Standard name
Human Ortholog
Description Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.1 0.08 – – – 0 0 0 0 0 0
Cytoplasm 0.38 0.36 0.28 0.34 0.39 0.31 0.23 0.16 0.18 0.13 0.14 0.12 0.32 0.2 0.25 – – – 0.09 0.1 0.06 0.08 0.07 0.06
Endoplasmic Reticulum 0.75 0.7 0.69 0.54 0.42 0.41 0.22 0.19 0.2 0.14 0.16 0.18 0.65 0.75 0.71 – – – 0.81 0.79 0.84 0.75 0.74 0.73
Endosome 0 0 0 0 0 0 0.05 0.05 0 0.06 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0.09 0.16 0.17 0.28 0.36 0.42 0.42 0.4 0.6 0.63 0 0 0 – – – 0 0 0 0.05 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0.12 0.15 0.31 0.31 0.28 0.36 0.2 0.15 0.07 0 0 – – – 0 0 0 0.05 0.07 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 6 8 8 9 13 9 7 19 13 14 13 18 9 13 – – – 0 1 6 6 6 9
Bud 0 0 3 2 5 17 30 29 22 20 25 18 2 0 0 – – – 0 0 0 2 4 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 1 2 3 3 3 6
Bud Site 0 0 0 0 0 0 0 3 0 4 2 3 0 0 0 – – – – – – – – –
Cell Periphery 0 6 5 10 16 9 13 4 8 9 5 5 21 26 34 – – – 0 0 2 2 4 7
Cytoplasm 6 52 76 83 152 133 168 93 123 95 86 84 126 52 104 – – – 3 17 19 27 24 21
Endoplasmic Reticulum 12 100 185 130 161 175 160 114 134 99 99 129 257 196 293 – – – 30 136 282 255 256 253
Endosome 0 0 0 7 7 4 34 32 26 45 10 14 8 3 6 – – – 0 2 0 1 3 2
Golgi 0 1 1 0 0 0 0 1 1 5 3 5 1 1 6 – – – 0 0 0 2 4 5
Mitochondria 0 0 23 39 67 118 265 248 286 291 370 458 2 0 0 – – – 0 0 9 16 11 9
Nucleus 0 0 0 1 0 2 8 4 5 9 9 13 0 1 0 – – – 0 1 0 0 0 0
Nuclear Periphery 0 0 1 1 1 3 7 9 12 10 19 13 0 0 0 – – – 0 0 1 0 0 2
Nucleolus 0 0 0 0 1 0 7 11 6 13 8 22 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 1 0 0 0 1 0 6 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 6 3 11 45 62 225 188 187 262 121 109 29 8 12 – – – 0 6 5 18 23 23
Unique Cell Count 16 143 270 241 387 424 736 597 674 721 617 730 397 263 412 38 173 335 340 348 347
Labelled Cell Count 18 171 305 293 464 536 926 744 829 882 771 886 464 296 468 38 173 335 340 348 347


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.9 11.6 7.3 7.4 7.3 6.9 6.7 7.1 7.4 7.3 7.1 7.3 10.1 10.8 11.7 – – – 10.8 10.9 11.4
Std Deviation (1e-4) 1.9 1.8 1.1 1.3 1.3 1.1 1.3 1.5 1.6 1.6 1.8 1.8 1.3 1.5 1.7 – – – 2.2 2.0 2.0
Intensity Change (Log2) – – – 0.02 -0.0 -0.09 -0.12 -0.05 0.02 0.0 -0.03 -0.01 0.48 0.56 0.68 – – – 0.57 0.57 0.65

