Standard name
Human Ortholog
Description Uracil-DNA glycosylase; required for repair of uracil in DNA formed by spontaneous cytosine deamination; efficiently excises uracil from single-stranded DNA in vivo; not required for strand-specific mismatch repair; cell-cycle regulated, expressed in late G1; localizes to mitochondria and nucleus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.08 0.06 0.06 0 0 0 0 0.05 0 0.05 0.12 0.16 0.18 0.05 0 0.07 0 0 0 0.05 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.18 0 0 0.06 0.06 0.2 0.32 0.2 0.42 0.29 0.56 0.34 0 0 0 0 0 0 0 0 0 0.08 0.07 0.07
Nucleus 0.91 0.91 0.89 0.91 0.88 0.88 0.81 0.82 0.75 0.77 0.71 0.77 0.87 0.83 0.79 0.88 0.86 0.9 0.85 0.82 0.75 0.5 0.44 0.42
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0 0.08 0.09 0.14 0.26 0.3 0.29
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 1 2
Bud 0 0 0 1 2 3 9 8 7 10 7 8 0 0 0 0 0 1 6 11 8 2 10 13
Bud Neck 0 0 0 0 0 0 0 0 0 1 1 2 0 1 1 0 1 0 0 0 0 1 4 5
Bud Site 0 0 1 0 3 9 7 2 14 14 18 13 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0
Cytoplasm 11 30 30 20 35 13 26 28 29 29 18 27 24 42 64 15 12 20 3 6 6 15 17 14
Endoplasmic Reticulum 0 2 2 0 1 0 0 1 0 0 0 0 0 0 0 10 4 3 1 1 1 0 2 4
Endosome 0 6 0 1 5 0 0 2 2 0 0 0 0 2 2 2 5 0 2 5 2 3 8 12
Golgi 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 1 6 1 0 1 1
Mitochondria 92 6 11 19 33 86 226 134 296 186 252 170 1 1 0 13 13 12 7 3 13 27 33 34
Nucleus 469 578 332 302 497 384 561 555 524 486 322 391 175 222 278 260 304 257 454 545 310 167 223 210
Nuclear Periphery 1 1 0 2 3 1 3 0 15 1 4 3 0 0 0 7 1 1 0 2 1 1 3 3
Nucleolus 1 0 0 0 5 1 30 15 18 25 10 3 0 0 0 2 4 0 1 3 1 8 14 16
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0
SpindlePole 0 0 3 3 3 4 3 9 3 10 3 3 3 2 7 0 4 1 8 11 5 8 16 18
Vac/Vac Membrane 21 35 4 6 24 6 9 18 13 27 14 18 4 8 11 14 27 5 44 56 57 85 152 146
Unique Cell Count 518 636 374 333 567 436 696 673 698 634 451 506 202 269 352 294 353 285 534 663 416 335 502 500
Labelled Cell Count 595 660 383 354 611 507 874 772 921 789 649 638 209 278 364 326 376 301 534 663 416 335 502 500


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 6.9 5.8 5.6 6.0 5.2 4.9 5.6 4.5 5.0 4.5 4.9 6.0 6.2 6.1 7.9 8.5 8.3 5.8 6.0 6.3
Std Deviation (1e-4) 0.7 1.4 1.2 1.5 1.6 1.4 1.2 1.3 1.1 1.3 1.3 1.3 1.1 1.3 1.2 1.7 1.9 1.9 1.6 1.5 1.7
Intensity Change (Log2) – – – -0.06 0.05 -0.17 -0.25 -0.05 -0.38 -0.23 -0.38 -0.24 0.05 0.1 0.07 0.44 0.55 0.52 -0.01 0.04 0.11


