Standard name
Human Ortholog
Description Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0
Cytoplasm 0.97 0.98 0.99 0.98 0.96 0.89 0.82 0.78 0.65 0.65 0.53 0.56 1.0 0.99 1.0 0.98 0.98 0.95 0.95 0.94 0.93 0.91 0.9 0.88
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0 0 0.11 0.07 0.35 0.4 0.41 0.55 0.6 0.7 0.67 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 1 0 0 0 1 0 2 2
Bud 4 1 1 0 1 6 7 4 5 4 7 10 0 0 1 1 0 0 0 0 1 0 6 2
Bud Neck 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 2
Bud Site 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 10 1 2 4 1 7 2 4 8 3 9 5 8 12 6 3 13 0 0 0 0 0 0
Cytoplasm 216 429 242 170 242 317 439 319 191 275 173 243 384 394 512 240 144 140 217 422 232 102 296 242
Endoplasmic Reticulum 0 3 1 0 1 0 0 2 5 2 2 0 0 2 1 14 5 8 1 1 2 0 2 4
Endosome 0 1 0 1 1 2 2 4 0 1 0 0 0 1 0 0 0 0 1 5 0 1 1 0
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 1
Mitochondria 17 6 2 20 17 125 212 166 161 256 227 288 0 1 0 9 3 3 2 5 5 2 4 6
Nucleus 0 0 0 1 0 3 0 0 0 1 1 1 0 0 1 0 2 0 0 0 0 0 1 0
Nuclear Periphery 2 0 0 0 0 0 2 1 0 1 0 1 1 0 1 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 4 4 1 1 3 5 0 1 0 0 0 0 0 1 0 0 1 1
Vac/Vac Membrane 0 3 2 0 3 2 8 2 0 2 5 1 0 1 0 2 1 1 1 6 1 1 2 6
Unique Cell Count 223 439 245 174 252 358 534 407 294 426 324 432 385 399 514 246 147 147 228 447 250 113 329 275
Labelled Cell Count 239 453 250 194 269 456 681 507 369 551 422 559 391 408 528 274 159 166 228 447 250 113 329 275


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 5.5 4.8 4.4 4.5 3.8 3.5 3.9 3.4 3.2 3.2 3.2 5.6 5.5 5.3 6.6 7.5 7.7 5.3 5.7 6.5
Std Deviation (1e-4) 0.5 0.7 0.9 1.3 1.1 1.0 1.0 1.6 0.6 0.9 0.9 1.3 1.1 1.3 1.1 1.1 1.2 1.3 1.3 1.7 1.6
Intensity Change (Log2) – – – -0.11 -0.08 -0.32 -0.45 -0.29 -0.49 -0.56 -0.56 -0.58 0.23 0.2 0.16 0.47 0.66 0.69 0.17 0.27 0.44


