Standard name
Human Ortholog
Description Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.1 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0.07 0 0.06 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.53 0.82 0.79 0.78 0.76 0.71 0.67 0.65 0.54 – 0.46 0.53 0.93 0.95 0.95 0.74 0.72 0.78 0.34 0.58 0.38 0.68 0.68 0.65
Endoplasmic Reticulum 0.08 0.11 0.07 0 0 0.05 0 0 0.05 – 0.05 0 0 0 0 0.05 0 0.05 0.05 0 0.05 0 0.06 0.1
Endosome 0.16 0 0.08 0.05 0.1 0 0.05 0.06 0 – 0 0 0.05 0 0 0.07 0.08 0.06 0.26 0.13 0.12 0.05 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0
Mitochondria 0 0 0 0.26 0.18 0.35 0.39 0.36 0.59 – 0.62 0.62 0.05 0 0.05 0 0 0 0.1 0.08 0.22 0.07 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.06 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.09 0.1 0.07 0 0.06 0.11 0.07 0.06 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 33 10 9 0 3 2 1 6 7 – 4 1 0 0 0 18 21 21 17 10 15 4 3 6
Bud 1 3 8 11 8 7 11 18 10 – 13 12 7 3 8 3 2 3 4 4 4 3 3 5
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 8 8 4 1 3 3
Bud Site 0 0 0 0 1 0 1 3 1 – 2 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 6 3 1 5 3 4 4 6 10 – 6 12 2 1 2 8 11 2 1 1 1 0 0 0
Cytoplasm 177 244 211 206 254 266 322 342 224 – 87 172 116 204 235 373 344 361 159 220 149 116 143 123
Endoplasmic Reticulum 25 32 18 2 5 19 6 5 21 – 10 4 0 2 6 27 18 23 23 15 18 5 11 19
Endosome 53 11 22 14 35 14 22 30 2 – 0 4 6 4 1 37 38 26 120 51 45 8 8 6
Golgi 3 1 0 0 0 0 0 0 1 – 0 0 0 0 0 1 2 2 33 5 8 0 1 2
Mitochondria 9 4 9 69 60 132 190 188 242 – 117 202 6 5 13 18 11 17 47 29 83 12 12 7
Nucleus 13 0 0 0 0 0 0 3 2 – 4 2 0 0 0 32 24 14 2 0 1 0 0 0
Nuclear Periphery 9 1 0 0 0 1 0 1 0 – 0 0 0 0 0 0 0 1 1 0 1 0 0 1
Nucleolus 3 0 0 0 1 0 0 1 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 0 0 0 – 0 1 0 0 0 0 0 0 4 0 2 0 0 0
SpindlePole 12 1 5 1 3 0 4 8 0 – 2 0 0 0 0 7 8 5 15 5 3 1 2 1
Vac/Vac Membrane 22 3 4 3 10 3 6 20 3 – 2 7 3 3 3 43 48 32 19 21 42 12 13 6
Unique Cell Count 331 296 268 264 334 377 482 529 412 189 324 125 214 247 505 475 462 464 380 389 171 211 190
Labelled Cell Count 366 313 287 311 384 448 567 631 523 247 417 140 222 268 569 527 507 464 380 389 171 211 190


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 6.6 5.5 5.2 5.3 5.1 5.0 5.1 4.6 – 4.7 4.5 6.1 6.9 6.3 7.8 8.9 8.6 6.6 6.6 7.4
Std Deviation (1e-4) 0.9 0.7 0.8 1.4 1.4 1.1 1.3 1.3 1.2 – 1.4 1.4 2.0 2.3 1.9 1.4 1.5 1.6 1.8 1.5 2.3
Intensity Change (Log2) – – – -0.07 -0.05 -0.11 -0.14 -0.11 -0.27 – -0.21 -0.28 0.16 0.33 0.19 0.51 0.7 0.65 0.27 0.26 0.43

