Standard name
Human Ortholog
Description Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.06 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.15 0.15 0.15 0 0 0 0 0 0
Cytoplasm 0 0.1 0.06 0.09 0.1 0 0 0.05 0 0 0 0 0.18 0.22 0.23 0.23 0.21 0.22 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0.06 0.06 0.05 0 0.06 0 0 0 0 0 0
Endosome 0.05 0 0.12 0.16 0 0.13 0.06 0.06 0 0.05 0 0 0.16 0.12 0.25 0.06 0.08 0 0.1 0.07 0.09 0.07 0.07 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.11 0 0.06 0.18 0.28 0 0 0 0 0.05 0
Mitochondria 0.84 0.75 0.5 0.73 0.73 0.72 0.67 0.69 0.95 0.87 0.92 0.93 0.44 0.22 0.31 0.14 0.12 0.08 0.72 0.72 0.71 0.74 0.68 0.7
Nucleus 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.09 0.07 0 0 0 0 0 0 0 0 0 0.05 0.18 0.18 0.15 0.06 0 0 0.09 0 0.06 0
SpindlePole 0 0 0.16 0 0.08 0.07 0.13 0.11 0 0.06 0 0.05 0 0.05 0 0.07 0.06 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0.12 0.19 0.12 0.11 0.05 0.14 0.13 0.15 0 0.06 0 0 0.14 0.16 0.12 0.16 0.19 0.19 0 0.06 0 0.05 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 10 4 3 2 5 0 1 0 1 1 0 0 3 8 1 0 2 2 16 14 2 3 11 9
Bud 10 7 4 4 8 7 5 8 31 17 17 19 1 2 2 12 6 4 1 1 0 2 2 2
Bud Neck 0 0 1 0 4 1 3 2 2 2 1 1 0 2 0 0 1 0 6 5 1 1 2 3
Bud Site 2 1 0 1 0 0 4 2 10 2 0 4 0 0 0 1 1 1 – – – – – –
Cell Periphery 16 24 6 7 1 5 3 4 5 2 4 4 7 1 3 26 44 38 1 2 0 0 0 1
Cytoplasm 15 42 12 18 23 11 14 14 17 16 12 14 25 19 47 40 64 55 1 4 1 2 4 3
Endoplasmic Reticulum 22 12 7 2 12 5 9 4 8 2 2 4 4 5 12 9 11 14 2 2 1 1 2 5
Endosome 28 10 23 32 3 35 22 17 2 26 7 1 22 10 51 11 24 8 74 36 26 19 27 24
Golgi 8 11 7 5 0 0 0 1 0 0 1 1 7 9 1 11 56 70 29 22 8 8 18 12
Mitochondria 508 311 94 149 163 195 264 206 589 472 441 474 60 19 63 25 35 21 545 365 215 204 253 257
Nucleus 7 2 3 3 7 10 21 10 10 10 9 11 1 3 0 8 6 9 1 2 0 1 1 1
Nuclear Periphery 6 1 1 1 0 1 7 7 13 14 9 7 0 0 1 1 3 0 7 2 1 1 1 3
Nucleolus 4 1 0 0 0 2 1 2 4 6 6 7 0 0 0 0 1 0 2 0 1 1 0 0
Peroxisomes 9 9 16 15 0 3 0 3 2 10 4 1 5 4 37 31 44 14 25 8 26 12 23 12
SpindlePole 23 7 31 8 18 19 51 32 24 35 20 27 6 4 9 12 17 21 7 3 3 1 4 3
Vac/Vac Membrane 73 77 22 23 12 39 50 45 23 32 18 22 19 14 24 29 58 49 19 30 8 12 13 18
Unique Cell Count 606 413 188 205 222 272 393 298 620 540 477 509 137 85 206 177 303 254 755 509 302 277 375 368
Labelled Cell Count 741 519 230 270 256 333 455 357 741 647 551 597 160 100 251 216 373 306 755 509 302 277 375 368