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.4
Cytoplasm -0.8 -1.9 -4.7 -6.5 -7.3 -9.8 -10.1 -12.1 -11.8 1.5 0 1.3 -1.0 -0.6 -2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.4 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 2.1 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.7223 0.9018 0.6984 0.7576 0.075 0.5399 2.3851 2.5909 2.2788 1.9725 2.6809 2.418 5.0463 3.5458 4.1477 2.5359 2.5408 2.9492
Actin 0.2813 0.0002 0.0107 0.091 0.0003 0.014 0.0551 0.0213 0.0082 0.0118 0.0095 0.0083 0.0584 0.0043 0.0099 0.0005 0.0141 0.018
Bud 0.0016 0.0001 0.0005 0.0009 0.0002 0.0001 0.0024 0.0063 0.0027 0.0043 0.0029 0.0014 0.0115 0.0003 0.03 0.0001 0.0022 0.0004
Bud Neck 0.006 0.0001 0.0006 0.0015 0.0002 0.0027 0.002 0.0003 0.0005 0.0005 0.0002 0.0035 0.0027 0.0004 0.0008 0.0001 0.0023 0.001
Bud Periphery 0.0023 0 0.0007 0.0011 0.0001 0.0002 0.0038 0.008 0.0037 0.0142 0.0107 0.0028 0.0572 0.0003 0.0088 0.0001 0.0035 0.0004
Bud Site 0.0467 0.0004 0.0029 0.0041 0.0001 0.0001 0.0136 0.0207 0.0113 0.0024 0.0008 0.0002 0.0058 0.0113 0.0171 0.0003 0.0012 0.0004
Cell Periphery 0.0014 0.0004 0.0005 0.0003 0.0001 0.0002 0.0007 0.0005 0.0003 0.0003 0.0003 0.0002 0.0014 0.0004 0.0008 0.0002 0.0001 0.0001
Cytoplasm 0.2976 0.5694 0.564 0.363 0.7494 0.5758 0.2087 0.3828 0.3159 0.4051 0.2651 0.3796 0.1752 0.4903 0.2463 0.3793 0.5525 0.4621
Cytoplasmic Foci 0.0233 0.0042 0.0184 0.013 0.0098 0.0064 0.038 0.0261 0.0179 0.0312 0.0117 0.0154 0.0785 0.0167 0.0252 0.0094 0.0078 0.0222
Eisosomes 0.0038 0.0001 0.0002 0.0005 0 0.0009 0.0008 0.0003 0.0002 0.0002 0.0004 0.0001 0.0007 0.0003 0.0007 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0352 0.0049 0.0081 0.0026 0.0026 0.0051 0.0099 0.0018 0.0031 0.0023 0.0042 0.0017 0.0044 0.0058 0.0035 0.0038 0.0034 0.0022
Endosome 0.0076 0.0024 0.0224 0.0137 0.0033 0.004 0.0416 0.0047 0.0219 0.0236 0.0144 0.0151 0.0138 0.0063 0.014 0.0048 0.0056 0.0031
Golgi 0.0163 0.0002 0.0076 0.0208 0.0003 0.0014 0.0132 0.0041 0.019 0.0138 0.0044 0.0022 0.0059 0.0016 0.0052 0.0002 0.0006 0.0014
Lipid Particles 0.0145 0.0005 0.0202 0.0161 0.0001 0.004 0.0204 0.0007 0.0095 0.0057 0.0011 0.0013 0.017 0.0036 0.0066 0.0009 0.0003 0.001
Mitochondria 0.0048 0.0001 0.0375 0.0818 0.0001 0.0007 0.0112 0.0289 0.0168 0.0085 0.1651 0.0013 0.0015 0.001 0.0069 0.0002 0.0016 0.001
None 0.2352 0.4124 0.2756 0.3752 0.2314 0.3734 0.5193 0.4817 0.5489 0.4563 0.4517 0.5505 0.4896 0.4455 0.608 0.5947 0.3643 0.4832
Nuclear Periphery 0.0033 0.0009 0.0012 0.001 0.0003 0.0029 0.0117 0.0005 0.001 0.0027 0.0386 0.0072 0.0028 0.0008 0.0017 0.001 0.0084 0.0005
Nucleolus 0.0007 0.0001 0.0002 0.0002 0 0.0004 0.001 0.0001 0.0002 0.0003 0.0003 0.0001 0.0012 0.0003 0.0012 0.0001 0.0014 0.0001
Nucleus 0.0013 0.0009 0.0009 0.0006 0.0004 0.0018 0.0188 0.0007 0.0008 0.0011 0.0071 0.0005 0.004 0.0011 0.0019 0.0009 0.0207 0.0003
Peroxisomes 0.0105 0 0.0148 0.0092 0 0.0016 0.0159 0.0084 0.0147 0.0101 0.0015 0.0059 0.046 0.0061 0.0053 0.0001 0.0005 0.0009
Punctate Nuclear 0.0051 0.0004 0.0006 0.0011 0.0002 0.0032 0.0043 0.0007 0.001 0.0027 0.0014 0.0004 0.0206 0.0018 0.0033 0.0006 0.0074 0.0008
Vacuole 0.001 0.0022 0.0107 0.0016 0.001 0.001 0.0056 0.0012 0.0019 0.0018 0.0035 0.0013 0.0013 0.0015 0.0022 0.0022 0.0015 0.0007
Vacuole Periphery 0.0004 0.0002 0.0016 0.0006 0.0001 0.0003 0.0021 0.0003 0.0007 0.001 0.0052 0.0009 0.0003 0.0002 0.0006 0.0003 0.0005 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.7979 8.3158 7.5946 8.0359 5.5666 7.1517 8.2464 9.3854 7.9752 8.788
Translational Efficiency 0.9181 0.5686 0.7611 0.5701 0.5238 0.7567 0.7714 0.5901 0.6953 0.5715

