Standard name
Human Ortholog
Description Protein that stimulates strand exchange; stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0.06 0 0 0.06 0.07 0.05 0.07 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 0 0 0 0 0 0 0.08 0.1 0.13 0.1 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.14 0 0.09 0.06 0 0.15 0.17 0.13 0.21 0.24 0.24 0.2 0 0 0 0.09 0.05 0.05 0 0 0 0 0 0
Nucleus 0.92 0.92 0.91 0.89 0.87 0.83 0.79 0.73 0.74 0.71 0.77 0.76 0.84 0.83 0.81 0.76 0.81 0.79 0.87 0.88 0.85 0.86 0.74 0.66
Nuclear Periphery 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.11 0.09 0.1 0.1 0.12 0.16 0.21 0.29 0.28 0.33 0.31 0.33 0.05 0.11 0.06 0.07 0.06 0.06 0.06 0 0.05 0.05 0.08 0.08
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.09 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 2 0 2 0 4 1 2 0 0 0 0 0 0 1 4 0 0 1 4
Bud Neck 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 2 23 16 9 22 25 22 38 3 1 0 1 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 4 4 2 3 15 5 11 12 9 3 6 3 17 43 49 23 11 6 0 0 0 0 1 1
Endoplasmic Reticulum 0 0 1 1 0 0 1 0 1 0 0 0 1 0 0 8 5 2 0 0 0 0 0 1
Endosome 1 2 1 2 3 0 1 3 0 0 0 1 1 2 1 10 5 5 0 3 2 0 5 3
Golgi 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 2
Mitochondria 26 9 23 14 11 55 72 74 80 93 96 108 2 0 2 22 6 4 0 2 1 0 3 7
Nucleus 171 313 235 210 257 311 337 414 275 272 313 411 185 347 301 176 97 67 163 310 231 100 211 164
Nuclear Periphery 2 12 3 5 5 8 21 11 14 8 9 10 5 7 7 4 3 0 0 0 2 0 0 3
Nucleolus 20 30 27 24 36 61 89 166 105 127 126 178 12 45 22 17 7 5 11 7 13 5 23 19
Peroxisomes 0 0 0 0 1 2 0 0 0 0 1 1 3 7 8 5 1 0 0 0 0 0 0 0
SpindlePole 1 4 0 3 1 4 2 7 1 1 0 2 4 7 5 8 3 1 1 11 4 1 3 2
Vac/Vac Membrane 0 5 0 0 0 3 4 8 0 0 1 3 3 4 4 5 1 2 6 10 14 4 25 34
Unique Cell Count 185 339 259 235 297 376 426 566 374 382 405 544 219 419 372 232 120 85 188 353 272 117 285 248
Labelled Cell Count 225 379 292 264 331 474 554 706 507 534 576 759 236 463 399 279 140 92 188 353 272 117 285 248


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 6.8 6.2 6.5 7.0 6.4 5.9 6.1 5.9 5.5 5.6 5.5 8.1 7.9 7.6 7.2 8.2 8.8 6.4 6.6 7.2
Std Deviation (1e-4) 1.6 1.3 1.2 1.9 1.9 1.7 1.8 1.7 1.6 1.4 1.6 1.5 2.3 2.4 2.5 1.9 2.1 1.9 2.0 1.7 1.5
Intensity Change (Log2) – – – 0.07 0.17 0.05 -0.08 -0.03 -0.06 -0.18 -0.15 -0.17 0.39 0.35 0.3 0.22 0.42 0.52 0.05 0.09 0.22

