Standard name
Human Ortholog
Description Protein of unknown function; not an essential gene; YLR413W has a paralog, FAT3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.11 0.06 0.11 0.19 0.39 0.4 0.32 – 0.28 0.32 0.28 0.11 0.11 0.1 0.13 0.17 0.14 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.08 0.12 – 0.1 0.1 0.1 0 0 0 0 0.09 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.89 0.92 0.91 0.89 0.83 0.68 0.56 0.4 – 0.42 0.41 0.38 0.94 0.94 0.91 0.68 0.59 0.77 0.92 0.88 0.94 0.86 0.91 0.91
Cytoplasm 0.07 0.08 0.06 0 0.07 0.11 0.11 0.17 – 0.27 0.28 0.28 0.07 0.07 0.06 0.31 0.32 0.2 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0.05 0.05 0.09 0.13 0.12 – 0.07 0.05 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.09 0.08 0.11 – 0.19 0.24 0.19 0 0 0 0.09 0.05 0.06 0 0 0 0.08 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0.05 0.06 0.07 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.07 – 0.06 0.07 0.12 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 24 19 22 66 122 199 160 – 134 175 181 32 33 26 34 59 35 3 3 4 2 3 4
Bud 1 0 0 0 7 12 41 59 – 50 54 64 0 0 0 10 31 4 1 7 7 3 9 12
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Bud Site 1 0 0 0 4 9 6 12 – 9 9 8 0 0 0 0 2 0 – – – – – –
Cell Periphery 124 204 299 174 281 216 281 198 – 202 228 243 276 276 228 184 207 194 166 257 394 135 413 445
Cytoplasm 10 17 20 7 24 34 53 84 – 131 152 183 20 20 14 84 113 49 3 8 1 0 1 2
Endoplasmic Reticulum 3 3 9 10 18 30 64 62 – 33 28 61 5 5 6 12 11 8 2 1 1 1 2 3
Endosome 1 0 0 0 0 3 4 1 – 6 3 2 0 0 0 0 1 1 0 0 1 0 0 0
Golgi 0 0 1 2 1 0 0 3 – 0 0 0 2 2 1 0 0 1 0 1 0 0 1 0
Mitochondria 1 4 6 5 10 28 39 55 – 90 130 120 0 0 0 25 18 16 2 6 8 12 17 13
Nucleus 0 0 0 0 1 0 4 7 – 5 10 9 1 1 0 5 3 0 0 0 0 0 0 0
Nuclear Periphery 0 0 1 0 1 0 8 14 – 14 5 11 0 0 0 0 1 0 0 0 0 0 0 0
Nucleolus 0 1 0 0 0 0 0 17 – 4 4 5 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 3 7 11 4 – 8 6 7 0 0 0 0 0 1 0 0 0 0 0 0
SpindlePole 1 0 0 0 7 17 30 37 – 17 16 25 0 0 0 1 2 1 0 0 0 0 0 0
Vac/Vac Membrane 1 0 0 0 0 3 15 35 – 31 40 75 0 0 0 1 4 1 1 1 0 0 3 1
Unique Cell Count 140 222 330 195 339 316 498 501 482 552 648 294 294 251 270 351 251 181 294 419 157 455 487
Labelled Cell Count 145 253 355 220 423 481 755 748 734 860 994 336 337 275 356 452 311 181 294 419 157 455 487


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 42.5 44.1 40.5 40.8 30.1 23.2 20.1 17.9 – 14.1 14.6 13.3 37.3 37.3 37.6 13.0 16.6 20.1 48.3 46.8 46.4
Std Deviation (1e-4) 12.2 15.5 12.0 11.5 11.4 11.3 10.2 9.3 – 8.4 8.2 7.6 11.3 11.3 11.6 4.7 6.4 7.6 14.5 14.3 14.4
Intensity Change (Log2) – – – 0.01 -0.43 -0.81 -1.01 -1.17 – -1.52 -1.47 -1.61 -0.12 -0.12 -0.1 -1.64 -1.29 -1.01 0.25 0.21 0.2