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2298 1702 1431 2327 1747 135 2030 1231 4045 1837 3461 3558

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.23 749.99 898.60 878.11 745.65 848.36 839.07 879.46 737.46 757.22 863.68 878.58
Standard Deviation 82.06 121.81 112.55 108.15 120.45 99.79 110.38 128.99 100.71 123.04 115.08 115.79
Intensity Change Log 2 — 0.036546 0.297354 0.264076 — 0.186178 0.170293 0.238119 — 0.114031 0.234602 0.251030

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000082 0.000404 0.000220 0.001930 0.000407 0.001476 0.000067 0.001286 0.000222 0.000483 0.000130 0.001707
Bud Neck 0.013852 0.025972 0.002814 0.007411 0.015029 0.018464 0.002610 0.009471 0.014361 0.025420 0.002694 0.008124
Bud Site 0.008272 0.030028 0.009989 0.033330 0.011383 0.033906 0.003922 0.066965 0.009616 0.030313 0.006430 0.044967
Cell Periphery 0.000142 0.000122 0.000108 0.000132 0.001447 0.000172 0.000168 0.000131 0.000706 0.000126 0.000143 0.000132
Cytoplasm 0.587788* 0.495423* 0.577355* 0.638691* 0.565473* 0.334782* 0.629244* 0.505909* 0.578150* 0.483618* 0.607790* 0.592751*
Cytoplasmic Foci 0.165957 0.206004* 0.018814 0.013452 0.192147* 0.271207* 0.029823 0.026664 0.177269 0.210796* 0.025271 0.018023
Eisosomes 0.000102 0.000089 0.000035 0.000020 0.002829 0.000172 0.000057 0.000033 0.001280 0.000095 0.000048 0.000025
Endoplasmic Reticulum 0.001279 0.000817 0.001905 0.000512 0.001550 0.000727 0.000394 0.001159 0.001396 0.000810 0.001019 0.000735
Endosome 0.018378 0.034059 0.003367 0.004049 0.018650 0.067230 0.003847 0.023527 0.018495 0.036497 0.003648 0.010788
Golgi 0.003508 0.008158 0.000127 0.002201 0.004610 0.012141 0.000284 0.018417 0.003984 0.008451 0.000219 0.007811
Lipid Particles 0.004346 0.003412 0.001210 0.000540 0.005679 0.004504 0.001438 0.001201 0.004922 0.003493 0.001344 0.000769
Mitochondria 0.001704 0.004760 0.000664 0.002761 0.003577 0.002764 0.000300 0.008147 0.002513 0.004613 0.000451 0.004624
Mitotic Spindle 0.000201 0.002541 0.005547 0.076096 0.002215 0.006944 0.004888 0.089842 0.001071 0.002865 0.005161 0.080852
None 0.003343 0.002835 0.005244 0.004943 0.018316 0.006273 0.006906 0.005073 0.009810 0.003088 0.006219 0.004988
Nuclear Periphery 0.000170 0.000232 0.001343 0.000801 0.000444 0.000150 0.000488 0.001078 0.000289 0.000226 0.000841 0.000897
Nuclear Periphery Foci 0.000312 0.000357 0.001904 0.000410 0.000617 0.000845 0.000519 0.001161 0.000444 0.000393 0.001091 0.000670
Nucleolus 0.000763 0.001220 0.000327 0.000263 0.000513 0.000474 0.000476 0.000933 0.000655 0.001165 0.000414 0.000495
Nucleus 0.056032 0.033700 0.264788* 0.127960 0.044762 0.017904 0.198837* 0.061521 0.051165 0.032539 0.226105* 0.104973
Peroxisomes 0.001560 0.007499 0.000830 0.002730 0.006654 0.019707 0.000257 0.002478 0.003760 0.008396 0.000494 0.002643
Vacuole 0.129913 0.138617 0.103247 0.080640 0.101605 0.197103 0.114846 0.153928 0.117687 0.142915 0.110050 0.105996
Vacuole Periphery 0.002293 0.003750 0.000163 0.001128 0.002092 0.003055 0.000630 0.021077 0.002206 0.003699 0.000437 0.008030

