Standard name
Human Ortholog
Description Constituent of 66S pre-ribosomal particles; forms a complex with Nop7p and Ytm1p that is required for maturation of the large ribosomal subunit; required for maturation of the 25S and 5.8S ribosomal RNAs; homologous to mammalian Bop1
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 0.98 0.99 0.98 0.99 0.98 0.94 – 0.81 0.84 0.71 0.86 0.99 0.99 1.0 0.98 0.96 0.97 0.95 0.92 0.89 0.9 0.87 0.86
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.12 – 0.32 0.23 0.44 0.25 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 1 0 1 1 2 2
Bud 0 3 0 0 0 1 2 – 3 3 2 4 1 0 2 0 0 0 0 0 1 1 3 11
Bud Neck 0 0 2 0 4 0 3 – 2 1 0 1 0 0 0 0 0 0 1 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 2 3 0 2 1 2 – 7 5 2 4 0 0 0 4 3 7 0 0 0 0 0 0
Cytoplasm 200 285 238 126 274 250 365 – 240 281 177 236 284 382 356 300 256 193 190 272 220 182 254 314
Endoplasmic Reticulum 0 1 0 0 0 1 3 – 2 3 3 0 0 0 0 12 15 8 0 0 2 0 3 4
Endosome 0 0 0 0 0 0 1 – 0 0 0 0 0 0 0 1 1 1 1 5 2 0 1 2
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 1 0 0 0 2 1 1
Mitochondria 2 6 1 5 1 13 45 – 94 77 110 69 2 2 1 8 4 0 2 5 6 6 10 10
Nucleus 0 0 2 0 0 1 6 – 3 4 5 1 0 0 0 1 0 2 0 0 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1
SpindlePole 0 0 0 0 0 0 0 – 0 2 0 3 1 0 0 0 1 0 0 0 2 1 1 1
Vac/Vac Membrane 0 2 1 0 0 0 3 – 3 4 3 1 0 0 0 6 7 3 0 5 2 2 5 6
Unique Cell Count 200 292 240 128 277 254 387 295 335 251 275 286 384 357 307 267 198 200 295 248 202 292 364
Labelled Cell Count 204 300 247 131 281 267 431 354 381 303 319 288 385 360 332 287 215 200 295 248 202 292 364


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 4.3 5.0 4.4 5.3 4.2 4.5 – 3.9 3.9 3.5 4.1 4.7 4.7 4.9 6.3 6.5 6.3 4.4 4.6 4.8
Std Deviation (1e-4) 0.4 0.7 1.1 1.0 1.3 0.8 1.1 – 0.7 0.8 0.8 0.7 1.1 1.1 1.3 0.8 1.3 1.0 1.2 1.3 1.5
Intensity Change (Log2) – – – -0.19 0.08 -0.25 -0.18 – -0.39 -0.39 -0.52 -0.29 -0.11 -0.09 -0.05 0.31 0.37 0.32 -0.2 -0.14 -0.06


