Standard name
Human Ortholog
Description ER-resident protein involved in peroxisomal biogenesis; ER-localized protein that associates with peroxisomes; interacts with Pex29p and reticulons Rtn1p and Yop1p to regulate peroxisome biogenesis from the ER; role in peroxisomal-destined vesicular flow from the ER; partially redundant with Pex31p; may function at a step downstream of steps mediated by Pex28p and Pex29p; PEX30 has a paralog, PEX31, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.44 0.33 0.35 0.31 0.23 0.22 0.17 0.14 0.22 0.11 0.11 0.12 0.45 0.43 0.32 0.46 0.36 – 0.38 0.35 0.4 0.46 0.45 0.36
Bud 0.13 0.06 0.09 0.14 0.12 0.1 0.1 0.1 0.1 0.09 0.08 0.09 0.05 0 0.05 0.18 0.1 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0.05 0.09 0.07 0.09 0.06 0 0 0 0 0 0 0 0.17 0.18 0.15 0.3 0.25 – 0.07 0.05 0.06 0.1 0.16 0.2
Cytoplasm 0.06 0.14 0.19 0.2 0.18 0.11 0.11 0.15 0.08 0.14 0.09 0.17 0.16 0.17 0.13 0.09 0.12 – 0 0 0 0 0 0
Endoplasmic Reticulum 0.37 0.44 0.41 0.16 0.26 0.31 0.41 0.22 0.28 0.17 0.23 0.23 0.43 0.37 0.57 0 0.12 – 0.26 0.36 0.17 0.23 0.24 0.22
Endosome 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 – 0.06 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.19 – 0 0 0 0 0 0
Mitochondria 0.57 0.51 0.44 0.44 0.4 0.56 0.58 0.58 0.71 0.78 0.66 0.68 0.08 0.07 0.06 0.12 0.16 – 0.09 0.06 0.16 0.07 0 0.07
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0.1 0.1 0.05 0 0 0 0 0 0 0 0.11 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 36 32 42 50 38 48 39 39 57 32 6 12 113 181 151 80 25 – 40 40 61 101 173 158
Bud 11 6 11 22 20 22 24 30 26 27 4 9 13 18 24 31 7 – 0 2 1 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 1 4 2 4 6 6
Bud Site 0 0 0 0 1 0 2 0 4 5 0 1 0 0 0 2 0 – – – – – – –
Cell Periphery 4 9 9 15 9 9 6 7 8 5 2 1 43 77 69 52 17 – 7 6 9 22 63 89
Cytoplasm 5 14 23 32 29 24 26 44 22 42 5 17 40 74 62 16 8 – 0 2 3 0 3 3
Endoplasmic Reticulum 30 43 50 25 43 69 93 64 74 50 12 23 108 158 268 7 8 – 27 41 25 51 91 98
Endosome 1 0 0 2 11 5 3 10 1 1 1 0 3 10 3 0 0 – 6 2 6 4 4 12
Golgi 0 0 0 0 0 0 0 3 1 2 0 0 4 9 18 28 13 – 4 2 6 6 9 19
Mitochondria 47 49 53 70 65 124 133 168 188 228 35 69 21 29 26 21 11 – 9 7 24 15 16 29
Nucleus 0 0 0 1 0 0 1 2 0 1 1 1 1 1 0 1 3 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 2 1 3 2 0 0 0 1 0 1 0 – 0 0 0 0 0 1
Nucleolus 0 0 0 0 1 1 0 2 0 1 0 0 0 0 0 0 1 – 0 0 0 1 0 0
Peroxisomes 2 1 3 16 17 10 6 3 6 5 1 0 10 45 13 3 1 – 2 0 2 3 3 4
SpindlePole 0 0 1 2 2 0 1 4 2 2 0 1 2 1 1 1 0 – 0 0 0 0 0 0
Vac/Vac Membrane 1 0 0 0 1 6 5 13 5 8 2 2 1 5 4 2 1 – 3 6 4 3 6 5
Unique Cell Count 82 97 121 160 163 220 229 288 263 292 53 101 253 423 472 173 69 106 116 153 221 388 438
Labelled Cell Count 137 154 192 235 237 318 341 390 397 411 69 136 359 609 639 245 95 106 116 153 221 388 438