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 4.1 3.2 0 4.0 4.2 3.8 4.4 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 2.9 0 0 0 0 0 0 0 3.9 4.8 5.6 4.6 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 2.9 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.2 -2.5 2.2 2.9 1.7 4.2 5.0 4.9 3.9 -3.9 -6.2 -5.3 0.2 -1.3 -1.2
Nucleus -0.5 -1.5 -2.9 -4.0 -5.7 -5.4 -6.0 -4.5 -5.1 -2.1 -2.9 -3.4 -4.5 -2.7 -2.9
Nuclear Periphery 0 0 0 2.6 0 2.0 0 0 0 0 0 0 0 0 0
Nucleolus -0.1 0.6 2.1 3.5 6.0 5.4 6.6 6.2 6.8 -2.0 0.1 -2.1 -1.2 -1.5 -1.3
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.1764 3.2001 2.6329 2.5027 1.7277 2.4237 2.9295 3.8184 3.3282 2.9112 3.0077 3.2679 4.3392 3.4925 3.4171 2.9801 3.5259 3.4884
Actin 0.0018 0.0001 0 0.0001 0 0 0.0148 0.0061 0.005 0.012 0 0.0026 0.1561 0 0.0081 0 0.0001 0.0019
Bud 0.0003 0.0001 0.0001 0.0004 0.0001 0 0.0002 0 0.0001 0.0001 0 0 0.0047 0 0.0008 0 0.0002 0.0001
Bud Neck 0.0014 0.0002 0.0001 0.0007 0.0009 0.0024 0.0011 0.0002 0.0004 0.0008 0.0002 0.0015 0.0017 0.0001 0.0006 0.0001 0.0011 0.0021
Bud Periphery 0.0005 0.0001 0.0001 0.0002 0.0002 0.0002 0.0004 0 0.0005 0.0002 0 0.0002 0.0073 0 0.0006 0 0.0005 0.0003
Bud Site 0.0023 0.0005 0.0002 0.0003 0.0002 0.0001 0.0017 0.0001 0.0002 0.0014 0 0.0001 0.0064 0.0001 0.0049 0 0.0013 0.0002
Cell Periphery 0.0003 0 0 0.0001 0.0001 0.0001 0.0002 0 0.0001 0.0001 0 0 0.0013 0 0.0002 0 0.0003 0.0001
Cytoplasm 0.0085 0.0211 0.0002 0.0066 0.0001 0.0001 0.003 0.0002 0.0003 0.0012 0 0.0001 0.042 0.0001 0.0236 0.0002 0.0002 0.0002
Cytoplasmic Foci 0.0098 0.009 0 0.0127 0 0 0.0085 0.0006 0.0018 0.0188 0.0001 0.0004 0.0097 0 0.0065 0.0001 0.0001 0.0009
Eisosomes 0.0001 0 0 0 0 0 0.0002 0 0.0004 0.0001 0 0 0.001 0 0.0001 0 0 0
Endoplasmic Reticulum 0.005 0.0001 0.0001 0.0001 0 0 0.0017 0 0.0003 0.0009 0 0.0001 0.0269 0 0.0029 0 0.0001 0.0003
Endosome 0.043 0.0009 0.0003 0.0002 0 0.0001 0.0116 0.0003 0.0015 0.0142 0 0.0009 0.0743 0 0.0145 0 0.0003 0.0035
Golgi 0.0035 0.0004 0 0 0 0 0.0038 0.0021 0.0006 0.0047 0 0.0017 0.0266 0 0.0155 0 0 0.0098
Lipid Particles 0.028 0.0078 0 0.0003 0 0 0.0215 0.0001 0.0027 0.023 0 0.0045 0.0146 0 0.0021 0 0.0001 0.0002
Mitochondria 0.0058 0.0003 0.0003 0.0005 0.0005 0.0001 0.0041 0.0006 0.0044 0.0013 0.0002 0.0035 0.0797 0.0001 0.004 0 0.0008 0.0137
None 0.0038 0.0001 0 0.001 0.0001 0 0.0015 0 0.0002 0.0012 0 0.0001 0.0404 0 0.0056 0 0.0002 0.0001
Nuclear Periphery 0.0075 0.0018 0.0027 0.005 0.001 0.0006 0.005 0.0026 0.0065 0.0136 0.0071 0.0052 0.1074 0.0006 0.024 0.0022 0.0015 0.0044
Nucleolus 0.039 0.0487 0.0354 0.07 0.11 0.0861 0.0353 0.0264 0.0343 0.0226 0.0784 0.0776 0.0467 0.014 0.0221 0.0174 0.2012 0.1061
Nucleus 0.8228 0.8822 0.8857 0.8759 0.8855 0.9081 0.8605 0.9166 0.8856 0.7321 0.8414 0.897 0.2891 0.933 0.8106 0.6952 0.6206 0.8366
Peroxisomes 0.0049 0.0004 0 0 0 0 0.0095 0.0001 0.0005 0.0096 0 0.0009 0.012 0 0.0012 0 0.0001 0.0002
Punctate Nuclear 0.0039 0.0261 0.0696 0.0246 0.001 0.0015 0.0133 0.0437 0.0522 0.14 0.0722 0.0031 0.0121 0.0518 0.0498 0.2845 0.1699 0.0186
Vacuole 0.0064 0.0002 0.0037 0.0007 0.0002 0.0004 0.0014 0 0.0012 0.0013 0 0.0002 0.0272 0.0001 0.0012 0 0.0012 0.0004
Vacuole Periphery 0.0015 0.0001 0.0014 0.0003 0.0001 0.0001 0.0007 0 0.001 0.0009 0.0002 0.0002 0.0129 0 0.0009 0 0.0003 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.5592 27.8637 27.3958 30.1384 18.1857 31.9312 30.6381 33.0383 35.2359 29.5384
Translational Efficiency 0.6832 0.8096 0.6963 0.6633 0.911 0.7183 0.768 0.5515 0.6091 0.607

