Standard name
Human Ortholog
Description Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.85 0.96 0.72 0.4 0.48 0.52 0.51 0.44 0.46 0.45 0.39 0.32 0.75 0.76 0.66 0.86 0.78 0.84 0.69 0.69 0.66 0.64 0.72 0.67
Endoplasmic Reticulum 0 0 0.06 0.11 0.15 0.13 0.08 0.11 0.07 0.1 0.15 0.08 0.12 0.18 0.09 0 0 0 0.07 0 0.09 0.06 0.08 0.12
Endosome 0 0 0 0.15 0.19 0.15 0.11 0.08 0.08 0.07 0.06 0.05 0 0.09 0.18 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.13 0.09 0.14 0.27 0.33 0.32 0.43 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0.06 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.05 0.05 0 0 0.05
Nucleolus 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.15 0 0.23 0.38 0.25 0.11 0.24 0.27 0.19 0.14 0.16 0.18 0.1 0.05 0.08 0.15 0.26 0.12 0.05 0.12 0.09 0.09 0.06 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 3 4 5 4 9 4 7 4 5 1 0 4 0 0 0 0 0 0 0 1 0
Bud 0 0 3 2 0 6 4 9 7 8 4 10 1 0 2 0 0 0 0 1 2 0 3 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 2 1 2 0 1 4 2 3 4 4 0 0 1 2 2 0 0 0 0 0 0 0
Cytoplasm 115 108 213 96 166 124 201 191 112 151 87 118 109 155 146 106 54 102 100 97 251 48 168 152
Endoplasmic Reticulum 5 2 17 26 51 30 30 49 16 32 33 29 18 36 20 3 2 2 9 3 35 4 18 27
Endosome 0 0 1 35 67 37 42 37 20 23 13 18 5 19 41 0 2 0 0 1 7 2 4 4
Golgi 0 0 0 1 4 0 0 0 0 0 0 0 1 1 1 0 0 1 0 0 0 0 0 0
Mitochondria 0 0 2 3 2 31 34 61 65 109 71 158 1 0 2 1 0 1 0 1 2 0 0 0
Nucleus 1 0 0 1 0 0 4 4 2 1 4 3 1 0 1 1 1 5 7 8 14 4 7 2
Nuclear Periphery 0 0 0 1 3 3 5 5 3 0 5 8 1 0 0 0 0 0 17 7 20 3 8 11
Nucleolus 0 0 2 16 12 5 8 12 3 3 1 7 4 1 4 0 0 0 0 0 0 0 1 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 3 2 1 3 4 2 0 0 0 1 0 0 0 1 0 0 0 3 0 0 1
Vac/Vac Membrane 20 5 69 92 86 26 96 120 45 48 35 66 15 10 17 19 18 14 7 16 36 6 14 17
Unique Cell Count 135 113 297 240 345 239 395 439 241 334 224 367 146 203 222 123 69 121 146 140 383 75 234 226
Labelled Cell Count 141 115 309 280 399 268 432 505 281 386 261 426 158 222 239 132 80 125 146 140 383 75 234 226


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 23.0 17.3 12.2 11.6 11.1 9.1 8.6 8.2 7.8 7.6 7.4 7.2 18.9 17.3 14.7 18.1 20.9 20.2 16.2 20.3 21.8
Std Deviation (1e-4) 3.8 3.2 2.4 1.8 1.6 1.4 1.7 1.3 1.5 1.5 1.4 1.3 4.6 3.0 2.7 4.4 4.1 4.9 5.4 4.2 4.3
Intensity Change (Log2) – – – -0.07 -0.13 -0.41 -0.49 -0.58 -0.64 -0.69 -0.72 -0.77 0.64 0.51 0.27 0.57 0.78 0.73 0.41 0.74 0.84

