Standard name
Human Ortholog
Description Phosphatidylinositol transfer protein; has a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.24 0.13 0.16 0.38 0.31 0.14 0.12 0.07 0.12 0.1 0.17 0.1 0.11 0.13 0.13 0.12 0.07 0.16 0 0 0 0 0 0
Cytoplasm 0.98 0.96 0.98 0.92 0.89 0.95 0.86 0.89 0.86 0.87 0.86 0.85 1.0 0.98 0.99 0.96 0.97 0.96 0.92 0.96 0.92 0.91 0.9 0.89
Endoplasmic Reticulum 0 0 0 0.05 0.06 0 0.07 0 0.07 0.05 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.05 0.05 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 3 3 1 0 1 8 2 5 5 0 0 0 1 1 1 2 2 4 0 1 2
Bud 2 4 2 2 1 15 12 11 5 14 10 20 0 0 0 0 1 0 0 0 0 0 0 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 3 3
Bud Site 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 84 62 81 119 149 83 91 52 76 71 116 89 19 33 34 30 17 32 4 2 6 1 6 5
Cytoplasm 349 442 511 289 429 554 671 655 542 625 585 743 176 239 262 249 232 194 345 448 476 158 211 239
Endoplasmic Reticulum 6 15 7 17 29 13 56 28 47 36 40 42 0 6 3 8 4 2 6 3 16 2 2 7
Endosome 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 1 3 2 2 0 0 1
Golgi 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 1
Mitochondria 0 1 1 1 1 8 18 20 34 33 40 65 0 0 1 4 2 1 2 1 1 1 0 0
Nucleus 3 4 2 1 4 0 2 7 1 3 1 4 0 3 1 3 0 6 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 2 2 1 1 0 3 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 1 2 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0
Vac/Vac Membrane 1 2 1 4 4 9 32 31 11 26 5 29 0 0 1 5 4 1 3 1 3 3 3 1
Unique Cell Count 356 461 519 314 480 585 782 740 633 721 680 877 176 245 265 259 238 203 375 468 520 173 235 268
Labelled Cell Count 445 530 605 436 620 683 886 810 725 812 803 1003 195 281 302 301 262 239 375 468 520 173 235 268


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 16.2 14.1 11.8 11.2 11.3 11.0 10.8 10.6 10.9 10.5 10.3 9.9 13.8 13.5 13.2 15.6 15.6 16.0 14.3 15.1 15.9
Std Deviation (1e-4) 2.5 2.5 2.3 2.0 1.9 1.9 2.1 2.0 2.1 2.0 1.8 2.2 2.0 1.9 1.8 5.8 3.7 4.3 2.5 2.5 2.7
Intensity Change (Log2) – – – -0.07 -0.06 -0.1 -0.13 -0.15 -0.11 -0.16 -0.19 -0.25 0.22 0.2 0.17 0.41 0.4 0.44 0.28 0.36 0.44

