Standard name
Human Ortholog
Description Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0.14 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0
Cytoplasm 0 0 0.11 0.08 0.1 0.07 0.09 0.1 0 0 0.05 0.07 0.21 0.35 0.45 0.11 0.08 0.15 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0 0.11 0.08 0.16 0.21 0.07 0.05 0 0 0 0 0 0.26 0.24 0.26 0.17 0.2 0.19 0.15 0.12 0.12 0.08 0.09 0.07
Golgi 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0.06 0.05 0 0.08 0 0 0 0
Mitochondria 0.93 0.61 0.18 0.59 0.44 0.72 0.72 0.73 0.86 0.81 0.93 0.87 0.31 0.09 0.12 0.12 0.12 0.14 0.69 0.64 0.7 0.71 0.72 0.69
Nucleus 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0.07 0.06 0.06 0 0 0 0 0 0 0 0 0.07 0.09 0.09 0.11 0.13 0.11 0.05 0.05 0.06 0 0.05 0
SpindlePole 0 0.05 0.29 0.19 0.18 0.07 0.09 0.15 0.08 0.14 0.05 0.06 0.07 0.05 0.06 0.38 0.27 0.28 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.22 0.17 0 0.09 0.12 0.05 0.05 0.06 0.05 0 0.05 0.1 0.09 0.1 0.09 0.18 0.16 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 5 2 3 6 4 1 3 6 1 2 1 0 6 8 0 10 3 6 2 12 4 0 3 7
Bud 1 2 1 6 6 10 5 15 7 13 15 5 1 4 0 14 6 6 0 2 0 0 0 0
Bud Neck 0 0 2 2 1 2 4 2 0 1 1 2 0 0 0 0 3 1 0 1 0 1 1 4
Bud Site 2 1 0 1 0 0 0 5 1 1 0 3 0 0 0 4 1 3 – – – – – –
Cell Periphery 4 16 9 2 3 0 1 3 0 1 3 1 2 4 8 17 16 11 0 0 0 0 0 0
Cytoplasm 6 11 7 11 19 21 25 35 6 9 12 18 29 59 92 31 23 44 1 2 0 4 1 5
Endoplasmic Reticulum 6 19 4 5 5 8 8 3 2 6 3 7 3 7 0 15 11 19 0 2 0 1 1 2
Endosome 4 37 5 23 39 20 14 16 6 5 0 1 35 41 54 48 58 56 34 52 19 15 19 17
Golgi 0 22 2 3 4 0 1 0 0 0 0 0 5 9 4 17 18 14 5 34 3 6 6 10
Mitochondria 205 213 12 84 81 212 200 262 211 174 245 228 42 16 25 35 33 43 162 287 115 139 156 174
Nucleus 2 1 2 1 7 10 15 25 4 8 5 5 2 3 1 13 16 8 0 0 0 0 0 0
Nuclear Periphery 2 3 0 0 0 2 7 1 3 2 3 5 0 0 0 0 1 0 2 4 0 0 2 1
Nucleolus 2 0 0 0 0 0 1 1 1 2 2 2 0 0 0 0 2 0 1 0 0 0 0 0
Peroxisomes 2 24 4 9 5 8 5 9 4 1 0 0 9 16 19 33 36 32 10 22 9 8 11 10
SpindlePole 9 16 19 27 34 21 24 53 19 31 13 16 9 9 12 110 77 83 2 3 2 4 1 1
Vac/Vac Membrane 21 76 11 3 16 35 13 18 15 10 7 13 13 16 20 27 52 49 5 12 6 8 8 10
Unique Cell Count 220 347 66 143 186 296 278 359 244 216 263 261 136 171 204 289 285 297 236 447 165 196 218 252
Labelled Cell Count 271 443 81 183 224 350 326 454 280 266 310 306 156 192 235 374 356 375 236 447 165 196 218 252


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 5.8 5.9 5.5 5.7 4.8 4.8 5.2 4.3 4.4 4.0 4.0 6.3 6.1 5.9 6.4 6.8 6.2 5.7 5.8 6.2