Peroxisomes

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 6.2 5.6 5.8 6.3 5.8 5.6 5.9 5.3 5.1 5.1 5.1 7.4 7.6 8.3 11.6 13.2 – 6.6 6.5 7.3
Std Deviation (1e-4) 0.9 0.8 0.9 1.5 1.5 1.1 1.3 1.4 1.2 1.5 1.2 1.6 1.4 1.2 1.7 2.5 3.4 – 1.3 1.3 1.7
Intensity Change (Log2) – – – 0.05 0.18 0.04 0.01 0.08 -0.07 -0.14 -0.12 -0.13 0.41 0.44 0.57 1.05 1.24 – 0.24 0.21 0.38


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.6 -2.1 -2.6 -3.7 -4.9 -2.7 -5.7 -3.2 -3.9 1.8 1.6 -0.6 2.0 0.2 –
Bud 1.2 0.8 0.3 0.4 0.4 0.2 0 0 0 -1.5 -2.1 -1.7 2.1 0.2 –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cell Periphery 0.6 -0.7 -1.3 -2.1 0 -1.9 0 0 0 2.5 2.9 2.1 4.7 3.3 –
Cytoplasm 0.2 -0.3 -2.1 -2.0 -0.9 -3.0 -1.2 -1.6 -0.4 -0.8 -0.4 -1.6 -2.4 -1.3 –
Endoplasmic Reticulum -4.8 -2.7 -1.8 -0.1 -3.9 -2.6 -5.2 -2.4 -2.9 0.3 -0.8 3.0 -8.0 -4.3 –
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 4.7 0 –
Mitochondria 0 -0.7 2.2 2.5 2.7 5.2 6.8 2.7 3.7 -8.1 -10.0 -11.1 -6.2 -3.9 –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Peroxisomes 2.5 2.6 0 0 0 0 0 0 0 0 2.8 0 0 0 –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.1676 3.0016 2.3024 2.2605 1.9619 2.6795 0.603 1.4443 1.0747 1.0998 1.1482 1.1771 2.3768 2.7017 2.4654 2.5637 2.2598 2.6317
Actin 0.4459 0.1848 0.2352 0.2362 0.2451 0.249 0.3705 0.1956 0.2641 0.2123 0.2259 0.2294 0.2756 0.3233 0.3645 0.1757 0.3086 0.3485
Bud 0.0031 0.0015 0.0167 0.0013 0.0012 0.0013 0.0028 0.0046 0.0134 0.004 0.0014 0.0023 0.0009 0.0017 0.009 0.0196 0.0084 0.0016
Bud Neck 0.0176 0.0171 0.0538 0.105 0.0489 0.1022 0.0092 0.0303 0.0398 0.073 0.0116 0.1316 0.0073 0.0135 0.0179 0.0269 0.032 0.1124
Bud Periphery 0.007 0.0033 0.0434 0.0039 0.0026 0.0041 0.0076 0.0068 0.0425 0.0108 0.0064 0.005 0.0013 0.0047 0.0222 0.1242 0.0277 0.0047
Bud Site 0.0579 0.0695 0.0389 0.0125 0.0039 0.0036 0.0223 0.1421 0.0303 0.0068 0.0028 0.0066 0.009 0.0827 0.035 0.013 0.0091 0.0054
Cell Periphery 0.0094 0.021 0.016 0.0151 0.0075 0.0077 0.0267 0.0152 0.0175 0.0027 0.0745 0.0155 0.0092 0.0378 0.0112 0.0383 0.0068 0.0104
Cytoplasm 0.1261 0.1053 0.0877 0.0807 0.1196 0.1039 0.0772 0.1728 0.1612 0.1475 0.0456 0.1248 0.0616 0.1855 0.1069 0.2502 0.1111 0.0844
Cytoplasmic Foci 0.0455 0.1449 0.1002 0.1456 0.0966 0.12 0.0839 0.0971 0.0703 0.1578 0.1225 0.1101 0.1072 0.0826 0.0855 0.0574 0.1186 0.1091
Eisosomes 0.0088 0.0036 0.0033 0.0033 0.0077 0.0043 0.0093 0.0027 0.0053 0.0016 0.0089 0.0032 0.0041 0.0047 0.0029 0.002 0.002 0.0056
