Standard name
Human Ortholog
Description Putative metal transporter involved in mitochondrial iron accumulation; MMT1 has a paralog, MMT2, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0
Bud 0 0 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0 0.09 0.05 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0.08 0 0 0 0 0 0
Cytoplasm 0.09 0.25 0.16 0.16 0.16 0.08 0.06 0.08 0.07 0 0 0 0.46 0.33 0.38 0.22 0.3 0.25 0 0.06 0 0.05 0.07 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0.05 0.06 0 0 0 0 0 0 0
Endosome 0.1 0 0.07 0 0.08 0 0 0 0 0 0 0 0.05 0.09 0.1 0.16 0.12 0.11 0.09 0.07 0.08 0.08 0.09 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.09 0.18 0.05 0.07 0.16 0 0 0 0 0 0
Mitochondria 0.74 0.69 0.65 0.79 0.7 0.9 0.93 0.88 0.94 0.95 0.94 0.98 0.25 0.37 0.29 0.14 0.17 0.1 0.67 0.6 0.66 0.61 0.57 0.59
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.06 0 0.08 0 0 0 0 0 0 0 0 0 0 0.05 0 0.16 0.12 0.07 0.05 0 0.07 0.06 0.06 0
SpindlePole 0 0 0.1 0 0.05 0 0 0.05 0 0 0 0 0 0 0 0.16 0.08 0.19 0 0 0 0 0 0
Vac/Vac Membrane 0.18 0.13 0 0 0.12 0 0.05 0 0 0 0 0 0.12 0.15 0.14 0.11 0.1 0.11 0 0.06 0 0.06 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 6 1 0 0 0 0 0 0 0 1 1 9 9 6 1 1 0 12 20 12 7 23 22
Bud 5 9 16 13 4 21 10 23 23 15 11 15 5 2 2 7 6 4 7 12 1 5 13 13
Bud Neck 1 0 4 0 0 1 0 0 0 0 0 0 2 1 1 0 1 0 2 4 3 5 5 13
Bud Site 0 0 0 1 0 10 3 9 10 11 11 9 1 0 0 3 0 0 – – – – – –
Cell Periphery 10 10 5 5 3 1 1 4 3 0 4 1 3 9 8 7 7 8 0 1 1 0 1 3
Cytoplasm 41 90 48 52 48 40 34 58 30 23 19 17 103 81 79 18 36 27 9 23 11 18 39 24
Endoplasmic Reticulum 7 8 3 4 1 2 4 3 2 2 3 1 13 7 2 4 7 4 1 3 2 2 4 4
Endosome 44 10 22 11 25 2 3 6 1 1 0 0 12 22 20 13 15 12 44 29 30 32 47 38
Golgi 9 2 4 2 1 0 0 1 0 0 0 0 13 23 37 4 9 17 20 12 10 4 10 17
Mitochondria 323 251 199 264 214 429 492 615 423 488 440 538 56 91 60 11 20 11 338 243 245 235 309 332
Nucleus 3 2 2 0 4 7 7 11 9 8 3 5 0 3 1 3 6 7 1 1 0 1 0 0
Nuclear Periphery 10 5 0 8 4 9 20 11 23 18 19 23 0 0 0 0 2 2 5 2 1 5 2 4
Nucleolus 5 1 1 4 3 15 22 34 11 15 10 20 0 0 0 1 1 0 2 0 0 1 3 2
Peroxisomes 26 10 23 8 13 4 3 14 3 5 2 2 2 13 7 13 15 7 24 8 26 21 32 21
SpindlePole 14 4 32 14 15 19 11 36 13 15 15 13 9 8 5 13 10 20 10 7 7 11 16 21
Vac/Vac Membrane 79 47 13 13 36 16 27 29 18 19 17 15 28 37 29 9 12 12 16 25 5 21 22 31
Unique Cell Count 438 365 305 333 306 478 528 699 452 516 470 550 224 243 210 81 120 106 503 406 370 383 547 559
Labelled Cell Count 577 455 373 399 371 576 637 854 569 620 555 660 256 306 257 107 148 131 503 406 370 383 547 559