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2.5 0 2.7 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.0 -1.1 -3.2 -3.0 -2.6 -2.6 -2.3 -2.5 -1.6 1.5 3.0 4.1 -1.5 -2.7 -0.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.8 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.8 2.0 7.3 0 7.6 0 10.2 0 11.1 0 -2.4 -3.2 1.0 0.6 0.9
Nucleus 0.8 -0.5 -0.3 -3.4 -2.7 -5.3 -4.8 -6.1 -4.4 -0.8 -2.3 -3.6 -0.1 -1.1 0.6
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 2.9 0 3.9 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 2.8 0 0 1.7 1.0 2.8 2.0 2.3 0 1.8 1.9 2.9 4.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.8157 2.6661 2.7495 2.5638 1.6364 2.5605 1.5343 2.2582 2.4298 1.6963 1.267 1.8419 2.3618 2.1179 1.9282 2.1485 3.284 1.8049
Actin 0.0365 0.0001 0.0324 0.0214 0.0002 0.0057 0.0082 0 0.0034 0 0.0005 0.0006 0.0127 0.0008 0.0001 0.033 0.0129 0.0025
Bud 0.0006 0.0001 0.0014 0.0032 0 0.0002 0.0001 0 0.0004 0 0.0001 0 0.0009 0 0 0.0004 0.0034 0.0001
Bud Neck 0.0026 0.0004 0.0023 0.0005 0.0004 0.0016 0.0008 0.0002 0.0009 0.0001 0.0018 0.0016 0.007 0.0003 0.0001 0.0017 0.0018 0.0013
Bud Periphery 0.0012 0.0002 0.0028 0.0058 0 0.0007 0.0001 0 0.0006 0 0.0001 0.0001 0.0021 0.0001 0.0001 0.0004 0.0057 0.0001
Bud Site 0.003 0.0018 0.0026 0.002 0 0.0003 0.0003 0.0003 0.0012 0 0.0004 0.0002 0.0114 0.0004 0.0002 0.0018 0.0345 0.0002
Cell Periphery 0.0005 0.0001 0.0004 0.0004 0 0.0002 0 0 0.0001 0 0 0 0.0012 0 0.0001 0.0002 0.0004 0
Cytoplasm 0.0227 0.0122 0.0027 0.0191 0.0068 0.0061 0.004 0.0036 0.0017 0.0003 0.0028 0.0013 0.0162 0.0075 0.0036 0.0047 0.0452 0.0022
Cytoplasmic Foci 0.0129 0.0007 0.0064 0.0034 0.0001 0.0025 0.0007 0.0001 0.002 0 0.0002 0.0003 0.0138 0.0012 0.0059 0.0163 0.0242 0.004
Eisosomes 0.0003 0 0 0.0002 0 0 0.0001 0 0 0 0 0 0.0003 0 0 0.0001 0.0002 0
Endoplasmic Reticulum 0.0034 0.0004 0.0006 0.0048 0.0002 0.0006 0.0006 0.0002 0.0003 0 0.0003 0.0001 0.0103 0.0009 0.0002 0.0004 0.0016 0.0001
Endosome 0.03 0.0008 0.0118 0.023 0.0004 0.0051 0.0036 0.0009 0.0011 0 0.0006 0.0005 0.0306 0.0007 0.0014 0.0136 0.0377 0.0029
Golgi 0.0101 0.0002 0.0045 0.0132 0 0.0055 0.0009 0 0.0005 0 0.0001 0.0003 0.007 0.0002 0.0005 0.007 0.0141 0.003
Lipid Particles 0.0134 0.0009 0.0032 0.018 0 0.0089 0.0034 0 0.0005 0 0.0001 0.0013 0.0225 0.0004 0.0013 0.0026 0.031 0.0114
Mitochondria 0.0111 0.0016 0.0117 0.0393 0.0003 0.0035 0.0016 0.0001 0.0012 0.0001 0.0003 0.0022 0.022 0.0002 0.0055 0.0014 0.0175 0.0038
None 0.0083 0.0197 0.0003 0.0033 0.0022 0.0066 0.0107 0.0031 0.0005 0.0001 0.0669 0.0002 0.0185 0.0064 0.0084 0.0005 0.0027 0.0045
Nuclear Periphery 0.0255 0.0061 0.0078 0.0228 0.0109 0.0045 0.0145 0.0067 0.0041 0.0013 0.0051 0.0034 0.0207 0.0069 0.0033 0.001 0.0194 0.0031
Nucleolus 0.0118 0.0102 0.0044 0.0046 0.0105 0.0119 0.0129 0.0066 0.0053 0.0031 0.0206 0.0139 0.014 0.007 0.0039 0.0039 0.0206 0.0126
Nucleus 0.7798 0.932 0.891 0.801 0.9469 0.93 0.8967 0.9551 0.9655 0.9942 0.8834 0.9662 0.753 0.9581 0.9581 0.9012 0.6879 0.9297
Peroxisomes 0.0034 0.0003 0.0035 0.0024 0 0.0037 0.0009 0 0.001 0 0 0.0031 0.0114 0.0018 0.0018 0.0058 0.0104 0.0051
Punctate Nuclear 0.0089 0.0111 0.0007 0.0055 0.0208 0.001 0.0389 0.0219 0.0092 0.0008 0.0163 0.0043 0.008 0.006 0.0043 0.0027 0.0179 0.0131
Vacuole 0.0102 0.0008 0.0071 0.003 0.0001 0.0008 0.0005 0.0009 0.0005 0 0.0003 0.0003 0.0116 0.0009 0.0007 0.0013 0.0075 0.0003
Vacuole Periphery 0.004 0.0002 0.0022 0.0033 0.0001 0.0006 0.0004 0.0003 0.0002 0 0.0001 0.0002 0.0049 0.0002 0.0002 0.0002 0.0032 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 40.356 21.9195 15.5875 18.1282 27.1551 25.5276 15.9295 13.7118 19.683 31.0694
Translational Efficiency 1.1162 0.8758 0.7812 0.8216 1.2499 2.0212 1.5095 1.1263 0.9861 1.3543