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1.3 0 1.6 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -7.4 -6.1 -4.7 -5.5 -7.5 -6.0 -6.7 -7.5 -10.1 0.7 1.2 -1.5 3.2 1.1 2.7
Endoplasmic Reticulum 2.2 3.7 2.8 1.0 2.5 0.4 1.8 3.5 1.1 2.4 4.3 1.4 -1.4 0 -1.8
Endosome 6.6 7.8 6.8 5.6 4.9 4.7 4.3 3.8 3.5 0 5.1 7.5 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 5.9 4.7 6.3 9.2 10.5 10.1 12.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 3.8 2.4 0 0 2.0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.8 0.5 -3.7 0.3 1.2 -1.3 -2.9 -2.2 -1.7 -3.3 -5.5 -4.7 -1.8 0.5 -2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 14.416 20.9874 17.2655 16.2258 14.5325 16.8432 13.4931 18.5162 16.7336 15.2569 14.8226 17.4307 18.4004 22.1027 20.044 19.016 19.004 20.1566
Actin 0.0253 0.0002 0.0068 0.0002 0.0256 0.0038 0.0274 0.0002 0.0053 0.0437 0.0021 0.0002 0.0061 0.0001 0.0096 0.0003 0.0078 0.0002
Bud 0.0002 0 0.0002 0.0001 0.0003 0.0002 0.0002 0.0001 0.0001 0.0017 0.0002 0 0.0001 0 0.0004 0 0.0001 0
Bud Neck 0.0003 0.0002 0.0006 0.0003 0.0009 0.0018 0.0004 0.0002 0.0004 0.0006 0.0007 0.0007 0.0002 0.0001 0.0018 0.0004 0.0003 0.0005
Bud Periphery 0.0002 0 0.0002 0 0.0008 0.0002 0.0002 0 0.0001 0.0024 0.0002 0 0.0001 0 0.0004 0 0.0001 0
Bud Site 0.0004 0.0001 0.0008 0.0001 0.0005 0.0007 0.0006 0.0004 0.0003 0.0058 0.0005 0 0.0005 0 0.0058 0.0001 0.0003 0
Cell Periphery 0.0001 0 0.0001 0 0.0002 0.0002 0.0001 0.0003 0 0.0002 0 0 0.0001 0 0.0001 0 0 0
Cytoplasm 0.2772 0.4118 0.3331 0.4483 0.2269 0.1835 0.4063 0.5344 0.5221 0.5383 0.3828 0.4667 0.3314 0.4237 0.4324 0.4721 0.5627 0.3147
Cytoplasmic Foci 0.0048 0.0008 0.0123 0.0009 0.0046 0.0023 0.0102 0.015 0.0121 0.0021 0.0092 0.0016 0.0142 0.0212 0.011 0.0085 0.0092 0.0054
Eisosomes 0.0003 0 0.0001 0 0.0005 0.0001 0.0002 0 0 0.0002 0 0 0 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0222 0.01 0.0153 0.014 0.0168 0.0133 0.0459 0.0251 0.0245 0.0362 0.0297 0.021 0.0415 0.022 0.0312 0.0227 0.014 0.0256
Endosome 0.0077 0.0041 0.0139 0.0064 0.0235 0.0141 0.0297 0.0102 0.0123 0.0094 0.056 0.0044 0.0352 0.0054 0.0087 0.0255 0.0164 0.0194
Golgi 0.0032 0.0001 0.0038 0.0001 0.0204 0.0013 0.004 0.0005 0.0027 0.0079 0.0044 0 0.0066 0.0001 0.0038 0.0003 0.0058 0.0004
Lipid Particles 0.0096 0.0001 0.0081 0.0001 0.0381 0.0014 0.0111 0.0002 0.0027 0.0021 0.0042 0 0.0046 0.0002 0.0052 0.0014 0.0042 0.0006
Mitochondria 0.018 0.0002 0.003 0.0004 0.0386 0.0006 0.0018 0.0002 0.0007 0.0105 0.0035 0.0002 0.0018 0.0001 0.0011 0.0001 0.0038 0.0002
None 0.0013 0.0002 0.0008 0.0004 0.0005 0.0007 0.0067 0.0004 0.0009 0.0005 0.0023 0.0004 0.0011 0.0002 0.0005 0.0009 0.0005 0.0007
Nuclear Periphery 0.4341 0.3318 0.3803 0.3564 0.3163 0.4331 0.2965 0.2157 0.2553 0.177 0.2678 0.2721 0.3418 0.3375 0.326 0.2978 0.2109 0.3444
Nucleolus 0.0007 0.0001 0.0003 0.0001 0.0003 0.0005 0.0002 0.0003 0.0001 0.0001 0.0011 0 0.0004 0.0001 0.0001 0.0002 0.0001 0.0001
Nucleus 0.1775 0.2313 0.2052 0.1578 0.2719 0.3281 0.1467 0.1808 0.1458 0.1548 0.2113 0.2263 0.1961 0.1747 0.1487 0.1568 0.1433 0.2773
Peroxisomes 0.0007 0 0.0049 0 0.0029 0.0001 0.0017 0.0001 0.0042 0.0008 0.0022 0 0.0016 0 0.0076 0 0.0119 0.0001
Punctate Nuclear 0.0038 0.001 0.0034 0.001 0.0029 0.0022 0.0034 0.0111 0.0057 0.0015 0.0128 0.0023 0.0033 0.0096 0.0025 0.0039 0.0026 0.0043
Vacuole 0.0064 0.0046 0.0038 0.0079 0.0038 0.0074 0.0044 0.0032 0.003 0.0026 0.0047 0.0024 0.0085 0.0028 0.0016 0.0074 0.0035 0.0035
Vacuole Periphery 0.006 0.0034 0.0031 0.0055 0.0036 0.0045 0.0024 0.0014 0.0016 0.0014 0.0045 0.0017 0.0048 0.0021 0.0015 0.0015 0.0025 0.0025