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 4.9 5.7 5.6 4.7 5.0 5.0 5.2 4.0 4.6 4.3 4.4 6.0 6.0 5.7 6.2 7.6 8.2 6.1 6.6 6.8
Std Deviation (1e-4) 0.7 0.8 0.8 1.2 1.3 0.7 0.9 1.0 0.7 0.8 0.7 0.6 1.0 0.9 1.3 1.6 2.1 2.3 1.1 1.4 1.5
Intensity Change (Log2) – – – -0.03 -0.29 -0.18 -0.17 -0.13 -0.52 -0.3 -0.4 -0.37 0.07 0.07 0.01 0.12 0.42 0.53 0.09 0.2 0.25

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 2.2 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.1 0 0 0 0 0 0 0 0 0.9 0 0 3.9 4.0 4.1
Cytoplasm 0.9 1.4 -1.1 -1.5 -0.8 -2.4 -2.1 -2.4 -2.2 3.3 3.9 4.6 4.4 4.4 4.4
Endoplasmic Reticulum 0 0 0 -1.0 0 0 0 0 0 0 0 1.0 0.6 -0.1 0.9
Endosome 1.0 0 0.2 -2.8 -2.6 0 0 0 0 1.0 -0.1 3.2 -2.0 -1.6 -3.7
Golgi -0.7 0 0 0 0 0 0 0 0 0.6 0 0 1.1 4.8 6.5
Mitochondria 4.6 0 4.7 4.0 4.2 0 0 0 0 -1.1 -4.3 -3.9 -7.3 -9.4 -9.9
Nucleus 0 0 1.3 2.1 1.2 0 0 0 0 0 0 0 1.6 0 1.2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes -0.4 0 -3.9 -5.9 -4.2 0 0 0 0 -1.8 -1.1 2.7 2.6 2.0 -1.2
SpindlePole -4.2 0 -3.2 -1.1 -1.8 0 0 0 0 -3.4 -2.7 -4.0 -2.9 -3.9 -2.7
Vacuole -0.2 -2.3 0.8 0.3 1.1 -4.2 -2.6 -3.9 -3.6 0.6 1.1 0 1.3 2.2 2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3329 1.4884 1.3286 1.2828 1.2475 1.5676 6.7998 6.9783 6.8611 6.9442 7.351 7.4163 3.8654 3.7187 4.0806 4.2566 3.7998 4.2022
Actin 0.0322 0.014 0.008 0.0283 0.0227 0.0101 0.0318 0.0167 0.021 0.0205 0.0418 0.0221 0.0133 0.007 0.0145 0.0046 0.0035 0.0067
Bud 0.0499 0.0581 0.0815 0.0806 0.0301 0.0513 0.0021 0.0029 0.0023 0.0018 0.0014 0.0009 0.0006 0.0038 0.0016 0.0012 0.0008 0.0015
Bud Neck 0.0062 0.0014 0.0019 0.0071 0.002 0.0058 0.003 0.0009 0.0033 0.0014 0.001 0.0022 0.0011 0.001 0.0015 0.0008 0.0005 0.0036
Bud Periphery 0.0191 0.0169 0.0241 0.0406 0.0074 0.0233 0.0055 0.0048 0.0063 0.006 0.0068 0.0022 0.0014 0.0033 0.0043 0.0021 0.0036 0.0037
Bud Site 0.0328 0.091 0.051 0.0422 0.0129 0.0066 0.0053 0.0246 0.0089 0.0033 0.002 0.0013 0.0029 0.0182 0.0058 0.0023 0.0012 0.003
Cell Periphery 0.0026 0.0021 0.0029 0.0031 0.0009 0.0026 0.0014 0.0007 0.001 0.001 0.0046 0.0006 0.0016 0.001 0.0018 0.0004 0.0003 0.0012
Cytoplasm 0.0292 0.0259 0.0419 0.0238 0.0571 0.1022 0.0093 0.0119 0.0079 0.0237 0.0052 0.0047 0.0041 0.0098 0.0138 0.0055 0.0044 0.009
Cytoplasmic Foci 0.0807 0.0764 0.0358 0.0509 0.0734 0.0861 0.0476 0.0629 0.0387 0.0456 0.0273 0.0474 0.0463 0.0457 0.0477 0.0357 0.0392 0.052
Eisosomes 0.0008 0.0005 0.0005 0.0007 0.0001 0.0002 0.0012 0.0004 0.0005 0.0016 0.0022 0.0004 0.0006 0.0003 0.0008 0.0006 0.0003 0.0005