Std Deviation (1e-4) 0.6 1.0 0.9 1.1 1.1 1.3 1.0 1.4 0.9 0.7 1.2 0.9 1.2 1.2 1.2 1.1 1.4 1.4 1.1 1.1 1.5
Intensity Change (Log2) – – – -0.09 -0.04 -0.3 -0.29 -0.17 -0.45 -0.4 -0.55 -0.53 0.09 0.06 0.02 0.12 0.22 0.08 -0.03 -0.03 0.09

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Endosome 1.7 2.5 0 0 0 0 – – 0 3.0 2.9 3.2 1.9 2.4 2.2
Golgi 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Mitochondria 5.5 3.7 0 0 8.5 0 – – 0 1.9 -1.9 -1.2 -1.3 -1.4 -0.8
Nuclear Periphery 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – – 0 0 0.8 0.8 1.3 1.5 1.2
SpindlePole -1.6 -1.8 0 0 -2.8 0 – – 0 -4.3 -5.0 -5.1 1.4 -0.3 -0.1
Vac – – – – – – – – – – – – – – –
Cortical Patches 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cytoplasm -0.7 -0.1 -1.0 -0.4 -0.2 0 – – -1.0 1.9 3.7 5.1 0 -0.7 0.9
Nucleus 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Vacuole 0 -1.8 -1.1 0 0 -2.7 – – 0 -1.5 -1.6 -1.5 -1.7 0.3 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.058 1.6484 1.3672 1.2556 2.1411 1.4068 1.7245 1.3622 1.5229 1.5941 2.0427 1.2587 2.5564 2.1263 2.0458 2.1496 2.8034 2.2672
Actin 0.0392 0.0153 0.0048 0.0106 0.0082 0.0029 0.0505 0.0154 0.0237 0.0069 0.0215 0.0052 0.0872 0.0246 0.0513 0.0453 0.037 0.0599
Bud 0.0013 0.0022 0.0006 0.001 0.0025 0.0003 0.0018 0.0022 0.0018 0.0011 0.0027 0.0009 0.0007 0.0023 0.0071 0.0027 0.0101 0.0007
Bud Neck 0.0088 0.0021 0.0008 0.0003 0.002 0.0004 0.0015 0.0011 0.0032 0.0008 0.0017 0.0023 0.0018 0.0009 0.0008 0.0005 0.0014 0.0014
Bud Periphery 0.0026 0.0026 0.001 0.0022 0.0028 0.0027 0.0041 0.0035 0.0037 0.0017 0.009 0.0012 0.0012 0.0037 0.0125 0.0065 0.0137 0.0024
Bud Site 0.0104 0.0197 0.0032 0.0011 0.0059 0.0005 0.0055 0.0282 0.0252 0.0145 0.0045 0.0007 0.012 0.0351 0.0162 0.0034 0.0267 0.0013
Cell Periphery 0.0023 0.001 0.0003 0.0002 0.0003 0.0004 0.0011 0.002 0.0011 0.0006 0.002 0.0003 0.0004 0.0015 0.0009 0.0003 0.0005 0.0004
Cytoplasm 0.0153 0.0111 0.0053 0.001 0.005 0.0005 0.0131 0.0078 0.0074 0.0008 0.0235 0.0043 0.0228 0.0067 0.0063 0.0016 0.002 0.0047
Cytoplasmic Foci 0.0467 0.042 0.0438 0.0187 0.0607 0.0111 0.0853 0.046 0.0516 0.023 0.0304 0.0265 0.0701 0.0436 0.0462 0.0318 0.0631 0.0344
Eisosomes 0.0025 0.001 0.0004 0.0001 0.0001 0.0002 0.0011 0.0006 0.0005 0.0002 0.0011 0.0003 0.0007 0.0008 0.0012 0.0008 0.0005 0.0009