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 5.1 4.7 4.3 4.4 3.6 3.5 4.0 3.8 3.5 3.7 3.8 5.9 6.1 6.8 5.3 5.9 6.8 5.7 6.1 6.5
Std Deviation (1e-4) 1.5 1.2 1.2 1.1 1.7 1.3 1.4 1.2 1.3 1.1 1.1 1.1 1.2 1.3 1.5 1.5 1.8 2.1 1.4 1.7 2.0
Intensity Change (Log2) – – – -0.12 -0.08 -0.4 -0.41 -0.23 -0.31 -0.41 -0.33 -0.29 0.33 0.39 0.54 0.19 0.34 0.54 0.29 0.39 0.46

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 -1.8 -2.9 -2.6 0 -0.1 -0.6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 1.5 1.5 0 0 0
Cytoplasm 0 0 -3.2 -4.3 -3.5 -4.0 -5.6 -5.7 -6.7 7.6 4.8 5.7 1.4 3.3 2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 3.2 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 -0.9 0.8 0.9 2.5 1.7 1.3
Golgi 0 0 0 0 0 0 0 0 0 2.9 4.4 6.7 0 0 5.9
Mitochondria 0 0 0 0 0 0 0 0 0 -9.2 -6.5 -8.2 -8.3 -9.0 -9.7
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 -3.6 -1.0 -2.0 2.3 1.6 -0.3
SpindlePole 0 0 0 0 0 0 0 0 0 -2.8 -3.2 -3.5 1.4 -0.7 2.2
Vacuole -0.2 3.4 -0.7 0.6 -0.1 -0.2 -0.4 -0.5 -1.2 3.5 4.4 3.9 0 2.3 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.1038 1.8394 1.5278 1.3111 0.8894 1.6393 3.8542 3.5989 3.8325 3.9027 3.5139 4.0182 3.7785 3.9938 4.5222 4.0834 3.9782 3.6908
Actin 0.0131 0.0165 0.0047 0.0129 0.0037 0.0041 0.0554 0.0108 0.016 0.0239 0.0151 0.0162 0.045 0.0197 0.0252 0.0521 0.0198 0.0111
Bud 0.0009 0.0106 0.0026 0.0052 0.0062 0.0022 0.0009 0.002 0.003 0.0015 0.0006 0.0015 0.002 0.0055 0.0034 0.0077 0.0007 0.0017
Bud Neck 0.0007 0.0014 0.0018 0.0066 0.001 0.0024 0.0013 0.0014 0.0033 0.0015 0.0005 0.0019 0.0065 0.0018 0.0016 0.0109 0.0012 0.0027
Bud Periphery 0.0024 0.0175 0.0059 0.0181 0.0331 0.0058 0.0026 0.0048 0.0094 0.0032 0.0022 0.0057 0.0052 0.0126 0.0092 0.0332 0.0021 0.0097
Bud Site 0.0047 0.0268 0.0127 0.0023 0.0014 0.0016 0.0025 0.0325 0.0058 0.0033 0.0005 0.0019 0.0234 0.0533 0.0064 0.0143 0.0029 0.0007
Cell Periphery 0.0034 0.0014 0.0008 0.0013 0.0008 0.0006 0.0011 0.0009 0.0016 0.0005 0.0002 0.0007 0.0033 0.0022 0.0017 0.0055 0.0014 0.0006
Cytoplasm 0.014 0.019 0.0293 0.0697 0.0197 0.0169 0.0127 0.013 0.0121 0.0025 0.0013 0.0109 0.0153 0.0314 0.0207 0.0247 0.024 0.0132
Cytoplasmic Foci 0.0528 0.062 0.0691 0.0311 0.0273 0.0752 0.0403 0.0541 0.0403 0.0429 0.025 0.0493 0.0596 0.0738 0.0473 0.0852 0.0484 0.0651
Eisosomes 0.0009 0.0006 0.0003 0.0003 0.0002 0.0003 0.0026 0.0008 0.001 0.0005 0.0004 0.0006 0.0011 0.0012 0.0012 0.0013 0.0021 0.0008