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.6537 2.3765 2.3131 2.7929 2.7376 2.4377 -0.6495 -0.1097 -0.0846 -0.0386 -0.3674 -0.2699 -0.7994 -0.0852 -0.1443 0.1073 -0.4755 -0.3489
Actin 0.0224 0.001 0.0114 0.0253 0.0027 0.0068 0.0321 0.0016 0.0234 0.0021 0.0014 0.0039 0.0032 0.0001 0.0188 0.0011 0.0004 0.0003
Bud 0.0017 0.0015 0.0028 0.001 0.0022 0.0006 0.0065 0.0058 0.0035 0.0016 0.0002 0.0007 0.0007 0 0.0009 0.0004 0 0
Bud Neck 0.0133 0.0007 0.0005 0.0049 0.0438 0.0073 0.0064 0.0004 0.0006 0.0014 0.0003 0.0005 0.0002 0 0.0087 0.0005 0.0139 0.0007
Bud Periphery 0.0044 0.0025 0.0062 0.0019 0.0044 0.0004 0.0097 0.0122 0.0059 0.0025 0.0003 0.0014 0.0006 0 0.0025 0.0004 0 0
Bud Site 0.014 0.0294 0.0033 0.0045 0.0025 0.001 0.0084 0.0148 0.0089 0.0009 0.0005 0.0009 0.0008 0.0001 0.0033 0.0035 0 0
Cell Periphery 0.0012 0.0007 0.0002 0.001 0.0005 0.0001 0.0004 0.0007 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0
Cytoplasm 0.0624 0.124 0.0914 0.0684 0.1669 0.2011 0.2086 0.3616 0.3104 0.3557 0.2701 0.4156 0.239 0.4294 0.4132 0.4762 0.364 0.4746
Cytoplasmic Foci 0.0191 0.006 0.009 0.0072 0.036 0.0093 0.0197 0.0098 0.0152 0.0406 0.0269 0.0116 0.034 0.0047 0.0174 0.0078 0.0038 0.0045
Eisosomes 0.0006 0.0003 0.0002 0.0003 0.0001 0.0001 0.0004 0.0001 0.0002 0.0001 0 0.0001 0 0 0.0003 0 0 0
Endoplasmic Reticulum 0.0028 0.0008 0.0074 0.0007 0.0079 0.0012 0.0051 0.0015 0.002 0.0012 0.0011 0.0013 0.0023 0.0007 0.0011 0.0014 0.0039 0.0043
Endosome 0.0114 0.0009 0.0125 0.0069 0.0409 0.0036 0.0194 0.0017 0.0094 0.0264 0.0256 0.0054 0.0138 0.0015 0.0047 0.0024 0.0016 0.0015
Golgi 0.0094 0.0003 0.007 0.0148 0.0055 0.0023 0.007 0.0003 0.0077 0.0032 0.0085 0.0024 0.002 0.0001 0.0025 0.0003 0.0001 0.0001
Lipid Particles 0.0137 0.0004 0.0053 0.0156 0.0027 0.0011 0.0056 0.0002 0.0025 0.0039 0.007 0.003 0.0045 0.0001 0.005 0.0002 0.0001 0.0001
Mitochondria 0.0107 0.0006 0.0166 0.0239 0.0608 0.0027 0.0056 0.0009 0.0209 0.001 0.0143 0.0042 0.0009 0.0001 0.0016 0.0002 0.0006 0.0008
None 0.7651 0.8257 0.8048 0.7976 0.5927 0.7497 0.637 0.5759 0.5795 0.5463 0.6073 0.5386 0.6699 0.5616 0.5035 0.5012 0.5594 0.4982
Nuclear Periphery 0.0033 0.0004 0.0027 0.0004 0.0091 0.0056 0.0053 0.0006 0.0009 0.0012 0.0071 0.0013 0.0051 0.0002 0.0009 0.0006 0.0085 0.002
Nucleolus 0.0021 0.0002 0.0006 0.0043 0.0036 0.0001 0.0008 0.0004 0.0003 0.0002 0.0004 0.0003 0.0006 0 0.0028 0.0001 0.0005 0.0002
Nucleus 0.0171 0.0009 0.0013 0.0007 0.0057 0.0022 0.0031 0.0034 0.0013 0.0019 0.0037 0.0028 0.0049 0.0005 0.0025 0.0012 0.0415 0.0106
Peroxisomes 0.0131 0.0007 0.0124 0.0128 0.0029 0.0029 0.0071 0.0048 0.0034 0.0054 0.0142 0.0018 0.0033 0 0.0057 0.0001 0 0.0001
Punctate Nuclear 0.008 0.0021 0.0021 0.0004 0.0023 0.0011 0.0085 0.0015 0.0015 0.0029 0.0088 0.0032 0.0058 0.0002 0.0033 0.001 0.0007 0.0013
Vacuole 0.0032 0.0009 0.0016 0.0063 0.0052 0.0005 0.0021 0.0016 0.0018 0.0011 0.0014 0.0007 0.0058 0.0005 0.001 0.0012 0.0007 0.0004
Vacuole Periphery 0.0008 0.0001 0.0007 0.001 0.0015 0.0003 0.0012 0.0002 0.0006 0.0003 0.0007 0.0002 0.0023 0.0001 0.0003 0.0002 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 84.4396 87.0811 78.8097 57.0495 59.9039 52.774 56.1612 45.125 37.0355 55.1776
Translational Efficiency 2.2129 2.2622 1.706 1.899 1.918 2.0204 1.8029 1.5712 1.5808 1.6758

