Standard name
Human Ortholog
Description Protein that may be involved in nonsense-mediated mRNA decay; interacts with Nam7p, relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0.11 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0.06 0.05 0.05 0 0 0 0 0 0
Cytoplasm 0.98 0.99 1.0 0.97 0.93 0.82 0.81 – 0.67 0.76 0.55 0.61 0.88 0.76 0.85 0.95 0.96 0.96 0.95 0.94 0.86 0.9 0.91 0.89
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0.09 0.08 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.1 0 – 0.24 0.15 0.35 0.33 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.1 0.12 0.17 – 0.13 0.11 0.14 0.11 0 0 0 0.06 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 – 0 2 1 0 6 36 8 0 0 0 0 1 1 1 0 1
Bud 1 2 0 0 0 0 1 – 1 0 4 0 1 7 2 0 0 0 0 1 0 0 0 2
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 6 1 3 0 0 1 – 1 1 5 3 2 7 3 15 14 12 0 0 0 0 0 0
Cytoplasm 153 304 38 60 86 56 104 – 90 100 89 73 171 260 220 228 266 256 155 282 68 233 279 248
Endoplasmic Reticulum 2 3 0 1 0 0 2 – 4 4 2 0 9 12 10 9 8 9 1 1 3 10 8 6
Endosome 0 0 0 0 0 0 0 – 0 1 1 1 12 30 20 0 0 0 1 1 0 3 0 3
Golgi 1 0 0 0 1 0 2 – 0 0 0 0 2 15 3 2 2 0 0 0 0 0 3 1
Mitochondria 0 0 0 0 0 7 1 – 32 20 56 39 0 0 0 1 0 1 0 2 1 0 1 0
Nucleus 0 2 0 0 0 0 2 – 2 2 5 2 0 0 0 1 3 5 0 1 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 1 0 1 2 1
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 1 – 0 0 0 0 1 10 6 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 0 0 9 8 22 – 18 14 23 13 2 2 3 14 8 8 0 4 1 3 6 6
Unique Cell Count 156 307 38 62 92 68 128 134 132 162 119 195 340 259 241 276 266 164 301 79 260 306 278
Labelled Cell Count 163 318 39 64 97 71 136 148 144 188 132 206 379 276 270 301 291 164 301 79 260 306 278


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.1 12.3 12.7 12.0 13.5 7.7 9.5 – 8.0 8.6 7.5 7.6 13.6 14.0 14.1 17.6 18.5 18.3 11.4 12.2 13.0
Std Deviation (1e-4) 2.4 2.0 2.0 1.4 4.1 1.9 2.0 – 1.5 1.9 1.3 1.4 2.0 2.0 2.2 4.3 3.8 3.6 1.8 2.1 2.2
Intensity Change (Log2) – – – -0.08 0.08 -0.73 -0.43 – -0.67 -0.57 -0.76 -0.74 0.1 0.14 0.15 0.47 0.54 0.52 -0.15 -0.06 0.03