Endoplasmic Reticulum 0.0254 0.0524 0.039 0.0371 0.0241 0.0806 0.0201 0.031 0.0209 0.0195 0.0467 0.0266 0.0452 0.0219 0.0208 0.0518 0.0221 0.0375
Endosome 0.0444 0.0559 0.0707 0.0735 0.082 0.0659 0.0992 0.0565 0.0456 0.0661 0.1182 0.0815 0.0963 0.034 0.0672 0.0481 0.0484 0.0328
Golgi 0.047 0.1 0.0833 0.0786 0.1369 0.1093 0.1163 0.0515 0.0695 0.0983 0.1366 0.0839 0.1305 0.0394 0.1041 0.0373 0.1294 0.0925
Lipid Particles 0.0407 0.1595 0.0803 0.109 0.1618 0.0923 0.0489 0.0938 0.0299 0.0238 0.1625 0.0531 0.1252 0.1338 0.0853 0.1189 0.0316 0.0759
Mitochondria 0.0145 0.0047 0.0293 0.0133 0.0107 0.0116 0.0274 0.004 0.0416 0.0496 0.0191 0.0164 0.0047 0.001 0.0063 0.0019 0.0188 0.0071
None 0.0621 0.0392 0.0702 0.0368 0.0094 0.0152 0.056 0.0772 0.1152 0.0823 0.0015 0.0749 0.0876 0.0214 0.0433 0.0113 0.0238 0.0402
Nuclear Periphery 0.0146 0.002 0.0016 0.0011 0.0031 0.0026 0.0019 0.0016 0.0017 0.0008 0.0008 0.0013 0.0047 0.0008 0.001 0.0018 0.0042 0.0006
Nucleolus 0.0011 0.0006 0.0014 0.0004 0.0005 0.0003 0.0004 0.0005 0.0004 0.0002 0.0002 0.0004 0.0003 0.0002 0.0002 0.0002 0.0012 0.0002
Nucleus 0.0057 0.0008 0.0014 0.0005 0.0008 0.0009 0.0005 0.0008 0.0009 0.0005 0.0003 0.0007 0.0009 0.0004 0.0005 0.0008 0.0088 0.0004
Peroxisomes 0.009 0.0241 0.0173 0.0348 0.0285 0.0188 0.012 0.0088 0.0224 0.0371 0.007 0.0211 0.0195 0.0058 0.0097 0.007 0.0691 0.0274
Punctate Nuclear 0.0075 0.0031 0.0045 0.002 0.0015 0.0016 0.0008 0.0016 0.0012 0.0012 0.0008 0.0011 0.0042 0.0012 0.0011 0.0009 0.0145 0.0009
Vacuole 0.0044 0.0061 0.005 0.0078 0.0065 0.0037 0.005 0.0049 0.0052 0.0028 0.0046 0.009 0.0039 0.0032 0.0047 0.0119 0.0026 0.0021
Vacuole Periphery 0.0022 0.0006 0.0009 0.0014 0.0012 0.0013 0.0019 0.0006 0.0012 0.0013 0.0021 0.0015 0.0009 0.0003 0.0008 0.0009 0.001 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.1968 13.8042 15.365 21.2829 13.6509 18.2396 20.7776 28.9033 29.8393 18.6959
Translational Efficiency 0.7965 0.9712 1.1616 1.0994 0.925 1.0735 0.8959 0.6501 0.8234 0.7743

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2278 1409 929 1233 1195 1373 307 299 3473 2782 1236 1532

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 785.14 840.76 1132.12 990.23 763.53 826.65 1083.68 1030.29 777.70 833.80 1120.09 998.05
Standard Deviation 91.34 110.54 140.81 146.45 87.84 117.21 147.86 170.20 90.73 114.10 144.12 152.21
Intensity Change Log 2 — 0.098744 0.528005 0.334814 — 0.114592 0.505182 0.432294 — 0.106579 0.516798 0.383697

