ORF
Human Ortholog
Description Putative protein of unknown function; has some characteristics of a transcriptional activator; may be a target of Dbf2p-Mob1p kinase; GFP-fusion protein co-localizes with clathrin-coated vesicles; YML037C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0.11 0.13 0.07 0.06 0 0 0 0 0 0 0 0.12 0.12 0 0 0.06 0.14 0.12 0.1 0.07 0.09 0.1 0.13
Bud 0.1 0 0.09 0.09 0.05 0.06 0.11 0.08 0.07 0.07 0.09 0.06 0 0.07 0 0 0.05 0.08 0 0 0 0 0 0
Bud Neck 0 0 0.07 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.25 0.38 0.43 0.47 0.59 0.39 0.31 0.32 0.26 0.37 0.24 0.32 0.48 0.54 0.57 0.43 0.46 0.45 0.05 0.09 0.07 0.1 0.1 0.1
Endoplasmic Reticulum 0.07 0.1 0.08 0 0 0 0 0 0 0 0 0 0.1 0 0 0.07 0.08 0 0 0 0 0 0 0
Endosome 0 0.11 0 0.05 0.07 0.06 0 0.06 0 0 0 0 0.1 0.14 0.28 0.2 0.21 0.22 0.25 0.19 0.15 0.15 0.16 0.16
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0 0 0 0.05
Mitochondria 0.7 0.27 0.09 0.19 0.1 0.51 0.64 0.56 0.74 0.58 0.81 0.55 0 0 0 0.05 0.09 0.11 0.33 0.34 0.48 0.4 0.42 0.37
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0.1 0 0 0 0.06 0 0.05 0 0 0.05
SpindlePole 0 0 0.21 0.19 0.15 0.11 0.09 0.14 0.11 0.13 0.06 0.17 0.17 0.14 0.15 0.18 0.14 0.1 0 0 0.05 0.06 0.06 0.05
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.06 0.05 0 0.08 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 12 17 17 9 9 0 4 1 0 1 6 0 28 38 2 12 11 30 40 25 15 27 45 60
Bud 25 6 11 12 8 11 30 17 26 18 31 16 9 21 3 2 9 16 5 8 2 6 9 8
Bud Neck 0 0 9 2 10 1 4 2 4 2 6 3 10 8 1 0 1 2 6 7 1 7 6 6
Bud Site 0 1 0 3 0 1 7 6 11 8 4 0 0 0 0 0 0 1 – – – – – –
Cell Periphery 1 1 4 2 1 1 1 2 2 0 3 4 0 1 0 9 7 4 0 0 0 0 1 2
Cytoplasm 60 60 56 63 92 66 82 66 94 91 84 83 110 172 229 143 86 96 15 22 15 30 46 49
Endoplasmic Reticulum 16 15 10 1 1 4 3 0 5 0 6 0 22 12 5 22 15 4 2 2 4 4 6 8
Endosome 7 17 3 6 11 11 4 13 4 1 1 9 23 45 114 66 39 47 80 47 31 43 75 76
Golgi 2 3 0 1 0 0 0 0 1 0 0 0 0 1 2 2 0 2 23 17 4 12 17 25
Mitochondria 169 42 11 25 15 87 167 117 272 144 286 141 10 7 2 16 16 24 106 83 100 118 196 176
Nucleus 1 0 2 0 3 1 1 8 6 3 1 2 0 0 0 5 1 3 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 0 0 1 1 1
Nucleolus 1 0 0 0 0 0 2 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 2 3 1 9 3 4 4 6 7 8 3 7 5 4 42 12 4 0 21 4 10 12 18 22
SpindlePole 5 3 27 25 23 18 24 29 42 33 20 43 38 44 62 58 26 22 9 4 11 17 29 24
Vac/Vac Membrane 4 8 4 2 3 5 4 4 4 2 4 7 2 8 8 53 11 10 8 18 6 5 12 9
Unique Cell Count 241 156 129 133 157 170 262 209 366 249 354 257 229 321 404 329 188 211 326 248 210 297 472 478