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.1 -1.6 -2.7 -2.9 – -4.1 -3.4 -5.2 -4.6 -2.3 -3.4 -2.6 -1.5 -1.2 -1.2
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 3.3 0 4.3 4.1 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 2.7 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.5545 8.0813 7.3275 6.4079 6.4792 7.0319 7.4053 9.8864 8.7961 7.6917 7.7698 9.1072 12.3047 13.959 13.4194 12.6101 11.9188 13.2213
Actin 0.0087 0.0003 0.0033 0.0002 0.0002 0.0005 0.0262 0.0012 0.0215 0.0037 0.0319 0.0034 0.0042 0.0003 0.0004 0.0003 0.0002 0.0002
Bud 0.0003 0.0002 0.0002 0.0002 0.0009 0.0001 0.0005 0.0001 0.0002 0.0007 0.0016 0.0002 0.0001 0 0.0001 0.0001 0.0001 0
Bud Neck 0.0009 0.0001 0.0003 0.0003 0.0005 0.0007 0.0017 0.0002 0.0006 0.0025 0.0008 0.0014 0.0002 0.0001 0.0002 0.0003 0.0003 0.0006
Bud Periphery 0.0002 0.0001 0.0002 0 0.0001 0 0.0006 0 0 0.001 0.0018 0.0001 0 0 0 0 0 0
Bud Site 0.0008 0.0007 0.0005 0.0001 0.0015 0 0.0019 0.0002 0.0022 0.0007 0.0037 0.0001 0.0001 0.0001 0.0001 0.0001 0 0
Cell Periphery 0.0001 0.0002 0.0001 0 0.0001 0 0.0003 0.0001 0.0001 0.0002 0.0003 0 0 0 0 0 0 0
Cytoplasm 0.901 0.9836 0.9639 0.9746 0.9437 0.9638 0.8126 0.9872 0.9273 0.8707 0.7498 0.9438 0.9185 0.9907 0.9883 0.9696 0.9779 0.9807
Cytoplasmic Foci 0.0126 0.0024 0.0072 0.0039 0.0115 0.0054 0.0245 0.0024 0.0184 0.0336 0.0245 0.0072 0.0134 0.0019 0.0021 0.0068 0.0032 0.0034
Eisosomes 0.0002 0 0.0001 0 0 0 0.0002 0 0.0001 0.0001 0.0002 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0169 0.0033 0.0036 0.0032 0.0022 0.0082 0.0142 0.0029 0.0059 0.0031 0.01 0.0109 0.0156 0.0022 0.0034 0.0018 0.0074 0.0055
Endosome 0.0226 0.0018 0.0088 0.007 0.0194 0.0103 0.0227 0.0015 0.0069 0.0332 0.0622 0.0177 0.0065 0.0013 0.0014 0.014 0.0027 0.0038
Golgi 0.0024 0.0002 0.001 0.0002 0.0003 0.0007 0.01 0.0002 0.0019 0.006 0.036 0.0028 0.0011 0.0005 0.0001 0.0015 0.0001 0.0001
Lipid Particles 0.0021 0.0001 0.0004 0 0 0.0005 0.0125 0 0.0025 0.0007 0.0132 0.0008 0.0039 0 0 0 0 0
Mitochondria 0.0027 0.0001 0.0009 0.0002 0.0002 0.0006 0.0047 0.0001 0.0004 0.0329 0.039 0.0008 0.0004 0.0001 0.0001 0.0002 0.0001 0.0002
None 0.0081 0.001 0.0039 0.0014 0.0084 0.0009 0.0077 0.0013 0.0032 0.002 0.0033 0.001 0.0071 0.0006 0.0011 0.0011 0.0028 0.001
Nuclear Periphery 0.0062 0.0014 0.0013 0.002 0.0014 0.0031 0.0109 0.0008 0.0016 0.001 0.0048 0.0051 0.0055 0.0006 0.0007 0.0008 0.0015 0.0016
Nucleolus 0.0017 0 0.0001 0 0.0001 0 0.0009 0 0.0001 0.0001 0.0003 0 0.0001 0 0 0 0 0
Nucleus 0.0046 0.0033 0.0017 0.0035 0.0035 0.0029 0.0164 0.0012 0.0022 0.0016 0.0025 0.0021 0.0051 0.0012 0.0013 0.0018 0.0027 0.0022
Peroxisomes 0.0011 0 0.0004 0 0.0001 0.0001 0.0107 0 0.0031 0.0021 0.0061 0.0002 0.0094 0 0 0 0 0
Punctate Nuclear 0.0037 0.0001 0.0006 0.0003 0.0012 0.0003 0.0091 0.0002 0.0006 0.0007 0.0021 0.0004 0.0043 0.0001 0.0001 0.0001 0.0001 0.0001
Vacuole 0.0023 0.0007 0.0011 0.0023 0.0036 0.0013 0.0093 0.0003 0.0009 0.0023 0.0036 0.0012 0.0023 0.0002 0.0004 0.001 0.0006 0.0005
Vacuole Periphery 0.0007 0.0002 0.0004 0.0005 0.0011 0.0005 0.0027 0.0001 0.0002 0.0009 0.0025 0.0006 0.0023 0 0.0001 0.0003 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.1151 22.52 16.7108 19.3887 14.1537 10.0712 20.1135 22.0277 19.5204 24.1972
Translational Efficiency 1.6358 1.0432 1.2616 1.4612 1.5663 2.6364 1.5015 1.3666 1.6602 1.4106

