Standard name
Human Ortholog
Description Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0.06 0.07 0.05 0.08 0 0 0 0.06 0.05 0.07 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.99 0.96 0.92 0.85 0.87 – 0.71 0.71 0.65 0.67 0.99 0.99 0.99 0.98 0.98 0.97 0.96 0.95 0.95 0.96 0.93 0.96
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0.05 0 0.05 0 0 0 0 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.2 0.05 – 0.23 0.2 0.33 0.24 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 – 0.1 0.08 0.08 0.09 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 3 1 2 – 5 10 7 12 0 0 0 0 0 0 0 0 0 1 0 0
Bud 0 1 0 1 0 5 2 – 7 2 5 4 0 1 0 0 0 0 0 0 0 0 3 3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 6 2 14 16 2 13 – 18 25 17 35 9 20 21 17 10 16 0 0 0 0 0 0
Cytoplasm 126 169 66 344 426 237 398 – 223 262 207 294 330 658 874 295 198 217 128 166 81 268 500 591
Endoplasmic Reticulum 2 1 0 1 9 4 14 – 4 20 2 21 3 1 2 8 3 14 0 1 1 2 14 8
Endosome 0 0 0 1 1 1 2 – 2 0 4 3 0 0 0 0 0 0 0 0 0 0 2 1
Golgi 0 0 0 0 3 0 1 – 0 0 0 0 0 1 1 0 0 1 0 0 0 1 1 1
Mitochondria 0 0 0 6 11 56 22 – 71 73 105 106 0 0 0 0 5 2 0 0 0 1 2 2
Nucleus 1 1 0 0 0 1 3 – 3 4 4 3 0 0 0 2 0 1 1 0 0 0 0 0
Nuclear Periphery 0 1 0 0 0 0 0 – 0 0 0 2 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 1 0 – 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 1 1 1 0 1 0 0 0 0 0 0 0 0 1 0
Vac/Vac Membrane 0 0 1 9 17 12 25 – 30 31 26 40 0 3 2 6 1 5 1 2 0 1 3 1
Unique Cell Count 128 172 67 357 461 279 455 314 369 317 439 332 663 880 302 203 223 135 175 86 280 536 619
Labelled Cell Count 131 179 69 376 486 320 482 363 431 378 523 342 685 900 328 217 256 135 175 86 280 536 619


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.7 8.8 7.9 8.9 9.3 6.7 8.4 – 7.9 7.7 7.8 7.9 10.0 9.7 10.1 11.8 12.1 12.4 9.0 9.2 9.2
Std Deviation (1e-4) 1.0 1.2 1.4 1.4 1.5 1.7 1.5 – 1.6 1.7 1.6 1.5 1.5 1.6 1.4 2.2 2.5 2.7 1.6 1.6 1.7
Intensity Change (Log2) – – – 0.17 0.24 -0.24 0.09 – -0.0 -0.04 -0.02 -0.0 0.34 0.3 0.36 0.58 0.62 0.66 0.2 0.22 0.22