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1952 953 509 1459 1335 125 211 772 3287 1078 720 2231

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 685.03 777.33 907.81 869.72 716.56 805.13 935.29 872.39 697.84 780.55 915.86 870.64
Standard Deviation 70.24 95.75 100.04 101.80 81.80 81.08 101.87 105.97 76.73 94.59 101.35 103.27
Intensity Change Log 2 — 0.182360 0.406223 0.344384 — 0.168134 0.384326 0.283886 — 0.175105 0.395070 0.313771

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000212 0.000404 0.000904 0.000413 0.000143 0.000193 0.000208 0.001516 0.000184 0.000379 0.000700 0.000795
Bud Neck 0.013071 0.018294 0.003683 0.005782 0.007068 0.029935 0.001329 0.004689 0.010633 0.019644 0.002993 0.005404
Bud Site 0.005139 0.015491 0.006318 0.035861 0.003683 0.011944 0.001825 0.030222 0.004548 0.015079 0.005001 0.033910
Cell Periphery 0.000120 0.000133 0.000196 0.000135 0.000123 0.000155 0.000206 0.000143 0.000121 0.000135 0.000199 0.000138
Cytoplasm 0.595548* 0.511384* 0.236013* 0.548407* 0.564808* 0.331706* 0.324290* 0.519468* 0.583063* 0.490550* 0.261883* 0.538393*
Cytoplasmic Foci 0.169366 0.235242* 0.006250 0.020834 0.226979* 0.301052* 0.039257 0.029531 0.192766* 0.242873* 0.015923 0.023844
Eisosomes 0.000131 0.000110 0.000064 0.000039 0.000121 0.000148 0.000120 0.000054 0.000127 0.000114 0.000080 0.000044
Endoplasmic Reticulum 0.000617 0.000567 0.010185 0.001798 0.000599 0.000623 0.003408 0.001794 0.000610 0.000574 0.008199 0.001797
Endosome 0.009089 0.021570 0.002819 0.007263 0.009484 0.044660 0.007226 0.006588 0.009249 0.024247 0.004110 0.007030
Golgi 0.001426 0.004132 0.000106 0.002986 0.001958 0.008114 0.000091 0.001362 0.001642 0.004594 0.000102 0.002424
Lipid Particles 0.004469 0.003759 0.002075 0.001274 0.005262 0.009636 0.003811 0.001128 0.004791 0.004440 0.002583 0.001224
Mitochondria 0.003696 0.004026 0.000653 0.002793 0.002351 0.014679 0.000210 0.010515 0.003149 0.005261 0.000523 0.005465
Mitotic Spindle 0.001657 0.005037 0.002937 0.042268 0.001222 0.008875 0.000410 0.024840 0.001480 0.005482 0.002197 0.036237
None 0.004338 0.002256 0.004297 0.004577 0.002187 0.000936 0.003127 0.008909 0.003465 0.002103 0.003954 0.006076
Nuclear Periphery 0.000262 0.000263 0.002108 0.001412 0.000316 0.000561 0.001734 0.000945 0.000284 0.000298 0.001998 0.001250
Nuclear Periphery Foci 0.000348 0.000662 0.002196 0.001578 0.000540 0.000527 0.002631 0.000956 0.000426 0.000646 0.002323 0.001363
Nucleolus 0.000854 0.001394 0.000458 0.000365 0.000593 0.002175 0.000492 0.000247 0.000748 0.001485 0.000468 0.000324
Nucleus 0.125507 0.083053 0.640279* 0.166615* 0.123363 0.089589 0.401917* 0.145135* 0.124636 0.083811 0.570426* 0.159183*
Peroxisomes 0.003066 0.011841 0.000622 0.000801 0.003076 0.017208 0.000372 0.000759 0.003070 0.012463 0.000549 0.000786
Vacuole 0.060350 0.078983 0.077625 0.153192 0.045161 0.124182 0.207144* 0.205717* 0.054181 0.084224 0.115581 0.171367
Vacuole Periphery 0.000733 0.001400 0.000214 0.001606 0.000962 0.003103 0.000192 0.005482 0.000826 0.001597 0.000208 0.002947