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1458 939 177 1236 953 215 1896 128 2411 1154 2073 1364

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 719.15 833.63 1148.83 1218.31 803.69 932.24 1110.07 1158.97 752.57 852.00 1113.38 1212.74
Standard Deviation 102.64 145.99 139.80 226.97 111.49 129.48 158.15 209.77 113.98 148.12 157.04 226.07
Intensity Change Log 2 — 0.213114 0.675801 0.760517 — 0.214062 0.465940 0.528132 — 0.213615 0.568856 0.642547

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000217 0.000891 0.002295 0.002082 0.000430 0.000842 0.000774 0.001221 0.000301 0.000882 0.000904 0.002001
Bud Neck 0.005531 0.007385 0.012919 0.027277 0.004472 0.007323 0.018904 0.014800 0.005113 0.007373 0.018393 0.026106
Bud Site 0.002518 0.001011 0.001800 0.005463 0.000726 0.002348 0.000977 0.004783 0.001810 0.001260 0.001047 0.005399
Cell Periphery 0.000161 0.000140 0.000069 0.000122 0.000089 0.000056 0.000050 0.000132 0.000132 0.000124 0.000052 0.000123
Cytoplasm 0.014078 0.001630 0.000428 0.001879 0.001638 0.000509 0.000422 0.001909 0.009161 0.001421 0.000422 0.001882
Cytoplasmic Foci 0.007112 0.000965 0.000213 0.007898 0.000531 0.000857 0.000771 0.005864 0.004511 0.000945 0.000723 0.007708
Eisosomes 0.000024 0.000033 0.000065 0.000040 0.000025 0.000032 0.000033 0.000042 0.000025 0.000033 0.000036 0.000040
Endoplasmic Reticulum 0.001951 0.005694 0.008194 0.002329 0.003852 0.004840 0.002249 0.003142 0.002702 0.005535 0.002757 0.002405
Endosome 0.001592 0.000886 0.000288 0.002762 0.000349 0.001571 0.000180 0.016418 0.001101 0.001013 0.000190 0.004043
Golgi 0.000795 0.000327 0.000209 0.002550 0.000188 0.000612 0.000142 0.003807 0.000555 0.000380 0.000147 0.002668
Lipid Particles 0.000652 0.000385 0.000310 0.000547 0.000439 0.000263 0.000033 0.000653 0.000568 0.000362 0.000056 0.000557
Mitochondria 0.001126 0.003977 0.002130 0.007604 0.001186 0.005607 0.001585 0.002404 0.001150 0.004280 0.001631 0.007116
Mitotic Spindle 0.019773 0.005911 0.007197 0.112891 0.005142 0.007522 0.008968 0.080028 0.013990 0.006211 0.008817 0.109807
None 0.021415 0.005955 0.001157 0.002048 0.004894 0.001254 0.001318 0.007565 0.014885 0.005079 0.001305 0.002566
Nuclear Periphery 0.001246 0.000690 0.000702 0.002866 0.000609 0.000398 0.000445 0.001400 0.000994 0.000636 0.000467 0.002729
Nuclear Periphery Foci 0.003522 0.002030 0.000516 0.004515 0.003035 0.000488 0.000564 0.001955 0.003330 0.001743 0.000560 0.004274
Nucleolus 0.056906 0.070416 0.041917 0.096792 0.043603 0.052148 0.048454 0.057836 0.051648 0.067013 0.047896 0.093136
Nucleus 0.857346 0.889001 0.914310 0.705747 0.926770 0.908459 0.912533 0.758684 0.884788 0.892626 0.912685 0.710715
Peroxisomes 0.001489 0.001259 0.002059 0.005926 0.000720 0.001025 0.000780 0.006000 0.001185 0.001216 0.000889 0.005933
Vacuole 0.002124 0.000761 0.002959 0.005256 0.000420 0.001940 0.000564 0.023312 0.001450 0.000981 0.000768 0.006951
Vacuole Periphery 0.000419 0.000653 0.000266 0.003405 0.000884 0.001907 0.000255 0.008044 0.000603 0.000887 0.000255 0.003840