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000204060WT3HU80HU120HU1600204060WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 2.3 5.3 10.1 10.9 9.0 – 7.9 9.0 8.1 2.3 2.5 2.1 2.9 4.5 3.4
Bud 0 0 3.6 5.3 6.5 – 6.0 5.9 5.9 0 0 0 0 5.5 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery -0.5 -2.9 -7.0 -10.5 -14.7 – -14.0 -14.4 -15.8 1.5 1.5 0.1 -6.9 -9.4 -4.4
Cytoplasm -1.2 0.5 2.2 2.3 4.6 – 7.6 7.8 8.1 0.4 0.4 -0.2 8.1 8.6 5.0
Endoplasmic Reticulum 1.4 1.7 3.6 5.0 4.9 – 2.6 1.7 3.8 -0.9 -0.9 -0.3 1.1 0.3 0.3
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 1.0 4.0 3.7 5.0 – 7.3 8.6 7.4 0 0 0 4.1 2.3 2.9
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 2.6 – 2.7 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 3.4 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 4.3 4.5 5.1 – 3.4 3.1 3.6 0 0 0 0 0 0
Vacuole 0 0 0 3.2 4.9 – 4.7 5.0 6.4 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 39.9112 60.1887 54.0892 57.3234 44.0132 58.8128 42.7298 65.1996 56.5994 55.2581 48.5005 59.7619 45.4646 71.0986 64.8378 57.0571 62.873 66.5257
Actin 0.027 0 0.0072 0 0.0023 0.0008 0.0239 0.0001 0.0002 0.0059 0.0029 0.0036 0.0105 0 0.0029 0.0014 0.0004 0.0001
Bud 0.0021 0 0.0008 0.0001 0.0003 0.0001 0.0016 0.0003 0.0006 0.0005 0.0014 0.0001 0.0011 0 0.0001 0.001 0.0001 0.0004
Bud Neck 0.0011 0.0001 0.0009 0.0002 0.0005 0.0018 0.0011 0.0002 0.0006 0.0015 0.002 0.0003 0.0009 0.0001 0.0003 0.0003 0.0003 0.0011
Bud Periphery 0.0083 0.0003 0.002 0.0011 0.0014 0.0014 0.0085 0.0016 0.0021 0.0017 0.0031 0.0014 0.0052 0.0002 0.0005 0.0038 0.0005 0.0027
Bud Site 0.0132 0.0048 0.0079 0.0005 0.0027 0.0002 0.0198 0.0072 0.0064 0.0024 0.0588 0.0002 0.0126 0.0109 0.0024 0.0014 0.001 0.0005
Cell Periphery 0.7454 0.9224 0.8814 0.9114 0.7735 0.9012 0.8177 0.9572 0.9417 0.8763 0.7713 0.9459 0.8318 0.9593 0.9388 0.8428 0.8891 0.9449
Cytoplasm 0.0025 0.0029 0.0024 0.001 0.0023 0.0008 0.0055 0.0031 0.0014 0.0013 0.0047 0.0048 0.005 0.0021 0.0026 0.002 0.0076 0.0018
Cytoplasmic Foci 0.0066 0 0.0051 0 0.0064 0 0.0127 0 0.0001 0.0038 0.0261 0.0002 0.0068 0 0.0006 0.0022 0.0183 0
Eisosomes 0.0103 0.004 0.0011 0.0002 0.0118 0.0038 0.0111 0.0065 0.0052 0.0009 0.0015 0.0003 0.0055 0.0008 0.0014 0.0036 0.0006 0.0003
Endoplasmic Reticulum 0.0057 0.0022 0.0023 0.0044 0.0375 0.0043 0.0062 0.0013 0.0017 0.0063 0.0097 0.0081 0.0055 0.0009 0.0028 0.0095 0.0038 0.0024
Endosome 0.0104 0 0.0014 0 0.0214 0 0.0068 0.0002 0 0.0118 0.0299 0.0009 0.0056 0 0.0007 0.0006 0.0077 0
Golgi 0.0069 0 0.0008 0 0.0033 0.0001 0.0064 0 0 0.0054 0.0021 0.0004 0.002 0 0.0004 0.0003 0.0007 0
Lipid Particles 0.0146 0.0004 0.0033 0.0005 0.0172 0.0008 0.0093 0.0001 0.0003 0.0052 0.0094 0.0002 0.0056 0.0001 0.0011 0.004 0.0056 0.0003
Mitochondria 0.0215 0.0001 0.0077 0.0001 0.0451 0.0096 0.0085 0.0005 0.0059 0.0234 0.0059 0.0001 0.0048 0 0.0031 0.0494 0.0003 0
None 0.0099 0.0001 0.0015 0 0.0043 0.0005 0.0024 0.0001 0.0003 0.0004 0.0025 0.0002 0.0084 0 0.0006 0.0037 0.0149 0
Nuclear Periphery 0.0068 0.0028 0.0028 0.0034 0.0139 0.0034 0.0047 0.002 0.0018 0.0084 0.0155 0.0015 0.0076 0.0018 0.003 0.006 0.0039 0.0016
Nucleolus 0.0117 0.0002 0.0018 0.0001 0.0049 0.0002 0.0007 0.0001 0.0034 0.0031 0.0036 0.0001 0.0054 0.0001 0.0009 0.0055 0.0003 0.0001
Nucleus 0.0037 0.0003 0.0008 0.0003 0.002 0.0003 0.0007 0.0004 0.0006 0.0014 0.0047 0.0002 0.0032 0.0003 0.0004 0.0015 0.0007 0.0003
Peroxisomes 0.0073 0 0.0096 0 0.0044 0.0001 0.0067 0 0.0004 0.0028 0.0097 0 0.0025 0 0.0011 0.0012 0.0004 0
Punctate Nuclear 0.0031 0 0.0014 0 0.0032 0 0.0012 0 0 0.0031 0.0022 0.0001 0.0049 0 0.0004 0.0001 0.0048 0
Vacuole 0.0798 0.0591 0.057 0.0763 0.0398 0.0699 0.0435 0.0185 0.0268 0.0333 0.0309 0.0311 0.0639 0.0232 0.0356 0.0575 0.0385 0.0428
Vacuole Periphery 0.002 0.0002 0.0008 0.0004 0.0018 0.0007 0.001 0.0006 0.0004 0.0012 0.0021 0.0003 0.001 0.0001 0.0003 0.0023 0.0006 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 48.4236 60.7973 76.5138 83.7091 75.8337 37.5211 29.3837 32.5278 29.2805 60.9477
Translational Efficiency 1.0346 1.1069 1.6098 1.0115 1.3797 0.946 0.8294 0.904 1.2251 1.1111