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 -2.1 0 0 -2.2 0 – 0 0 0 0 0 0.1 0.7 0.8
Bud 0.7 -0.4 -0.9 -0.6 0.3 0 – 0 0 0 0 0.2 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm -0.2 -0.8 -2.3 -3.5 -4.1 -6.5 – -7.2 -6.5 3.5 5.2 5.5 -1.5 -1.9 -0.2
Endoplasmic Reticulum -3.6 -3.3 -0.9 -4.1 -4.6 0 – 0 0 -3.0 -3.2 -2.3 -0.8 -1.8 -1.0
Endosome -1.3 0.9 -2.5 -2.0 -1.4 0 – 0 0 -1.2 -3.1 -4.3 -0.4 -0.1 -1.4
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 7.4 5.6 9.6 10.7 9.9 0 – 0 0 0 -0.7 1.1 0.1 -0.8 0.2
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 4.2 3.7 2.9
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 1.2 0 0 1.8 0 – 0 0 0 0 0 3.9 4.4 3.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.0768 6.6648 6.1776 5.8582 5.3169 6.1252 3.7331 5.0926 4.9803 4.5454 4.4567 4.5194 4.5282 4.9382 4.1024 5.1076 5.4977 4.7192
Actin 0.0069 0.0079 0.0147 0.0046 0.0041 0.0054 0.0353 0.0016 0.0165 0.0081 0.0098 0.0117 0.0034 0.0063 0.0109 0.0223 0.0204 0.0025
Bud 0.0005 0.0005 0.0014 0.0006 0.0004 0.0004 0.0009 0.0007 0.0027 0.0003 0.0007 0.0008 0.0001 0.0002 0.0031 0.001 0.0003 0.0002
Bud Neck 0.0057 0.0024 0.0016 0.0011 0.0303 0.0114 0.0024 0.0005 0.0027 0.0005 0.0021 0.0034 0.0014 0.0003 0.0011 0.0012 0.0225 0.0016
Bud Periphery 0.0005 0.0003 0.0011 0.0007 0.0002 0.001 0.0008 0.0004 0.0024 0.0001 0.0008 0.0008 0 0.0001 0.0021 0.0009 0.0002 0.0001
Bud Site 0.0034 0.0161 0.0046 0.0013 0.0009 0.0009 0.0035 0.0123 0.0096 0.0007 0.0014 0.0008 0.0014 0.0016 0.0052 0.0023 0.0008 0.0004
Cell Periphery 0.0019 0.0019 0.0014 0.0005 0.0005 0.0022 0.0004 0.0005 0.0003 0.0001 0.0002 0.0001 0.0003 0.0004 0.0004 0.0003 0.0001 0.0002
Cytoplasm 0.5033 0.6285 0.5307 0.5558 0.5035 0.6338 0.3772 0.6605 0.5679 0.594 0.5035 0.6732 0.4329 0.5501 0.5045 0.3543 0.4918 0.6257
Cytoplasmic Foci 0.1251 0.1267 0.1521 0.1094 0.1893 0.1217 0.1113 0.1077 0.1056 0.1529 0.116 0.1209 0.1522 0.1565 0.1683 0.1186 0.1463 0.1449
Eisosomes 0.0002 0.0001 0.0002 0 0 0.0003 0.0004 0.0001 0.0002 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0421 0.0209 0.0173 0.0107 0.0063 0.0212 0.0171 0.0089 0.012 0.0069 0.0242 0.0149 0.0157 0.0094 0.0151 0.0183 0.0054 0.0163
Endosome 0.1817 0.1138 0.1789 0.2344 0.1946 0.1402 0.2025 0.1102 0.1351 0.1888 0.2086 0.1019 0.1255 0.1045 0.1862 0.2076 0.072 0.1205
Golgi 0.0222 0.0291 0.0388 0.0319 0.0368 0.0313 0.0453 0.0093 0.019 0.0225 0.0447 0.0158 0.047 0.0139 0.0277 0.0501 0.0316 0.0254
Lipid Particles 0.0155 0.0042 0.0063 0.0026 0.0039 0.0027 0.0355 0.0027 0.007 0.0011 0.0045 0.0065 0.0125 0.002 0.0072 0.0025 0.0019 0.0019
Mitochondria 0.0025 0.0017 0.005 0.0023 0.0018 0.0059 0.0132 0.0062 0.0171 0.0019 0.0528 0.0029 0.0011 0.0005 0.0058 0.0099 0.0011 0.0017
None 0.0662 0.0315 0.0297 0.0037 0.0101 0.0068 0.0884 0.0689 0.0785 0.0131 0.0057 0.0319 0.201 0.1338 0.0452 0.2 0.1917 0.049
Nuclear Periphery 0.0023 0.001 0.001 0.0017 0.0008 0.0008 0.0128 0.0008 0.0024 0.001 0.0014 0.0012 0.0008 0.0005 0.0018 0.0012 0.0009 0.0006
Nucleolus 0.0002 0.0001 0.0001 0.0001 0 0.0002 0.0009 0.0001 0.0004 0 0.0001 0.0004 0 0 0.0006 0 0.0002 0.0001
Nucleus 0.0011 0.001 0.0008 0.0015 0.0007 0.0009 0.0024 0.0009 0.0012 0.0006 0.0007 0.0023 0.0002 0.0004 0.0009 0.0004 0.0006 0.0005
Peroxisomes 0.0041 0.0045 0.0052 0.009 0.0045 0.0064 0.0147 0.0021 0.009 0.0018 0.0104 0.0038 0.0032 0.0151 0.0062 0.0036 0.0078 0.0022
Punctate Nuclear 0.0012 0.0006 0.0011 0.0005 0.0006 0.0004 0.0094 0.0008 0.0023 0.0005 0.0003 0.0024 0.0006 0.0005 0.0018 0.0005 0.0013 0.0016
Vacuole 0.0122 0.0062 0.0066 0.0247 0.0086 0.0048 0.0205 0.0042 0.0062 0.0039 0.0096 0.0031 0.0005 0.0032 0.0045 0.0036 0.0024 0.0037
Vacuole Periphery 0.0013 0.0009 0.0016 0.0029 0.002 0.0014 0.0053 0.0007 0.0017 0.0014 0.0025 0.0011 0.0003 0.0006 0.0013 0.0013 0.0005 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.6257 14.1832 8.8023 19.6189 15.3347 15.5689 24.4442 23.5814 16.9942 26.2102
Translational Efficiency 0.3057 0.4369 0.5017 0.2226 0.3546 0.4187 0.2965 0.2688 0.3331 0.2302

