Standard name
Human Ortholog
Description Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24,

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.11 0.12 0.07 0.09 0.14 0.13 0.14 0.18 0.15 0.17 0 0.06 0 0.06 0.11 0.1 0 0 0 0.06 0.08 0.05
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0.05 0.05 0 0.08 0.11 0.08 0.11 0.07 0.07 0.13 0.59 0.11 0.33 0 0 0 0 0 0
Cytoplasm 0.1 0.1 0.08 0.15 0.14 0.18 0.13 0.13 0.16 0.08 0.13 0.13 0.08 0.07 0.08 0.24 0.37 0.33 0 0 0 0 0 0
Endoplasmic Reticulum 0.89 0.91 0.88 0.79 0.84 0.79 0.77 0.72 0.59 0.58 0.6 0.54 0.91 0.88 0.85 0 0 0.05 0.89 0.95 0.91 0.81 0.78 0.79
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0.07 0 0 0.05 0.05 0.08 0.09 0.07 0.06 0.05 0.06 0 0.12 0.34 0.25 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.07 0.09 0.18 0.16 0.22 0.22 0 0 0 0.06 0.06 0.05 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0.05 0.11 0.05 0.06 0 0 0 0 0.11 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 13 18 16 17 26 49 41 38 64 48 68 8 19 7 1 4 4 3 1 3 14 22 18
Bud 2 0 1 1 2 2 3 10 6 10 15 11 0 1 0 0 0 0 3 1 0 0 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1
Bud Site 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0
Cell Periphery 3 9 3 6 10 15 17 9 21 38 25 42 24 21 41 10 4 13 0 0 1 6 11 11
Cytoplasm 25 28 13 21 33 52 45 43 43 28 41 52 26 21 25 4 13 13 7 6 3 5 7 8
Endoplasmic Reticulum 225 263 138 108 195 223 260 229 161 203 193 214 315 261 266 0 0 2 238 287 151 200 236 274
Endosome 0 0 0 0 1 1 1 2 1 7 0 0 0 1 1 0 0 0 0 0 0 1 1 0
Golgi 9 3 4 10 9 4 16 17 23 31 23 22 17 19 8 2 12 10 1 1 1 6 10 12
Mitochondria 0 1 3 5 4 13 24 29 49 57 71 88 0 0 0 1 2 2 1 0 0 2 2 6
Nucleus 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 2 0 0 1 3 3 6 1 6 10 2 5 0 0 0 0 0 0 2 1 0 0 0 0
Nucleolus 2 0 0 0 0 0 1 2 3 5 5 3 0 1 1 0 0 0 2 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0
Vac/Vac Membrane 6 2 2 3 4 2 12 17 15 37 15 25 5 5 3 0 4 0 1 1 1 4 2 3
Unique Cell Count 254 289 157 136 232 284 339 320 275 350 323 393 345 298 312 17 35 40 269 303 166 247 305 347
Labelled Cell Count 282 319 182 171 278 341 436 402 367 490 439 530 395 349 353 18 39 44 269 303 166 247 305 347


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 34.4 40.3 23.7 23.2 23.0 19.6 19.4 19.4 18.8 17.5 18.9 18.9 33.4 32.9 32.0 42.7 43.8 44.6 33.8 34.3 34.1
Std Deviation (1e-4) 8.8 6.6 5.3 5.7 4.8 4.2 4.1 4.6 4.7 3.7 4.7 4.6 7.5 7.3 6.3 10.3 13.0 13.5 7.5 7.6 8.7
Intensity Change (Log2) -0.03 -0.04 -0.28 -0.29 -0.29 -0.33 -0.44 -0.33 -0.33 0.49 0.47 0.43 0.85 0.88 0.91 0.51 0.53 0.52

