Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L6B; binds 5.8S rRNA; homologous to mammalian ribosomal protein L6, no bacterial homolog; RPL6B has a paralog, RPL6A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0.08 0.06 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.97 0.98 0.98 0.93 0.93 0.83 0.81 0.75 0.7 0.78 0.73 0.99 0.99 0.99 0.99 0.97 0.98 0.96 0.9 0.93 0.91 0.9 0.89
Endoplasmic Reticulum 0 0 0 0 0.05 0.09 0.17 0.17 0.2 0.2 0.13 0.18 0 0 0 0 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0.05 0 0.06 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 2 0 2 4 11 13 7 16 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 1 0 0 0 1 0 1 1 0 0 0 1 1 0 1 4 0 2 4 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 3 1 1 4 5 12 15 9 33 19 27 5 3 4 2 3 2 0 0 0 0 2 3
Cytoplasm 285 403 314 181 227 288 268 295 249 297 241 251 335 387 431 250 335 246 271 383 280 280 340 324
Endoplasmic Reticulum 1 7 11 2 13 29 54 61 67 86 40 61 6 7 7 6 23 10 4 8 12 12 12 12
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Golgi 0 1 1 0 2 0 4 17 11 26 18 18 0 0 0 0 5 2 0 0 0 0 0 0
Mitochondria 0 1 0 0 1 0 1 1 9 6 7 9 0 0 0 4 2 0 0 2 0 1 0 2
Nucleus 0 1 0 0 0 0 2 0 0 1 0 1 0 0 0 0 0 0 0 4 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1
Nucleolus 0 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 3 3 0 1 0 0 3 2 4 3 2 3 0 1 0 0 4 1 2 16 3 2 7 9
Unique Cell Count 289 416 320 184 243 309 322 366 331 422 308 342 340 392 434 252 344 251 283 428 303 308 377 363
Labelled Cell Count 289 421 327 185 250 322 346 395 361 467 335 387 346 398 442 265 373 261 283 428 303 308 377 363


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 86.9 50.3 68.9 60.8 41.3 39.4 33.6 30.4 28.0 29.4 26.2 27.2 74.6 64.8 60.0 68.9 89.2 95.7 70.1 75.6 75.0
Std Deviation (1e-4) 16.6 15.2 13.8 14.7 11.7 7.2 7.2 5.6 6.4 6.7 6.3 6.6 14.7 14.5 11.9 23.0 25.3 30.4 19.9 23.1 22.8
Intensity Change (Log2) – – – -0.18 -0.74 -0.8 -1.04 -1.18 -1.3 -1.23 -1.4 -1.34 0.11 -0.09 -0.2 0.0 0.37 0.47 0.03 0.13 0.12