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1874 924 618 1428 1854 2305 122 1372 3728 3229 740 2800

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 783.62 821.54 1140.40 973.54 731.54 831.27 1069.56 962.75 757.72 828.49 1128.72 968.25
Standard Deviation 92.38 128.21 141.23 119.66 110.05 105.40 113.18 119.81 104.84 112.49 139.50 119.85
Intensity Change Log 2 — 0.068177 0.541314 0.313086 — 0.184380 0.548009 0.396224 — 0.125451 0.544550 0.353825

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001322 0.001632 0.013596 0.004225 0.001147 0.001424 0.007832 0.010751 0.001235 0.001483 0.012646 0.007423
Bud Neck 0.012059 0.009218 0.004156 0.007929 0.011427 0.012176 0.006475 0.006241 0.011744 0.011330 0.004539 0.007102
Bud Site 0.019748 0.019688 0.059133 0.048779 0.016711 0.026922 0.033925 0.045955 0.018238 0.024852 0.054977 0.047395
Cell Periphery 0.000132 0.000123 0.000225 0.000070 0.000098 0.000079 0.000148 0.000097 0.000115 0.000092 0.000212 0.000083
Cytoplasm 0.122973 0.141087 0.180593 0.268192 0.170753 0.199106 0.085646 0.203630 0.146734 0.182503 0.164940 0.236556
Cytoplasmic Foci 0.473645 0.481443 0.351015 0.250210 0.484264 0.448017 0.299559 0.344821 0.478926 0.457582 0.342532 0.296570
Eisosomes 0.000263 0.000140 0.000059 0.000046 0.000298 0.000180 0.000122 0.000099 0.000280 0.000168 0.000069 0.000072
Endoplasmic Reticulum 0.001368 0.001398 0.003919 0.000508 0.001799 0.000798 0.001911 0.000738 0.001582 0.000969 0.003588 0.000621
Endosome 0.101581 0.146464 0.094383 0.096710 0.102600 0.093483 0.210697 0.101049 0.102088 0.108644 0.113559 0.098836
Golgi 0.179600 0.088073 0.050302 0.010596 0.099067 0.112697 0.011713 0.016436 0.139549 0.105651 0.043940 0.013458
Lipid Particles 0.012275 0.011639 0.015869 0.004206 0.019249 0.005730 0.025393 0.008280 0.015743 0.007421 0.017439 0.006202
Mitochondria 0.019685 0.009904 0.000186 0.002149 0.016124 0.014502 0.000165 0.001552 0.017914 0.013186 0.000183 0.001856
Mitotic Spindle 0.005996 0.009362 0.121836 0.052454 0.004194 0.010982 0.025276 0.025992 0.005100 0.010519 0.105917 0.039488
None 0.000373 0.000636 0.000169 0.000272 0.001405 0.000252 0.000060 0.000123 0.000886 0.000362 0.000151 0.000199
Nuclear Periphery 0.000061 0.000147 0.000312 0.000291 0.000289 0.000082 0.000346 0.000129 0.000174 0.000100 0.000318 0.000211
Nuclear Periphery Foci 0.000300 0.000794 0.009907 0.001126 0.000977 0.000187 0.009271 0.001174 0.000636 0.000361 0.009802 0.001149
Nucleolus 0.000299 0.000638 0.000093 0.000335 0.001479 0.000335 0.000524 0.000127 0.000886 0.000421 0.000164 0.000233
Nucleus 0.003177 0.003759 0.004554 0.005786 0.007836 0.002930 0.004512 0.003820 0.005494 0.003167 0.004547 0.004823
Peroxisomes 0.020070 0.017391 0.009831 0.042455 0.014138 0.018990 0.053149 0.067113 0.017120 0.018533 0.016973 0.054537
Vacuole 0.018616 0.047900 0.077156 0.201619 0.039777 0.045172 0.217675 0.160651 0.029140 0.045953 0.100323 0.181545
Vacuole Periphery 0.006458 0.008563 0.002705 0.002044 0.006368 0.005957 0.005602 0.001223 0.006413 0.006703 0.003183 0.001642