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 2.9 2.0 1.9 0 2.4 1.9 2.7 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 7.3 5.8 -0.7 -2.1 -4.9 -1.8 -3.1 0.7 -3.0 -1.6 -0.8 -1.0 -1.5 -3.2 0.1
Cytoplasm -4.6 -6.1 -3.4 -7.8 -6.6 -7.7 -7.4 -7.6 -8.2 1.7 -0.9 0.5 -2.0 -0.9 -2.3
Endoplasmic Reticulum 3.4 4.0 1.1 4.8 2.6 4.9 3.5 4.0 3.4 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 3.1 3.4 5.1 4.7 5.4 6.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 4.4 4.4 2.6 4.1 0 3.9 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.9614 8.4206 6.9634 6.272 6.3368 7.1252 10.3579 12.6265 11.8536 11.9997 11.3209 11.2195 10.0264 11.0256 10.4368 9.003 9.8728 10.2103
Actin 0.0392 0.0072 0.0177 0.0684 0.0344 0.0061 0.0199 0.0015 0.0016 0.0016 0.0101 0.0037 0.0006 0.0007 0.0027 0.0138 0.0004 0.0009
Bud 0.0007 0.0079 0.0016 0.0017 0.0015 0.0103 0.0005 0.0001 0.0001 0.0002 0.0003 0.0002 0 0.0001 0.0001 0.0001 0 0
Bud Neck 0.0033 0.0007 0.002 0.0034 0.0034 0.006 0.0016 0.0004 0.0015 0.0009 0.0015 0.006 0.0004 0.0004 0.0009 0.0009 0.0009 0.0096
Bud Periphery 0.001 0.0027 0.0019 0.003 0.0026 0.0052 0.0005 0.0001 0.0001 0.0002 0.0003 0.0002 0.0001 0 0.0001 0 0 0
Bud Site 0.0038 0.0243 0.0135 0.0066 0.0049 0.0012 0.0032 0.0031 0.0015 0.0002 0.0006 0.0007 0.0002 0.0034 0.0003 0.0003 0.0001 0.0001
Cell Periphery 0.0015 0.001 0.0011 0.0013 0.0015 0.0009 0.0019 0.0011 0.0009 0.0006 0.0004 0.0003 0.0009 0.0004 0.0002 0.0002 0.0001 0.0002
Cytoplasm 0.8402 0.9314 0.8771 0.8161 0.813 0.921 0.9133 0.9806 0.9809 0.9727 0.8924 0.9703 0.9727 0.9909 0.9738 0.9564 0.9887 0.983
Cytoplasmic Foci 0.0115 0.0011 0.0117 0.0327 0.0181 0.011 0.0164 0.0013 0.0036 0.0028 0.0169 0.004 0.0004 0.0004 0.0025 0.0122 0.001 0.0005
Eisosomes 0.0003 0 0.0004 0.0003 0.0001 0 0.0001 0 0 0 0.0002 0 0.0001 0 0 0.0001 0 0
Endoplasmic Reticulum 0.0092 0.0075 0.0043 0.01 0.0078 0.0042 0.0054 0.0025 0.003 0.0104 0.0193 0.0045 0.0082 0.0014 0.0026 0.0055 0.0042 0.0032
Endosome 0.0249 0.0002 0.0136 0.0083 0.039 0.0048 0.0057 0.0004 0.0018 0.0014 0.0166 0.0008 0.0027 0.0001 0.0014 0.0009 0.0005 0.0001
Golgi 0.0059 0.0001 0.0105 0.0064 0.0139 0.0035 0.0037 0.0001 0.0007 0.0004 0.0042 0.0004 0.0003 0 0.0006 0.0006 0 0
Lipid Particles 0.0181 0.0001 0.0069 0.0126 0.0197 0.0042 0.0013 0.0001 0.0001 0.0004 0.009 0.0002 0.0006 0 0.0034 0.0005 0 0
Mitochondria 0.0158 0.0005 0.0082 0.0019 0.0109 0.0031 0.0013 0 0.0002 0.0001 0.0006 0.0001 0.002 0 0.0002 0.0001 0 0
None 0.0056 0.0021 0.0162 0.0082 0.0014 0.0033 0.0184 0.006 0.0018 0.0055 0.0209 0.0053 0.0023 0.0009 0.007 0.0062 0.0019 0.0008
Nuclear Periphery 0.004 0.001 0.0011 0.0014 0.0077 0.0021 0.0007 0.0005 0.0003 0.0004 0.0017 0.0004 0.0036 0.0002 0.0006 0.0004 0.0005 0.0002
Nucleolus 0.0022 0.0002 0.0004 0.0003 0.0011 0.0005 0.0001 0 0 0 0 0 0.0005 0 0.0001 0 0 0
Nucleus 0.0026 0.0113 0.0021 0.0023 0.0048 0.0095 0.0011 0.0015 0.0011 0.0017 0.0015 0.001 0.0022 0.0009 0.0008 0.0006 0.0011 0.001
Peroxisomes 0.0028 0.0001 0.0038 0.0121 0.0014 0.0009 0.0027 0 0.0003 0 0.0016 0.0006 0 0 0.001 0.0004 0 0
Punctate Nuclear 0.0042 0.0004 0.0017 0.0023 0.0015 0.0009 0.0008 0.0004 0.0001 0.0002 0.0009 0.0012 0.0002 0.0001 0.0014 0.0006 0.0002 0.0001
Vacuole 0.0025 0.0003 0.0037 0.0007 0.0083 0.0009 0.0011 0.0003 0.0003 0.0004 0.001 0.0002 0.001 0.0001 0.0002 0.0002 0.0002 0.0001
Vacuole Periphery 0.0009 0 0.0006 0.0002 0.0031 0.0004 0.0002 0 0 0 0.0002 0 0.0011 0 0.0001 0 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 90.3766 84.4087 55.4766 47.8286 71.7055 78.1932 65.838 54.8595 51.2588 70.089
Translational Efficiency 0.9647 0.8645 0.8931 0.864 1.008 1.0923 0.9763 0.9432 1.186 1.2329

