Standard name
Human Ortholog
Description Subunit of a complex with Ctf8p; shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.07 0 0.33 0.23 0.29 0.19 0.18 0.15 0.1 0.12 0.12 0.12 0.11 0.2 0.3 0.14 0.1 0.26 0 0 0.12 0.05 0.11 0.15
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.33 0.41 0.05 0.16 0.09 0.37 0.44 0.23 0.66 0.65 0.69 0.54 0.24 0.06 0.08 0 0.07 0.17 0 0 0 0 0 0.05
Nucleus 0.68 0.78 0.55 0.66 0.62 0.6 0.57 0.71 0.59 0.58 0.57 0.55 0.65 0.61 0.45 0.66 0.74 0.46 0.67 0.63 0.46 0.54 0.34 0.26
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.05 0.06 0.05 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0
Vac/Vac Membrane 0.12 0.12 0 0 0 0 0 0 0 0 0 0 0.11 0.11 0.19 0.18 0.21 0.23 0.2 0.19 0.24 0.31 0.39 0.4
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3
Bud 0 1 0 1 0 1 2 2 5 7 9 9 0 0 2 0 0 0 0 2 2 5 13 11
Bud Neck 0 0 8 1 6 1 4 11 1 7 2 3 0 0 0 0 0 0 0 0 0 1 4 8
Bud Site 0 0 0 0 0 1 13 2 5 9 9 22 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9 1 62 37 71 55 75 59 31 40 47 51 31 91 126 8 4 9 3 2 31 10 48 56
Endoplasmic Reticulum 1 0 3 0 0 1 0 0 0 0 1 0 0 2 1 1 1 3 0 0 0 1 0 3
Endosome 0 0 0 0 1 2 2 0 0 0 0 0 5 24 15 1 0 1 0 2 3 0 5 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 0 0 6 1
Mitochondria 41 24 9 25 21 108 185 90 209 224 271 233 68 27 32 1 3 6 0 0 8 5 17 18
Nucleus 86 46 103 107 151 173 236 282 187 200 225 238 188 279 193 37 31 16 91 52 118 107 150 98
Nuclear Periphery 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1 1 0 0 0 0 0 0 1 1
Nucleolus 2 0 0 0 0 0 3 0 1 3 1 2 12 21 18 1 1 0 4 1 6 0 2 2
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
SpindlePole 1 0 9 9 13 4 20 21 8 8 6 16 2 6 3 0 0 0 4 3 16 1 6 11
Vac/Vac Membrane 15 7 6 2 5 9 8 13 10 3 12 17 33 51 79 10 9 8 27 16 61 62 169 150
Unique Cell Count 126 59 186 161 245 289 416 399 315 347 392 435 289 459 426 56 42 35 137 84 258 199 435 375
Labelled Cell Count 155 79 201 182 268 355 548 482 457 502 583 592 339 501 471 60 49 43 137 84 258 199 435 375


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 3.8 4.8 4.4 4.8 3.8 4.0 4.4 3.5 3.3 3.4 3.8 4.4 4.5 4.4 6.9 6.3 7.2 4.0 4.0 4.4
Std Deviation (1e-4) 0.5 0.5 1.0 1.3 1.1 0.9 1.1 1.1 0.9 1.0 1.0 0.8 0.9 0.9 1.2 1.9 1.0 2.1 1.0 1.3 1.5
Intensity Change (Log2) – – – -0.12 -0.0 -0.32 -0.27 -0.12 -0.44 -0.52 -0.51 -0.34 -0.13 -0.11 -0.11 0.52 0.4 0.59 -0.25 -0.25 -0.12