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.2 -0.5 0.1 0 0 -0.1 -1.1 -0.6 -1.2 1.0 0.3 0.1 – – –
Bud 0 0 2.2 2.3 2.7 1.9 1.5 2.3 1.3 0 0 0 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 1.5 1.6 0.2 0 0 0 0 0 0 2.3 4.0 3.5 – – –
Cytoplasm 1.5 2.9 0.9 -1.7 -4.3 -3.4 -5.6 -5.0 -6.4 1.0 -2.3 -0.8 – – –
Endoplasmic Reticulum -3.4 -6.8 -7.0 -13.9 -14.2 -14.3 -17.0 -15.4 -15.4 -1.0 1.5 0.7 – – –
Endosome 0 0 0 3.6 3.9 3.3 4.2 0 0 0 0 0 – – –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Mitochondria 2.6 3.2 6.2 8.5 9.7 10.0 9.6 14.2 15.2 -5.3 -4.8 -6.0 – – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 0 0 2.5 0 0 0 0 – – –
Nucleolus 0 0 0 0 0 0 0 0 2.9 0 0 0 – – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Vacuole 2.4 5.1 6.0 9.9 10.0 9.2 11.2 7.3 6.2 3.7 1.6 1.6 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.511 5.506 4.5931 4.0009 3.9821 4.875 6.2524 7.3067 6.6958 6.3541 5.0964 6.6202 5.465 5.8242 5.1415 5.7688 4.8014 5.4203
Actin 0.0099 0.0013 0.0128 0.0033 0.0126 0.0039 0.0144 0.0103 0.0128 0.004 0.0045 0.0039 0.0112 0.0016 0.0068 0.0007 0.0023 0.0008
Bud 0.0073 0.0016 0.0056 0.0002 0.0008 0.0027 0.0002 0.0001 0.0011 0.0004 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0002 0
Bud Neck 0.0006 0.001 0.0019 0.0007 0.0013 0.0016 0.0006 0.0006 0.0051 0.0014 0.0012 0.0012 0.0003 0.0004 0.0006 0.0006 0.0006 0.0009
Bud Periphery 0.0022 0.001 0.0022 0.0006 0.0017 0.0007 0.0002 0.0002 0.0029 0.0012 0.0002 0.0002 0.0001 0.0001 0.0001 0.0004 0.0002 0.0001
Bud Site 0.0021 0.0195 0.0129 0.0005 0.0019 0.0006 0.0015 0.0022 0.0051 0.001 0.0002 0.0002 0.0003 0.0015 0.0005 0.0001 0.0004 0.0001
Cell Periphery 0.0016 0.0035 0.0031 0.0012 0.0034 0.0015 0.0019 0.0057 0.0054 0.003 0.0035 0.0025 0.0013 0.0016 0.0016 0.0022 0.0008 0.001
Cytoplasm 0.1168 0.2307 0.2057 0.1535 0.2038 0.2046 0.1053 0.1614 0.1248 0.1821 0.1908 0.1384 0.0474 0.09 0.093 0.0382 0.221 0.0888
Cytoplasmic Foci 0.0446 0.0127 0.0285 0.0148 0.0447 0.0171 0.0284 0.0139 0.0199 0.0194 0.0141 0.0145 0.0256 0.02 0.0218 0.0283 0.0274 0.014
Eisosomes 0.0001 0.0001 0.0001 0.0003 0.0003 0.0001 0.0003 0.0018 0.0004 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.5291 0.589 0.5244 0.6066 0.3839 0.6384 0.6253 0.6377 0.6419 0.654 0.6854 0.7085 0.6352 0.6683 0.6596 0.6783 0.5 0.6889
Endosome 0.1168 0.0492 0.0881 0.0718 0.1154 0.0544 0.0742 0.0414 0.0674 0.0518 0.0305 0.0423 0.0779 0.0479 0.059 0.0692 0.1218 0.0748
Golgi 0.033 0.008 0.0199 0.0106 0.0329 0.0103 0.0291 0.0099 0.0195 0.0225 0.0079 0.0159 0.016 0.0087 0.0153 0.0411 0.0131 0.0135
Lipid Particles 0.0518 0.0284 0.0418 0.0592 0.0487 0.0276 0.0746 0.0842 0.0542 0.0211 0.0404 0.041 0.1473 0.1348 0.1157 0.1139 0.0847 0.0918
Mitochondria 0.0078 0.0013 0.0119 0.0224 0.0412 0.0019 0.004 0.0014 0.0115 0.006 0.0016 0.0056 0.001 0.0004 0.0012 0.0016 0.0056 0.0016
None 0.013 0.0166 0.0113 0.0102 0.0622 0.0128 0.0073 0.0065 0.0013 0.0014 0.0082 0.0091 0.0084 0.0017 0.0011 0.001 0.0017 0.0011
Nuclear Periphery 0.0219 0.0135 0.0098 0.0258 0.0117 0.0086 0.0097 0.0082 0.007 0.009 0.005 0.0048 0.0142 0.0118 0.0123 0.0082 0.0072 0.0102
Nucleolus 0.0011 0.0005 0.0004 0.0003 0.001 0.0002 0.0003 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0001 0 0 0.0001 0
Nucleus 0.008 0.0055 0.0028 0.0016 0.0041 0.0026 0.0011 0.0011 0.0011 0.0014 0.0007 0.0006 0.0006 0.0014 0.0008 0.0005 0.0022 0.0013
Peroxisomes 0.011 0.0002 0.0023 0.0037 0.0052 0.0003 0.01 0.0004 0.0036 0.004 0.0005 0.0024 0.0013 0.0004 0.0005 0.0002 0.0003 0.0002
Punctate Nuclear 0.0077 0.002 0.0029 0.0007 0.0039 0.001 0.0031 0.0014 0.0006 0.0004 0.0004 0.0004 0.0012 0.0012 0.0007 0.0011 0.0012 0.0004
Vacuole 0.0112 0.0132 0.0095 0.0095 0.0158 0.0081 0.0074 0.0107 0.0127 0.0138 0.004 0.0073 0.0094 0.0078 0.0082 0.0125 0.0079 0.0091
Vacuole Periphery 0.0023 0.001 0.0018 0.0022 0.0035 0.001 0.001 0.0008 0.0018 0.0021 0.0006 0.0009 0.0011 0.0006 0.001 0.0015 0.0012 0.0014