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1216 1636 529 1598 1410 1617 2075 1648 2626 3253 2604 3246

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1007.65 1158.11 1713.81 1722.54 1073.18 1164.17 1461.84 1717.87 1042.84 1161.12 1513.03 1720.17
Standard Deviation 142.95 201.57 241.28 313.12 195.44 180.78 204.00 296.13 176.18 191.54 235.09 304.62
Intensity Change Log 2 — 0.200778 0.766213 0.773543 — 0.117410 0.445893 0.678729 — 0.158383 0.609893 0.725421

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003082 0.002974 0.023094 0.013597 0.002618 0.008552 0.009663 0.011446 0.002833 0.005746 0.012392 0.012505
Bud Neck 0.010273 0.009060 0.033137 0.012072 0.011412 0.011417 0.012799 0.009291 0.010885 0.010232 0.016931 0.010660
Bud Site 0.076208 0.073824 0.161772 0.147810 0.078794 0.111770 0.087428 0.115707 0.077597 0.092686 0.102531 0.131512
Cell Periphery 0.005343 0.003175 0.045995 0.017369 0.003105 0.007755 0.004451 0.013995 0.004141 0.005451 0.012890 0.015656
Cytoplasm 0.730500 0.784058 0.429745 0.643614 0.752743 0.716735 0.773000 0.732713 0.742443 0.750593 0.703268 0.688850
Cytoplasmic Foci 0.077266 0.049175 0.038713 0.019042 0.054664 0.057362 0.015719 0.016337 0.065130 0.053245 0.020390 0.017669
Eisosomes 0.000516 0.000206 0.000511 0.000206 0.000391 0.000598 0.000189 0.000133 0.000449 0.000401 0.000254 0.000169
Endoplasmic Reticulum 0.006550 0.000747 0.002355 0.000477 0.001613 0.002331 0.000243 0.000414 0.003899 0.001534 0.000672 0.000445
Endosome 0.003293 0.001664 0.002116 0.003016 0.003183 0.004207 0.000581 0.001864 0.003234 0.002928 0.000893 0.002431
Golgi 0.004246 0.001904 0.001560 0.006584 0.001625 0.005836 0.000764 0.002718 0.002839 0.003859 0.000926 0.004621
Lipid Particles 0.003881 0.003237 0.067994 0.020058 0.001902 0.004991 0.005372 0.015437 0.002818 0.004109 0.018093 0.017712
Mitochondria 0.001057 0.000243 0.000057 0.002024 0.000225 0.001863 0.000152 0.000324 0.000611 0.001048 0.000133 0.001161
Mitotic Spindle 0.000607 0.000636 0.000766 0.009452 0.000157 0.000915 0.000588 0.004081 0.000365 0.000775 0.000625 0.006725
None 0.003459 0.003298 0.001211 0.000970 0.004417 0.000930 0.001337 0.000818 0.003973 0.002121 0.001311 0.000893
Nuclear Periphery 0.000118 0.000025 0.000242 0.000078 0.000033 0.000026 0.000049 0.000056 0.000072 0.000025 0.000088 0.000067
Nuclear Periphery Foci 0.006373 0.004314 0.016853 0.003115 0.002800 0.003110 0.002523 0.003180 0.004454 0.003715 0.005434 0.003148
Nucleolus 0.000235 0.000221 0.000066 0.000084 0.000326 0.000125 0.000171 0.000114 0.000284 0.000174 0.000149 0.000099
Nucleus 0.013272 0.016708 0.038478 0.012843 0.019874 0.010665 0.026189 0.011954 0.016817 0.013704 0.028686 0.012392
Peroxisomes 0.001269 0.001300 0.000666 0.002067 0.001205 0.002168 0.001060 0.001388 0.001234 0.001731 0.000980 0.001722
Vacuole 0.050066 0.042943 0.134480 0.083266 0.058274 0.048147 0.057452 0.057421 0.054473 0.045530 0.073100 0.070145
Vacuole Periphery 0.002388 0.000289 0.000187 0.002257 0.000639 0.000498 0.000270 0.000607 0.001449 0.000393 0.000254 0.001419

