4 0.3 0.1 -1.1 0 0 0
Endoplasmic Reticulum 0 2.3 2.2 3.3 4.0 0 0 3.5 2.6 0 0 2.7 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.4 1.6 9.2 9.7 6.7 13.3 14.7 14.4 12.3 2.5 2.4 2.4 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 4.5 0 0 0 0 0 0 4.2 6.5 3.7 0 0 0
SpindlePole 2.9 2.0 -1.4 -2.5 0.4 0 0 0 0 -2.1 -0.2 -2.6 0 0 0
Vacuole 0 0 2.8 0 3.7 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.873 2.8318 3.2151 2.6253 2.6256 3.2159 5.182 3.9954 3.9374 3.7819 4.0197 4.2342 4.3173 2.8388 3.2491 3.7214 2.7519 3.5042
Actin 0.0453 0.0346 0.0373 0.0427 0.0641 0.0271 0.0239 0.0023 0.0496 0.0294 0.0237 0.0095 0.05 0.0075 0.0259 0.0399 0.0463 0.0143
Bud 0.0048 0.0125 0.0431 0.0478 0.0319 0.0056 0.003 0.0034 0.0249 0.0127 0.0171 0.0018 0.0025 0.0056 0.0338 0.0184 0.0213 0.0026
Bud Neck 0.0119 0.0093 0.0265 0.008 0.0132 0.1098 0.0061 0.0067 0.0183 0.0091 0.039 0.0507 0.027 0.0109 0.0227 0.0101 0.0024 0.0639
Bud Periphery 0.0435 0.0615 0.3139 0.6195 0.3704 0.1087 0.025 0.0154 0.2088 0.2605 0.3131 0.0441 0.017 0.0354 0.3216 0.3353 0.3836 0.0506
Bud Site 0.0456 0.4218 0.1711 0.0205 0.0458 0.0123 0.0211 0.3346 0.1212 0.0115 0.0109 0.0033 0.0567 0.4266 0.1374 0.0335 0.0062 0.0044
Cell Periphery 0.6272 0.3228 0.2978 0.13 0.3293 0.6363 0.7627 0.5348 0.4907 0.4974 0.5513 0.8198 0.6236 0.3846 0.3434 0.3656 0.3126 0.745
Cytoplasm 0.0659 0.1033 0.0522 0.0352 0.0132 0.0577 0.0539 0.0914 0.033 0.0333 0.0351 0.0402 0.0645 0.1171 0.049 0.0687 0.0567 0.0664
Cytoplasmic Foci 0.0148 0.0018 0.004 0.0064 0.0283 0.002 0.0084 0.0002 0.0046 0.0046 0.0002 0.0003 0.0253 0.001 0.0045 0.0008 0.0311 0.0015
Eisosomes 0.0185 0.0097 0.0052 0.0048 0.0022 0.0154 0.0324 0.0056 0.0077 0.017 0.0028 0.0154 0.0041 0.0022 0.0053 0.0077 0.001 0.0014
Endoplasmic Reticulum 0.0137 0.0041 0.0036 0.0015 0.0032 0.0052 0.0086 0.0014 0.0061 0.0175 0.0025 0.0043 0.0068 0.0021 0.0092 0.0037 0.0018 0.0124
Endosome 0.0244 0.0006 0.0067 0.0033 0.0317 0.0034 0.0096 0 0.0057 0.009 0.0001 0.001 0.0376 0.0002 0.0164 0.002 0.0458 0.006
Golgi 0.0137 0.003 0.0118 0.0086 0.0174 0.0017 0.0048 0.0001 0.0041 0.0129 0.0003 0.0016 0.0125 0.0005 0.0046 0.0081 0.0228 0.0053
Lipid Particles 0.0121 0.0033 0.0023 0.002 0.0096 0.001 0.0052 0.0002 0.0024 0.01 0.0002 0.0005 0.0176 0.0007 0.0014 0.0226 0.0023 0.0007
Mitochondria 0.0131 0.003 0.0074 0.0576 0.0055 0.002 0.0061 0 0.009 0.0503 0.0002 0.0014 0.0118 0.0001 0.0062 0.0237 0.012 0.0055
None 0.0034 0.003 0.0089 0.0009 0.0016 0.0024 0.0025 0.0004 0.0014 0.0063 0.0004 0.0004 0.0142 0.0011 0.002 0.0461 0.0005 0.0014
Nuclear Periphery 0.0092 0.0005 0.0004 0.0003 0.007 0.0005 0.0017 0.0003 0.0017 0.0038 0.0003 0.0006 0.0013 0.0004 0.0027 0.0009 0.0003 0.0095
Nucleolus 0.001 0.0003 0.0004 0.0002 0.0013 0.0005 0.001 0.0001 0.0004 0.0004 0.0001 0.0001 0.0007 0.0002 0.0002 0.0004 0.0001 0.0003
Nucleus 0.0033 0.0006 0.0007 0.0004 0.0032 0.001 0.0012 0.0004 0.0013 0.0018 0.0002 0.0015 0.0012 0.0005 0.0012 0.0029 0.0003 0.002
Peroxisomes 0.0126 0.0006 0.0012 0.0078 0.0087 0.0009 0.0074 0 0.0033 0.0039 0 0.0001 0.0133 0.0001 0.0002 0.0018 0.0469 0.0002
Punctate Nuclear 0.0056 0.0001 0.0001 0.0002 0.0041 0.0002 0.0073 0 0.0018 0.0015 0 0.0001 0.0023 0.0001 0.0004 0.0004 0.002 0.0002
Vacuole 0.0085 0.0034 0.0051 0.0019 0.0071 0.006 0.0074 0.0026 0.0038 0.0062 0.0026 0.0031 0.0093 0.0031 0.0101 0.0064 0.0027 0.0054
Vacuole Periphery 0.002 0.0002 0.0004 0.0004 0.0013 0.0004 0.0006 0 0.0003 0.0008 0.0001 0.0001 0.0007 0.0001 0.0018 0.001 0.0012 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.6313 13.9816 13.0523 13.5076 17.0077 12.102 20.2931 19.0827 17.9137 17.5961
Translational Efficiency 0.9789 0.8968 0.762 0.7278 0.6259 1.1962 0.7519 0.7685 0.8728 0.9125