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.9 -1.9 -3.0 -2.7 – -4.8 -4.8 -5.4 -5.3 0.8 0.6 0.7 -0.4 -0.5 -0.6
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.0 0 – 4.3 4.0 5.5 4.5 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 2.2 0 0 2.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.3366 3.4877 3.1247 2.7007 2.5077 3.1135 2.8545 5.0283 4.2209 3.8732 3.3739 4.4679 4.907 6.9875 5.7599 5.5668 5.5903 5.7579
Actin 0.0065 0.001 0.0012 0.0007 0.0002 0.0003 0.0388 0.0005 0.0151 0.0001 0.0017 0.0001 0.0088 0.0006 0.0038 0.0003 0.0003 0.0002
Bud 0.0002 0.0004 0.0014 0.0014 0.0001 0.0001 0.0008 0.0001 0.0006 0.0004 0.0006 0 0.0001 0.0001 0.0003 0.0002 0.0001 0.0001
Bud Neck 0.0003 0.0001 0.0003 0.0074 0.0002 0.0006 0.0014 0.0001 0.0011 0.0002 0.001 0.0004 0.0003 0.001 0.0002 0.0003 0.0002 0.0005
Bud Periphery 0.0001 0.0001 0.0009 0.0009 0 0 0.001 0 0.0003 0 0.0005 0 0.0001 0.0001 0.0002 0.0001 0 0
Bud Site 0.0004 0.0006 0.001 0.0035 0.0001 0 0.0016 0.0003 0.0008 0.0001 0.0016 0 0.0004 0.0138 0.0005 0.0002 0.0001 0
Cell Periphery 0.0002 0.0001 0.0001 0.0001 0 0 0.0003 0.0001 0.0001 0 0.0001 0 0.0002 0.0012 0.0003 0 0 0
Cytoplasm 0.8911 0.9667 0.9374 0.8889 0.8932 0.9625 0.7977 0.9623 0.9292 0.9539 0.9228 0.9819 0.877 0.9512 0.9379 0.9411 0.9746 0.975
Cytoplasmic Foci 0.0094 0.0078 0.0094 0.0222 0.0217 0.0102 0.0287 0.0047 0.011 0.0122 0.0243 0.0043 0.0099 0.004 0.0098 0.0094 0.0062 0.0036
Eisosomes 0.0001 0 0 0 0 0 0.0004 0 0.0002 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0089 0.0015 0.0031 0.0034 0.0046 0.0031 0.0094 0.0049 0.0025 0.001 0.0015 0.0033 0.0181 0.0025 0.0045 0.0025 0.0015 0.0047
Endosome 0.0133 0.0063 0.0127 0.0221 0.056 0.0098 0.0339 0.008 0.0191 0.0181 0.0236 0.0048 0.0162 0.0024 0.0068 0.0206 0.0081 0.0061
Golgi 0.002 0.0006 0.0006 0.0014 0.0008 0.0003 0.008 0.0031 0.0026 0.0003 0.003 0.0002 0.0028 0.0003 0.0016 0.0012 0.0003 0.0008
Lipid Particles 0.002 0 0.0001 0.0002 0.0003 0.0001 0.009 0.0001 0.0027 0 0.0005 0 0.0031 0.0001 0.0004 0.0001 0 0
Mitochondria 0.0008 0.0002 0.0002 0.0006 0.0002 0.0002 0.0035 0.0002 0.0008 0.0001 0.0018 0.0002 0.0005 0.0001 0.0003 0.0004 0.0001 0.0019
None 0.0533 0.0121 0.026 0.0385 0.0104 0.0093 0.0314 0.0133 0.0058 0.0022 0.0086 0.0031 0.0509 0.0211 0.0278 0.0192 0.006 0.0056
Nuclear Periphery 0.0057 0.0003 0.0007 0.0012 0.0025 0.0007 0.0082 0.0005 0.0015 0.0006 0.0005 0.0003 0.0038 0.0002 0.0006 0.0006 0.0003 0.0002
Nucleolus 0.0001 0 0 0.0001 0 0 0.0005 0 0.0003 0 0.0001 0 0.0001 0 0 0 0 0
Nucleus 0.0014 0.0006 0.0009 0.0017 0.0016 0.001 0.003 0.0006 0.0013 0.0009 0.0011 0.0006 0.0012 0.0003 0.0006 0.0008 0.0004 0.0005
Peroxisomes 0.0001 0 0.0001 0.0005 0.0001 0.0001 0.0096 0 0.0015 0.0001 0.0018 0 0.002 0 0.0025 0.0001 0 0
Punctate Nuclear 0.0007 0.0001 0.0002 0.0008 0.0005 0.0003 0.0086 0.0001 0.0015 0.0002 0.0006 0 0.0012 0.0001 0.0004 0.0001 0.0001 0
Vacuole 0.0025 0.0011 0.0032 0.0035 0.0058 0.001 0.0029 0.001 0.0017 0.0081 0.0035 0.0006 0.003 0.0008 0.0013 0.0023 0.0014 0.0005
Vacuole Periphery 0.0006 0.0002 0.0005 0.0009 0.0014 0.0003 0.0012 0.0002 0.0005 0.0015 0.0008 0.0002 0.0005 0.0001 0.0002 0.0005 0.0003 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 41.4898 28.0676 31.2411 43.521 30.5314 26.8974 26.8588 32.1514 26.0668 42.0891
Translational Efficiency 2.7663 4.4705 3.203 1.6739 3.4207 4.3748 3.6938 2.9261 3.5219 3.0532