Endoplasmic Reticulum 0.0064 0.0014 0.0009 0.0002 0.0021 0.0005 0.0051 0.0025 0.0011 0.0009 0.0037 0.0011 0.0133 0.0053 0.0014 0.0006 0.0007 0.0007
Endosome 0.1282 0.1267 0.1016 0.0379 0.1972 0.0247 0.1125 0.0886 0.0624 0.0404 0.1309 0.0775 0.0643 0.0659 0.0539 0.0384 0.0418 0.0629
Golgi 0.079 0.0907 0.0599 0.0355 0.1052 0.0338 0.0592 0.0616 0.0577 0.0259 0.0605 0.0616 0.0615 0.1029 0.0651 0.0641 0.0489 0.1134
Lipid Particles 0.0603 0.0197 0.0418 0.0099 0.0121 0.0257 0.0897 0.0241 0.0318 0.0293 0.0176 0.0295 0.0729 0.0114 0.009 0.0188 0.0699 0.0183
Mitochondria 0.462 0.5996 0.6601 0.8149 0.5512 0.8158 0.4261 0.6457 0.6335 0.8179 0.5566 0.6991 0.4549 0.6177 0.6685 0.7404 0.6308 0.6412
None 0.014 0.0121 0.0083 0.0004 0.0005 0.0004 0.0422 0.0108 0.0111 0.0007 0.0341 0.0184 0.0502 0.0098 0.0288 0.0014 0.0007 0.0005
Nuclear Periphery 0.0129 0.0004 0.001 0.0001 0.0016 0.0002 0.003 0.0011 0.0008 0.0008 0.0252 0.0013 0.0059 0.0007 0.0007 0.0017 0.001 0.0002
Nucleolus 0.0017 0.0006 0.0012 0.0001 0.0003 0.0001 0.0033 0.0014 0.0012 0.0009 0.0022 0.0005 0.0008 0.0004 0.0008 0.0014 0.0018 0.0002
Nucleus 0.013 0.0007 0.0016 0.0001 0.0008 0.0001 0.0074 0.0007 0.001 0.0005 0.0155 0.0008 0.0013 0.0003 0.0009 0.0011 0.001 0.0002
Peroxisomes 0.0759 0.0387 0.0515 0.0614 0.0227 0.0762 0.0581 0.0458 0.0714 0.0243 0.0209 0.059 0.0599 0.0614 0.022 0.0322 0.0373 0.0518
Punctate Nuclear 0.0043 0.0005 0.0022 0.0002 0.0009 0.0001 0.007 0.0007 0.0021 0.0007 0.0025 0.0005 0.0131 0.0006 0.0009 0.0035 0.0043 0.0003
Vacuole 0.0078 0.0073 0.0059 0.0018 0.0103 0.0013 0.0149 0.0062 0.0046 0.0053 0.0238 0.0041 0.0026 0.0026 0.0037 0.0017 0.0046 0.0019
Vacuole Periphery 0.0052 0.0046 0.0037 0.0023 0.0077 0.0019 0.0073 0.004 0.0031 0.0027 0.0097 0.0047 0.0024 0.0018 0.0017 0.0019 0.0022 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.8123 7.3568 3.7793 13.3654 9.4389 8.2251 9.5842 12.1649 13.3048 14.2702
Translational Efficiency 0.6216 0.6493 1.5509 0.5717 0.5718 0.7143 0.6224 0.4848 0.4834 0.4848

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1068 709 965 97 986 1831 122 148 2054 2540 1087 245

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 644.33 738.51 931.36 908.75 702.10 735.95 946.54 914.90 672.06 736.66 933.06 912.47
Standard Deviation 208.77 125.89 123.25 153.07 101.04 97.33 106.64 116.82 168.51 106.08 121.60 132.40
Intensity Change Log 2 — 0.196818 0.531539 0.496084 — 0.067931 0.430987 0.381938 — 0.131047 0.479981 0.437690