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 36.1772 28.7468 27.3309 41.1241 26.0585 45.1965 33.1533 39.8481 41.2808 35.4753
Translational Efficiency 1.32 1.1784 1.4106 0.9889 1.2013 1.1711 1.286 0.9651 1.1855 1.1024

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2147 1447 1065 1438 1490 1478 321 1697 3637 2925 1386 3135

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 888.56 1005.65 1505.29 1413.21 786.93 1003.51 1351.35 1442.63 846.92 1004.57 1469.64 1429.14
Standard Deviation 120.41 186.29 235.10 218.63 128.48 151.75 176.85 245.58 133.49 169.72 232.23 234.06
Intensity Change Log 2 — 0.178587 0.760500 0.669435 — 0.350748 0.780094 0.874394 — 0.262009 0.769736 0.769332

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000527 0.003100 0.001914 0.007886 0.001137 0.001505 0.000636 0.006485 0.000777 0.002294 0.001618 0.007127
Bud Neck 0.002099 0.001712 0.003606 0.008877 0.003840 0.001823 0.002647 0.005680 0.002812 0.001768 0.003384 0.007146
Bud Site 0.007205 0.015788 0.011191 0.049175 0.014328 0.011533 0.008562 0.033007 0.010123 0.013638 0.010582 0.040423
Cell Periphery 0.001863 0.001698 0.009671 0.012328 0.001279 0.002313 0.006032 0.013801 0.001624 0.002009 0.008828 0.013125
Cytoplasm 0.107404 0.070401 0.071565 0.080657 0.127267 0.075812 0.042290 0.105450 0.115542 0.073135 0.064785 0.094077
Cytoplasmic Foci 0.036062 0.088529 0.006541 0.056977 0.129176 0.053217 0.006127 0.042604 0.074208 0.070686 0.006445 0.049196
Eisosomes 0.000510 0.000336 0.000093 0.000311 0.000424 0.000456 0.000115 0.000482 0.000475 0.000396 0.000098 0.000404
Endoplasmic Reticulum 0.701913 0.619781 0.775486 0.338899 0.444487 0.716815 0.828906 0.469196 0.596451 0.668812 0.787858 0.409430
Endosome 0.016508 0.045690 0.016590 0.082767 0.049737 0.024304 0.018676 0.043272 0.030121 0.034883 0.017073 0.061388
Golgi 0.030330 0.040518 0.004278 0.044173 0.056391 0.036442 0.004007 0.036250 0.041007 0.038459 0.004215 0.039884
Lipid Particles 0.043215 0.036976 0.025629 0.162675 0.061014 0.031895 0.023429 0.182158 0.050507 0.034409 0.025120 0.173222
Mitochondria 0.014550 0.012764 0.000331 0.002601 0.017300 0.010943 0.000178 0.002609 0.015676 0.011844 0.000296 0.002605
Mitotic Spindle 0.000485 0.000557 0.001213 0.019214 0.000713 0.001270 0.000518 0.003363 0.000579 0.000917 0.001052 0.010634
None 0.005149 0.002246 0.001589 0.001153 0.006874 0.001235 0.000133 0.001962 0.005856 0.001736 0.001252 0.001591
Nuclear Periphery 0.001002 0.001184 0.002526 0.001302 0.002846 0.000432 0.001204 0.000318 0.001757 0.000804 0.002220 0.000769
Nuclear Periphery Foci 0.003335 0.007647 0.025961 0.036130 0.011423 0.003998 0.025945 0.011674 0.006648 0.005803 0.025957 0.022892
Nucleolus 0.000210 0.000264 0.000022 0.000198 0.001233 0.000119 0.000012 0.000105 0.000629 0.000191 0.000020 0.000147
Nucleus 0.004230 0.002213 0.002020 0.002500 0.006804 0.002105 0.001768 0.001878 0.005284 0.002158 0.001961 0.002163
Peroxisomes 0.004159 0.003944 0.000181 0.001746 0.004076 0.004183 0.000266 0.002683 0.004125 0.004065 0.000200 0.002253
Vacuole 0.013288 0.030043 0.038356 0.082343 0.040888 0.012029 0.027611 0.032774 0.024595 0.020941 0.035867 0.055511
Vacuole Periphery 0.005956 0.014609 0.001238 0.008089 0.018763 0.007569 0.000939 0.004251 0.011203 0.011052 0.001169 0.006011