Labelled Cell Count 306 176 155 160 179 210 337 272 478 311 456 315 257 361 470 401 226 262 326 248 210 297 472 478


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 5.7 5.4 5.3 5.0 4.4 3.9 4.6 4.0 3.9 3.6 4.0 5.3 5.7 5.7 7.2 6.6 6.3 5.7 5.7 6.3
Std Deviation (1e-4) 0.5 0.8 1.2 2.0 1.4 1.7 1.4 1.4 1.5 1.1 0.9 1.1 0.9 0.9 1.3 1.2 1.2 1.2 1.5 1.1 1.7
Intensity Change (Log2) – – – -0.03 -0.11 -0.31 -0.46 -0.25 -0.45 -0.49 -0.59 -0.45 -0.02 0.06 0.07 0.42 0.29 0.22 0.07 0.06 0.21

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.7 -2.2 0 0 0 0 0 0 0 -0.3 -0.4 0 -3.8 -2.3 0.3
Bud 0.1 -1.2 0 0 0 0 0 0 0 -1.8 -0.7 0 0 -1.3 -0.3
Bud Neck -2.2 -0.2 0 0 0 0 0 0 0 -1.1 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.6 2.6 -0.8 -2.4 -2.2 -3.8 -1.3 -4.2 -2.1 0.8 2.0 2.6 0 0.4 0.4
Endoplasmic Reticulum -2.8 0 0 0 0 0 0 0 0 0.6 -1.8 0 -0.4 0.1 -2.6
Endosome 0 1.8 0 0 0 0 0 0 0 2.7 3.6 6.2 4.8 4.8 5.0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.4 0.3 0 0 0 0 0 0 0 -1.6 -3.1 0 -1.5 0 0.8
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 3.5 0 0 0
SpindlePole -0.4 -1.4 0 0 0 0 0 0 0 -1.0 -1.9 -1.5 -0.8 -1.7 -2.7
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 3.8 1.1 0.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.0298 0.3322 0.2057 -0.0993 0.1048 0.3111 0.4597 0.5163 0.5177 0.9396 0.6956 0.5621 0.18 0.4815 0.1782 0.7135 0.4192 0.3238
Actin 0.0047 0.0038 0.0181 0.0017 0.0036 0.0037 0.0196 0.0079 0.0219 0.0498 0.006 0.0092 0.0453 0.0165 0.0238 0.0385 0.0235 0.0143
Bud 0.0009 0.0066 0.0135 0.0011 0.0011 0.001 0.0068 0.0057 0.0067 0.0236 0.0019 0.003 0.0019 0.0067 0.0111 0.0008 0.0018 0.0018
Bud Neck 0.0006 0.0009 0.003 0.0029 0.0012 0.0083 0.004 0.0014 0.0108 0.0135 0.0028 0.0294 0.0042 0.0014 0.0083 0.0017 0.002 0.0274
Bud Periphery 0.0015 0.0048 0.0066 0.0015 0.0015 0.0011 0.0032 0.004 0.0137 0.0109 0.0019 0.0012 0.0028 0.0021 0.0115 0.0008 0.0029 0.0043
Bud Site 0.0019 0.0218 0.0169 0.0009 0.0005 0.0018 0.0153 0.0371 0.0224 0.009 0.0321 0.0014 0.0099 0.0332 0.0191 0.0014 0.0025 0.0011
Cell Periphery 0.0004 0.0007 0.0007 0.0002 0.0001 0.0003 0.0006 0.0009 0.0011 0.0005 0.0004 0.0002 0.0007 0.0006 0.0005 0.0002 0.0002 0.0002
Cytoplasm 0.1173 0.1834 0.1178 0.1659 0.1284 0.1473 0.104 0.1822 0.146 0.1639 0.1397 0.1414 0.1519 0.2062 0.1875 0.1776 0.1722 0.1351
Cytoplasmic Foci 0.1882 0.1919 0.2135 0.2132 0.1681 0.2431 0.253 0.2019 0.2182 0.1865 0.2909 0.3139 0.265 0.2468 0.2387 0.2055 0.2563 0.2786
Eisosomes 0.0003 0.0002 0.0005 0.0002 0.0001 0.0001 0.0007 0.0002 0.0004 0.0009 0.0001 0.0001 0.0005 0.0002 0.001 0.0002 0.0003 0.0001