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.6376 -0.586 -0.5708 0.48 -0.1914 -0.4946 -0.4827 -0.0179 0.0883 -0.4881 -0.0102 -0.255 -0.6268 -0.1273 0.0032 -0.1746 -0.1521 -0.3707
Actin 0.0861 0.0007 0.0044 0.1042 0.0068 0.0054 0.0055 0.0001 0.0089 0 0.0012 0.0003 0.0386 0.0001 0.0193 0.0005 0.002 0.0018
Bud 0.0022 0.0002 0.0002 0.0015 0.0003 0.0002 0.0011 0.0001 0.0003 0 0.0003 0.0001 0.0005 0.0001 0.0005 0 0.0002 0.0001
Bud Neck 0.003 0.001 0.0006 0.0038 0.0003 0.0028 0.0102 0.0004 0.001 0.0002 0.001 0.0018 0.0022 0.0003 0.0061 0.0003 0.0014 0.0015
Bud Periphery 0.0046 0.0003 0.0005 0.0016 0.001 0.0005 0.0024 0.0002 0.0006 0 0.0005 0.0002 0.0009 0.0001 0.0007 0 0.0002 0.0001
Bud Site 0.006 0.0101 0.0038 0.0153 0.0005 0.0015 0.0094 0.0004 0.0018 0 0.0005 0.0002 0.0019 0.0004 0.0041 0.0002 0.0008 0.0001
Cell Periphery 0.0005 0.0003 0.0001 0.0004 0.0002 0.0001 0.0008 0 0.0003 0 0.0001 0 0.0002 0 0.0001 0 0.0001 0
Cytoplasm 0.0285 0.011 0.0055 0.0066 0.0006 0.016 0.0199 0.0174 0.0071 0.001 0.0132 0.0088 0.0132 0.0063 0.0077 0.0015 0.0051 0.0041
Cytoplasmic Foci 0.0218 0.0006 0.0033 0.0671 0.0086 0.0044 0.0223 0.0002 0.0112 0 0.004 0.0012 0.0052 0.0022 0.0156 0.01 0.007 0.0037
Eisosomes 0.0012 0.0001 0.0001 0.0005 0.0003 0.0001 0.0001 0 0.0001 0 0 0 0.0005 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0103 0.0018 0.0076 0.0046 0.0012 0.0008 0.0035 0.0022 0.0014 0 0.0029 0.0008 0.0029 0.0003 0.0005 0.0001 0.0005 0.0002
Endosome 0.0285 0.002 0.0033 0.0903 0.0471 0.0105 0.0531 0.0006 0.023 0.0001 0.0248 0.0032 0.0151 0.0003 0.0104 0.0137 0.0319 0.0017
Golgi 0.0138 0.0005 0.0013 0.0286 0.0197 0.0103 0.0099 0 0.0078 0 0.006 0.0003 0.0095 0 0.0079 0.0086 0.0203 0.001
Lipid Particles 0.0179 0.0014 0.0018 0.0524 0.1112 0.0056 0.0313 0 0.0067 0 0.0325 0.0009 0.0118 0.0003 0.0072 0.0168 0.0103 0.0055
Mitochondria 0.0315 0.005 0.0038 0.0108 0.1855 0.002 0.0161 0.0004 0.0031 0.0003 0.0294 0.0004 0.0156 0.0002 0.0032 0.001 0.0887 0.0003
None 0.032 0.0264 0.0198 0.0025 0.0005 0.016 0.0249 0.0219 0.0091 0.0002 0.0444 0.0188 0.0347 0.0995 0.0297 0.0526 0.0008 0.002
Nuclear Periphery 0.036 0.0224 0.0176 0.0076 0.0104 0.0086 0.0205 0.0177 0.021 0.0036 0.023 0.0117 0.0162 0.012 0.0086 0.0026 0.004 0.0038
Nucleolus 0.0097 0.0162 0.0306 0.0038 0.0012 0.0166 0.0171 0.0159 0.0327 0.01 0.0231 0.0276 0.0121 0.0145 0.0157 0.0021 0.0073 0.0195
Nucleus 0.592 0.8769 0.8562 0.5538 0.5922 0.8581 0.6959 0.9109 0.8377 0.977 0.7639 0.9002 0.7891 0.8499 0.843 0.8837 0.7848 0.9198
Peroxisomes 0.0279 0.0003 0.0051 0.0305 0.0055 0.0019 0.0101 0 0.0078 0 0.0103 0.0005 0.0033 0 0.0071 0.0033 0.0023 0.0073
Punctate Nuclear 0.038 0.0201 0.0321 0.0074 0.0027 0.0373 0.0319 0.0103 0.0126 0.0073 0.0132 0.0223 0.0228 0.0131 0.0108 0.0024 0.0297 0.027
Vacuole 0.0054 0.0019 0.0011 0.0047 0.0018 0.0009 0.0116 0.001 0.0048 0.0001 0.0033 0.0004 0.0021 0.0003 0.0012 0.0003 0.0016 0.0004
Vacuole Periphery 0.0027 0.0006 0.001 0.0019 0.0023 0.0003 0.0025 0.0003 0.001 0 0.0024 0.0002 0.0016 0.0001 0.0004 0.0002 0.0008 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.2284 11.521 7.5627 16.1879 29.8848 24.7707 11.4249 11.0373 11.7596 28.5406
Translational Efficiency 0.7798 0.7048 0.5393 0.5021 0.5122 0.8714 0.5571 0.4497 0.6044 0.5452