Endoplasmic Reticulum 0.0028 0.0014 0.0011 0.0014 0.0008 0.0016 0.0026 0.003 0.0014 0.0053 0.0034 0.0011 0.0018 0.0017 0.0015 0.0004 0.0008 0.0016
Endosome 0.0937 0.1003 0.0537 0.0736 0.1312 0.0482 0.1236 0.1186 0.0698 0.1044 0.118 0.0953 0.1296 0.1334 0.0858 0.0523 0.0549 0.0936
Golgi 0.0659 0.0771 0.0327 0.034 0.0698 0.0463 0.1037 0.1076 0.075 0.1115 0.1605 0.0991 0.0991 0.1139 0.0823 0.0487 0.0704 0.1092
Lipid Particles 0.0332 0.0095 0.0062 0.0324 0.0057 0.0253 0.0328 0.0086 0.0146 0.0212 0.0066 0.0119 0.0345 0.0116 0.0133 0.0098 0.014 0.0195
Mitochondria 0.4289 0.4279 0.5492 0.4489 0.4741 0.4453 0.5461 0.5603 0.6832 0.5656 0.5638 0.6503 0.5987 0.5937 0.6562 0.748 0.7081 0.6207
None 0.0391 0.0074 0.0212 0.0411 0.0143 0.0385 0.0128 0.0155 0.0139 0.0358 0.0039 0.0056 0.0116 0.0036 0.0115 0.0205 0.0032 0.0116
Nuclear Periphery 0.0046 0.001 0.0018 0.0022 0.0015 0.0042 0.003 0.0021 0.0017 0.0016 0.0007 0.0009 0.0006 0.0003 0.0003 0.0001 0.0002 0.0007
Nucleolus 0.0053 0.0026 0.0052 0.007 0.0038 0.0063 0.0005 0.0005 0.0008 0.0007 0.0002 0.0002 0.0003 0.0004 0.0005 0.0001 0.0003 0.0006
Nucleus 0.0057 0.006 0.0216 0.0212 0.0317 0.0237 0.0014 0.0006 0.0008 0.0009 0.0003 0.0003 0.0003 0.0005 0.0005 0.0002 0.0002 0.0007
Peroxisomes 0.0508 0.0611 0.0474 0.0363 0.03 0.0486 0.0507 0.047 0.0396 0.0361 0.0427 0.0464 0.0425 0.0385 0.0472 0.0628 0.0888 0.0498
Punctate Nuclear 0.0059 0.0089 0.0039 0.0084 0.0187 0.0137 0.0008 0.0009 0.0011 0.0012 0.0002 0.0003 0.0003 0.0002 0.0003 0.0001 0.0003 0.0007
Vacuole 0.0076 0.0071 0.0063 0.0114 0.0081 0.0069 0.0097 0.0057 0.005 0.0064 0.004 0.0037 0.0055 0.008 0.0058 0.0017 0.0025 0.0059
Vacuole Periphery 0.0032 0.0033 0.0021 0.005 0.0036 0.0033 0.005 0.0038 0.0029 0.0044 0.0034 0.0031 0.0035 0.0041 0.003 0.0018 0.0027 0.004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.0571 10.2748 10.4834 15.5538 13.0394 24.4108 20.4529 24.1028 21.5029 19.8597
Translational Efficiency 1.4531 0.9315 1.1484 0.8885 0.7763 0.8771 0.916 0.6277 0.9063 1.1304

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
202 1164 1957 1510 1810 1826 1893 1687 2012 2990 3850 3197

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 590.26 776.06 845.70 797.02 701.36 857.03 822.81 820.64 690.21 825.51 834.45 809.48
Standard Deviation 81.58 106.41 108.18 111.55 88.64 119.96 114.61 189.19 94.08 121.47 111.97 157.81
Intensity Change Log 2 — 0.394818 0.518795 0.433265 — 0.289191 0.230404 0.226594 — 0.338423 0.369379 0.324727

