Standard name
Human Ortholog
Description Single-stranded DNA endonuclease (with Rad1p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.21 0.12 0.12 0.18 0.23 0.34 0.29 – 0.19 0.16 0.12 0.18 0.3 0.29 0.27 0.15 0.3 0.26 0.1 0.12 0.17 0.15 0.11 0.16
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0.05 0 0 – 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0
Golgi 0 0 0 0.06 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.07 0.18 0.24 0 0.49 0.16 – 0.57 0.43 0.53 0.35 0 0 0 0.06 0 0 0 0 0 0 0 0.05
Nucleus 0.55 0.55 0.59 0.53 0.52 0.34 0.45 – 0.4 0.5 0.49 0.48 0.42 0.41 0.45 0.29 0.27 0.3 0.57 0.67 0.57 0.49 0.5 0.36
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.32 0.43 0.18 0.18 0.24 0.06 0.16 – 0.11 0.12 0.11 0.13 0.37 0.37 0.33 0.6 0.5 0.5 0.24 0.13 0.15 0.23 0.27 0.26
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 1
Bud 0 0 0 0 0 0 0 – 0 0 1 1 0 0 0 0 0 0 1 1 0 3 7 11
Bud Neck 0 0 0 0 0 1 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 4
Bud Site 0 0 0 0 0 0 0 – 0 2 3 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 42 20 2 3 19 28 60 – 29 30 19 36 52 85 88 19 26 28 24 21 6 32 38 54
Endoplasmic Reticulum 1 2 0 0 0 0 0 – 0 0 0 0 0 0 0 10 3 5 0 0 0 0 0 4
Endosome 2 2 0 0 4 0 6 – 4 1 1 4 4 11 16 7 2 0 3 1 0 4 6 4
Golgi 1 0 0 1 0 1 0 – 0 0 0 0 0 1 0 0 3 2 2 0 0 0 1 2
Mitochondria 6 12 3 4 3 40 32 – 86 79 81 69 0 0 1 8 2 1 2 4 1 5 6 16
Nucleus 108 89 10 9 43 28 92 – 60 92 75 94 72 119 149 37 24 33 136 120 22 109 172 123
Nuclear Periphery 0 1 0 0 0 0 0 – 0 0 1 1 0 0 0 0 0 2 0 0 0 0 1 2
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 2 0 0 0 2 0 0 1 0 0 2 2 4
Peroxisomes 0 0 0 0 0 0 1 – 0 0 0 1 0 0 0 1 0 0 1 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 2 – 1 2 0 2 0 1 2 1 0 1 4 1 1 6 8 14
Vac/Vac Membrane 64 69 3 3 20 5 33 – 17 23 17 25 63 109 108 76 44 54 58 24 5 51 92 90
Unique Cell Count 198 161 17 17 82 82 204 150 184 153 195 172 292 332 127 88 109 240 181 39 223 345 344
Labelled Cell Count 224 195 18 20 90 103 226 197 230 199 238 191 327 364 161 104 126 240 181 39 223 345 344


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.8 5.2 4.3 4.7 5.3 3.7 4.9 – 4.5 4.4 4.2 4.6 5.6 5.8 5.8 6.2 6.8 6.4 4.9 5.2 5.6
Std Deviation (1e-4) 0.7 1.2 0.5 1.7 0.9 1.3 2.2 – 2.4 1.5 1.3 2.3 1.5 1.4 1.3 1.6 1.7 1.8 1.1 1.6 1.7
Intensity Change (Log2) – – – 0.11 0.29 -0.25 0.16 – 0.04 0.01 -0.04 0.07 0.38 0.42 0.41 0.52 0.65 0.56 0.19 0.25 0.35