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1400 1473 78 1289 1674 1320 484 1999 3074 2793 562 3288

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 613.14 746.27 994.80 838.62 679.88 743.52 909.88 845.20 649.48 744.97 921.67 842.62
Standard Deviation 80.31 100.75 135.86 110.49 84.49 96.91 96.45 115.74 89.05 98.96 106.93 113.76
Intensity Change Log 2 — 0.283481 0.698190 0.451801 — 0.129091 0.420396 0.314013 — 0.204364 0.558804 0.380993

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000021 0.000199 0.001809 0.001535 0.000219 0.000269 0.000494 0.000362 0.000129 0.000232 0.000676 0.000822
Bud Neck 0.001669 0.006195 0.004015 0.018366 0.002339 0.009818 0.005030 0.011719 0.002034 0.007907 0.004889 0.014325
Bud Site 0.000487 0.002236 0.001645 0.024419 0.001337 0.003191 0.001607 0.008144 0.000950 0.002687 0.001612 0.014524
Cell Periphery 0.000174 0.000131 0.000153 0.000199 0.000127 0.000182 0.000080 0.000120 0.000149 0.000155 0.000090 0.000151
Cytoplasm 0.321437 0.144401 0.015389 0.100645 0.174867 0.163194 0.030804 0.057976 0.241620 0.153283 0.028665 0.074704
Cytoplasmic Foci 0.045585 0.026161 0.001206 0.004595 0.024805 0.046457 0.001209 0.001293 0.034269 0.035753 0.001208 0.002587
Eisosomes 0.000056 0.000036 0.000066 0.000035 0.000035 0.000061 0.000039 0.000019 0.000044 0.000048 0.000043 0.000025
Endoplasmic Reticulum 0.000375 0.001982 0.016256 0.007297 0.001377 0.002035 0.006524 0.004441 0.000921 0.002007 0.007874 0.005560
Endosome 0.001230 0.002376 0.000754 0.005609 0.001590 0.002905 0.000660 0.001564 0.001426 0.002626 0.000673 0.003150
Golgi 0.000427 0.000795 0.000113 0.002455 0.000291 0.001250 0.000055 0.000558 0.000353 0.001010 0.000063 0.001302
Lipid Particles 0.002909 0.003551 0.001028 0.000849 0.003154 0.007580 0.000720 0.000367 0.003043 0.005455 0.000763 0.000556
Mitochondria 0.000973 0.002715 0.001074 0.008027 0.002949 0.007609 0.000678 0.003419 0.002049 0.005028 0.000733 0.005226
Mitotic Spindle 0.000264 0.002927 0.002436 0.038242 0.003062 0.004822 0.000700 0.013297 0.001788 0.003823 0.000941 0.023076
None 0.030907 0.011637 0.001067 0.010802 0.014217 0.008284 0.008155 0.007220 0.021818 0.010053 0.007171 0.008624
Nuclear Periphery 0.000518 0.001352 0.000998 0.003826 0.001047 0.002044 0.001114 0.002234 0.000806 0.001679 0.001098 0.002858
Nuclear Periphery Foci 0.000380 0.001185 0.000447 0.001498 0.001074 0.000988 0.000330 0.000814 0.000758 0.001092 0.000346 0.001082
Nucleolus 0.005005 0.010040 0.002289 0.001877 0.007460 0.007655 0.002162 0.001227 0.006342 0.008913 0.002180 0.001482
Nucleus 0.582154 0.772613 0.936028 0.727832 0.753734 0.716217 0.929357 0.872642 0.675591 0.745960 0.930283 0.815872
Peroxisomes 0.000957 0.003386 0.000384 0.000979 0.001437 0.006096 0.000230 0.000141 0.001218 0.004667 0.000251 0.000469
Vacuole 0.004236 0.005506 0.012648 0.035396 0.004471 0.008396 0.009923 0.010938 0.004364 0.006872 0.010301 0.020526
Vacuole Periphery 0.000238 0.000575 0.000195 0.005518 0.000407 0.000945 0.000129 0.001507 0.000330 0.000750 0.000139 0.003079