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1897 1354 2645 921 1467 1952 209 1496 3364 3306 2854 2417

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 724.93 812.08 895.60 943.66 691.07 764.42 967.39 950.92 710.16 783.94 900.86 948.15
Standard Deviation 101.35 121.46 143.01 146.72 93.34 103.56 132.91 147.47 99.37 113.68 143.51 147.23
Intensity Change Log 2 — 0.163780 0.305013 0.380425 — 0.145534 0.485266 0.460492 — 0.154904 0.395799 0.420057

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000105 0.000469 0.000479 0.000872 0.000195 0.000154 0.000585 0.004295 0.000144 0.000283 0.000487 0.002991
Bud Neck 0.003904 0.011769 0.019434 0.015768 0.003598 0.004267 0.003615 0.030796 0.003771 0.007339 0.018275 0.025070
Bud Site 0.000958 0.002974 0.002593 0.004360 0.001184 0.000674 0.000601 0.021878 0.001056 0.001616 0.002447 0.015202
Cell Periphery 0.000183 0.000219 0.000184 0.000181 0.000235 0.000131 0.000065 0.000236 0.000205 0.000167 0.000175 0.000215
Cytoplasm 0.028695 0.026641 0.009763 0.025121 0.038495 0.008231 0.004770 0.063071 0.032969 0.015771 0.009397 0.048610
Cytoplasmic Foci 0.002582 0.002512 0.000266 0.000318 0.004014 0.000344 0.001117 0.002112 0.003207 0.001232 0.000329 0.001428
Eisosomes 0.000014 0.000021 0.000022 0.000029 0.000020 0.000013 0.000041 0.000031 0.000017 0.000016 0.000023 0.000030
Endoplasmic Reticulum 0.003108 0.007944 0.004896 0.009114 0.002410 0.004017 0.005985 0.008274 0.002804 0.005625 0.004976 0.008594
Endosome 0.000463 0.001437 0.000611 0.000695 0.000780 0.000825 0.000269 0.004964 0.000602 0.001076 0.000586 0.003337
Golgi 0.000056 0.000436 0.000117 0.000124 0.000146 0.000036 0.000044 0.001940 0.000095 0.000200 0.000112 0.001248
Lipid Particles 0.000653 0.001165 0.000079 0.000250 0.001026 0.000276 0.000595 0.000461 0.000815 0.000640 0.000117 0.000381
Mitochondria 0.001126 0.001834 0.001920 0.002033 0.001142 0.000925 0.000644 0.008658 0.001133 0.001297 0.001827 0.006133
Mitotic Spindle 0.001026 0.004294 0.003467 0.009268 0.002035 0.000614 0.000239 0.039775 0.001466 0.002121 0.003231 0.028150
None 0.008831 0.007540 0.003090 0.006089 0.013489 0.004699 0.003631 0.007387 0.010862 0.005863 0.003129 0.006892
Nuclear Periphery 0.001570 0.001547 0.001518 0.001546 0.000731 0.001025 0.000556 0.004402 0.001204 0.001239 0.001448 0.003314
Nuclear Periphery Foci 0.000187 0.000677 0.000131 0.000249 0.000378 0.000231 0.000083 0.000812 0.000270 0.000414 0.000127 0.000597
Nucleolus 0.003670 0.006810 0.001358 0.001358 0.007244 0.004606 0.003490 0.001557 0.005228 0.005509 0.001514 0.001481
Nucleus 0.940617* 0.915421* 0.947260* 0.913649* 0.920097* 0.966496* 0.970330* 0.768837* 0.931669* 0.945578* 0.948949* 0.824017*
Peroxisomes 0.000472 0.000656 0.000148 0.000168 0.000760 0.000146 0.000205 0.000769 0.000598 0.000355 0.000152 0.000540
Vacuole 0.001491 0.004862 0.002444 0.008653 0.001742 0.001897 0.003061 0.025636 0.001601 0.003112 0.002489 0.019164
Vacuole Periphery 0.000289 0.000770 0.000221 0.000158 0.000280 0.000392 0.000074 0.004112 0.000285 0.000547 0.000211 0.002605