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
294 1268 226 279 1840 1533 2393 1710 2134 2801 2619 1989

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1753.38 3502.51 4058.62 2554.16 3347.11 3107.61 4210.48 3237.88 3127.54 3286.38 4197.38 3141.97
Standard Deviation 791.39 971.87 988.37 836.15 783.51 762.78 980.00 980.24 957.77 885.81 981.66 990.22
Intensity Change Log 2 — 0.998250 1.210851 0.542710 — -0.107111 0.331069 -0.047866 — 0.374041 0.697094 0.183436

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.013948 0.000612 0.000495 0.001804 0.000208 0.001065 0.000455 0.001227 0.002101 0.000860 0.000458 0.001308
Bud Neck 0.007152 0.000845 0.002285 0.001518 0.000157 0.000331 0.000337 0.000284 0.001120 0.000564 0.000505 0.000457
Bud Site 0.149633 0.010600 0.005019 0.027687 0.001502 0.005620 0.006410 0.004022 0.021910 0.007874 0.006290 0.007342
Cell Periphery 0.589437 0.940537 0.947916 0.918595 0.990838 0.982007 0.980230 0.986687 0.935537 0.963233 0.977442 0.977136
Cytoplasm 0.099023 0.017713 0.000213 0.018500 0.000128 0.000585 0.003171 0.000159 0.013752 0.008339 0.002916 0.002732
Cytoplasmic Foci 0.011169 0.000268 0.000155 0.000687 0.000037 0.000493 0.000069 0.000059 0.001571 0.000391 0.000076 0.000147
Eisosomes 0.005652 0.004356 0.013818 0.005469 0.002147 0.002044 0.001516 0.001993 0.002630 0.003091 0.002578 0.002481
Endoplasmic Reticulum 0.003698 0.000448 0.000198 0.000345 0.000608 0.000563 0.000166 0.000151 0.001034 0.000511 0.000169 0.000179
Endosome 0.006625 0.000248 0.000091 0.000265 0.000045 0.000342 0.000069 0.000331 0.000951 0.000299 0.000071 0.000321
Golgi 0.007009 0.001806 0.000376 0.000485 0.000119 0.000616 0.000237 0.000277 0.001068 0.001155 0.000249 0.000306
Lipid Particles 0.005598 0.001503 0.000015 0.007145 0.000015 0.000229 0.000035 0.000015 0.000784 0.000806 0.000033 0.001015
Mitochondria 0.001104 0.000279 0.001721 0.000198 0.000206 0.000446 0.000366 0.001233 0.000330 0.000371 0.000483 0.001088
Mitotic Spindle 0.000811 0.000308 0.000602 0.000276 0.000142 0.000430 0.000133 0.000149 0.000234 0.000375 0.000174 0.000167
None 0.000043 0.000082 0.000049 0.000018 0.000008 0.000041 0.000041 0.000012 0.000013 0.000059 0.000042 0.000013
Nuclear Periphery 0.000190 0.000302 0.000459 0.000206 0.000213 0.000307 0.000330 0.000111 0.000210 0.000305 0.000341 0.000125
Nuclear Periphery Foci 0.000765 0.000457 0.000073 0.000111 0.000114 0.000168 0.000025 0.000015 0.000204 0.000299 0.000029 0.000028
Nucleolus 0.000042 0.000081 0.000157 0.000028 0.000042 0.000050 0.000046 0.000034 0.000042 0.000064 0.000056 0.000033
Nucleus 0.005579 0.000437 0.000250 0.000379 0.000050 0.000113 0.000205 0.000077 0.000811 0.000259 0.000209 0.000119
Peroxisomes 0.000462 0.000024 0.000003 0.000128 0.000002 0.000027 0.000016 0.000004 0.000065 0.000026 0.000015 0.000022
Vacuole 0.087991 0.015248 0.022414 0.015258 0.002221 0.002952 0.004351 0.001797 0.014038 0.008518 0.005910 0.003686
Vacuole Periphery 0.004068 0.003847 0.003692 0.000900 0.001199 0.001570 0.001791 0.001361 0.001594 0.002601 0.001955 0.001296