Endoplasmic Reticulum 0.0038 0.0049 0.0035 0.0065 0.002 0.0031 0.005 0.0027 0.0048 0.004 0.0045 0.002 0.0074 0.0038 0.0044 0.0051 0.0036 0.0051
Endosome 0.2024 0.1563 0.1767 0.2717 0.135 0.167 0.1736 0.16 0.1622 0.1112 0.2635 0.1428 0.22 0.2249 0.2036 0.3418 0.2672 0.2768
Golgi 0.0263 0.0207 0.0399 0.0329 0.018 0.0246 0.0296 0.0334 0.0315 0.0302 0.0253 0.0302 0.0452 0.0468 0.0503 0.0457 0.0559 0.0563
Lipid Particles 0.0328 0.0128 0.016 0.023 0.0279 0.0252 0.0384 0.0061 0.0109 0.0088 0.0081 0.0096 0.0327 0.0168 0.0086 0.0079 0.0112 0.0107
Mitochondria 0.0141 0.0151 0.0427 0.0459 0.0091 0.0212 0.0102 0.0101 0.0536 0.0145 0.0147 0.0178 0.01 0.0121 0.023 0.0129 0.0267 0.024
None 0.3628 0.3265 0.2506 0.1594 0.4208 0.2732 0.2383 0.3063 0.2303 0.2901 0.1216 0.2016 0.1417 0.1275 0.1454 0.1061 0.0817 0.0952
Nuclear Periphery 0.0018 0.0037 0.0013 0.0038 0.0025 0.0024 0.0087 0.0008 0.004 0.006 0.0145 0.0029 0.0076 0.0011 0.0092 0.0022 0.0173 0.0021
Nucleolus 0.001 0.0014 0.0013 0.0006 0.001 0.0012 0.0015 0.0011 0.0021 0.0038 0.0029 0.0007 0.0009 0.0024 0.0015 0.0005 0.001 0.0008
Nucleus 0.0021 0.0037 0.0021 0.0032 0.0019 0.0024 0.0035 0.0035 0.0032 0.0135 0.013 0.01 0.0041 0.0045 0.0029 0.0013 0.0029 0.0024
Peroxisomes 0.0176 0.021 0.0619 0.0401 0.0528 0.0586 0.0556 0.0229 0.0384 0.0253 0.0323 0.0631 0.0308 0.0287 0.033 0.0302 0.0567 0.0489
Punctate Nuclear 0.0052 0.0065 0.0047 0.003 0.0084 0.0058 0.0211 0.0029 0.0038 0.0227 0.008 0.0129 0.0053 0.0045 0.0046 0.0028 0.0043 0.0055
Vacuole 0.0121 0.0113 0.0068 0.0166 0.0123 0.0066 0.0056 0.0078 0.0107 0.009 0.0112 0.0052 0.0095 0.0117 0.0095 0.0139 0.0051 0.0072
Vacuole Periphery 0.0022 0.0021 0.002 0.0058 0.0034 0.002 0.0017 0.0012 0.0031 0.0024 0.0045 0.0016 0.0025 0.0016 0.0027 0.003 0.0045 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.8537 2.8926 5.7238 5.2812 2.7969 11.858 5.8494 4.277 6.5259 6.3078
Translational Efficiency 1.2354 1.7093 0.8134 0.9886 1.874 0.639 1.0608 1.0015 0.9067 1.0103

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
333 1357 2270 971 1762 1220 1717 1659 2095 2577 3987 2630

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 706.03 747.96 821.51 815.17 673.62 759.57 864.67 705.79 678.77 753.46 840.10 746.17
Standard Deviation 80.13 99.68 85.65 100.47 77.88 93.23 98.79 86.43 79.13 96.86 94.00 105.95
Intensity Change Log 2 — 0.083232 0.218549 0.207371 — 0.173248 0.360215 0.067304 — 0.127884 0.289456 0.140680

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001655 0.002231 0.009582 0.019676 0.001511 0.002308 0.006231 0.007630 0.001534 0.002267 0.008139 0.012077