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 134.6356 112.5132 95.3528 115.6379 112.874 97.1268 92.7938 85.5303 83.8122 119.1189
Translational Efficiency 0.7538 0.7897 0.8101 0.6465 0.692 0.8566 0.6993 0.5914 0.7057 0.6171

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1692 1596 447 953 1392 1739 860 533 3084 3335 1307 1486

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1125.76 1598.68 2155.12 1700.98 1251.07 1562.94 1748.13 1902.82 1182.32 1580.04 1887.32 1773.38
Standard Deviation 193.96 309.73 304.81 318.78 237.20 275.48 367.35 332.11 223.44 292.92 397.30 337.79
Intensity Change Log 2 — 0.505982 0.936869 0.595467 — 0.321100 0.482650 0.604977 — 0.411625 0.715637 0.600480

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000134 0.000097 0.000236 0.000814 0.000215 0.000261 0.000332 0.000310 0.000171 0.000182 0.000299 0.000633
Bud Neck 0.001414 0.001682 0.013120 0.007387 0.001787 0.001988 0.005961 0.007721 0.001582 0.001841 0.008409 0.007507
Bud Site 0.000850 0.001007 0.001091 0.016568 0.001401 0.001529 0.002075 0.012605 0.001099 0.001279 0.001738 0.015147
Cell Periphery 0.000052 0.000056 0.000354 0.000218 0.000069 0.000059 0.000169 0.000292 0.000059 0.000057 0.000232 0.000245
Cytoplasm 0.634875 0.546348 0.320604 0.365515 0.564192 0.501155 0.351555 0.328624 0.602971 0.522783 0.340969 0.352283
Cytoplasmic Foci 0.011660 0.006674 0.003180 0.018187 0.006327 0.011547 0.003215 0.010129 0.009253 0.009215 0.003203 0.015297
Eisosomes 0.000003 0.000002 0.000003 0.000009 0.000003 0.000003 0.000011 0.000005 0.000003 0.000002 0.000009 0.000007
Endoplasmic Reticulum 0.015192 0.016141 0.003635 0.004921 0.012295 0.020511 0.009652 0.002284 0.013885 0.018420 0.007594 0.003975
Endosome 0.003699 0.004560 0.005066 0.023936 0.003851 0.006579 0.005619 0.008196 0.003767 0.005613 0.005430 0.018290
Golgi 0.000414 0.001060 0.000807 0.007188 0.000697 0.001560 0.000610 0.001195 0.000541 0.001321 0.000678 0.005038
Lipid Particles 0.002421 0.002538 0.005371 0.011216 0.002201 0.003373 0.003840 0.019691 0.002322 0.002973 0.004364 0.014256
Mitochondria 0.000603 0.000596 0.001038 0.005003 0.000593 0.000705 0.000884 0.001579 0.000599 0.000653 0.000937 0.003775