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
382 955 1134 1185 1482 1835 234 46 1864 2790 1368 1231

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 775.77 940.85 1201.67 1046.23 792.07 838.81 1216.46 1413.29 788.73 873.74 1204.20 1059.95
Standard Deviation 99.69 136.06 162.10 128.88 104.16 121.43 165.19 209.68 103.47 135.57 162.73 149.93
Intensity Change Log 2 — 0.278336 0.631340 0.431499 — 0.082716 0.618989 0.835358 — 0.182823 0.625113 0.649598

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.064032 0.102669* 0.083281 0.057366 0.069963 0.076271 0.091574 0.145098* 0.068748 0.085307 0.084700 0.060645
Bud Neck 0.030543 0.051663 0.074287 0.053521 0.043119 0.057439 0.086075 0.071874 0.040542 0.055462 0.076304 0.054207
Bud Site 0.039528 0.137093* 0.203109* 0.177207* 0.057538 0.088301 0.186728* 0.194477* 0.053847 0.105002* 0.200307* 0.177852*
Cell Periphery 0.666167* 0.519432* 0.453101* 0.614307* 0.445877* 0.412447* 0.418939* 0.255318* 0.491022* 0.449068* 0.447257* 0.600892*
Cytoplasm 0.051486 0.089682 0.053160 0.057885 0.158977* 0.163410* 0.028108 0.234199* 0.136948* 0.138173* 0.048875 0.064474
Cytoplasmic Foci 0.004114 0.004348 0.002361 0.001592 0.005708 0.006565 0.005605 0.001837 0.005381 0.005806 0.002916 0.001601
Eisosomes 0.070852 0.055465 0.032169 0.022054 0.129465* 0.103237* 0.059200 0.052247 0.117453* 0.086885 0.036793 0.023183
Endoplasmic Reticulum 0.005174 0.006237 0.045473 0.003944 0.007694 0.008659 0.039050 0.003702 0.007178 0.007830 0.044374 0.003935
Endosome 0.003236 0.001387 0.001872 0.000589 0.002100 0.003086 0.001867 0.000239 0.002333 0.002505 0.001871 0.000576
Golgi 0.002301 0.002575 0.001944 0.000610 0.006396 0.006194 0.001405 0.000150 0.005557 0.004955 0.001852 0.000593
Lipid Particles 0.002492 0.001919 0.007429 0.000970 0.005517 0.005686 0.003649 0.000482 0.004897 0.004397 0.006782 0.000952
Mitochondria 0.015261 0.008174 0.000580 0.000487 0.006127 0.009521 0.000154 0.003623 0.007999 0.009060 0.000507 0.000605
Mitotic Spindle 0.000273 0.000794 0.000362 0.000195 0.000121 0.000155 0.000174 0.000034 0.000152 0.000374 0.000330 0.000189
None 0.000102 0.000073 0.000080 0.000042 0.000173 0.000168 0.000024 0.000073 0.000158 0.000135 0.000070 0.000043
Nuclear Periphery 0.000044 0.000058 0.000289 0.000094 0.000090 0.000076 0.000134 0.000035 0.000081 0.000070 0.000263 0.000091
Nuclear Periphery Foci 0.000106 0.000139 0.001117 0.000212 0.000153 0.000151 0.002335 0.000033 0.000143 0.000147 0.001325 0.000205
Nucleolus 0.000028 0.000030 0.000022 0.000013 0.000028 0.000037 0.000013 0.000032 0.000028 0.000034 0.000021 0.000014
Nucleus 0.000923 0.001969 0.006857 0.000977 0.003608 0.002276 0.006163 0.014323 0.003058 0.002171 0.006738 0.001476
Peroxisomes 0.039988 0.010187 0.001381 0.000622 0.053583 0.052239 0.000431 0.001418 0.050797 0.037845 0.001218 0.000651
Vacuole 0.001916 0.005701 0.030826 0.007202 0.003531 0.003366 0.068319 0.020740 0.003200 0.004165 0.037239 0.007708
Vacuole Periphery 0.001434 0.000405 0.000300 0.000109 0.000232 0.000716 0.000051 0.000065 0.000478 0.000609 0.000258 0.000108