Bud Neck 0.034791 0.013814 0.046769 0.019604 0.016798 0.018080 0.018633 0.035672 0.019658 0.015834 0.034652 0.029740
Bud Site 0.019027 0.032184 0.046363 0.062899 0.012470 0.024333 0.035358 0.037761 0.013512 0.028467 0.041624 0.047042
Cell Periphery 0.000848 0.000171 0.000108 0.000297 0.000126 0.000131 0.000186 0.000147 0.000241 0.000152 0.000142 0.000202
Cytoplasm 0.125381 0.108553 0.163156 0.186001 0.101249 0.126302 0.268367 0.140271 0.105085 0.116956 0.208465 0.157155
Cytoplasmic Foci 0.431146 0.442494 0.237206 0.241754 0.462635 0.433148 0.225392 0.348362 0.457630 0.438069 0.232118 0.309002
Eisosomes 0.000938 0.000252 0.000165 0.000281 0.000336 0.000273 0.000142 0.000230 0.000432 0.000262 0.000155 0.000249
Endoplasmic Reticulum 0.001087 0.001754 0.002497 0.006406 0.001236 0.001142 0.003843 0.000829 0.001213 0.001464 0.003077 0.002888
Endosome 0.061913 0.098027 0.056918 0.048985 0.068520 0.078112 0.041132 0.076744 0.067470 0.088599 0.050120 0.066495
Golgi 0.125179 0.125335 0.017037 0.010589 0.135400 0.128680 0.008683 0.025122 0.133776 0.126918 0.013439 0.019756
Lipid Particles 0.020966 0.014689 0.016923 0.018617 0.031847 0.017943 0.016486 0.020317 0.030118 0.016229 0.016735 0.019689
Mitochondria 0.085727 0.056018 0.021026 0.004395 0.063109 0.060771 0.004600 0.010030 0.066704 0.058268 0.013952 0.007950
Mitotic Spindle 0.004044 0.013145 0.097627 0.033529 0.009876 0.015922 0.072470 0.031009 0.008949 0.014459 0.086793 0.031939
None 0.000410 0.001426 0.000430 0.000640 0.000940 0.000542 0.002000 0.000665 0.000856 0.001008 0.001106 0.000656
Nuclear Periphery 0.000111 0.000138 0.001348 0.000609 0.000150 0.000115 0.001487 0.000302 0.000144 0.000127 0.001408 0.000416
Nuclear Periphery Foci 0.000319 0.000625 0.001303 0.005196 0.000308 0.000194 0.004739 0.001283 0.000310 0.000421 0.002783 0.002728
Nucleolus 0.000568 0.000770 0.001479 0.001005 0.000953 0.000402 0.002708 0.002072 0.000892 0.000596 0.002008 0.001678
Nucleus 0.010171 0.005526 0.039194 0.052133 0.009859 0.006577 0.086458 0.024541 0.009909 0.006023 0.059548 0.034728
Peroxisomes 0.053380 0.037704 0.135612 0.118271 0.060512 0.048116 0.082155 0.181348 0.059379 0.042633 0.112591 0.158060
Vacuole 0.016373 0.036285 0.103957 0.168205 0.018289 0.031072 0.117984 0.054291 0.017985 0.033817 0.109998 0.096348
Vacuole Periphery 0.005965 0.008860 0.001298 0.000910 0.003874 0.005837 0.000946 0.001372 0.004206 0.007429 0.001146 0.001202

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.07 -9.17 -9.69 -9.61 -5.02 -2.20 -6.48 -5.65 -4.64 -1.48 -2.84 -12.60 -10.87 -9.86 -3.63