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.69 -2.83 -8.27 -4.64 -5.78 -1.56 2.33 -7.74 -7.19 -8.50 -5.15 -2.24 -11.51 -7.93 -8.15
Bud Neck 1.21 -2.91 -9.30 -10.06 -5.48 2.64 1.14 -2.39 -6.15 -3.49 2.76 -1.58 -8.59 -11.53 -5.50
Bud Site -4.89 -2.36 -13.60 -10.65 -11.59 1.47 1.68 -7.87 -8.70 -6.68 -2.75 -0.53 -15.75 -13.63 -13.44
Cell Periphery 0.65 -6.78 -7.65 -7.82 -1.35 -4.16 -2.45 -12.76 -11.43 -3.59 -2.04 -7.30 -13.99 -13.49 -3.27
Cytoplasm 8.15 6.09 4.74 -2.51 -1.63 9.84 12.04 3.48 -5.65 -8.89 12.43 10.83 5.04 -6.03 -6.13
Cytoplasmic Foci -13.37 14.84 -6.99 7.32 -18.64 15.36 29.15 18.98 3.09 -15.70 1.14 30.03 9.60 7.78 -23.52
Eisosomes 2.47 6.73 3.19 0.72 -8.60 -0.47 5.63 -0.97 -0.42 -9.31 1.52 8.83 1.63 -0.10 -13.33
Endoplasmic Reticulum 7.21 -5.96 32.75 22.41 34.31 -21.67 -21.81 -1.67 20.74 20.98 -8.39 -19.05 22.04 29.55 37.66
Endosome -13.27 -0.29 -21.85 -10.38 -21.40 10.39 9.22 2.38 -8.55 -7.67 -2.99 9.02 -15.95 -12.70 -22.63
Golgi -3.88 16.19 -4.52 -0.84 -16.18 5.87 19.34 6.17 0.13 -14.35 1.21 25.23 0.78 -0.40 -21.97
Lipid Particles 2.09 5.15 -18.88 -19.79 -20.99 8.40 7.42 -18.25 -23.74 -21.72 7.19 8.98 -26.80 -30.84 -30.85
Mitochondria 1.05 12.90 9.90 7.38 -4.34 3.74 14.38 11.71 6.54 -6.02 3.19 18.90 15.01 9.87 -7.10
Mitotic Spindle -0.31 -1.51 -8.55 -8.54 -8.05 -0.84 0.21 -2.96 -1.96 -2.84 -0.95 -1.36 -8.94 -8.40 -8.08
None 3.17 3.51 4.72 1.90 0.60 5.61 6.85 4.39 -1.20 -3.27 6.21 5.83 6.15 0.39 -0.54
Nuclear Periphery -0.36 -2.43 -1.43 -0.31 1.87 3.76 2.26 3.93 1.11 2.69 2.59 -0.88 3.30 0.03 2.96
Nuclear Periphery Foci -4.36 -11.70 -13.93 -11.58 -3.48 5.48 -3.89 -0.37 -6.52 3.78 1.09 -11.03 -12.44 -12.98 1.39
Nucleolus -0.62 8.10 0.10 0.56 -2.49 3.08 3.36 3.10 0.31 -2.25 2.85 4.01 3.12 0.71 -3.20
Nucleus 5.17 5.31 3.70 -1.52 -1.66 6.48 4.13 6.73 0.48 -0.02 8.37 7.15 7.96 -0.74 -0.64
Peroxisomes 0.39 13.99 7.37 4.32 -8.15 -0.25 12.15 3.82 4.07 -10.86 0.17 18.52 7.59 5.77 -13.70
Vacuole -7.00 -9.34 -18.14 -12.57 -9.89 11.55 2.64 2.32 -9.52 -1.12 2.21 -4.98 -13.63 -14.93 -6.66
Vacuole Periphery -8.11 10.45 -2.17 5.21 -8.04 8.84 15.02 12.07 4.43 -5.49 0.18 18.14 7.56 6.99 -10.06
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages ER (91%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Yim1

Yim1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yim1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available