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001124 0.009539 0.010318 0.040920 0.001250 0.000456 0.015407 0.027061 0.001184 0.002991 0.010889 0.032548
Bud Neck 0.058324 0.012118 0.012437 0.013507 0.005519 0.005622 0.020541 0.017587 0.032976 0.007435 0.013347 0.015972
Bud Site 0.058378 0.032031 0.056283 0.130128 0.010014 0.009180 0.036396 0.164240 0.035161 0.015559 0.054051 0.150734
Cell Periphery 0.000926 0.000487 0.000257 0.001257 0.000879 0.000186 0.000382 0.000402 0.000903 0.000270 0.000271 0.000741
Cytoplasm 0.068335 0.008583 0.010647 0.035649 0.004575 0.004703 0.012304 0.031229 0.037728 0.005786 0.010833 0.032979
Cytoplasmic Foci 0.163515 0.083320 0.085123 0.150380 0.067480 0.060849 0.132140 0.092250 0.117415 0.067122 0.090400 0.115265
Eisosomes 0.000260 0.000200 0.000122 0.000177 0.000100 0.000058 0.000183 0.000190 0.000183 0.000098 0.000129 0.000185
Endoplasmic Reticulum 0.001404 0.000805 0.005086 0.006030 0.000497 0.000312 0.006346 0.003174 0.000968 0.000450 0.005227 0.004305
Endosome 0.076287 0.118342 0.092978 0.099436 0.120678 0.118278 0.152766 0.080308 0.097596 0.118296 0.099688 0.087881
Golgi 0.067527 0.136115 0.100382 0.089014 0.154080 0.144142 0.052778 0.107251 0.109076 0.141902 0.095039 0.100031
Lipid Particles 0.014564 0.003721 0.003022 0.004432 0.004127 0.002648 0.015746 0.001731 0.009554 0.002948 0.004450 0.002800
Mitochondria 0.340343 0.418492 0.239869 0.097823 0.523343 0.549418 0.105111 0.136058 0.428190 0.512872 0.224744 0.120920
Mitotic Spindle 0.010682 0.037305 0.188397 0.093103 0.017425 0.025716 0.155226 0.131328 0.013919 0.028951 0.184674 0.116194
None 0.003972 0.000315 0.000327 0.000118 0.000527 0.000815 0.000414 0.000180 0.002319 0.000675 0.000336 0.000155
Nuclear Periphery 0.000566 0.000186 0.000775 0.000249 0.000185 0.000183 0.001289 0.000638 0.000383 0.000184 0.000832 0.000484
Nuclear Periphery Foci 0.000871 0.000608 0.001720 0.001395 0.000329 0.000285 0.008439 0.001148 0.000611 0.000375 0.002474 0.001246
Nucleolus 0.002847 0.000799 0.003108 0.000517 0.000892 0.000965 0.012265 0.000590 0.001909 0.000919 0.004136 0.000561
Nucleus 0.015089 0.001781 0.012423 0.002358 0.000645 0.001016 0.022713 0.007280 0.008156 0.001230 0.013578 0.005331
Peroxisomes 0.066077 0.097720 0.076978 0.139632 0.046903 0.035870 0.164357 0.129791 0.056873 0.053135 0.086785 0.133687
Vacuole 0.031202 0.022730 0.072423 0.079201 0.020211 0.021525 0.067708 0.057676 0.025926 0.021861 0.071894 0.066198