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 1.8 0 – 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus -0.3 -0.5 -1.9 -1.1 – -1.5 -0.7 -0.8 -0.8 -1.3 -1.5 -1.1 -2.5 -2.5 -2.3
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 1.6 1.6 1.3 3.3 2.5 2.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.603 -0.1351 -0.4313 -0.5543 -0.9142 -0.6077 0.7436 1.3223 1.1021 0.4218 0.5724 0.9542 2.3545 2.5362 2.3113 2.3747 2.2328 2.5601
Actin 0.0224 0.0004 0.0078 0.0003 0.0036 0.0006 0.0054 0.0001 0.0133 0.0001 0.0327 0.0031 0.0078 0.0001 0.0066 0.0002 0.0098 0.0041
Bud 0.0003 0.0089 0.0012 0 0.0001 0.0001 0.0003 0.0001 0.0003 0.0001 0.0009 0.0009 0.0008 0.0001 0.001 0.0001 0.0004 0.0002
Bud Neck 0.0036 0.0005 0.0007 0.0006 0.0005 0.0025 0.0009 0.0003 0.0006 0.0007 0.0011 0.0031 0.0085 0.0005 0.0011 0.0003 0.0008 0.0097
Bud Periphery 0.0005 0.0013 0.0003 0 0.0001 0.0001 0.0004 0.0001 0.0005 0 0.0019 0.0009 0.0013 0 0.0022 0 0.0005 0.0002
Bud Site 0.0029 0.0023 0.0043 0.0002 0.0002 0.0002 0.0013 0.0008 0.0013 0.0004 0.0014 0.0012 0.0078 0.0006 0.0023 0.0003 0.0007 0.0019
Cell Periphery 0.0002 0.0001 0.0001 0 0 0 0.0005 0.0001 0.0002 0 0.0001 0.0001 0.0005 0 0.0003 0 0 0
Cytoplasm 0.1048 0.1497 0.0924 0.17 0.0774 0.0951 0.0596 0.1966 0.1205 0.0488 0.1184 0.0971 0.1013 0.1293 0.0771 0.125 0.0817 0.1193
Cytoplasmic Foci 0.0244 0.0026 0.0126 0.0022 0.0048 0.0117 0.0239 0.001 0.0098 0.0006 0.0124 0.006 0.0094 0.0033 0.0079 0.0008 0.0031 0.0045
Eisosomes 0.0002 0 0.0001 0 0.0001 0 0.0001 0 0.0001 0 0.0004 0 0.0001 0 0.0002 0 0 0
Endoplasmic Reticulum 0.0066 0.0088 0.0041 0.0049 0.0026 0.0027 0.013 0.0055 0.0026 0.0006 0.0035 0.0043 0.0047 0.003 0.0023 0.0018 0.0035 0.0025
Endosome 0.0215 0.012 0.0067 0.0051 0.0273 0.0079 0.0186 0.0022 0.0109 0.0009 0.03 0.0182 0.0279 0.0045 0.0047 0.001 0.0085 0.0042
Golgi 0.0047 0.0001 0.0035 0.0001 0.0182 0.003 0.0125 0 0.006 0 0.0099 0.0046 0.0057 0.0001 0.0028 0 0.0031 0.0013
Lipid Particles 0.0078 0.0005 0.0062 0.0002 0.0223 0.0013 0.0065 0.0001 0.007 0 0.013 0.0048 0.0092 0.0003 0.0049 0 0.0015 0.0011
Mitochondria 0.0048 0.0012 0.0079 0.0005 0.0025 0.0006 0.0139 0.0004 0.0188 0.0005 0.0978 0.0027 0.0103 0.0003 0.0092 0.0006 0.0046 0.0007
None 0.0768 0.0986 0.1242 0.0917 0.0461 0.0542 0.0058 0.041 0.0738 0.005 0.0385 0.051 0.0516 0.0405 0.1181 0.0556 0.1043 0.1173
Nuclear Periphery 0.034 0.046 0.0431 0.0267 0.0153 0.0226 0.0114 0.0202 0.0161 0.0091 0.0163 0.0136 0.0311 0.0207 0.0172 0.0151 0.024 0.0078
Nucleolus 0.0024 0.0039 0.0029 0.0023 0.0022 0.0037 0.0014 0.0017 0.0025 0.0042 0.0036 0.002 0.0043 0.0022 0.0042 0.0018 0.0051 0.0042
Nucleus 0.64 0.6176 0.6407 0.6546 0.7613 0.7523 0.8053 0.7188 0.6942 0.9177 0.5835 0.7571 0.6902 0.7782 0.7072 0.7923 0.7202 0.6977
Peroxisomes 0.016 0.0001 0.0072 0.0001 0.0017 0.0001 0.0041 0 0.0033 0 0.0148 0.0013 0.0034 0.0001 0.0046 0 0.0112 0.0017
Punctate Nuclear 0.022 0.0395 0.0316 0.0378 0.0117 0.0393 0.0124 0.0075 0.0103 0.0105 0.0163 0.0231 0.0148 0.0135 0.0233 0.0035 0.0123 0.0198
Vacuole 0.0031 0.0047 0.0018 0.0021 0.0014 0.0015 0.0021 0.0031 0.0063 0.0006 0.0021 0.0031 0.007 0.0024 0.0021 0.0011 0.0029 0.0015
Vacuole Periphery 0.001 0.0011 0.0007 0.0004 0.0006 0.0003 0.0007 0.0004 0.0017 0.0002 0.0012 0.0017 0.002 0.0003 0.0008 0.0003 0.0015 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.3578 4.6748 6.9378 6.8123 3.3901 5.2265 3.1511 6.912 4.9957 5.1897
Translational Efficiency 1.6673 1.6195 1.0705 1.4794 2.636 2.0294 2.8472 1.8496 2.1536 2.1692