Endoplasmic Reticulum 0.0036 0.0023 0.0011 0.0041 0.0016 0.0018 0.0018 0.0014 0.0008 0.0003 0.0002 0.0012 0.0073 0.0026 0.0044 0.0007 0.0033 0.0023
Endosome 0.1301 0.0875 0.0663 0.0579 0.0757 0.0803 0.0712 0.0707 0.0347 0.0504 0.0712 0.0464 0.1017 0.0823 0.0866 0.074 0.0975 0.0626
Golgi 0.0498 0.0522 0.0314 0.0338 0.0349 0.0392 0.0427 0.0477 0.0322 0.0573 0.0249 0.0307 0.078 0.066 0.0344 0.0954 0.0418 0.0681
Lipid Particles 0.0375 0.0114 0.0101 0.0039 0.0137 0.0288 0.0476 0.0242 0.01 0.0161 0.0199 0.0195 0.0349 0.0178 0.0159 0.0055 0.0247 0.0217
Mitochondria 0.5751 0.5764 0.6522 0.6799 0.6724 0.6344 0.612 0.5988 0.716 0.7535 0.6651 0.6959 0.5002 0.5199 0.5772 0.4913 0.6091 0.6386
None 0.0489 0.0511 0.0574 0.0475 0.0538 0.0319 0.048 0.0381 0.0572 0.0009 0.0905 0.033 0.0579 0.0444 0.0784 0.0225 0.0381 0.0498
Nuclear Periphery 0.0023 0.0011 0.0005 0.0008 0.0008 0.0011 0.0017 0.0008 0.0004 0.0001 0.0001 0.0004 0.0035 0.0015 0.0027 0.0002 0.0043 0.0003
Nucleolus 0.0008 0.0034 0.0015 0.0006 0.0017 0.0013 0.0005 0.0011 0.0007 0.0001 0.0004 0.0003 0.0009 0.0008 0.0008 0.0004 0.0006 0.0003
Nucleus 0.0012 0.003 0.001 0.0014 0.0039 0.0008 0.0006 0.0006 0.0006 0.0002 0.0002 0.0003 0.0015 0.0012 0.0014 0.0004 0.0011 0.0003
Peroxisomes 0.0384 0.0365 0.0395 0.0084 0.0287 0.0588 0.0468 0.0833 0.0467 0.0374 0.0764 0.077 0.038 0.0505 0.0516 0.0697 0.0685 0.0438
Punctate Nuclear 0.0012 0.005 0.0017 0.0003 0.0052 0.0025 0.0011 0.0004 0.0008 0.0002 0.0004 0.0018 0.0015 0.0005 0.0017 0.0006 0.0024 0.0008
Vacuole 0.0126 0.01 0.0075 0.0095 0.0087 0.006 0.0037 0.0071 0.0051 0.0021 0.0024 0.0025 0.0071 0.0087 0.0133 0.0027 0.0035 0.0031
Vacuole Periphery 0.0054 0.0045 0.0026 0.0044 0.0055 0.0039 0.003 0.0055 0.0023 0.0017 0.0026 0.0022 0.0061 0.0026 0.0149 0.0016 0.0025 0.0026

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.3157 8.3646 7.6392 12.254 16.3312 10.0712 10.4091 9.0014 11.5747 16.0719
Translational Efficiency 1.0553 1.1716 0.9751 0.6068 0.7534 1.2676 0.7685 0.7565 0.6227 0.6478

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
186 1079 874 1363 2309 915 293 170 2495 1994 1167 1533

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 743.46 755.57 896.58 839.63 738.66 766.90 851.92 873.32 739.02 760.77 885.37 843.37
Standard Deviation 77.45 470.21 122.38 132.47 111.73 114.02 120.99 113.40 109.55 354.46 123.56 130.93
Intensity Change Log 2 — 0.023310 0.270177 0.175499 — 0.054128 0.205808 0.241600 — 0.038752 0.238456 0.208821