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 3.3 3.2 0 3.9 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 3.1 3.3 0 4.8 4.2 4.8 0 0 0 0 0 0
Cytoplasm 0.2 -2.9 -3.0 -6.5 -7.3 -8.5 -9.8 -7.8 -9.0 0.4 0.6 1.5 1.1 -0.6 -0.1
Endoplasmic Reticulum 0 1.1 3.1 5.6 5.6 6.6 6.8 4.4 5.9 -1.4 -1.4 -1.6 -0.7 1.9 0.3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 3.5 2.9 4.2 4.0 3.8 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 72.7715 97.4378 85.7235 75.2683 77.1775 81.585 76.1564 97.4524 92.515 91.0203 67.9133 87.3808 71.6281 94.3019 87.8864 83.4251 74.3829 88.7935
Actin 0.0066 0.0004 0.0035 0.0009 0.0577 0.0071 0.0024 0.0006 0.0041 0.0021 0.0012 0.0037 0.0087 0.0002 0.003 0.0009 0.0012 0.0021
Bud 0.0025 0.0005 0.0031 0.0059 0.0022 0.0012 0.0031 0.0008 0.0049 0.0124 0.0045 0.0019 0.0015 0.0004 0.0008 0.0019 0.0011 0.0018
Bud Neck 0.0022 0.0009 0.0015 0.0009 0.0028 0.0011 0.001 0.0007 0.0014 0.0019 0.001 0.004 0.0005 0.0004 0.0007 0.0009 0.0009 0.0014
Bud Periphery 0.0035 0.0003 0.0058 0.0088 0.0014 0.0012 0.0024 0.0004 0.0028 0.0147 0.0015 0.0021 0.0012 0.0005 0.0007 0.0007 0.0005 0.0035
Bud Site 0.0032 0.0004 0.0027 0.0008 0.0031 0.0005 0.0014 0.0004 0.0024 0.0015 0.0008 0.0004 0.0006 0.0002 0.0004 0.0003 0.0007 0.0003
Cell Periphery 0.0227 0.0091 0.0193 0.0121 0.0067 0.0025 0.0199 0.0025 0.006 0.0154 0.0013 0.0066 0.006 0.0031 0.0093 0.0065 0.0045 0.0049
Cytoplasm 0.5228 0.8626 0.7203 0.6091 0.675 0.5449 0.7245 0.9283 0.8491 0.7038 0.7973 0.6824 0.7361 0.9437 0.8492 0.7646 0.7445 0.8469
Cytoplasmic Foci 0.0137 0.0016 0.0106 0.002 0.0072 0.0069 0.0045 0.0019 0.0046 0.0026 0.0097 0.0087 0.0143 0.001 0.0044 0.0035 0.0167 0.0028
Eisosomes 0.0004 0 0.0002 0 0.0002 0.0003 0.0001 0 0 0 0 0 0.0002 0 0.0001 0 0.0011 0.0001
Endoplasmic Reticulum 0.1219 0.0358 0.028 0.0082 0.0295 0.157 0.0616 0.0095 0.0167 0.0072 0.0065 0.0544 0.0605 0.0113 0.0196 0.0181 0.0106 0.0456
Endosome 0.0149 0.006 0.0101 0.0107 0.0264 0.0397 0.0137 0.0077 0.0105 0.0078 0.0239 0.028 0.0139 0.0023 0.0144 0.0116 0.0252 0.0166
Golgi 0.0034 0.0009 0.002 0.0005 0.0116 0.0305 0.0026 0.0009 0.0025 0.0005 0.0009 0.0052 0.0017 0.0003 0.0017 0.0005 0.0018 0.005
Lipid Particles 0.0032 0.0006 0.0036 0.0007 0.0024 0.0008 0.0021 0.0001 0.0012 0.0005 0.0013 0.0018 0.0028 0.0004 0.0022 0.0019 0.0086 0.0004
Mitochondria 0.0101 0.0004 0.0153 0.0031 0.0033 0.1308 0.0047 0.0011 0.0016 0.0011 0.0013 0.0069 0.005 0.0004 0.004 0.0007 0.0276 0.0189
None 0.0036 0.0001 0.0016 0.001 0.0005 0.0007 0.0017 0.0001 0.0009 0.0004 0.0039 0.0014 0.0063 0.0001 0.0029 0.0033 0.0177 0.0005
Nuclear Periphery 0.0679 0.0058 0.0136 0.0099 0.0086 0.0191 0.0374 0.0023 0.004 0.0197 0.01 0.0274 0.018 0.0027 0.0064 0.0062 0.008 0.0091
Nucleolus 0.0024 0 0.0008 0.0021 0.0004 0.0002 0.0009 0 0.0005 0.0005 0.0005 0.0027 0.0044 0 0.0016 0.0012 0.0132 0.0004
Nucleus 0.0124 0.0017 0.0062 0.0092 0.0043 0.0023 0.0125 0.0013 0.0034 0.0086 0.0066 0.0237 0.0074 0.0012 0.007 0.0046 0.0102 0.0032
Peroxisomes 0.0028 0 0.0004 0.0001 0.0006 0.0002 0.0003 0 0.0002 0.0002 0.0003 0.0002 0.0005 0 0.0007 0.0001 0.001 0.0001
Punctate Nuclear 0.0035 0 0.0004 0.0001 0.0004 0.0002 0.0008 0 0.0001 0.0001 0.0005 0.0262 0.0077 0 0.0022 0.0001 0.0025 0.0001
Vacuole 0.1346 0.0658 0.121 0.2349 0.1318 0.0399 0.0869 0.0354 0.0686 0.1494 0.1 0.0735 0.0835 0.0274 0.0577 0.1296 0.073 0.0249
Vacuole Periphery 0.0416 0.007 0.03 0.079 0.0239 0.0129 0.0156 0.0057 0.0146 0.0495 0.0269 0.0387 0.0193 0.0044 0.011 0.0428 0.0293 0.0116