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 5.38 5.43 4.78 -2.07 -2.27 -1.92 -1.86 -2.48 -0.12 -1.84 2.67 4.34 1.60 -0.91 -2.30
Bud Neck 6.02 4.26 5.16 -2.23 1.32 -3.58 -2.09 -2.62 0.88 0.66 3.39 3.39 4.01 1.38 0.50
Bud Site 9.61 10.01 7.75 -2.63 -3.50 -3.09 -4.22 -2.52 1.21 1.83 5.61 6.33 5.70 0.37 -0.73
Cell Periphery -14.92 -15.14 -12.49 1.89 2.41 3.64 5.34 1.75 -1.89 -2.82 -5.79 -9.07 -8.34 -4.14 0.24
Cytoplasm 7.70 9.51 6.76 -0.22 -3.11 -0.22 -3.59 0.79 2.52 5.15 3.06 6.46 6.14 3.96 0.16
Cytoplasmic Foci 3.92 3.96 3.73 -0.98 -1.23 -1.62 -1.46 -0.41 1.58 0.45 2.89 3.84 3.62 1.44 -1.11
Eisosomes 0.76 -2.85 0.04 -0.96 3.06 0.29 1.92 0.46 0.18 -1.95 -1.09 0.08 0.36 1.63 0.29
Endoplasmic Reticulum 2.93 3.16 3.03 0.97 -2.19 0.11 1.18 1.22 2.62 0.46 1.40 2.40 2.38 3.48 -0.28
Endosome 3.22 3.30 3.20 -0.11 -1.13 -2.41 -2.42 -1.72 0.14 -1.57 2.20 3.17 1.98 -0.08 -1.73
Golgi 1.51 1.96 1.93 3.46 -0.66 -1.96 -6.08 -1.48 1.24 -0.37 -0.26 1.74 1.58 3.69 -0.60
Lipid Particles 2.50 3.50 -0.40 -1.39 -1.76 -1.59 -1.29 0.05 1.60 2.35 -0.18 3.36 -0.42 -0.35 -1.72
Mitochondria 1.72 -0.64 1.89 1.59 1.82 -2.15 -1.67 -2.09 -1.53 -1.73 -0.52 -1.21 -1.78 -1.67 -1.38
Mitotic Spindle 1.01 0.40 1.08 0.93 4.61 -1.95 0.88 -0.15 1.90 -0.53 -1.44 0.89 0.95 2.42 0.30
None -1.62 0.02 2.71 3.59 2.67 -1.76 -1.81 -1.54 1.56 1.59 -3.45 -1.67 0.30 3.51 1.72
Nuclear Periphery -4.50 -6.44 -0.51 3.49 5.83 -1.41 -1.76 1.56 12.55 14.28 -1.66 -2.28 1.51 15.29 14.80
Nuclear Periphery Foci 2.05 5.39 4.94 2.40 -1.68 -0.49 0.95 1.05 1.55 2.65 -0.75 2.24 2.22 3.23 -0.23
Nucleolus -3.07 -4.86 1.30 10.45 6.29 -1.58 -1.03 2.09 2.85 2.95 -4.92 -3.07 2.45 7.24 5.43
Nucleus 2.44 2.52 2.42 -0.16 -1.49 -2.14 -4.04 -0.82 1.18 3.11 1.92 2.08 2.34 2.72 1.88
Peroxisomes 5.16 5.41 2.87 -1.34 -1.60 -2.00 -6.78 -1.08 1.80 3.57 2.47 4.06 2.60 0.46 -0.60
Vacuole 6.59 5.94 6.11 -0.40 1.08 -2.54 -5.88 1.64 3.62 6.61 3.42 4.96 5.80 5.18 2.66
Vacuole Periphery 0.07 0.15 1.65 9.61 6.46 -3.27 -5.22 -0.66 0.79 1.61 -3.41 -1.34 0.83 5.07 2.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; not an essential gene; YLR413W has a paralog, FAT3, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (77%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-1

Ina1

Ina1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ina1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available