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000561 0.004807 0.005662 0.018107 0.001248 0.002260 0.007972 0.005186 0.001179 0.003251 0.006798 0.011289
Bud Neck 0.012478 0.006111 0.009968 0.021212 0.007269 0.009657 0.027264 0.019488 0.007792 0.008276 0.018472 0.020303
Bud Site 0.010159 0.024775 0.056816 0.080951 0.008346 0.012363 0.059919 0.083651 0.008528 0.017195 0.058342 0.082376
Cell Periphery 0.001398 0.000471 0.000241 0.000511 0.000343 0.000550 0.000642 0.000960 0.000449 0.000519 0.000438 0.000748
Cytoplasm 0.003986 0.007362 0.014238 0.038948 0.009981 0.007738 0.029183 0.035522 0.009379 0.007592 0.021586 0.037140
Cytoplasmic Foci 0.057518 0.062450 0.056733 0.098692 0.089666 0.070773 0.091041 0.067282 0.086438 0.067533 0.073602 0.082117
Eisosomes 0.000107 0.000138 0.000096 0.000224 0.000161 0.000172 0.000306 0.000152 0.000156 0.000159 0.000200 0.000186
Endoplasmic Reticulum 0.000866 0.000513 0.001299 0.004396 0.000811 0.000356 0.003391 0.001578 0.000816 0.000417 0.002328 0.002909
Endosome 0.043223 0.100929 0.087341 0.093124 0.064598 0.090085 0.110186 0.103593 0.062452 0.094306 0.098574 0.098648
Golgi 0.085991 0.167295 0.095701 0.083223 0.192132 0.159867 0.089459 0.093132 0.181476 0.162759 0.092632 0.088452
Lipid Particles 0.008937 0.001253 0.000712 0.010078 0.008866 0.005240 0.011906 0.009294 0.008873 0.003688 0.006216 0.009665
Mitochondria 0.700713 0.528417 0.462096 0.265906 0.548603 0.542857 0.320705 0.388538 0.563874 0.537235 0.392576 0.330617
Mitotic Spindle 0.009312 0.013816 0.077810 0.058294 0.007653 0.011222 0.072604 0.044430 0.007820 0.012232 0.075250 0.050978
None 0.000324 0.000201 0.000233 0.000999 0.000857 0.000846 0.001553 0.001596 0.000803 0.000595 0.000882 0.001314
Nuclear Periphery 0.000179 0.000124 0.000426 0.001637 0.000209 0.000084 0.001143 0.000641 0.000206 0.000099 0.000779 0.001111
Nuclear Periphery Foci 0.000322 0.000332 0.000376 0.002186 0.000417 0.000213 0.001263 0.001657 0.000408 0.000259 0.000812 0.001907
Nucleolus 0.001891 0.000333 0.000733 0.002621 0.000693 0.001354 0.003100 0.002840 0.000814 0.000957 0.001896 0.002736
Nucleus 0.003472 0.000782 0.002135 0.013553 0.001059 0.001845 0.012701 0.007262 0.001301 0.001431 0.007330 0.010233
Peroxisomes 0.043950 0.049068 0.043854 0.075660 0.030726 0.047416 0.049077 0.049312 0.032054 0.048059 0.046422 0.061757
Vacuole 0.005391 0.016854 0.061338 0.106652 0.010629 0.020738 0.084045 0.059125 0.010103 0.019226 0.072503 0.081573