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.74 -5.41 -3.23 -1.99 4.64 -0.75 -2.18 -6.21 -6.14 -0.40 -1.02 -5.81 -6.93 -6.57 3.26
Bud Neck 2.42 7.92 4.37 1.74 -6.16 -0.81 3.93 7.45 9.35 0.84 0.62 10.94 7.85 8.31 -5.12
Bud Site 0.05 -10.71 -6.58 -6.25 5.57 -5.67 -2.57 -9.52 -5.19 -1.15 -4.86 -11.41 -11.38 -7.06 4.66
Cell Periphery 0.26 -3.84 5.02 2.68 8.45 1.78 -2.73 0.91 -1.24 3.55 1.96 -5.23 4.65 2.21 8.32
Cytoplasm -2.41 -6.07 -19.43 -15.33 -8.19 -4.10 5.21 -6.23 -2.85 -8.46 -6.99 -2.91 -18.27 -11.67 -8.32
Cytoplasmic Foci -0.89 14.12 39.97 32.94 13.83 5.44 11.67 23.36 19.15 -1.51 4.24 18.05 43.58 37.37 8.74
Eisosomes 4.73 11.36 13.05 5.14 3.33 1.91 2.90 3.54 5.70 2.92 3.37 6.79 7.09 8.34 1.23
Endoplasmic Reticulum -0.08 -5.38 3.57 3.65 8.30 3.53 -0.85 5.11 0.61 4.56 2.75 -5.38 6.05 2.49 8.68
Endosome -7.35 2.17 8.88 13.61 4.85 2.42 -4.51 4.42 2.65 5.56 -2.06 -0.68 9.38 11.09 5.99
Golgi 15.41 24.00 38.80 19.79 11.31 -3.16 19.25 26.90 30.86 -0.69 9.13 24.53 45.91 37.19 10.23
Lipid Particles 0.41 -3.29 8.98 6.45 10.57 9.99 -0.88 8.06 -3.12 2.62 9.33 -1.58 11.62 2.58 8.20
Mitochondria 5.47 15.68 14.20 6.43 -3.00 1.11 13.70 12.10 13.92 -2.63 4.25 20.80 18.63 15.50 -3.96
Mitotic Spindle -1.87 -13.57 -10.64 -9.29 7.71 -5.56 -2.83 -7.76 -5.03 0.64 -5.21 -13.79 -13.12 -10.44 8.88
None -1.22 1.93 0.17 1.34 -2.27 3.54 3.96 3.89 2.43 -0.39 2.89 4.15 3.76 1.64 -1.39
Nuclear Periphery -2.82 -6.36 -14.38 -9.43 -2.06 2.85 -2.30 1.14 -6.01 3.28 1.92 -4.31 -4.73 -12.26 1.40
Nuclear Periphery Foci -3.12 -6.91 -8.38 -3.94 6.18 3.66 -2.89 -2.24 -8.74 2.79 2.15 -7.23 -6.15 -10.62 6.70
Nucleolus -2.62 2.49 -1.98 1.60 -9.01 4.19 3.11 5.07 1.65 3.67 3.08 5.08 4.25 1.32 -3.93
Nucleus -0.74 -2.57 -8.12 -7.71 -4.66 5.25 1.23 2.28 -4.33 0.44 3.89 -0.24 -3.55 -9.68 -2.84
Peroxisomes 1.58 6.90 -4.07 -5.03 -8.78 -3.85 -4.03 -13.15 -11.33 -0.66 -1.36 0.68 -12.81 -11.78 -10.32
Vacuole -9.22 -12.94 -39.16 -32.67 -23.14 -2.25 -9.64 -27.83 -26.85 0.88 -9.17 -14.08 -47.20 -42.59 -18.70
Vacuole Periphery -2.65 7.66 10.67 10.54 3.66 0.85 0.53 13.85 14.74 1.15 -0.71 5.51 16.91 17.53 3.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm
Localization
Cell Percentages cytoplasm (27%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-3

Ecm30

Ecm30


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ecm30-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available