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.04 -2.20 0.78 6.74 4.77 -1.29 -2.13 -2.43 -2.23 -1.71 -3.78 -3.17 1.66 5.30 4.59
Bud Neck -4.06 -8.57 -4.66 -0.42 4.73 -4.06 -5.15 -1.80 -0.88 0.77 -5.12 -9.89 -3.86 0.36 5.25
Bud Site -11.36 -19.31 -16.18 -4.20 2.66 -5.96 -8.61 -3.85 -2.98 -0.21 -11.28 -21.83 -17.23 -9.75 2.42
Cell Periphery 7.29 11.44 2.72 -6.52 -12.87 2.99 1.74 4.15 3.45 3.21 4.22 4.38 -8.96 -13.44 -12.88
Cytoplasm -5.89 -0.50 -1.05 6.29 -0.78 -0.70 21.82 -2.11 -1.99 -5.67 -0.25 18.14 13.62 15.72 -3.35
Cytoplasmic Foci -0.26 1.35 1.78 2.33 0.93 -0.99 -0.47 2.37 2.89 2.10 -0.63 3.31 4.57 5.10 1.85
Eisosomes 2.08 5.63 7.08 9.62 4.69 4.93 10.11 4.42 2.95 0.34 6.98 20.49 23.99 21.75 5.92
Endoplasmic Reticulum -0.75 -13.39 1.06 2.16 14.51 -0.75 -6.72 1.49 1.81 6.72 -0.65 -14.54 3.93 4.51 16.10
Endosome 2.61 1.96 3.81 3.19 6.18 -1.79 0.11 5.95 5.99 5.16 -0.42 1.38 5.62 5.56 6.74
Golgi -0.39 0.74 3.11 3.52 4.07 0.19 7.17 9.18 7.21 7.22 0.76 6.52 8.18 6.91 4.14
Lipid Particles 0.52 -4.95 1.93 1.15 9.10 -0.17 1.74 7.11 7.24 5.20 0.65 -2.42 6.46 5.96 9.63
Mitochondria 1.60 3.59 3.61 4.47 1.11 -2.99 10.32 2.05 4.05 -3.16 -0.82 7.80 7.69 9.69 -1.01
Mitotic Spindle -0.89 -0.52 0.44 1.06 6.94 -1.53 -3.38 10.33 5.40 9.13 -1.14 -4.58 -1.11 0.94 6.65
None 1.25 0.81 2.89 3.32 4.02 0.23 7.19 3.76 4.22 -2.68 1.20 4.58 6.83 9.02 3.46
Nuclear Periphery -2.30 -13.49 -4.16 -2.83 9.22 2.17 -3.72 4.72 3.79 6.67 2.04 -11.64 -0.90 -1.89 9.23
Nuclear Periphery Foci -1.13 -13.75 -3.50 -3.55 12.86 0.05 -5.08 5.32 4.60 5.33 -0.17 -12.00 -2.72 -2.62 11.45
Nucleolus -0.09 0.56 1.42 1.56 6.53 -1.76 3.84 -0.58 0.61 -2.48 -1.15 2.30 4.95 4.29 5.38
Nucleus -2.65 -5.42 -0.24 3.98 5.50 4.24 -2.98 -1.34 -1.49 -0.98 3.36 -4.41 3.66 1.74 5.58
Peroxisomes 5.09 6.77 6.90 7.27 4.89 0.32 17.27 16.82 18.28 -2.53 3.90 18.26 18.48 19.53 4.23
Vacuole -3.73 -14.91 -5.72 -1.27 11.88 0.27 -7.31 -2.27 -2.29 4.28 -1.81 -15.10 -5.15 -4.15 12.70
Vacuole Periphery 1.50 1.68 1.97 2.09 2.03 -2.35 7.34 5.89 3.17 -0.77 -0.66 1.40 2.62 3.46 1.90
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cell periphery (63%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-3

Msc3

Msc3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Msc3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available