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.01 -13.28 -14.72 -8.28 -8.80 1.16 -6.78 -2.89 -2.96 -1.87 -4.94 -12.13 -3.85 -3.55 -2.98
Bud Neck -7.25 -16.60 -12.38 -5.07 0.71 -1.04 -2.59 -15.65 -15.67 -13.98 -6.15 -17.42 -19.40 -15.76 -4.79
Bud Site -4.53 -3.83 -6.01 -2.91 -3.51 1.50 0.11 -7.60 -8.09 -7.76 -2.07 -3.58 -8.95 -8.48 -7.45
Cell Periphery -1.43 0.77 0.50 2.01 -0.34 1.99 3.01 1.05 -2.82 -6.61 1.49 1.66 1.11 -0.76 -1.06
Cytoplasm 0.33 8.61 1.67 1.23 -5.09 10.06 10.83 -3.74 -14.95 -15.52 8.24 12.60 -3.49 -11.08 -14.88
Cytoplasmic Foci 0.09 4.54 4.39 4.10 -0.88 6.03 4.11 4.54 -3.42 -0.41 4.29 7.31 5.81 1.65 -3.46
Eisosomes -4.30 -7.55 -14.11 -9.34 -10.15 5.22 -6.92 -8.94 -14.36 2.72 0.66 -7.54 -16.19 -16.74 -10.49
Endoplasmic Reticulum -11.41 -8.93 -15.60 -5.53 -11.45 -5.37 -8.29 -17.17 -11.94 -1.43 -11.17 -13.27 -22.55 -12.37 -13.45
Endosome -3.44 -0.32 -2.80 2.34 -1.39 -0.12 3.11 -3.59 -3.31 -4.40 -2.54 0.43 -4.13 -2.39 -3.96
Golgi -1.47 -0.90 -3.19 1.16 -0.55 2.84 2.05 -2.56 -3.03 -2.91 -0.94 -0.07 -2.85 -1.89 -2.74
Lipid Particles -1.23 6.33 2.54 1.84 -8.79 4.52 2.39 2.73 -4.68 -0.03 1.06 7.89 3.30 0.60 -12.79
Mitochondria -2.21 -3.13 -4.23 -2.32 -1.52 0.74 1.12 -4.67 -4.89 -5.03 -0.71 -3.82 -5.35 -5.13 -4.03
Mitotic Spindle -2.74 -3.17 -4.38 -2.70 -3.21 1.72 1.15 -8.26 -8.95 -8.71 -1.04 -2.45 -9.50 -9.09 -8.38
None 0.93 5.80 3.39 2.35 -2.52 6.45 7.11 5.39 -1.77 -3.14 5.33 9.82 5.86 0.32 -5.34
Nuclear Periphery -0.06 -0.81 -4.94 -5.40 -4.03 -1.98 -1.56 -6.97 -6.23 -6.56 -0.46 -2.88 -7.33 -7.08 -5.81
Nuclear Periphery Foci -3.49 0.80 -4.03 1.69 -4.58 1.15 1.60 -2.04 -4.73 -5.79 -1.50 1.79 -3.99 -2.19 -7.14
Nucleolus -3.63 5.74 3.51 5.68 -1.29 3.40 4.78 9.64 6.52 2.63 -0.74 10.37 9.78 8.55 -0.38
Nucleus 4.82 -0.89 8.04 3.37 9.22 -9.31 -7.26 16.48 25.13 22.86 -3.67 -4.10 19.31 22.23 22.93
Peroxisomes -0.90 1.64 1.48 3.33 -0.62 2.51 2.17 1.34 -2.22 -1.48 1.38 2.78 1.67 0.56 -1.88
Vacuole -4.92 -3.55 -9.66 -7.82 -8.95 -0.47 -3.99 -14.67 -14.42 -12.42 -3.48 -4.40 -17.30 -16.24 -16.40
Vacuole Periphery -2.45 0.69 1.10 3.67 0.58 -0.83 4.24 -3.06 -2.77 -3.45 -2.19 1.05 -2.86 -1.97 -3.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Uracil-DNA glycosylase; required for repair of uracil in DNA formed by spontaneous cytosine deamination; efficiently excises uracil from single-stranded DNA in vivo; not required for strand-specific mismatch repair; cell-cycle regulated, expressed in late G1; localizes to mitochondria and nucleus
Localization
Cell Percentages nucleus (87%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Ung1

Ung1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ung1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available