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -11.22 -10.52 -6.83 -4.00 2.06 -3.67 -8.92 -6.46 -4.06 -4.25 -10.82 -16.64 -7.08 -4.40 -3.80
Bud Neck -0.05 -3.71 -12.54 -12.43 -4.45 -1.65 -16.02 -4.72 -3.25 2.29 -1.44 -16.39 -13.83 -12.80 -3.82
Bud Site 4.97 2.57 -1.17 -6.56 -4.03 -1.45 -3.21 -2.69 -1.46 -2.27 3.69 3.52 -3.34 -6.38 -6.31
Cell Periphery 0.85 5.09 2.82 0.67 -2.64 1.95 2.84 -0.85 -1.95 -2.16 0.53 7.44 1.48 0.24 -5.67
Cytoplasm 8.43 9.45 8.60 0.48 -2.59 2.77 2.87 -0.25 -2.60 -2.66 8.32 9.81 8.18 -0.12 -3.31
Cytoplasmic Foci 5.50 6.48 1.27 -4.37 -5.44 -0.53 -1.08 -2.25 -2.04 -1.85 4.91 5.70 -0.66 -4.69 -5.24
Eisosomes -0.40 -7.11 -4.35 -4.80 4.76 -1.62 -3.94 -3.87 -2.52 -2.60 -1.51 -3.67 -6.77 -5.45 -4.72
Endoplasmic Reticulum -10.54 -8.53 -0.60 9.03 8.10 -1.64 5.86 0.48 1.78 -3.21 -9.03 0.04 1.72 9.31 1.82
Endosome 1.84 4.11 0.13 -1.42 -2.78 -1.31 1.86 -2.17 -1.87 -2.22 0.52 5.24 -2.09 -2.19 -3.94
Golgi 2.82 3.16 -1.22 -2.51 -2.60 -1.25 0.67 -1.56 -1.22 -1.59 1.77 3.80 -2.08 -2.68 -3.16
Lipid Particles 1.52 2.27 1.38 -0.01 -0.21 1.60 3.35 -0.18 -1.13 -1.98 1.62 6.38 1.07 -0.28 -2.75
Mitochondria -1.96 -3.83 -4.77 -1.26 -3.63 -1.14 -2.36 -3.52 0.74 -2.53 -2.26 -4.38 -4.89 -0.99 -4.24
Mitotic Spindle 6.11 1.65 -10.67 -14.69 -9.47 -0.80 -2.88 -3.86 -3.45 -3.43 4.49 2.34 -12.95 -14.99 -14.06
None 5.83 8.31 7.90 4.19 -3.87 4.01 3.74 -0.27 -1.49 -1.39 5.68 8.85 7.95 3.20 -3.02
Nuclear Periphery 2.59 2.14 -2.78 -4.21 -3.95 1.54 0.69 -1.88 -2.49 -2.17 2.25 4.24 -3.62 -4.57 -5.13
Nuclear Periphery Foci 3.98 4.82 3.69 -0.65 -1.93 2.20 2.67 1.80 -0.80 -1.76 3.94 6.38 3.29 -0.92 -3.82
Nucleolus 0.96 3.15 -8.80 -9.74 -9.85 -1.13 -4.88 -2.62 -1.71 -1.12 -0.81 -1.00 -11.13 -10.04 -10.13
Nucleus -8.06 -4.86 12.11 19.96 13.58 1.43 5.73 5.90 4.78 4.57 -4.81 -4.14 17.43 20.63 20.78
Peroxisomes 1.79 -0.97 -6.73 -7.88 -3.81 -1.43 -1.75 -2.28 -2.03 -2.10 0.62 1.87 -8.15 -8.28 -8.99
Vacuole 3.07 -1.02 -1.75 -3.64 -1.14 -1.38 -0.63 -2.39 -2.14 -2.37 1.96 2.46 -3.29 -4.10 -4.25
Vacuole Periphery -1.02 0.76 -2.31 -1.91 -2.43 -0.74 0.88 -1.55 -1.11 -1.86 -0.72 1.14 -2.34 -1.98 -3.00
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that stimulates strand exchange; stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination
Localization
Cell Percentages nucleus (93%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Rad52

Rad52


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad52-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available