Vacuole Periphery 0.009220 0.013971 0.022191 0.023026 0.015734 0.014364 0.022541 0.024762 0.015080 0.014211 0.022363 0.023942

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.83 -7.35 -8.93 -6.20 -5.99 -2.30 -6.80 -5.35 -3.56 2.29 -4.69 -9.28 -9.97 -7.38 -3.81
Bud Neck 1.75 0.56 -2.39 -8.88 -6.16 -1.48 -8.59 -6.09 -4.92 2.90 -0.37 -7.02 -8.07 -8.91 -1.20
Bud Site -3.64 -11.13 -14.06 -12.67 -5.07 -3.08 -18.06 -18.08 -16.77 -4.76 -6.54 -24.47 -25.44 -21.53 -6.94
Cell Periphery 1.02 1.27 0.98 -0.51 -6.82 -1.19 -2.58 -2.84 -1.49 -1.35 -0.49 0.13 -1.97 -1.44 -2.46
Cytoplasm -1.62 -5.37 -11.98 -12.17 -9.65 1.85 -9.79 -9.76 -11.09 -2.10 1.62 -9.28 -14.42 -16.50 -7.94
Cytoplasmic Foci -0.49 0.30 -5.16 -8.88 -11.09 5.38 -0.50 6.01 0.81 6.38 6.33 4.28 1.21 -5.66 -3.35
Eisosomes -2.23 1.07 -6.28 -4.82 -8.03 -0.74 -2.68 0.62 1.34 2.85 -0.24 -1.57 -2.36 -2.32 0.49
Endoplasmic Reticulum 0.83 -1.16 -4.49 -5.78 -4.40 3.32 -4.66 -3.56 -6.47 3.14 3.11 -5.15 -5.99 -7.50 -1.27
Endosome -7.57 -6.21 -6.63 1.74 -1.06 -6.28 -10.47 -8.94 -2.72 1.28 -9.30 -11.01 -10.42 -0.96 0.09
Golgi -7.01 -0.85 0.43 12.68 2.77 4.56 16.81 15.72 11.47 -0.88 3.05 16.54 17.13 17.08 1.29
Lipid Particles 3.51 3.73 -0.55 -6.89 -7.28 2.68 -1.88 -0.33 -2.92 1.53 4.65 2.13 -0.74 -6.11 -3.21
Mitochondria 6.62 9.69 17.72 21.02 18.08 0.51 21.48 14.24 13.69 -6.14 2.67 18.71 24.86 24.68 7.87
Mitotic Spindle -1.14 -13.39 -9.25 -10.98 3.75 -2.31 -16.58 -11.93 -10.74 5.83 -3.28 -24.27 -16.80 -15.44 6.86
None 1.38 1.17 -2.05 -3.34 -3.20 0.02 -1.19 -1.48 -1.79 -0.17 0.49 -0.15 -1.23 -2.72 -1.83
Nuclear Periphery 0.49 -2.05 -4.05 -4.29 -3.32 1.48 -3.28 -2.76 -4.13 1.65 1.34 -3.64 -4.69 -5.61 -1.39
Nuclear Periphery Foci -0.01 -0.66 -3.32 -3.23 -3.14 1.61 -2.26 -3.14 -3.74 -0.82 1.12 -2.09 -4.42 -4.92 -2.86
Nucleolus 1.17 1.04 0.36 -3.36 -2.82 -1.27 -3.56 -3.28 -2.54 -0.13 -0.03 -1.73 -3.07 -3.90 -1.92
Nucleus 1.53 0.52 -4.56 -7.96 -6.84 -1.79 -8.86 -6.32 -5.19 3.39 -0.36 -8.67 -9.59 -9.36 -2.68
Peroxisomes -0.64 0.02 -3.81 -4.70 -6.51 -4.84 -5.50 -5.28 -0.44 -0.03 -5.39 -5.35 -9.39 -4.00 -4.87
Vacuole -5.79 -18.93 -21.52 -19.37 -8.86 -6.01 -21.24 -17.43 -12.77 5.95 -7.16 -27.88 -26.69 -22.68 -2.75
Vacuole Periphery -2.04 -5.53 -5.51 -4.71 -0.25 1.02 -4.19 -5.51 -6.22 -1.31 0.76 -5.85 -6.72 -7.75 -1.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Aim36

Aim36


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aim36-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available