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.43 -10.06 -7.22 -7.47 5.21 -9.89 -8.53 -8.87 -2.00 -0.77 -8.38 -11.93 -11.39 -6.49 1.49
Bud Neck 1.53 -12.00 0.84 -0.96 13.14 -0.12 0.01 2.97 3.26 3.39 1.03 -5.81 2.79 1.85 9.22
Bud Site 0.87 -8.48 -6.00 -7.21 4.30 -7.22 -1.08 -5.34 1.82 -4.88 -4.77 -4.97 -8.00 -3.69 -3.02
Cell Periphery 5.99 -10.23 -3.77 -6.03 8.18 -6.90 -2.46 -7.09 -2.29 -6.30 -3.30 -8.72 -7.76 -5.74 -0.15
Cytoplasm -7.73 24.39 14.09 21.78 -14.19 4.98 0.59 5.89 1.30 5.66 -1.53 9.93 14.29 16.18 3.26
Cytoplasmic Foci 8.44 6.53 17.28 10.62 8.09 -0.80 14.79 13.40 14.60 -1.22 5.21 19.77 21.52 17.91 2.12
Eisosomes 7.04 1.94 8.57 3.53 7.57 -3.97 5.66 7.12 12.38 4.31 1.43 7.60 11.06 12.54 7.28
Endoplasmic Reticulum 4.15 3.06 4.46 3.06 6.09 -1.00 2.05 1.90 5.42 -0.72 3.12 4.39 4.81 6.12 3.44
Endosome 5.12 2.77 2.72 -1.53 0.31 -1.31 6.67 3.43 3.82 -3.24 0.81 9.11 4.31 2.74 -4.25
Golgi 4.05 6.42 1.00 -1.41 -2.05 -4.45 3.28 -0.57 3.49 -2.04 -1.79 6.73 0.42 1.67 -3.14
Lipid Particles 1.19 -13.15 -9.43 -9.77 9.43 -6.14 -9.39 -12.71 -9.33 -8.07 -4.09 -13.91 -15.32 -13.51 0.40
Mitochondria 1.79 2.20 0.08 -1.45 -1.80 -2.22 3.40 -0.10 2.17 -0.76 -1.03 2.34 -0.01 0.95 -1.86
Mitotic Spindle -0.18 -1.58 -4.54 -4.36 -4.25 -1.76 -1.68 -3.23 -2.28 -2.67 -1.35 -1.42 -5.59 -4.87 -5.09
None 0.32 3.48 3.92 7.10 1.33 4.74 4.34 4.90 0.67 2.62 3.60 5.51 6.28 6.56 3.00
Nuclear Periphery 1.50 -2.74 -0.48 -12.16 7.52 1.80 -1.89 -5.99 -6.87 -0.36 1.62 -1.22 -1.25 -13.85 0.15
Nuclear Periphery Foci 3.10 -10.02 4.32 1.59 12.80 -0.95 -0.90 -3.59 -1.79 -2.94 1.66 -4.61 1.63 -0.23 6.75
Nucleolus 0.64 9.07 6.35 8.54 -3.30 2.25 1.35 2.04 0.11 0.58 2.25 1.69 3.07 2.23 0.62
Nucleus -4.29 -11.71 -6.96 -3.32 8.91 10.83 -9.18 3.14 -6.92 11.68 4.97 -16.00 -2.32 -6.76 13.79
Peroxisomes -0.29 8.88 -1.46 -1.33 -4.98 -5.25 2.10 -0.38 4.37 -1.98 -4.79 4.08 -1.41 2.16 -3.96
Vacuole 2.35 -17.64 -22.98 -24.51 0.23 3.77 -5.76 -8.17 -12.50 -3.52 4.52 -15.11 -22.47 -26.62 -8.70
Vacuole Periphery 2.27 2.39 1.28 -2.52 -2.86 0.50 1.45 0.57 0.24 -1.39 2.33 2.69 1.35 -2.18 -2.98
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphatidylinositol transfer protein; has a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

Csr1

Csr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Csr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available