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002040WT3HU80HU120HU16002040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302040WT1AF100AF140AF18002040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.1 -1.4 -0.8 0.9 0.4 0.7 1.9 1.0 1.7 -4.3 -1.9 -4.2 0 0 0
Bud 0 0 0 0 0 0 0 2.3 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 1.3 1.7 1.6 0 2.5 3.4 2.6 3.4 2.3 2.3 3.9 0 0 0
Cytoplasm 1.9 1.8 2.8 1.6 1.6 2.2 -0.1 1.4 1.6 -0.3 -0.5 -0.1 0 0 4.0
Endoplasmic Reticulum -2.0 -1.1 -2.4 -2.9 -4.0 -6.4 -6.6 -6.3 -7.4 1.2 -0.1 -0.8 -8.5 -10.5 -10.3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 1.9 0.7 0 1.1 1.4 2.4 2.6 2.0 1.5 1.2 1.8 0 0 0 0
Mitochondria 0 0 1.4 2.4 2.9 4.9 4.6 5.7 5.8 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.1 2.1 3.6 1.9 2.5 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 33.6626 40.8907 38.7823 37.4333 33.5462 38.7681 34.4127 40.8635 36.5257 33.0278 38.661 35.4292 41.1645 43.9843 45.2433 42.1051 42.39 41.6794
Actin 0.0191 0.0005 0.0145 0.0006 0.0023 0.0009 0.0184 0.0007 0.0255 0.0006 0 0.0108 0.003 0 0 0 0 0.0005
Bud 0.0002 0 0.0001 0 0.0001 0.0002 0.0002 0.0002 0.0001 0 0 0 0 0 0 0 0 0
Bud Neck 0.0023 0.0001 0.0003 0.0001 0.0035 0.0002 0.0011 0.0002 0.0003 0 0.0001 0.0009 0.0001 0.0001 0 0 0 0.0003
Bud Periphery 0.0004 0 0.0002 0.0001 0.0002 0.0004 0.0004 0.0004 0.0002 0.0001 0 0.0002 0.0001 0 0 0 0 0
Bud Site 0.002 0 0.0004 0.0001 0.0002 0 0.0088 0.0043 0.0016 0 0 0.0001 0.0005 0 0 0 0 0
Cell Periphery 0.0094 0.0065 0.0071 0.0033 0.0038 0.0016 0.0102 0.0131 0.0033 0.0029 0.0014 0.0018 0.0032 0.0047 0.004 0.0087 0.0023 0.0024
Cytoplasm 0.0073 0.0324 0.0105 0.0006 0.0271 0.0027 0.0086 0.0069 0.0031 0.0008 0.0008 0.0017 0.0057 0.007 0.001 0.0003 0.0005 0.0018
Cytoplasmic Foci 0.0126 0.0009 0.0025 0.0011 0.0217 0.0005 0.0146 0.0001 0.0138 0.0009 0.0003 0.0003 0.0006 0.0001 0 0 0.0001 0.0004
Eisosomes 0.0023 0.0001 0.0006 0.004 0.0001 0.0003 0.001 0.0001 0.0007 0.0003 0 0.0002 0.0002 0.0001 0.0001 0.0004 0.0001 0.0001
Endoplasmic Reticulum 0.8326 0.9133 0.8995 0.8954 0.8311 0.9543 0.8476 0.9452 0.8982 0.8567 0.9535 0.92 0.9392 0.9717 0.9832 0.9769 0.9513 0.9606
Endosome 0.0108 0.0012 0.0027 0.0088 0.0062 0.0049 0.0199 0.0007 0.0039 0.0201 0.0013 0.005 0.0021 0.0003 0.0004 0.0003 0.0006 0.0019
Golgi 0.0104 0.0078 0.0077 0.016 0.014 0.0135 0.0086 0.0182 0.0086 0.0438 0.0049 0.0152 0.0061 0.0005 0.0014 0.0007 0.0203 0.0128
Lipid Particles 0.0185 0.0262 0.0316 0.023 0.0119 0.0025 0.0135 0.0008 0.0097 0.0233 0.0277 0.0021 0.0069 0.0041 0.0006 0.0014 0.0184 0.0062
Mitochondria 0.0092 0 0.0062 0.0342 0.0014 0.0019 0.0015 0.0001 0.0019 0.0017 0 0.0013 0.0009 0 0 0 0 0
None 0.0046 0.0001 0.0008 0.0005 0.0007 0.0008 0.0017 0 0.0023 0.0007 0 0.0001 0.0002 0 0 0 0 0
Nuclear Periphery 0.0336 0.0088 0.0075 0.0045 0.0179 0.0127 0.0246 0.0071 0.0122 0.0327 0.0083 0.0338 0.0265 0.0096 0.0078 0.01 0.0056 0.0113
Nucleolus 0.0008 0 0.0002 0.0001 0.005 0 0.0004 0 0.0016 0 0 0 0.0001 0 0 0 0 0
Nucleus 0.002 0.0002 0.0032 0.0001 0.0058 0.0003 0.0015 0.0003 0.0013 0.0002 0.0001 0.0006 0.0003 0.0002 0.0001 0 0 0.0001
Peroxisomes 0.0067 0 0.0007 0.0033 0.0292 0 0.0011 0 0.0043 0 0 0.0001 0.0007 0 0 0 0 0
Punctate Nuclear 0.0055 0.0001 0.0006 0 0.0049 0.0001 0.0062 0 0.004 0.0001 0 0 0.0001 0 0 0 0 0
Vacuole 0.0065 0.0016 0.0022 0.0024 0.0091 0.0012 0.007 0.001 0.0025 0.0028 0.001 0.0025 0.002 0.0015 0.001 0.0009 0.0004 0.0008
Vacuole Periphery 0.0032 0.0002 0.0008 0.0019 0.0037 0.0009 0.0031 0.0003 0.001 0.0123 0.0005 0.0034 0.0014 0.0001 0.0003 0.0002 0.0002 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 310.5494 251.2468 171.475 200.8341 259.8046 251.4231 243.4505 216.4377 230.1009 257.0634
Translational Efficiency 1.0644 1.1535 1.1484 1.1383 1.0528 1.2587 1.1409 0.8705 0.9489 1.0067