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.80 -7.55 -6.30 -5.15 3.49 -0.56 -4.54 -2.91 -4.47 3.31 -2.24 -8.91 -7.15 -6.63 2.14
Bud Neck -6.07 -3.58 -12.55 -7.38 -5.23 -6.50 -4.06 -12.06 -3.71 -6.15 -8.78 -5.14 -17.27 -7.78 -8.03
Bud Site -2.81 -4.08 -7.25 -5.86 -5.63 -2.44 -1.38 -4.54 -2.17 -3.34 -3.53 -2.66 -8.52 -5.89 -6.33
Cell Periphery 3.20 -0.71 1.44 -1.56 1.36 -2.74 3.57 3.00 4.35 -0.49 -0.52 4.66 3.55 2.98 -1.35
Cytoplasm 20.41 30.41 29.08 9.14 -8.37 1.54 24.40 21.49 18.94 -6.18 15.26 40.61 35.52 20.59 -10.73
Cytoplasmic Foci 6.20 17.44 17.03 11.68 -2.15 -5.90 13.67 13.86 15.62 0.93 -0.30 22.20 21.92 19.59 -1.41
Eisosomes 4.15 -2.31 0.44 -4.83 2.59 -4.79 -2.63 3.71 7.36 4.90 -1.49 -2.07 3.45 4.66 3.97
Endoplasmic Reticulum -9.55 -8.83 -22.05 -17.67 3.93 -2.71 -11.17 -19.69 -12.76 3.95 -7.72 -14.12 -29.43 -21.89 3.57
Endosome -1.94 1.04 -3.45 -0.65 -4.37 -2.40 2.99 1.88 3.84 -1.05 -2.90 3.04 -1.12 2.10 -4.12
Golgi -0.93 1.28 -1.29 -0.22 -2.43 -2.89 5.09 0.48 2.95 -2.14 -2.60 2.99 -0.89 1.94 -3.31
Lipid Particles -1.66 6.12 7.29 6.68 0.55 -5.16 7.58 9.19 9.16 4.51 -5.17 10.28 11.92 11.43 2.62
Mitochondria -4.01 -1.62 -3.62 -1.47 -3.01 -3.69 2.44 0.22 4.58 -3.99 -4.43 2.29 -1.93 2.77 -5.32
Mitotic Spindle -3.47 -1.22 -8.85 -7.62 -4.03 -1.39 1.64 -5.29 -3.93 -6.92 -2.68 -0.07 -10.22 -8.44 -9.79
None 6.79 11.30 8.38 3.35 -7.25 4.58 4.53 6.37 1.99 -0.16 7.93 8.90 10.47 4.24 -1.03
Nuclear Periphery -6.02 -4.03 -10.06 -8.01 -7.59 -3.71 -4.71 -13.13 -4.43 -9.37 -6.14 -7.23 -15.60 -9.65 -11.36
Nuclear Periphery Foci -2.93 -0.99 -5.50 0.76 -4.89 1.58 3.07 1.31 -0.01 -1.23 -1.34 2.28 -0.62 0.80 -2.63
Nucleolus -3.10 3.23 3.52 7.58 0.53 0.98 5.99 5.93 6.03 -0.02 -1.59 6.62 6.79 9.58 0.16
Nucleus -17.30 -23.21 -14.41 1.95 11.93 3.45 -19.33 -14.74 -17.01 7.04 -9.14 -32.58 -21.33 -11.59 14.52
Peroxisomes -3.82 2.43 2.31 4.94 0.01 -4.81 3.46 3.80 6.81 2.17 -5.98 4.42 4.54 8.50 0.37
Vacuole -3.35 -4.41 -15.28 -14.71 -9.55 -4.24 -5.49 -9.17 -6.58 -0.38 -5.23 -6.36 -17.49 -15.82 -6.67
Vacuole Periphery -1.45 -0.02 -2.96 -2.27 -2.98 -2.08 2.81 -1.06 0.59 -2.05 -2.42 2.59 -3.03 -1.44 -3.70
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of a complex with Ctf8p; shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint
Localization
Cell Percentages nucleus (52%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Ctf18

Ctf18


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ctf18-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available