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.25 -7.69 -3.89 -1.75 -2.59 -1.91 1.54 -0.52 1.79 -4.17 -2.22 0.66 -2.89 -1.27 -4.35
Bud Neck -6.86 10.66 8.61 12.51 -3.52 -0.94 13.38 8.38 4.17 -4.77 -6.96 17.31 12.08 13.10 -6.52
Bud Site -11.63 0.69 -4.25 6.71 -3.82 -3.70 6.59 -5.96 0.42 -8.76 -11.46 5.42 -7.00 4.58 -9.74
Cell Periphery 1.79 5.30 6.68 2.64 2.37 4.61 4.75 4.95 2.75 4.87 4.86 4.87 5.22 3.19 5.18
Cytoplasm 10.92 13.81 7.66 -3.82 -6.96 9.23 -2.33 9.23 -5.08 11.41 12.15 6.87 11.27 -2.94 4.01
Cytoplasmic Foci -6.73 43.73 46.34 41.27 4.42 -4.08 36.50 39.53 14.51 8.78 -5.98 55.70 60.75 43.31 11.69
Eisosomes 2.47 14.16 20.46 13.12 9.25 4.71 4.93 4.96 4.44 7.05 4.86 5.04 5.12 13.11 12.68
Endoplasmic Reticulum 2.60 -9.21 3.09 0.03 15.34 2.61 3.86 1.77 -1.67 -5.54 3.48 -1.76 3.44 -0.87 9.67
Endosome -8.38 17.36 18.74 19.59 4.60 -4.38 14.36 8.03 5.49 -3.35 -9.64 21.92 19.69 18.69 -0.48
Golgi -7.03 16.76 9.78 11.52 -2.35 -2.09 13.93 -0.28 1.87 -4.02 -6.73 21.02 4.02 8.22 -4.48
Lipid Particles 2.79 11.14 14.28 10.42 8.60 1.05 7.13 9.19 3.57 0.91 4.16 10.65 15.63 10.66 2.42
Mitochondria -4.26 5.85 2.16 4.86 -3.12 0.81 4.12 1.06 0.00 -4.59 -2.74 5.90 1.97 4.19 -6.13
Mitotic Spindle -3.87 -4.41 -12.24 -11.09 -9.43 -1.17 -1.68 -9.72 -6.39 -9.02 -2.67 -4.47 -15.51 -14.24 -13.20
None 0.78 -1.71 -7.36 -5.08 -5.03 2.09 4.57 4.67 0.10 0.18 4.88 3.80 3.04 -3.97 -2.17
Nuclear Periphery -1.06 -23.48 -15.99 -13.74 1.41 1.00 -0.87 -3.87 -14.09 -9.08 0.43 -8.17 -10.88 -16.39 -6.02
Nuclear Periphery Foci -1.78 -7.07 -5.90 -3.44 6.22 -1.01 0.29 -0.91 0.48 -2.30 0.64 -6.26 -2.44 -4.67 5.44
Nucleolus -2.22 3.59 3.10 4.41 -1.44 0.04 1.62 -0.48 -0.37 -1.36 -2.87 3.73 2.46 4.05 -1.51
Nucleus 9.48 -37.41 -33.27 -37.81 16.26 6.07 -32.63 -18.30 -19.20 9.81 9.10 -47.61 -37.92 -40.73 15.10
Peroxisomes -6.78 3.80 2.90 7.51 -1.03 -2.69 5.42 4.91 4.14 -3.23 -4.53 6.45 5.46 8.58 -2.71
Vacuole -2.56 -6.14 -11.52 -8.49 -3.43 -5.50 -12.14 -20.41 -3.41 -11.41 -6.53 -12.21 -22.06 -13.10 -9.53
Vacuole Periphery -4.75 15.06 10.98 12.19 -2.05 -0.75 4.74 -2.98 -1.82 -4.31 -5.05 9.77 -0.00 2.90 -4.24
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA
Localization
Cell Percentages cytoplasm (96%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Rit1

Rit1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rit1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available