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
186 1303 2380 127 1668 902 940 1508 1854 2205 3320 1635

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1665.50 2157.60 3283.91 3132.96 2172.81 2080.24 3017.60 2875.36 2121.91 2125.95 3208.51 2895.37
Standard Deviation 366.50 493.08 550.55 476.16 438.18 415.89 506.12 614.10 457.65 464.62 551.55 608.44
Intensity Change Log 2 0.373472 0.979459 0.911571 -0.062812 0.473840 0.404181 0.142858 0.715226 0.646490

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000318 0.001192 0.000536 0.000309 0.000511 0.002176 0.001001 0.000920 0.000492 0.001594 0.000667 0.000873
Bud Neck 0.000569 0.000489 0.001467 0.007311 0.000240 0.000607 0.002014 0.004197 0.000273 0.000537 0.001622 0.004439
Bud Site 0.000726 0.001601 0.001448 0.006757 0.000726 0.003420 0.004013 0.010463 0.000726 0.002345 0.002174 0.010175
Cell Periphery 0.002163 0.002813 0.004068 0.038837 0.001971 0.002557 0.006778 0.016303 0.001990 0.002708 0.004835 0.018054
Cytoplasm 0.000214 0.001818 0.002426 0.000412 0.000591 0.001503 0.004613 0.018039 0.000553 0.001689 0.003045 0.016670
Cytoplasmic Foci 0.001462 0.002281 0.000928 0.000563 0.001939 0.004086 0.001728 0.006256 0.001891 0.003019 0.001155 0.005813
Eisosomes 0.000088 0.000508 0.000079 0.000770 0.000053 0.000089 0.000103 0.000087 0.000057 0.000336 0.000086 0.000140
Endoplasmic Reticulum 0.936711 0.877591 0.890939 0.693378 0.938705 0.873360 0.823957 0.740305 0.938505 0.875860 0.871974 0.736660
Endosome 0.008316 0.021366 0.015399 0.016273 0.011849 0.029354 0.021686 0.027216 0.011494 0.024634 0.017179 0.026366
Golgi 0.020320 0.028563 0.009062 0.020629 0.015454 0.018830 0.013882 0.017527 0.015942 0.024582 0.010427 0.017768
Lipid Particles 0.008279 0.033072 0.033695 0.125858 0.012659 0.040414 0.055281 0.059685 0.012220 0.036075 0.039807 0.064825
Mitochondria 0.000229 0.000847 0.000235 0.000204 0.000397 0.001560 0.000757 0.001621 0.000380 0.001138 0.000382 0.001511
Mitotic Spindle 0.002614 0.000185 0.000200 0.001977 0.000064 0.000622 0.001906 0.004760 0.000320 0.000364 0.000683 0.004544
None 0.000110 0.002072 0.001031 0.000089 0.000591 0.000317 0.000758 0.001593 0.000543 0.001354 0.000954 0.001477
Nuclear Periphery 0.002195 0.001238 0.005269 0.008641 0.000867 0.001426 0.007285 0.003585 0.001000 0.001315 0.005840 0.003978
Nuclear Periphery Foci 0.007344 0.011496 0.017291 0.029869 0.005012 0.010927 0.030278 0.048347 0.005246 0.011263 0.020968 0.046912
Nucleolus 0.000128 0.000029 0.000005 0.000015 0.000012 0.000061 0.000008 0.000172 0.000024 0.000042 0.000006 0.000160
Nucleus 0.000600 0.000093 0.000110 0.000238 0.000084 0.000229 0.000272 0.001044 0.000136 0.000149 0.000156 0.000981
Peroxisomes 0.000037 0.000196 0.000034 0.000030 0.000019 0.000187 0.000027 0.000099 0.000021 0.000193 0.000032 0.000094
Vacuole 0.003234 0.008907 0.014244 0.040979 0.005265 0.006215 0.021032 0.032724 0.005061 0.007805 0.016166 0.033365
Vacuole Periphery 0.004343 0.003645 0.001534 0.006860 0.002989 0.002061 0.002621 0.005057 0.003125 0.002997 0.001842 0.005197

