Standard name
Human Ortholog
Description Lipoyl ligase; involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 – 0 0 0 0 0 0 0 0 0 0 0 0 0.08 – 0.07 0 0 0 0 0 0.05
Bud 0 0 – 0 0 0 0.05 0.08 0.09 0.05 0.05 0 0 0 0 0.06 – 0.09 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.07 – 0.06 0 0 0 0 0 0
Cytoplasm 0.33 0.43 – 0.55 0.56 0.37 0.27 0.28 0.2 0.16 0.18 0.2 0.77 0.87 0.88 0.41 – 0.25 0.05 0.17 0.09 0.1 0.1 0.11
Endoplasmic Reticulum 0 0.14 – 0 0 0 0 0 0 0 0 0 0.06 0 0 0 – 0.06 0 0 0 0 0 0
Endosome 0 0 – 0 0.06 0.06 0 0 0 0 0 0 0 0.05 0.05 0.07 – 0.2 0.08 0 0.05 0.06 0.06 0.05
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria 0.68 0.76 – 0.43 0.23 0.51 0.69 0.58 0.82 0.82 0.88 0.79 0 0 0 0.15 – 0.11 0.71 0.61 0.68 0.65 0.61 0.59
Nucleus 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.06 0 0 0 0 0 0
SpindlePole 0 0 – 0.06 0.14 0.06 0.1 0.18 0.05 0.1 0 0.09 0 0 0 0.15 – 0.12 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 0 0.07 0.06 0 0 0 0 0.05 0 0 0.06 0.11 – 0.16 0.05 0.07 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 – 1 2 0 0 1 0 1 0 0 11 4 0 9 – 6 2 2 1 5 18 35
Bud 5 0 – 3 3 1 17 23 19 13 11 11 5 2 0 7 – 8 0 0 0 1 10 14
Bud Neck 0 0 – 1 8 3 5 4 1 0 1 2 9 6 3 2 – 0 1 1 0 3 11 17
Bud Site 0 0 – 0 1 0 4 1 2 5 2 1 0 0 0 0 – 1 – – – – – –
Cell Periphery 0 0 – 0 1 3 1 2 1 1 1 1 3 11 8 8 – 5 2 0 0 1 3 10
Cytoplasm 64 9 – 47 121 79 97 78 40 41 38 57 219 543 667 47 – 22 12 12 3 32 62 76
Endoplasmic Reticulum 6 3 – 0 1 0 1 0 0 0 1 0 18 2 2 5 – 5 5 0 0 8 6 9
Endosome 0 0 – 0 13 12 1 7 1 2 0 1 10 29 39 8 – 18 20 2 2 20 37 36
Golgi 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 1 – 0 0 0 0 1 1 3
Mitochondria 133 16 – 37 51 108 246 161 165 206 187 222 9 14 5 17 – 10 175 47 28 220 365 427
Nucleus 0 0 – 0 0 3 8 13 4 6 1 8 0 0 1 0 – 3 0 0 0 0 2 2
Nuclear Periphery 1 0 – 0 0 0 0 0 0 4 1 0 0 0 1 0 – 0 0 0 1 0 3 2
Nucleolus 0 0 – 0 0 0 0 2 1 0 0 1 0 0 0 1 – 0 0 0 0 2 1 2
Peroxisomes 0 0 – 0 3 6 3 1 0 1 0 0 0 12 23 3 – 5 2 0 0 6 5 3
SpindlePole 3 0 – 5 31 13 36 49 11 25 7 26 8 13 15 17 – 11 5 1 1 10 23 31
Vac/Vac Membrane 7 0 – 1 9 15 20 5 3 8 3 15 6 22 42 13 – 14 11 5 0 11 25 33
Unique Cell Count 195 21 86 218 211 356 276 201 250 213 280 283 623 762 114 88 248 77 42 340 602 729
Labelled Cell Count 220 29 95 244 243 439 347 248 313 253 345 298 658 807 138 108 248 77 42 340 602 729


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 3.3 – 4.5 5.0 4.1 3.9 4.4 3.5 3.7 3.5 3.9 4.8 5.0 4.9 5.3 – 5.7 4.6 4.5 5.0
Std Deviation (1e-4) 0.3 0.8 – 1.3 1.9 1.5 1.8 1.7 1.2 1.4 1.4 1.6 0.8 1.0 0.9 1.3 – 1.8 1.4 1.0 1.3
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –

RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246HU80HU120HU1600246rpd3Δ_1rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.0124 -0.0743 0.0189 -0.5765 -0.6974 -0.2224 -0.1169 -0.0075 0.154 0.2378 -0.4023 -0.3495 -0.7086 -0.5531 -0.8072 -0.3674 -0.4139 -0.5033
Actin 0.0167 0.0136 0.0092 0.0055 0.0442 0.0077 0.0346 0.0148 0.0269 0.0093 0.0382 0.0024 0.0354 0.0175 0.0337 0.0026 0.0643 0.0174
Bud 0.0018 0.0116 0.0021 0.0013 0.0033 0.0011 0.0016 0.0055 0.0037 0.002 0.0028 0.0009 0.001 0.0054 0.0032 0.0036 0.0014 0.0011
Bud Neck 0.0038 0.0014 0.0018 0.0005 0.0044 0.0167 0.0041 0.0022 0.0013 0.0027 0.0019 0.0313 0.0072 0.0015 0.0015 0.0008 0.0007 0.0062
Bud Periphery 0.0038 0.0126 0.0069 0.0069 0.0105 0.0035 0.0043 0.0068 0.0093 0.0039 0.0137 0.0023 0.0021 0.0097 0.007 0.0174 0.0024 0.0026
Bud Site 0.0106 0.0449 0.0202 0.0009 0.0077 0.0016 0.0126 0.0514 0.0128 0.0103 0.0035 0.0053 0.0108 0.0475 0.0097 0.0058 0.0014 0.0044
Cell Periphery 0.0009 0.0026 0.0041 0.0004 0.0027 0.0012 0.0015 0.0037 0.0028 0.0007 0.0005 0.001 0.0021 0.0021 0.0036 0.0045 0.0004 0.0014
Cytoplasm 0.0357 0.1021 0.0756 0.0136 0.0319 0.0667 0.0386 0.1037 0.0821 0.0239 0.0468 0.0678 0.0426 0.1016 0.0666 0.0254 0.1189 0.081
Cytoplasmic Foci 0.1152 0.1096 0.0676 0.0982 0.1109 0.122 0.122 0.1429 0.1223 0.0623 0.0809 0.1067 0.0841 0.1225 0.0692 0.0475 0.0644 0.0863
Eisosomes 0.0009 0.0007 0.0008 0.0004 0.0008 0.0009 0.0012 0.0014 0.0018 0.0005 0.0003 0.0005 0.005 0.0006 0.0011 0.0007 0.0016 0.0009
Endoplasmic Reticulum 0.0043 0.0054 0.0058 0.0012 0.0032 0.0036 0.0076 0.0053 0.0038 0.0013 0.0021 0.0028 0.0184 0.0126 0.0053 0.0067 0.0123 0.0057
Endosome 0.1921 0.1452 0.0664 0.0652 0.0923 0.0882 0.1602 0.1147 0.1149 0.1383 0.1804 0.1002 0.1658 0.1527 0.1542 0.142 0.1852 0.1486
Golgi 0.0563 0.0403 0.0247 0.0331 0.0285 0.0464 0.0463 0.0574 0.0417 0.0488 0.0896 0.0391 0.0648 0.0698 0.0502 0.0463 0.1038 0.0613
Lipid Particles 0.0439 0.0273 0.05 0.0185 0.0474 0.0335 0.0865 0.0156 0.0217 0.0209 0.053 0.012 0.0349 0.0269 0.015 0.0025 0.026 0.0303
Mitochondria 0.264 0.2853 0.3984 0.4924 0.3781 0.3829 0.1831 0.2523 0.3532 0.3636 0.3429 0.4695 0.3389 0.2757 0.452 0.5654 0.2573 0.4173
None 0.1624 0.1469 0.1937 0.1649 0.0969 0.1212 0.221 0.1477 0.1501 0.1717 0.0911 0.1017 0.0985 0.0825 0.0675 0.106 0.0845 0.0807
Nuclear Periphery 0.009 0.0013 0.0058 0.0004 0.0013 0.0036 0.007 0.0027 0.0016 0.0008 0.0018 0.001 0.0141 0.0021 0.0041 0.0011 0.0215 0.001
Nucleolus 0.0054 0.002 0.0062 0.0002 0.0007 0.0066 0.0021 0.0016 0.0012 0.0012 0.0007 0.0009 0.0016 0.0012 0.001 0.0003 0.0018 0.0012
Nucleus 0.0063 0.0021 0.0051 0.0004 0.0008 0.0031 0.0029 0.0026 0.0019 0.001 0.0075 0.0025 0.004 0.0014 0.0038 0.0009 0.0144 0.0014
Peroxisomes 0.0369 0.0185 0.028 0.0872 0.114 0.0724 0.0363 0.0506 0.0287 0.1135 0.0246 0.041 0.0313 0.0428 0.032 0.0075 0.0149 0.0325
Punctate Nuclear 0.0106 0.0018 0.0089 0.0019 0.0018 0.0061 0.0095 0.0015 0.0037 0.0009 0.0064 0.0026 0.008 0.0013 0.0016 0.0006 0.0059 0.0015
Vacuole 0.0128 0.0196 0.0133 0.0031 0.0141 0.0071 0.0121 0.0124 0.011 0.0146 0.0059 0.0049 0.02 0.0175 0.0118 0.0064 0.0107 0.0108
Vacuole Periphery 0.0065 0.005 0.0055 0.004 0.0046 0.0038 0.0046 0.0031 0.0036 0.0077 0.0053 0.0035 0.0093 0.0052 0.0059 0.006 0.0064 0.0064