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.65 -4.19 -0.91 1.36 4.25 -0.81 -4.18 -1.95 -1.77 -1.47 -2.33 -4.76 -2.22 -0.64 1.92
Bud Neck -2.53 9.66 9.98 7.21 0.79 -3.30 5.89 3.89 3.85 -4.01 -4.68 10.37 10.07 8.37 -0.33
Bud Site -5.82 -0.50 -5.20 -0.26 -4.47 -2.97 1.75 -4.01 -0.57 -4.49 -6.81 -0.34 -6.63 -0.18 -5.95
Cell Periphery -1.31 -6.67 3.42 3.70 8.22 -0.77 -3.87 2.70 1.27 5.15 -1.46 -7.66 4.41 3.82 9.59
Cytoplasm 8.25 37.26 18.82 6.95 -19.82 10.24 17.76 15.02 -2.17 -6.34 9.89 40.34 23.74 7.23 -19.75
Cytoplasmic Foci -8.01 41.74 39.41 31.26 -7.27 -3.76 31.38 37.35 15.20 2.39 -6.58 52.94 53.84 34.20 -2.32
Eisosomes 2.72 7.03 16.94 9.67 7.19 -1.64 -0.48 9.30 5.09 6.82 1.89 5.72 19.50 9.96 9.40
Endoplasmic Reticulum 0.25 -16.24 -12.26 -14.03 13.72 -0.17 -10.17 -10.54 -8.18 5.65 0.20 -17.70 -16.24 -16.86 14.30
Endosome -6.48 8.29 7.14 9.79 0.52 -5.42 3.31 7.33 6.46 4.26 -8.10 9.08 9.89 11.64 2.49
Golgi -2.99 6.74 1.40 3.46 -2.00 -1.76 5.65 4.33 2.22 -2.28 -3.30 8.67 3.11 4.34 -2.39
Lipid Particles 1.39 5.00 8.24 7.58 5.63 -1.30 3.07 9.09 2.49 6.46 0.61 6.32 12.05 6.51 8.32
Mitochondria -0.14 3.37 2.59 2.30 -2.35 -1.44 2.81 -0.42 1.36 -2.11 -1.31 4.23 1.66 2.24 -2.76
Mitotic Spindle -1.96 -1.30 -7.59 -5.90 -5.77 -1.18 -0.40 -4.42 -0.89 -4.22 -2.40 -1.40 -8.80 -5.91 -6.84
None 3.06 1.19 -0.49 -4.91 -2.45 3.32 -0.53 -2.36 -3.26 -2.09 2.82 0.51 -2.36 -4.64 -2.94
Nuclear Periphery -0.40 -21.11 -19.71 -21.40 2.11 -1.13 -13.99 -14.20 -5.81 2.18 -0.69 -25.46 -24.29 -23.98 3.13
Nuclear Periphery Foci -2.91 -9.21 -6.94 -4.69 5.44 0.06 -7.19 -6.49 -5.66 5.18 -2.59 -11.39 -8.79 -5.96 7.20
Nucleolus -0.94 3.23 4.55 1.68 2.60 -1.25 2.42 5.41 1.50 2.50 -1.35 3.81 6.06 2.03 3.58
Nucleus 8.47 -40.79 -18.87 -23.19 28.70 2.60 -13.38 -9.33 -7.50 9.31 9.05 -38.64 -20.81 -24.59 27.72
Peroxisomes -5.51 5.13 5.37 7.58 0.39 -3.01 7.79 7.02 3.60 -0.74 -6.35 7.78 7.95 8.38 0.18
Vacuole -5.72 -8.70 -26.71 -21.53 -11.87 -6.15 -13.41 -28.29 -13.06 -3.11 -9.07 -14.93 -38.24 -28.46 -11.17
Vacuole Periphery -1.66 5.84 1.13 2.05 -2.61 -3.41 3.18 -0.75 1.82 -1.99 -2.09 5.51 -0.20 1.66 -2.78
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Constituent of 66S pre-ribosomal particles; forms a complex with Nop7p and Ytm1p that is required for maturation of the large ribosomal subunit; required for maturation of the 25S and 5.8S ribosomal RNAs; homologous to mammalian Bop1
Localization
Cell Percentages cytoplasm (75%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Erb1

Erb1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erb1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available