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
109 1347 1525 1650 1973 107 1688 2267 2082 1454 3213 3917

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1126.87 1177.58 1554.44 1642.33 1049.63 1240.38 1501.43 1754.99 1053.67 1182.20 1526.59 1707.53
Standard Deviation 179.22 189.54 229.92 288.84 144.35 132.98 208.16 280.12 147.39 186.69 220.36 289.23
Intensity Change Log 2 — 0.063504 0.464074 0.543423 — 0.240901 0.516456 0.741582 — 0.151780 0.489573 0.642387

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001885 0.000783 0.000248 0.000878 0.000612 0.000810 0.000322 0.000484 0.000678 0.000785 0.000287 0.000650
Bud Neck 0.001604 0.001137 0.001113 0.001861 0.001460 0.001773 0.001061 0.001461 0.001467 0.001184 0.001086 0.001629
Bud Site 0.057621 0.028871 0.004674 0.020591 0.019372 0.033223 0.009986 0.013949 0.021375 0.029192 0.007465 0.016747
Cell Periphery 0.000583 0.000151 0.000087 0.000486 0.000156 0.000194 0.000166 0.000140 0.000179 0.000155 0.000128 0.000286
Cytoplasm 0.367328* 0.748714* 0.883358* 0.849732* 0.652367* 0.507015* 0.883428* 0.882515* 0.637445* 0.730928* 0.883395* 0.868705*
Cytoplasmic Foci 0.422771* 0.141775 0.015638 0.029469 0.231005* 0.288151* 0.030886 0.024214 0.241045* 0.152546 0.023649 0.026428
Eisosomes 0.000069 0.000010 0.000002 0.000004 0.000025 0.000032 0.000003 0.000003 0.000027 0.000012 0.000002 0.000004
Endoplasmic Reticulum 0.022969 0.003098 0.000620 0.000456 0.008728 0.005598 0.000572 0.000222 0.009474 0.003282 0.000595 0.000320
Endosome 0.022000 0.009129 0.002301 0.002834 0.011316 0.039770 0.003511 0.002760 0.011876 0.011384 0.002937 0.002792
Golgi 0.028715 0.014601 0.001704 0.006391 0.017840 0.012324 0.004045 0.003225 0.018409 0.014434 0.002934 0.004558
Lipid Particles 0.008548 0.002551 0.001497 0.007211 0.002819 0.005473 0.003559 0.003811 0.003119 0.002766 0.002581 0.005243
Mitochondria 0.001384 0.000636 0.000079 0.000290 0.002236 0.000195 0.000042 0.000199 0.002192 0.000603 0.000060 0.000237
Mitotic Spindle 0.002291 0.002635 0.013460 0.007597 0.001637 0.000952 0.004182 0.006625 0.001672 0.002512 0.008586 0.007035
None 0.000094 0.000900 0.001811 0.000968 0.000959 0.000095 0.000664 0.000878 0.000914 0.000841 0.001208 0.000916
Nuclear Periphery 0.000583 0.000080 0.000263 0.000068 0.000127 0.000066 0.000059 0.000060 0.000151 0.000079 0.000156 0.000063
Nuclear Periphery Foci 0.004168 0.002574 0.004573 0.003894 0.000806 0.002659 0.004404 0.002116 0.000982 0.002581 0.004484 0.002865
Nucleolus 0.000319 0.000174 0.000116 0.000155 0.000120 0.000069 0.000102 0.000199 0.000131 0.000166 0.000109 0.000181
Nucleus 0.006101 0.006587 0.043308 0.013616 0.007784 0.005195 0.011089 0.013933 0.007696 0.006485 0.026382 0.013799
Peroxisomes 0.002107 0.001927 0.000072 0.001263 0.000916 0.002862 0.000238 0.000738 0.000978 0.001996 0.000159 0.000959
Vacuole 0.033422 0.028976 0.024433 0.049167 0.032964 0.090972 0.040638 0.041517 0.032988 0.033539 0.032947 0.044739
Vacuole Periphery 0.015437 0.004688 0.000642 0.003069 0.006750 0.002575 0.001042 0.000950 0.007205 0.004532 0.000852 0.001843