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1384 721 1508 1376 1537 2550 2325 1210 2921 3271 3833 2586

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 890.25 902.49 1123.10 1140.06 854.81 989.86 1113.59 1181.86 871.60 970.60 1117.33 1159.62
Standard Deviation 112.92 138.36 134.72 183.50 106.70 126.52 144.76 217.33 111.11 134.20 140.97 201.13
Intensity Change Log 2 — 0.019700 0.335204 0.356827 — 0.211621 0.381542 0.467383 — 0.116902 0.358089 0.412042

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000485 0.000484 0.000237 0.000622 0.000237 0.000178 0.000117 0.000583 0.000354 0.000246 0.000164 0.000603
Bud Neck 0.003572 0.001627 0.001172 0.001441 0.002121 0.002676 0.000797 0.002913 0.002808 0.002445 0.000945 0.002130
Bud Site 0.020710 0.023243 0.007342 0.021098 0.013667 0.013843 0.005700 0.024459 0.017004 0.015915 0.006346 0.022671
Cell Periphery 0.000195 0.000137 0.000057 0.000116 0.000128 0.000066 0.000044 0.000165 0.000159 0.000081 0.000049 0.000139
Cytoplasm 0.568914 0.716174 0.790230 0.835825 0.684304 0.760373 0.846143 0.793516 0.629631 0.750631 0.824145 0.816029
Cytoplasmic Foci 0.288921 0.157246 0.044707 0.036596 0.212416 0.118473 0.030432 0.030130 0.248665 0.127019 0.036048 0.033570
Eisosomes 0.000063 0.000017 0.000009 0.000005 0.000028 0.000015 0.000005 0.000008 0.000045 0.000016 0.000006 0.000006
Endoplasmic Reticulum 0.003523 0.002061 0.000999 0.000537 0.003110 0.000801 0.000215 0.000306 0.003306 0.001079 0.000523 0.000429
Endosome 0.020260 0.015478 0.004326 0.003706 0.011835 0.007568 0.001742 0.006346 0.015827 0.009311 0.002759 0.004942
Golgi 0.011752 0.006057 0.000422 0.003563 0.009935 0.005612 0.000299 0.005286 0.010796 0.005710 0.000347 0.004369
Lipid Particles 0.002914 0.002050 0.000939 0.001494 0.002188 0.000854 0.000403 0.001114 0.002532 0.001118 0.000614 0.001316
Mitochondria 0.003437 0.000865 0.000096 0.001191 0.001662 0.000901 0.000078 0.002338 0.002503 0.000893 0.000085 0.001728
Mitotic Spindle 0.002094 0.001236 0.003522 0.007168 0.001695 0.004759 0.002106 0.009916 0.001884 0.003982 0.002663 0.008454
None 0.000678 0.001316 0.000900 0.000351 0.001010 0.001788 0.001239 0.002626 0.000852 0.001684 0.001105 0.001415
Nuclear Periphery 0.000056 0.000118 0.000265 0.000126 0.000068 0.000045 0.000062 0.000198 0.000062 0.000061 0.000142 0.000160
Nuclear Periphery Foci 0.000681 0.001558 0.003570 0.002341 0.000656 0.000403 0.001226 0.001723 0.000668 0.000657 0.002148 0.002052
Nucleolus 0.000233 0.000454 0.000112 0.000125 0.000263 0.000235 0.000128 0.000434 0.000249 0.000283 0.000122 0.000270
Nucleus 0.009889 0.009066 0.031920 0.009445 0.010692 0.016168 0.028238 0.016368 0.010311 0.014603 0.029686 0.012684
Peroxisomes 0.001626 0.001831 0.000265 0.001028 0.000902 0.001223 0.000198 0.001678 0.001245 0.001357 0.000224 0.001332
Vacuole 0.054705 0.054538 0.108396 0.071739 0.038071 0.061789 0.080479 0.095094 0.045953 0.060191 0.091462 0.082667
Vacuole Periphery 0.005292 0.004445 0.000516 0.001481 0.005013 0.002230 0.000349 0.004800 0.005145 0.002718 0.000415 0.003034