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
318 1384 1261 1823 1616 2130 213 1667 1934 3514 1474 3490

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 713.28 744.48 925.05 846.31 685.82 785.46 884.48 905.93 690.34 769.32 919.19 874.79
Standard Deviation 80.82 106.08 117.84 122.43 79.33 103.78 131.56 138.70 80.23 106.59 120.76 133.81
Intensity Change Log 2 — 0.061765 0.375063 0.246718 — 0.195708 0.367000 0.401570 — 0.128976 0.371116 0.324701

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000113 0.000522 0.000374 0.000656 0.000075 0.000295 0.000808 0.002156 0.000081 0.000384 0.000437 0.001373
Bud Neck 0.003394 0.011977 0.005123 0.009196 0.002675 0.013057 0.001996 0.014833 0.002793 0.012632 0.004671 0.011889
Bud Site 0.001747 0.007680 0.002280 0.014445 0.001301 0.008148 0.010969 0.017019 0.001375 0.007964 0.003536 0.015675
Cell Periphery 0.000336 0.000174 0.000097 0.000206 0.000097 0.000168 0.000194 0.000146 0.000136 0.000170 0.000111 0.000177
Cytoplasm 0.119790* 0.257274* 0.060895 0.184866* 0.245142* 0.219719* 0.084427 0.182189* 0.224531* 0.234511* 0.064295 0.183587*
Cytoplasmic Foci 0.025489 0.048717 0.000369 0.002910 0.037895 0.023576 0.006703 0.002444 0.035855 0.033478 0.001284 0.002687
Eisosomes 0.000060 0.000050 0.000016 0.000028 0.000036 0.000030 0.000073 0.000025 0.000040 0.000038 0.000024 0.000026
Endoplasmic Reticulum 0.002395 0.005202 0.005066 0.004703 0.000938 0.001742 0.009226 0.004904 0.001177 0.003105 0.005667 0.004799
Endosome 0.001200 0.004537 0.000467 0.002984 0.001224 0.003435 0.001955 0.001899 0.001220 0.003869 0.000682 0.002466
Golgi 0.000155 0.002197 0.000048 0.001723 0.000221 0.001466 0.000110 0.003024 0.000211 0.001754 0.000057 0.002344
Lipid Particles 0.003266 0.004654 0.000268 0.000924 0.002969 0.002321 0.002553 0.000550 0.003018 0.003240 0.000598 0.000746
Mitochondria 0.002410 0.009035 0.000837 0.004184 0.001832 0.005454 0.000569 0.004335 0.001927 0.006864 0.000798 0.004256
Mitotic Spindle 0.001923 0.005431 0.002003 0.027718 0.000730 0.011403 0.000165 0.024479 0.000926 0.009051 0.001737 0.026171
None 0.006618 0.012198 0.003883 0.014306 0.007485 0.008371 0.009670 0.009994 0.007343 0.009878 0.004719 0.012246
Nuclear Periphery 0.000797 0.001912 0.001495 0.002684 0.001247 0.001794 0.001640 0.002564 0.001173 0.001841 0.001516 0.002627
Nuclear Periphery Foci 0.000572 0.001800 0.000374 0.001569 0.000472 0.000851 0.003179 0.000977 0.000488 0.001225 0.000779 0.001286
Nucleolus 0.006801 0.004175 0.000415 0.001145 0.002341 0.004351 0.002111 0.000904 0.003075 0.004282 0.000660 0.001030
Nucleus 0.812534* 0.598323* 0.907870* 0.697768* 0.685871* 0.679064* 0.833008* 0.700730* 0.706697* 0.647264* 0.897052* 0.699183*
Peroxisomes 0.003076 0.005768 0.000058 0.000258 0.001276 0.002889 0.000487 0.000659 0.001572 0.004023 0.000120 0.000449
Vacuole 0.007028 0.016596 0.007945 0.026437 0.005994 0.010699 0.029980 0.023858 0.006164 0.013022 0.011129 0.025205
Vacuole Periphery 0.000295 0.001777 0.000118 0.001290 0.000181 0.001167 0.000178 0.002311 0.000200 0.001407 0.000127 0.001778