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.06 -1.00 -0.44 1.56 0.42 -2.28 -1.25 -1.94 1.34 -0.20 -2.59 -0.82 -2.00 1.06 -1.23
Bud Neck 0.30 -3.31 -4.32 -4.41 -3.53 -2.79 -6.49 -6.26 -5.77 -3.58 -3.01 -7.07 -6.90 -6.56 -4.48
Bud Site -2.66 -2.70 -1.62 -1.45 -1.42 -2.70 -3.17 -8.13 -5.20 -4.37 -3.50 -4.10 -8.24 -6.81 -6.72
Cell Periphery -1.47 -4.70 -4.53 -4.45 -4.28 -1.73 -7.46 -10.93 -10.30 -6.28 -3.01 -10.75 -11.73 -11.16 -9.42
Cytoplasm -4.78 -8.08 -1.24 3.27 5.79 -3.49 -5.12 -9.36 -8.86 -6.43 -4.96 -8.38 -9.35 -8.70 -7.73
Cytoplasmic Foci -1.39 0.90 1.17 3.10 0.38 -2.40 0.33 -5.35 -2.08 -5.01 -2.28 1.79 -5.29 -3.64 -6.30
Eisosomes -1.37 0.32 -2.11 -0.57 -2.14 -3.01 -4.14 -3.60 0.09 1.28 -1.55 -3.65 -3.13 1.08 -1.97
Endoplasmic Reticulum 4.77 4.54 7.66 6.06 6.32 7.64 12.53 22.43 12.83 7.25 10.45 13.59 23.68 15.83 15.19
Endosome -8.19 -5.88 -3.58 2.12 -0.27 -8.81 -7.69 -10.92 0.78 -3.19 -10.83 -7.05 -11.39 -1.34 -6.89
Golgi -1.68 2.52 -0.03 1.85 -2.98 -1.46 0.78 -0.95 0.67 -1.80 -4.17 3.76 -0.87 3.48 -5.12
Lipid Particles -5.45 -6.32 -5.67 -4.52 -4.45 -6.39 -8.73 -13.33 -3.97 -0.75 -8.90 -11.80 -14.42 -7.13 -6.15
Mitochondria -1.27 -0.65 0.01 1.25 0.41 -1.44 -0.71 -2.61 -0.16 -1.35 -1.64 -0.19 -2.62 -0.74 -2.56
Mitotic Spindle 1.18 1.16 0.24 -1.57 -1.52 -2.55 -2.40 -5.11 -4.54 -2.80 -0.19 -1.34 -4.90 -4.93 -4.49
None -2.95 -3.48 0.42 2.98 3.57 1.89 -0.82 -2.24 -2.89 -1.73 -1.98 -1.85 -2.26 -0.29 -1.22
Nuclear Periphery 0.95 -3.04 -3.83 -5.37 -2.13 -2.14 -7.16 -10.91 -6.71 4.01 -1.73 -10.97 -10.96 -9.93 4.01
Nuclear Periphery Foci -1.18 -3.20 -2.65 -2.29 -1.44 -3.13 -9.08 -13.35 -10.54 -4.26 -4.45 -11.54 -13.57 -11.24 -7.81
Nucleolus 0.77 0.97 0.90 0.63 -1.76 -1.44 0.54 -1.28 -0.89 -1.31 -0.83 1.18 -1.19 -1.03 -1.32
Nucleus 0.93 0.70 0.59 -1.97 -0.50 -1.48 -2.74 -5.16 -4.54 -3.88 -0.22 -1.61 -4.95 -4.97 -4.50
Peroxisomes -1.94 0.18 -0.26 1.71 -0.39 -1.71 -1.10 -4.35 0.87 -3.71 -2.77 -1.44 -4.29 1.49 -3.49
Vacuole -4.95 -9.76 -5.79 -4.87 -3.76 -0.79 -7.70 -12.27 -11.65 -4.23 -3.04 -10.86 -13.27 -12.04 -7.40
Vacuole Periphery 0.52 2.45 -0.96 -1.29 -2.18 1.57 0.38 -2.67 -4.36 -3.11 0.19 2.42 -2.80 -3.12 -5.32
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24,
Localization
Cell Percentages ER (98%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Erv25

Erv25


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erv25-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available