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.58 3.82 1.81 -0.81 -2.76 -0.81 1.09 -0.40 0.49 -1.45 -0.75 2.37 -0.82 -0.19 -3.12
Bud Neck 1.35 -0.38 -2.41 -7.81 -3.57 -1.01 0.73 -4.12 -1.48 -5.27 1.79 -0.51 -5.60 -8.47 -6.04
Bud Site 4.30 8.12 5.63 3.42 -9.97 -2.30 6.48 2.66 3.01 -3.78 -3.57 10.36 2.64 5.76 -9.79
Cell Periphery 4.58 5.06 1.24 -2.53 -2.97 -1.01 -0.82 0.99 1.33 1.55 1.91 3.25 -1.75 -2.31 -2.65
Cytoplasm -13.50 -17.51 -16.07 -7.42 5.66 5.20 -29.65 -26.70 -12.28 3.63 -9.90 -32.89 -28.46 -13.10 6.23
Cytoplasmic Foci 11.69 17.18 16.59 22.12 -7.97 -2.87 40.84 41.87 13.44 2.30 13.28 45.30 44.25 25.39 -3.00
Eisosomes 4.33 4.88 4.72 5.24 -5.16 -0.86 11.82 11.05 3.59 -1.91 7.13 12.80 11.90 6.83 -4.42
Endoplasmic Reticulum 2.98 3.36 3.39 5.83 1.80 1.15 7.88 8.20 2.06 3.66 5.43 8.50 8.79 6.44 3.80
Endosome 4.31 6.68 6.63 8.89 -0.51 -4.45 12.57 13.42 5.81 1.72 0.48 14.85 15.23 10.27 1.03
Golgi 3.98 7.84 6.79 8.88 -4.35 1.15 18.64 19.13 1.95 1.83 3.74 22.49 19.36 11.47 -1.98
Lipid Particles 1.71 1.86 0.09 -7.81 -8.80 -1.04 -3.90 -5.82 0.05 -2.00 0.92 -0.27 -7.82 -8.03 -8.01
Mitochondria 1.61 3.34 2.94 1.58 -1.46 3.25 3.55 3.35 0.24 -3.68 2.50 3.63 3.42 1.76 -2.93
Mitotic Spindle -0.45 -7.23 -4.20 -4.21 2.61 1.54 -3.77 -5.78 -6.54 -2.41 -1.75 -8.52 -7.33 -6.29 0.83
None -3.84 -14.28 -5.75 0.04 5.04 5.52 1.78 0.49 -12.50 -2.38 0.32 -1.69 0.21 -0.22 3.25
Nuclear Periphery 1.21 0.50 1.16 -1.20 10.16 0.80 0.62 0.27 -2.58 -3.67 0.92 -0.75 0.60 -1.65 8.27
Nuclear Periphery Foci 0.88 -0.54 -0.07 -4.66 1.95 -2.42 -12.61 -8.10 -0.52 5.50 -4.80 -14.30 -10.96 -3.06 5.43
Nucleolus 0.66 0.80 0.67 0.02 -1.22 4.10 0.94 -8.90 -10.86 -9.92 -1.00 0.13 -4.84 -1.20 -6.70
Nucleus -0.17 -13.82 -3.99 -9.31 16.70 2.77 -9.82 -13.75 -12.05 -5.59 1.74 -25.24 -15.07 -14.79 11.90
Peroxisomes 0.34 5.37 2.05 1.75 -4.02 -1.75 6.92 0.97 1.87 -5.66 -2.98 8.85 0.18 2.97 -6.16
Vacuole 0.55 -1.25 -5.95 -13.79 -9.28 -4.86 -6.84 -11.63 2.29 -4.27 -0.59 -6.48 -16.19 -12.89 -9.51
Vacuole Periphery 2.36 3.30 2.92 3.04 -3.64 6.29 10.88 11.13 4.31 1.33 3.24 11.54 9.88 4.80 -3.17
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that may be involved in nonsense-mediated mRNA decay; interacts with Nam7p, relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-5

Nmd4

Nmd4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nmd4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available