Bud Neck 4.27 -2.43 3.34 -2.76 12.66 -0.69 -1.26 -6.99 -6.19 -6.34 2.40 -8.62 -4.44 -7.42 3.58
Bud Site -3.42 -6.11 -8.07 -6.20 -3.59 -5.19 -8.70 -9.61 -3.75 -1.59 -8.48 -13.71 -14.09 -6.32 -2.51
Cell Periphery 2.18 2.40 1.84 -2.92 -10.23 -0.21 -3.80 -1.13 -0.62 2.26 1.68 2.13 0.97 -1.94 -5.72
Cytoplasm 1.71 -3.90 -5.57 -9.77 -3.00 -3.88 -21.58 -6.67 -2.38 14.36 -2.41 -19.75 -10.23 -8.16 8.11
Cytoplasmic Foci -0.92 16.80 16.38 26.79 1.06 3.86 38.32 15.57 10.24 -20.03 3.27 44.36 25.29 22.80 -15.93
Eisosomes 4.32 4.93 4.27 -0.43 -6.90 2.17 9.36 4.77 2.15 -6.67 5.03 9.03 6.06 1.51 -8.85
Endoplasmic Reticulum -2.03 -6.24 -10.61 -8.66 -7.29 0.32 -11.13 2.17 1.08 14.36 -1.15 -11.19 -7.68 -5.72 1.86
Endosome -5.76 1.41 3.33 12.97 3.52 -2.46 10.83 -1.85 0.63 -11.70 -6.63 8.06 1.42 8.20 -6.66
Golgi 0.02 12.09 12.78 26.32 4.89 1.02 30.68 25.47 21.33 -10.44 1.37 32.04 29.69 32.57 -5.67
Lipid Particles 2.30 1.48 1.39 -1.14 0.10 5.73 7.78 4.87 -1.22 -2.81 7.40 7.92 5.71 -2.03 -2.19
Mitochondria 3.44 8.10 10.19 15.72 14.01 0.50 19.70 17.24 14.97 -5.50 2.31 18.62 20.62 21.14 6.74
Mitotic Spindle -2.51 -18.24 -5.73 -4.64 13.03 -2.51 -14.79 -8.09 -4.90 8.01 -3.29 -25.16 -10.01 -7.02 15.40
None -2.00 -0.39 -0.75 1.64 -0.62 1.97 -3.32 1.21 -1.44 6.32 -0.04 -0.90 1.25 1.09 3.96
Nuclear Periphery -0.82 -10.06 -11.17 -10.74 6.20 1.66 -10.91 -5.52 -6.57 9.65 0.82 -14.59 -11.10 -11.57 11.54
Nuclear Periphery Foci -1.40 -4.83 -7.87 -7.25 -6.03 3.06 -10.96 -7.86 -8.90 7.94 -1.14 -12.41 -10.38 -9.33 0.63
Nucleolus -0.78 -4.67 -1.75 -0.39 3.82 3.06 -5.52 -3.74 -6.07 2.15 1.54 -6.12 -3.47 -4.94 2.79
Nucleus 2.72 -13.55 -13.14 -15.88 -3.31 3.23 -23.10 -8.31 -10.57 17.68 4.63 -26.88 -15.26 -18.70 11.71
Peroxisomes 2.81 -10.63 -6.15 -10.67 3.51 3.26 -1.87 -18.41 -19.99 -16.10 5.87 -11.22 -18.42 -23.25 -9.31
Vacuole -7.03 -26.65 -26.36 -23.57 -11.85 -5.88 -28.86 -14.49 -8.70 17.26 -9.44 -40.17 -27.48 -22.02 3.53
Vacuole Periphery -2.84 6.58 7.17 11.27 3.36 -4.24 12.77 8.76 10.22 -2.45 -6.73 13.59 12.16 14.42 -0.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; has some characteristics of a transcriptional activator; may be a target of Dbf2p-Mob1p kinase; GFP-fusion protein co-localizes with clathrin-coated vesicles; YML037C is not an essential gene
Localization
Cell Percentages mitochondrion (25%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

YML037C

YML037C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yml037c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available