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.059513 0.149948* 0.290749* 0.376072* 0.090054 0.101972* 0.293147* 0.328180* 0.070022 0.126270* 0.291345* 0.366725*
Bud Neck 0.006611 0.009228 0.013914 0.019247 0.010632 0.008377 0.016999 0.019241 0.007995 0.008808 0.014680 0.019246
Bud Site 0.016380 0.027801 0.066612 0.119646* 0.016149 0.019478 0.074142 0.108090* 0.016301 0.023693 0.068482 0.117391*
Cell Periphery 0.050702 0.029374 0.025274 0.091185 0.043584 0.017513 0.009464 0.012137 0.048253 0.023520 0.021347 0.075757
Cytoplasm 0.072355 0.058671 0.031169 0.059229 0.113482* 0.064311 0.057003 0.049663 0.086506 0.061455 0.037586 0.057362
Cytoplasmic Foci 0.039846 0.078535 0.041212 0.030200 0.060980 0.099189 0.108862 0.096258 0.047118 0.088728 0.058015 0.043092
Eisosomes 0.064942 0.031421 0.013444 0.050592 0.064526 0.024176 0.011546 0.013188 0.064799 0.027846 0.012972 0.043292
Endoplasmic Reticulum 0.036903 0.058212 0.226737* 0.078057 0.050525 0.042736 0.095353 0.039544 0.041590 0.050574 0.194104* 0.070541
Endosome 0.013193 0.048757 0.035665 0.014768 0.027150 0.080629 0.044036 0.061868 0.017995 0.064487 0.037744 0.023960
Golgi 0.059248 0.171941* 0.040539 0.027563 0.144367* 0.213788* 0.046819 0.058238 0.088536 0.192594* 0.042099 0.033549
Lipid Particles 0.112440* 0.129806* 0.175852* 0.068580 0.119810* 0.157328* 0.157865* 0.120948* 0.114976* 0.143389* 0.171385* 0.078801
Mitochondria 0.025598 0.025068 0.000691 0.003069 0.021300 0.039461 0.001185 0.002218 0.024119 0.032172 0.000814 0.002903
Mitotic Spindle 0.000168 0.000530 0.002069 0.001051 0.000244 0.000536 0.001795 0.001179 0.000194 0.000533 0.002001 0.001076
None 0.001851 0.000208 0.000216 0.000219 0.000543 0.000120 0.000064 0.000171 0.001401 0.000164 0.000178 0.000210
Nuclear Periphery 0.000054 0.000060 0.000081 0.000095 0.000092 0.000078 0.000208 0.000094 0.000067 0.000069 0.000113 0.000095
Nuclear Periphery Foci 0.000252 0.000619 0.003217 0.000996 0.001117 0.000735 0.008467 0.003948 0.000550 0.000676 0.004521 0.001572
Nucleolus 0.000034 0.000032 0.000012 0.000027 0.000055 0.000045 0.000065 0.000049 0.000042 0.000039 0.000026 0.000031
Nucleus 0.001083 0.000880 0.001547 0.002346 0.001694 0.001090 0.006081 0.002753 0.001294 0.000984 0.002673 0.002426
Peroxisomes 0.436866* 0.171918* 0.018570 0.042206 0.229340* 0.115948* 0.028719 0.041857 0.365460* 0.144295* 0.021091 0.042138
Vacuole 0.000833 0.004162 0.012012 0.013321 0.002376 0.007609 0.037159 0.038366 0.001364 0.005863 0.018258 0.018209
Vacuole Periphery 0.001127 0.002828 0.000418 0.001530 0.001979 0.004882 0.001020 0.002009 0.001420 0.003842 0.000567 0.001624