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.20 -10.31 -9.63 -1.57 -2.75 -3.10 -7.46 -2.41 -1.94 -0.16 -6.17 -12.86 -3.86 -2.40 -1.47
Bud Neck -5.43 -2.86 -7.90 -0.26 -5.27 -8.41 -1.28 -10.99 -1.63 -10.43 -10.46 -4.79 -15.21 -1.22 -8.12
Bud Site -5.48 -1.64 -6.54 -1.70 -5.36 -5.98 -1.48 -6.81 -1.47 -0.50 -7.75 -2.54 -9.25 -2.17 -5.50
Cell Periphery 2.49 3.66 2.96 2.09 -3.83 -3.77 -4.99 -3.84 2.21 3.57 -2.19 1.19 -0.22 2.60 -2.07
Cytoplasm -10.62 5.76 -1.38 14.89 -15.27 3.10 16.18 14.80 12.37 -6.26 -1.40 27.16 14.43 19.05 -18.15
Cytoplasmic Foci -4.22 6.31 5.99 16.93 -6.28 5.63 12.36 16.95 14.30 1.85 1.34 18.29 18.01 21.97 -2.37
Eisosomes 1.34 6.18 3.15 3.13 -9.34 2.72 -5.40 -0.23 -3.42 5.38 0.60 2.83 0.40 -0.32 -3.05
Endoplasmic Reticulum -5.80 -9.37 -11.04 -3.79 -0.04 -4.96 -10.81 -19.40 -16.18 4.37 -10.04 -18.13 -26.90 -15.16 1.33
Endosome -5.95 2.11 -1.69 4.92 -4.40 -5.01 -2.71 -0.60 4.64 2.36 -7.58 1.99 -1.67 6.50 -3.94
Golgi -4.21 3.75 -1.49 2.91 -1.94 -2.79 0.96 -1.41 0.55 -1.55 -4.61 2.20 -1.86 2.05 -2.35
Lipid Particles -2.17 6.59 5.27 8.36 -5.11 1.32 0.78 5.79 5.41 4.24 -0.63 7.00 6.61 9.56 -1.66
Mitochondria -4.06 1.36 -0.57 4.45 -4.40 -4.70 2.05 -1.86 3.29 -5.21 -6.46 1.99 -2.03 5.55 -6.45
Mitotic Spindle -1.17 -0.52 -6.53 -6.98 -8.00 -6.11 -1.52 -8.01 -2.87 -4.83 -6.54 -3.06 -11.94 -6.42 -9.86
None -3.33 2.59 -2.30 1.37 -6.57 -0.71 0.62 -0.58 0.27 -1.09 -2.42 3.77 -1.90 0.80 -7.88
Nuclear Periphery -6.79 -10.79 -18.30 -10.68 -11.87 -2.12 -3.70 -12.50 -9.34 -8.38 -3.40 -5.06 -16.59 -13.63 -15.59
Nuclear Periphery Foci -3.28 -0.34 -3.01 -0.22 -2.94 -1.37 -2.08 -3.11 -2.26 1.74 -3.78 -2.32 -4.52 -1.87 -0.36
Nucleolus 1.37 2.84 2.15 3.56 -4.19 -2.85 1.40 1.87 4.65 0.39 -1.55 4.71 2.36 5.46 -4.66
Nucleus 12.47 -6.15 4.94 -12.27 21.81 0.76 -6.77 -5.59 -6.47 3.83 7.09 -22.83 -3.62 -12.43 23.43
Peroxisomes -1.88 2.62 2.53 6.61 -4.56 -3.07 2.83 3.01 6.16 0.68 -4.57 4.76 4.26 9.09 -2.00
Vacuole -2.99 -2.31 -11.30 -11.72 -11.37 -4.98 -7.05 -16.51 -14.07 1.60 -7.57 -8.15 -22.61 -18.61 -10.40
Vacuole Periphery -3.67 2.72 -1.35 3.05 -2.78 -4.02 -0.15 -2.55 0.68 -2.54 -5.58 2.32 -3.20 2.67 -3.63
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Single-stranded DNA endonuclease (with Rad1p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein
Localization
Cell Percentages nucleus (42%), cytoplasm (3%), mixed (49%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rad10

Rad10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available