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.3845 6.9956 8.8989 10.0437 13.7698 11.1732 11.1151 10.5709 9.4339 11.5304
Translational Efficiency 0.826 0.8234 0.7803 0.6367 0.4786 0.8972 0.8335 0.946 0.9491 0.6673

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1555 316 238 1628 918 1866 186 824 2473 2182 424 2452

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 688.97 772.49 793.60 787.08 638.45 738.24 925.67 859.71 670.22 743.20 851.54 811.49
Standard Deviation 81.63 105.10 119.77 102.35 81.55 99.21 99.89 106.50 85.17 100.80 129.32 109.29
Intensity Change Log 2 — 0.165075 0.203971 0.192069 — 0.209516 0.535924 0.429276 — 0.186621 0.373171 0.311032

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000996 0.002349 0.011899 0.009396 0.001173 0.002507 0.005618 0.018109 0.001062 0.002484 0.009144 0.012324
Bud Neck 0.034567 0.029585 0.043905 0.039394 0.033621 0.025806 0.009847 0.030032 0.034216 0.026354 0.028964 0.036248
Bud Site 0.015699 0.037528 0.104149 0.079471 0.025286 0.029651 0.018024 0.103009 0.019258 0.030792 0.066368 0.087381
Cell Periphery 0.000273 0.000344 0.000369 0.000272 0.000528 0.000279 0.000385 0.000300 0.000368 0.000288 0.000376 0.000281
Cytoplasm 0.128762 0.031980 0.093277 0.198213 0.098391 0.038185 0.242056 0.247662 0.117488 0.037286 0.158544 0.214831
Cytoplasmic Foci 0.349567 0.188784 0.140671 0.144297 0.305232 0.178671 0.140784 0.141936 0.333109 0.180135 0.140721 0.143504
Eisosomes 0.000286 0.000240 0.000222 0.000207 0.000347 0.000216 0.000239 0.000228 0.000308 0.000220 0.000230 0.000214
Endoplasmic Reticulum 0.002517 0.001617 0.011217 0.004652 0.001501 0.000743 0.009950 0.004330 0.002140 0.000869 0.010661 0.004544
Endosome 0.069596 0.088042 0.046822 0.029546 0.072375 0.092157 0.033518 0.023119 0.070628 0.091561 0.040986 0.027386
Golgi 0.052416 0.118213 0.019152 0.016090 0.059687 0.106067 0.002060 0.011615 0.055115 0.107826 0.011654 0.014587
Lipid Particles 0.027594 0.008844 0.008102 0.005769 0.023115 0.007714 0.014921 0.003677 0.025931 0.007878 0.011093 0.005066
Mitochondria 0.162978 0.304630 0.035618 0.048129 0.237778 0.370106 0.001006 0.009394 0.190745 0.360624 0.020434 0.035112
Mitotic Spindle 0.003899 0.022547 0.066583 0.059687 0.006219 0.013505 0.007846 0.035038 0.004760 0.014815 0.040816 0.051404
None 0.001947 0.001374 0.001682 0.000707 0.001950 0.000414 0.001956 0.000926 0.001948 0.000553 0.001802 0.000780
Nuclear Periphery 0.000470 0.000312 0.001607 0.001243 0.000624 0.000142 0.002395 0.000656 0.000527 0.000166 0.001952 0.001045
Nuclear Periphery Foci 0.000338 0.000415 0.001756 0.001048 0.000383 0.000207 0.007279 0.001041 0.000355 0.000237 0.004179 0.001045
Nucleolus 0.001610 0.000688 0.003339 0.002228 0.002197 0.000833 0.002986 0.000744 0.001828 0.000812 0.003184 0.001729
Nucleus 0.031698 0.005921 0.144235 0.102702 0.021921 0.006282 0.249918 0.093714 0.028069 0.006230 0.190596 0.099682
Peroxisomes 0.046369 0.112981 0.146087 0.093989 0.063508 0.075746 0.041210 0.096849 0.052732 0.081138 0.100080 0.094950
Vacuole 0.054370 0.029458 0.113683 0.157681 0.031590 0.038919 0.205398 0.175720 0.045914 0.037548 0.153917 0.163743
Vacuole Periphery 0.014047 0.014149 0.005624 0.005278 0.012575 0.011851 0.002603 0.001902 0.013500 0.012183 0.004299 0.004144