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -14.64 -21.94 -33.38* -20.99* -6.23 -1.83 -10.08 -11.80 -11.16 -1.27 -12.90 -23.61 -34.45* -26.34* -6.17
Bud Neck -2.53 -6.36 -8.47 -6.18 -3.11 1.74 -2.16 -2.61 -3.38 -0.59 -1.05 -5.89 -8.21 -7.54 -2.83
Bud Site -4.84 -13.16 -19.31 -16.52 -8.36 -1.59 -7.17 -8.55 -8.25 -2.56 -4.68 -14.94 -21.19 -19.41 -8.49
Cell Periphery 6.48 8.11 -7.40 -11.32 -12.29 7.84 10.14 8.42 1.96 -0.93 10.70 10.93 -6.12 -12.11 -12.39
Cytoplasm 4.28 12.69 3.30 -0.35 -7.39 10.01 7.25 8.24 1.68 0.63 9.21 15.36 8.21 0.86 -5.60
Cytoplasmic Foci -12.50 -0.56 3.51 14.02 3.21 -9.59 -5.52 -4.23 0.34 1.26 -16.98 -3.48 1.36 14.36 3.96
Eisosomes 13.91 24.26 4.55 -6.33 -13.34 12.74 14.63 15.64 4.87 -0.57 19.56 28.43 8.18 -6.37 -12.89
Endoplasmic Reticulum -5.46 -20.20 -8.63 -3.58 14.58 1.78 -3.97 1.91 0.61 4.76 -3.21 -19.62 -7.16 -4.65 14.66
Endosome -16.03 -10.08 -1.16 14.01 8.58 -14.55 -3.23 -5.16 2.73 -2.17 -22.24 -9.23 -3.24 15.97 5.38
Golgi -21.09* 6.03 10.39 27.20 4.21 -9.95 14.00 12.24 20.81 -1.47 -24.56 15.10 18.21 38.66 2.90
Lipid Particles -3.05 -8.06 8.83 10.05 13.13 -5.19 -2.74 -0.01 2.92 2.18 -6.31 -8.24 7.84 12.17 12.51
Mitochondria 0.26 19.19 16.57 13.24 -5.28 -5.78 13.11 10.66 12.71 -0.98 -4.29 23.30 19.90 17.85 -5.00
Mitotic Spindle -2.37 -2.16 -2.96 -1.57 1.09 -1.63 -4.47 -4.63 -2.61 1.60 -2.96 -2.71 -3.63 -2.03 1.31
None 4.10 3.82 3.95 -0.16 -0.04 2.26 2.53 1.45 -0.62 -0.99 4.57 4.16 4.18 -0.66 -0.29
Nuclear Periphery -0.57 -4.07 -3.26 -2.34 -0.91 0.75 -2.89 -0.47 -1.12 2.45 -0.15 -3.88 -2.45 -2.27 1.23
Nuclear Periphery Foci -2.92 -9.34 -4.67 -1.98 6.35 0.72 -4.18 -2.12 -2.59 2.27 -0.65 -7.58 -3.15 -3.20 5.30
Nucleolus 0.55 6.51 1.95 1.30 -4.45 0.55 -0.59 0.08 -0.33 0.58 0.42 2.13 1.17 1.22 -0.98
Nucleus 2.05 -1.45 -4.65 -5.41 -2.06 4.42 -3.81 -1.71 -2.05 0.78 3.80 -3.67 -3.87 -4.62 -0.26
Peroxisomes 32.93* 67.10* 60.61* 22.36 -8.42 14.65 28.21* 23.27 11.81 -2.29 37.22* 68.40* 60.93* 25.41 -8.35
Vacuole -4.35 -9.59 -9.17 -6.11 -0.83 -5.48 -8.03 -6.74 -5.78 -0.42 -7.36 -11.87 -10.95 -7.76 -0.19
Vacuole Periphery -5.07 3.58 -0.73 2.23 -2.16 -5.91 1.64 -0.00 3.05 -0.97 -8.16 4.19 -0.42 4.33 -2.26
Standard name
Human Ortholog
Description ER-resident protein involved in peroxisomal biogenesis; ER-localized protein that associates with peroxisomes; interacts with Pex29p and reticulons Rtn1p and Yop1p to regulate peroxisome biogenesis from the ER; role in peroxisomal-destined vesicular flow from the ER; partially redundant with Pex31p; may function at a step downstream of steps mediated by Pex28p and Pex29p; PEX30 has a paralog, PEX31, that arose from the whole genome duplication
Localization
Cell Percentages ER (45%)
Cell Cycle Regulation No
Subcompartmental Group ER-1

Pex30

Pex30


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pex30-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available