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.00 2.11 -0.37 -0.30 -1.90 0.87 1.98 -2.69 -3.54 -4.37 1.75 3.20 -1.96 -3.24 -4.22
Bud Neck 6.00 7.50 7.31 0.74 -0.68 -1.77 5.88 -0.64 0.17 -2.62 1.47 9.94 2.40 1.32 -2.92
Bud Site -1.00 9.80 0.91 1.55 -5.84 -0.07 8.52 -3.39 -3.36 -7.87 1.06 13.29 -1.77 -2.46 -9.86
Cell Periphery 2.75 9.68 5.52 1.73 -5.33 9.37 13.26 -1.31 -5.61 -7.21 9.39 14.83 3.06 -4.90 -9.25
Cytoplasm -12.36 -19.78 -26.84 -8.41 -6.93 -9.78 -18.81 -8.98 -1.44 6.08 -19.14 -28.17 -24.38 -6.84 0.54
Cytoplasmic Foci 15.68 42.29 43.36 18.03 2.69 16.40 35.93 35.32 26.31 0.15 26.35 54.88 54.57 31.13 1.16
Eisosomes 10.96 14.98 16.25 5.32 7.17 7.31 13.86 11.71 8.44 -4.44 14.25 19.69 19.72 11.61 0.59
Endoplasmic Reticulum 2.40 5.25 6.16 4.06 2.06 5.02 6.67 6.55 3.63 -1.22 6.33 8.64 8.90 4.43 1.23
Endosome 2.72 16.04 16.26 7.98 1.88 5.48 14.88 7.21 3.47 -4.32 8.84 22.02 16.83 9.01 -3.16
Golgi 6.76 20.70 9.31 3.30 -2.69 6.47 17.57 6.04 2.04 -3.67 9.97 26.92 10.77 3.80 -4.50
Lipid Particles 2.25 8.61 3.90 1.27 -1.62 6.97 9.69 3.46 -3.17 -6.19 8.65 13.30 4.94 -1.60 -4.40
Mitochondria 2.34 3.26 2.24 0.03 -1.43 2.07 4.50 0.14 -1.17 -2.65 3.02 4.65 2.03 -0.73 -2.86
Mitotic Spindle 1.03 -2.14 -2.57 -3.21 -1.01 -2.60 -0.33 -2.79 -1.10 -2.64 -2.34 -1.58 -3.81 -1.91 -2.85
None -1.48 -0.68 1.22 3.01 8.11 -4.04 -0.79 -1.37 -0.20 -1.22 -4.01 -1.07 -0.66 1.74 -0.20
Nuclear Periphery -1.70 -7.52 -1.47 0.09 3.94 1.24 -0.94 -1.76 -2.18 -1.56 0.01 -6.84 -2.26 -2.27 0.84
Nuclear Periphery Foci -4.12 -8.58 -5.94 -2.31 3.16 1.65 -6.22 -6.24 -6.84 -2.93 -0.25 -10.34 -8.43 -7.67 0.46
Nucleolus -0.93 1.14 1.11 1.56 -0.24 0.34 1.53 -0.68 -1.14 -2.09 -0.41 1.85 0.24 0.76 -2.05
Nucleus 0.62 -17.15 -1.94 -2.29 17.06 -6.62 -20.69 -8.14 -2.70 9.08 -5.88 -26.43 -7.20 -0.88 19.23
Peroxisomes -0.48 10.95 2.70 1.97 -2.47 -2.19 10.19 -1.33 -0.23 -3.86 -0.73 14.92 0.84 1.19 -4.55
Vacuole -0.14 -15.93 -9.99 -7.97 6.60 -9.62 -16.76 -14.56 -10.25 -4.08 -6.86 -22.44 -17.85 -13.04 0.87
Vacuole Periphery 0.88 6.87 5.16 4.11 -1.59 4.81 8.30 1.81 -1.29 -3.73 5.04 10.67 4.91 1.27 -4.05
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Gim5

Gim5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gim5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available