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.005177 0.002696 0.004889 0.008710 0.001061 0.000593 0.011358 0.011239 0.001368 0.001731 0.006513 0.008990
Bud Neck 0.035528 0.021206 0.026397 0.024932 0.007775 0.041134 0.028215 0.033669 0.009844 0.030350 0.026853 0.025901
Bud Site 0.063695 0.048696 0.074455 0.103288 0.027758 0.017756 0.117283 0.091702 0.030437 0.034498 0.085208 0.102003
Cell Periphery 0.000693 0.000834 0.000287 0.000419 0.001358 0.000500 0.000465 0.000302 0.001308 0.000681 0.000332 0.000406
Cytoplasm 0.082225 0.068994 0.134247 0.161045 0.013657 0.054004 0.156823 0.183384 0.018768 0.062115 0.139915 0.163522
Cytoplasmic Foci 0.158672 0.142343 0.099064 0.091699 0.028195 0.135249 0.084234 0.138754 0.037922 0.139088 0.095341 0.096917
Eisosomes 0.000378 0.000160 0.000100 0.000138 0.000074 0.000191 0.000161 0.000210 0.000097 0.000174 0.000115 0.000146
Endoplasmic Reticulum 0.002130 0.000951 0.006332 0.002316 0.000579 0.000918 0.010454 0.003391 0.000694 0.000936 0.007367 0.002435
Endosome 0.153566 0.077999 0.061680 0.046450 0.052064 0.116590 0.037176 0.062406 0.059631 0.095707 0.055528 0.048220
Golgi 0.052248 0.086926 0.049313 0.046317 0.050417 0.061819 0.019532 0.029900 0.050553 0.075405 0.041836 0.044496
Lipid Particles 0.007443 0.006322 0.005803 0.002694 0.002314 0.021880 0.006725 0.008619 0.002697 0.013461 0.006035 0.003351
Mitochondria 0.150646 0.377172 0.083406 0.158636 0.755625 0.383682 0.081719 0.071499 0.710524 0.380159 0.082983 0.148973
Mitotic Spindle 0.005931 0.024095 0.130318 0.113773 0.007581 0.013569 0.075954 0.046565 0.007458 0.019265 0.116669 0.106320
None 0.000266 0.003149 0.002075 0.001318 0.001074 0.001647 0.001913 0.000760 0.001013 0.002459 0.002034 0.001256
Nuclear Periphery 0.000212 0.000167 0.002370 0.000738 0.000066 0.000800 0.001749 0.000796 0.000077 0.000457 0.002214 0.000745
Nuclear Periphery Foci 0.000445 0.000424 0.002640 0.001738 0.000167 0.000724 0.003005 0.000922 0.000187 0.000562 0.002731 0.001647
Nucleolus 0.001180 0.001289 0.003291 0.001013 0.000248 0.005128 0.001426 0.002189 0.000317 0.003050 0.002823 0.001143
Nucleus 0.041393 0.015197 0.147513 0.037909 0.000960 0.026432 0.150110 0.066815 0.003974 0.020352 0.148165 0.041115
Peroxisomes 0.088583 0.070425 0.049452 0.057529 0.020773 0.053474 0.085745 0.070016 0.025828 0.062647 0.058564 0.058914
Vacuole 0.132536 0.038177 0.103711 0.125737 0.014997 0.047650 0.115570 0.171814 0.023759 0.042524 0.106689 0.130846
Vacuole Periphery 0.017053 0.012780 0.012656 0.013602 0.013260 0.016259 0.010384 0.005046 0.013543 0.014377 0.012085 0.012653