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.83 -6.23 -7.28 -5.53 1.87 -2.76 -2.96 -6.76 -5.99 -4.32 -3.76 -6.83 -9.92 -7.95 -1.04
Bud Neck 0.98 -1.87 -0.78 -1.45 1.52 2.40 6.99 2.32 -0.01 -5.59 3.31 1.20 0.52 -3.10 -0.92
Bud Site -4.84 -8.54 -14.84 -5.31 3.34 -1.43 2.59 -9.31 -9.04 -11.21 -5.76 -7.31 -17.11 -12.35 -0.91
Cell Periphery -1.35 -2.08 1.18 2.53 3.55 2.72 1.42 2.81 0.21 3.19 1.76 -0.36 3.02 1.61 4.96
Cytoplasm 14.60 3.44 -10.31 -23.70 -10.62 10.50 -6.41 -14.32 -23.13 -2.00 19.72 -2.77 -16.88 -35.34 -7.22
Cytoplasmic Foci 13.62 20.22 32.78 5.87 0.72 15.32 14.73 21.14 9.17 0.03 26.00 25.22 38.73 11.77 0.46
Eisosomes 0.79 2.23 4.19 0.90 1.94 2.95 2.09 3.09 0.47 2.06 3.85 3.01 5.09 1.54 2.83
Endoplasmic Reticulum 1.69 -6.50 -5.57 -5.89 4.99 2.48 -8.28 -6.66 -10.10 5.63 5.58 -9.92 -8.38 -15.47 7.29
Endosome -2.53 4.23 14.53 9.27 3.13 -4.12 8.73 13.81 20.58 2.98 -5.76 8.12 19.80 22.55 3.95
Golgi -7.54 8.88 14.64 12.61 1.41 -9.62 17.34 14.28 25.88 -4.00 -13.91 16.69 20.20 28.86 -0.17
Lipid Particles 6.96 9.93 12.67 1.77 2.55 7.44 3.16 9.63 5.05 5.80 12.44 9.18 15.83 4.11 5.95
Mitochondria -7.27 14.70 18.91 14.42 -0.72 -10.91 24.88 24.14 46.82 -5.86 -19.22 26.69 29.41 45.60 -2.04
Mitotic Spindle -5.08 -5.94 -14.20 -6.46 0.71 -4.01 -0.28 -6.77 -4.89 -6.17 -7.48 -5.77 -15.60 -11.12 -1.49
None 0.49 0.52 2.70 0.62 1.25 3.54 0.56 2.26 -4.30 1.78 3.99 0.73 3.51 -1.71 1.95
Nuclear Periphery 0.94 -2.97 -8.05 -6.45 -0.31 1.70 -5.74 -1.20 -9.97 7.61 3.18 -5.92 -6.36 -12.20 2.22
Nuclear Periphery Foci -0.40 -6.23 -8.67 -3.94 2.71 2.33 -5.91 -8.70 -11.23 5.14 2.14 -7.10 -11.72 -12.13 5.54
Nucleolus 3.52 -2.35 -1.21 -4.01 1.60 3.71 -0.58 4.14 0.07 2.79 4.41 -2.27 0.66 -3.35 2.58
Nucleus 9.95 -7.91 -17.70 -23.53 2.21 6.01 -12.23 -14.52 -18.21 7.12 12.53 -13.87 -22.87 -30.31 6.40
Peroxisomes -6.50 -6.32 -6.63 3.48 4.03 -2.30 4.17 -0.94 0.92 -4.55 -7.33 -3.89 -5.66 1.59 1.42
Vacuole 5.11 -6.84 -25.92 -26.58 -5.73 -2.49 -13.76 -24.31 -23.53 0.99 3.16 -13.99 -35.48 -36.87 -2.58
Vacuole Periphery -0.03 5.37 8.82 3.56 0.73 0.52 8.32 10.23 13.97 0.69 1.20 8.88 12.50 11.13 0.62
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Lipoyl ligase; involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups
Localization
Cell Percentages mitochondrion (73%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Lip2

Lip2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Lip2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available