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1452.5042 1701.5453 1943.5527 1492.1945 1825.3102 1690.5348 1472.978 1270.1934 1488.5103 1325.8163
Translational Efficiency 1.9864 1.7072 1.5811 1.8484 1.7652 1.6901 1.6255 1.9899 1.6009 1.9106

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1981 669 2729 2364 958 2499 300 1304 2939 3168 3029 3668

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3885.56 5217.94 7768.38 4606.80 3594.03 5186.07 6508.20 5300.96 3790.53 5192.80 7643.57 4853.58
Standard Deviation 967.74 1106.36 1391.08 1741.68 823.41 1057.95 1318.11 1962.42 933.23 1068.43 1434.30 1853.25
Intensity Change Log 2 — 0.425358 0.999491 0.245642 — 0.529039 0.856656 0.560651 — 0.476109 0.932619 0.405600

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000037 0.000104 0.000086 0.000158 0.000104 0.000075 0.000229 0.000339 0.000059 0.000081 0.000101 0.000222
Bud Neck 0.000176 0.000638 0.000505 0.002133 0.000390 0.000312 0.006739 0.002107 0.000245 0.000381 0.001122 0.002124
Bud Site 0.002300 0.003556 0.002286 0.013749 0.002217 0.004446 0.005667 0.016112 0.002273 0.004258 0.002621 0.014589
Cell Periphery 0.022426 0.068072 0.044208 0.013273 0.042871 0.017544 0.050025 0.036741 0.029090 0.028214 0.044784 0.021616
Cytoplasm 0.585325* 0.303995* 0.559524* 0.625913* 0.353604* 0.604614* 0.185595* 0.464508* 0.509793* 0.541131* 0.522489* 0.568532*
Cytoplasmic Foci 0.010369 0.011238 0.005694 0.005802 0.008141 0.018759 0.011126 0.011383 0.009643 0.017170 0.006232 0.007786
Eisosomes 0.000001 0.000004 0.000003 0.000003 0.000002 0.000002 0.000014 0.000006 0.000002 0.000002 0.000004 0.000004
Endoplasmic Reticulum 0.003465 0.003970 0.004695 0.001020 0.004547 0.004841 0.000660 0.001549 0.003817 0.004657 0.004295 0.001208
Endosome 0.001103 0.001769 0.000732 0.002347 0.001511 0.001754 0.001321 0.001831 0.001236 0.001757 0.000790 0.002164
Golgi 0.039342 0.124269* 0.033771 0.011203 0.129694* 0.082785 0.053794 0.042787 0.068793 0.091545 0.035754 0.022431
Lipid Particles 0.019837 0.046610 0.029071 0.009581 0.029961 0.022444 0.038442 0.027188 0.023137 0.027547 0.029999 0.015841
Mitochondria 0.000270 0.000218 0.000352 0.000549 0.000187 0.000454 0.000154 0.000884 0.000243 0.000404 0.000333 0.000668
Mitotic Spindle 0.000382 0.001035 0.000783 0.004135 0.000716 0.001069 0.003071 0.002580 0.000491 0.001062 0.001009 0.003582
None 0.001044 0.001031 0.000968 0.001504 0.001324 0.001091 0.000623 0.002512 0.001135 0.001078 0.000934 0.001862
Nuclear Periphery 0.000365 0.001150 0.001008 0.000397 0.000963 0.000460 0.003313 0.000655 0.000560 0.000605 0.001237 0.000489
Nuclear Periphery Foci 0.008507 0.016426 0.009552 0.004175 0.021552 0.010739 0.022059 0.009310 0.012759 0.011940 0.010790 0.006001
Nucleolus 0.000134 0.000144 0.000092 0.000438 0.000148 0.000063 0.000153 0.000197 0.000139 0.000080 0.000098 0.000352
Nucleus 0.002442 0.001715 0.002540 0.022416 0.002822 0.001431 0.010495 0.014764 0.002566 0.001491 0.003328 0.019696
Peroxisomes 0.000168 0.000070 0.000193 0.000254 0.000043 0.000080 0.000022 0.000100 0.000127 0.000078 0.000176 0.000199
Vacuole 0.166407 0.242523* 0.213500* 0.236713* 0.196703 0.113790 0.510850* 0.294150* 0.176283 0.140975 0.242951* 0.257132*
Vacuole Periphery 0.135901* 0.171461* 0.090437 0.044238 0.202499* 0.113248* 0.095648 0.070297 0.157609* 0.125542* 0.090953 0.053502