Vacuole Periphery 0.017705 0.014804 0.027326 0.014674 0.020341 0.017770 0.017489 0.009889 0.018970 0.016942 0.026222 0.011784

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.32 -7.46 -3.79 -2.92 -2.85 3.00 -2.50 -3.94 -4.06 -1.31 -3.14 -7.74 -5.45 -5.11 -3.59
Bud Neck 10.68 11.35 9.36 -0.41 -0.13 -0.10 -1.93 -3.77 -3.75 0.19 11.17 7.53 4.88 -3.74 -1.10
Bud Site 5.35 0.02 -3.66 -5.04 -3.68 0.50 -3.76 -9.02 -9.07 -6.73 8.02 -5.65 -8.92 -10.50 -7.23
Cell Periphery 3.47 5.83 -0.39 -1.10 -1.47 2.55 1.72 1.78 -3.91 -0.07 4.41 4.41 0.71 -1.72 -1.71
Cytoplasm 14.94 14.21 3.39 -3.08 -2.76 -0.14 -2.14 -6.74 -6.72 -3.60 14.17 10.86 0.39 -6.71 -5.32
Cytoplasmic Foci 11.86 12.38 0.82 -3.48 -3.48 1.71 -5.16 -2.31 -3.10 2.88 12.76 6.16 0.60 -4.84 -2.40
Eisosomes 1.33 5.79 2.72 0.55 -2.37 4.75 -3.54 -3.21 -4.96 0.08 5.10 3.68 0.01 -4.09 -2.72
Endoplasmic Reticulum 1.53 -5.12 -1.58 -1.79 -0.15 1.75 -3.70 -3.07 -3.26 1.74 2.59 -6.69 -2.69 -3.11 0.86
Endosome -6.27 -2.87 -1.40 1.60 -0.29 0.35 -1.61 4.37 4.44 4.00 -4.58 -0.03 1.80 4.32 1.75
Golgi -9.17 -4.94 -1.04 3.11 0.85 1.31 10.56 3.83 3.31 -3.09 -6.32 2.89 1.56 4.62 0.02
Lipid Particles 6.59 7.34 4.80 -0.75 -1.10 1.45 -2.89 2.03 0.87 3.40 6.78 4.37 5.86 -0.26 1.92
Mitochondria -4.72 7.60 10.65 13.16 6.21 -1.82 19.72 18.80 21.58 -0.96 -8.02 17.81 20.10 26.13 6.65
Mitotic Spindle -6.42 -21.65 -3.92 -2.58 4.41 -2.72 -5.83 -6.23 -5.78 0.74 -6.57 -22.00 -7.39 -6.27 4.37
None 4.51 4.50 4.76 2.88 6.27 -0.48 -0.29 1.35 1.20 1.66 2.85 4.42 4.91 1.35 5.00
Nuclear Periphery 1.58 -1.24 0.56 -1.13 2.28 0.05 -3.10 -1.83 -1.84 1.57 1.54 -3.39 -0.85 -2.15 1.87
Nuclear Periphery Foci 0.77 -2.50 -1.15 -1.83 0.68 0.31 -2.40 -1.96 -2.03 2.15 1.31 -4.10 -1.99 -2.86 2.34
Nucleolus 3.56 -0.40 2.98 0.00 2.63 -0.39 -1.94 0.27 0.57 1.96 2.05 -2.30 2.85 0.52 3.47
Nucleus 6.77 0.44 5.43 -1.20 3.93 -0.90 -3.46 -2.44 -2.35 1.72 6.66 -2.74 0.09 -2.56 2.06
Peroxisomes -4.02 -1.68 -3.21 -1.77 -2.71 2.35 -5.47 -4.25 -4.96 1.50 0.94 -5.03 -5.15 -5.42 -2.89
Vacuole 2.61 -9.92 -3.68 -4.16 -1.14 -0.61 -5.02 -5.13 -5.05 -0.53 2.18 -12.75 -6.13 -6.55 -1.20
Vacuole Periphery 1.30 -3.60 0.74 0.16 2.49 1.33 0.97 3.82 3.32 1.85 1.45 -3.04 3.03 2.34 4.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
Localization
Cell Percentages mitochondrion (80%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Aep2

Aep2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aep2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available