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.83 0.14 -0.77 -4.30 -2.41 1.92 -5.74 -2.23 -2.39 0.60 -0.92 -7.08 -6.39 -6.00 -1.22
Bud Neck 2.52 1.46 2.03 -1.15 0.98 -9.16 -5.79 -4.09 2.21 -0.17 -9.56 -8.37 -8.54 2.39 0.96
Bud Site 1.31 -0.65 -2.45 -7.05 -2.95 3.59 -6.91 -3.54 -4.40 1.99 -1.40 -9.65 -12.39 -11.32 -1.45
Cell Periphery -0.88 2.96 2.34 3.66 -1.19 3.15 3.36 4.16 4.51 3.16 2.44 3.97 3.87 4.17 -0.26
Cytoplasm 1.38 -4.47 -7.96 -14.39 -4.58 -9.34 -11.91 -9.75 -7.43 -1.54 -12.53 -20.99 -26.52 -17.92 -4.59
Cytoplasmic Foci 1.13 5.21 5.94 9.53 1.54 -18.49 -7.57 -8.24 0.47 -3.54 -23.71 -12.70 -13.26 10.21 0.07
Eisosomes 2.58 3.23 2.96 3.04 -2.77 -10.16 -8.61 -4.85 0.22 -0.64 -8.08 -3.15 -4.09 4.28 -1.62
Endoplasmic Reticulum 2.16 -7.18 -1.13 -7.90 8.36 -2.45 -5.79 -3.64 -3.19 4.01 -2.52 -12.47 -9.75 -8.59 8.65
Endosome 4.55 6.08 7.28 10.06 4.38 -11.20 4.85 0.74 7.28 -1.55 -9.21 2.96 6.56 15.43 3.15
Golgi -4.04 1.06 1.82 10.11 1.31 -2.45 9.25 5.30 6.34 -0.74 -6.60 4.52 5.39 11.00 0.29
Lipid Particles 0.49 0.64 2.35 4.04 4.14 -9.38 -5.02 -3.20 5.30 -0.12 -9.81 -5.66 -1.91 9.10 4.48
Mitochondria -10.07 3.56 1.09 19.67 -5.88 27.78 58.00 54.46 20.52 1.05 31.15 74.39 64.69 26.35 -5.75
Mitotic Spindle -7.19 -14.82 -16.63 -12.65 2.16 -3.15 -6.02 -3.37 -2.68 2.16 -7.24 -15.77 -16.80 -14.03 1.73
None -2.78 -3.60 -2.62 1.64 1.02 -1.79 -2.30 0.20 1.97 2.45 -2.54 -2.67 -1.04 1.68 1.32
Nuclear Periphery 1.61 -5.77 -6.63 -8.50 3.33 -4.20 -5.48 -5.73 -1.67 2.04 -4.59 -7.71 -10.23 -5.66 3.79
Nuclear Periphery Foci 0.28 -7.15 -2.92 -3.04 1.94 -2.44 -4.41 -5.63 -1.87 3.06 -3.32 -9.18 -3.86 -2.90 2.64
Nucleolus -0.30 -3.65 0.26 0.96 4.78 -4.90 -4.10 -2.64 2.58 -0.04 -5.80 -7.16 -5.12 3.75 4.76
Nucleus 2.86 -9.49 -1.37 -11.46 12.13 -9.56 -11.85 -8.03 -5.68 4.45 -9.13 -22.64 -17.74 -11.85 13.49
Peroxisomes 1.24 3.42 3.22 4.34 -0.54 -8.18 -5.34 -3.80 -0.10 1.30 -11.14 -6.46 -6.27 3.51 0.68
Vacuole 7.00 1.09 -2.80 -21.62 -7.17 -10.12 -12.07 -11.33 -9.58 -4.07 -7.37 -19.88 -26.67 -23.37 -7.76
Vacuole Periphery 1.13 1.72 1.80 1.48 0.16 -2.17 2.38 7.79 8.58 2.02 -0.74 2.77 3.05 3.67 0.26
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative metal transporter involved in mitochondrial iron accumulation; MMT1 has a paralog, MMT2, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mmt1

Mmt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mmt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available