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.35 -8.12 -7.47 -2.63 -4.31 0.96 -3.40 -4.04 -5.37 -1.20 -1.75 -4.01 -7.38 -6.88 -5.64
Bud Neck -4.99 -7.04 -13.02 -10.33 -11.02 1.26 -7.63 -10.82 -11.11 5.21 -4.31 -8.96 -16.63 -15.61 -8.17
Bud Site -3.47 -0.49 -14.25 -11.93 -13.99 -3.92 -4.13 -9.50 -7.73 -5.82 -4.81 -2.15 -16.82 -12.69 -15.89
Cell Periphery -12.48 -11.63 8.03 16.27 20.24 9.70 -0.85 3.80 -7.07 3.52 0.55 -8.62 7.82 7.87 16.79
Cytoplasm 19.28 3.21 -3.33 -22.40 -7.09 -19.38 8.88 -8.63 10.17 -16.19 -3.29 -0.76 -6.95 -3.50 -6.20
Cytoplasmic Foci -0.64 5.94 4.72 3.76 -1.51 -9.86 -3.08 -4.27 2.36 -0.66 -8.32 5.12 0.25 8.28 -4.50
Eisosomes -7.04 -9.74 -3.56 0.18 -1.39 2.04 -6.05 -4.56 -5.16 3.64 -4.77 -8.93 -5.64 -4.28 -1.39
Endoplasmic Reticulum -0.88 -2.68 9.48 6.06 10.65 -0.39 5.67 4.52 8.28 -2.89 -2.01 -0.96 9.36 11.21 9.93
Endosome -4.94 6.35 -3.77 -1.44 -4.98 -2.31 1.24 -1.44 -0.06 -2.20 -7.01 8.57 -4.08 -1.51 -6.24
Golgi -16.07 3.00 18.76 22.68 21.38* 9.02 14.63 18.67 14.98 3.46 -7.74 15.16 23.42 31.22 12.99
Lipid Particles -8.75 -6.10 8.84 13.23 17.95 3.52 -2.59 2.23 -1.29 4.54 -3.13 -5.09 7.59 11.10 13.98
Mitochondria 0.40 -2.82 -4.89 -3.99 -3.63 -4.85 -0.07 -2.50 -1.54 -2.49 -3.97 -3.63 -4.25 -2.57 -3.34
Mitotic Spindle -6.29 -2.65 -7.42 -6.75 -6.90 -3.68 -2.58 -5.45 -4.67 -0.41 -7.56 -3.15 -8.55 -7.69 -7.52
None -0.08 0.44 -3.46 -3.15 -3.37 1.37 5.14 -1.89 -2.27 -3.06 0.38 1.35 -3.37 -3.41 -3.86
Nuclear Periphery -7.44 -14.69 -2.10 4.83 5.85 8.12 -7.05 3.86 -4.36 7.83 -1.44 -12.63 -0.57 0.40 9.29
Nuclear Periphery Foci -7.52 -2.68 7.83 11.59 11.57 7.84 -0.02 9.03 2.72 8.03 1.06 2.74 11.46 12.22 11.35
Nucleolus -0.44 4.31 -6.74 -5.32 -7.54 1.50 -0.50 -1.29 -7.13 -1.88 2.66 1.87 -6.56 -8.72 -8.39
Nucleus 1.77 -1.58 -19.64 -20.05 -19.46 2.31 -5.39 -11.47 -12.69 -3.45 3.57 -4.12 -22.71 -23.79 -21.46
Peroxisomes 4.99 -0.65 -0.83 -2.69 -0.45 -2.59 1.82 -2.97 -0.90 -5.19 3.40 -1.71 -1.21 -2.66 -0.01
Vacuole -8.38 -8.58 -9.57 1.16 -1.96 11.35 -19.09 -8.72 -20.54 13.40 7.14 -12.44 -13.06 -20.04 -0.49
Vacuole Periphery -5.24 11.23 26.06* 23.43* 22.51* 13.15 13.88 21.19 14.17 4.36 7.95 18.35 32.78 28.88 20.10*
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L6B; binds 5.8S rRNA; homologous to mammalian ribosomal protein L6, no bacterial homolog; RPL6B has a paralog, RPL6A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (86%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl6b

Rpl6b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl6b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available