Mitotic Spindle 0.021109 0.036647 0.097108 0.254077 0.033042 0.043805 0.062739 0.208801 0.026495 0.040380 0.074493 0.237837
None 0.008924 0.003386 0.004350 0.010687 0.006467 0.002491 0.005812 0.005070 0.007815 0.002919 0.005312 0.008672
Nuclear Periphery 0.035608 0.066847 0.106577 0.021704 0.044728 0.089479 0.102228 0.036514 0.039725 0.078648 0.103716 0.027016
Nuclear Periphery Foci 0.138679 0.230518 0.211023 0.094225 0.218473 0.221535 0.148200 0.192553 0.174695 0.225834 0.169686 0.129493
Nucleolus 0.001537 0.000492 0.000550 0.000853 0.001307 0.000733 0.001190 0.000385 0.001434 0.000618 0.000971 0.000685
Nucleus 0.103144 0.064577 0.194423 0.089621 0.085468 0.067078 0.236350 0.108901 0.095166 0.065881 0.222011 0.096537
Peroxisomes 0.000072 0.000025 0.000034 0.001158 0.000097 0.000079 0.000093 0.000278 0.000083 0.000053 0.000073 0.000842
Vacuole 0.018836 0.015823 0.030912 0.062446 0.015632 0.023807 0.058642 0.051618 0.017390 0.019986 0.049158 0.058562
Vacuole Periphery 0.000774 0.000924 0.000517 0.004268 0.001157 0.001724 0.000824 0.003247 0.000947 0.001341 0.000719 0.003902

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.60 -7.23 -3.89 -4.35 0.07 -0.40 -4.59 -1.47 -0.13 2.92 -0.26 -8.24 -3.99 -2.43 0.88
Bud Neck -1.23 -11.19 -12.08 -12.01 6.17 -1.72 -9.02 -9.39 -8.86 -1.87 -2.15 -14.08 -15.35 -14.77 2.93
Bud Site -1.24 -6.01 -7.00 -6.16 -5.23 -0.29 -2.37 -3.77 -3.77 -3.07 -1.16 -5.11 -7.61 -7.17 -5.88
Cell Periphery -2.06 -10.47 -8.77 -8.15 8.01 1.15 -9.35 -6.76 -6.98 -2.77 -0.44 -13.37 -10.37 -10.28 4.77
Cytoplasm 8.08 25.67 23.21 14.68 -5.55 5.08 18.69 15.11 11.67 -0.35 9.79 31.97 26.82 18.33 -4.03
Cytoplasmic Foci 5.32 7.20 0.80 -2.70 -3.85 -4.16 3.60 -2.74 0.04 -5.07 0.22 8.72 -1.27 -1.45 -6.66
Eisosomes 5.62 -5.66 -9.10 -13.78 -1.97 -0.62 -10.68 -6.10 -5.41 6.18 1.88 -12.00 -10.88 -12.39 4.78
Endoplasmic Reticulum -0.46 10.55 11.40 11.89 2.86 -4.89 3.82 10.27 15.78 8.96 -3.81 8.79 14.89 18.92 7.97
Endosome -2.22 -5.44 -4.45 -3.61 -1.70 -5.74 -5.07 -3.03 0.97 0.43 -6.00 -7.41 -5.19 -2.60 -1.65
Golgi -1.53 -6.06 -2.68 -1.18 -1.33 -2.05 1.03 0.12 2.14 -0.99 -2.62 -1.10 -2.52 -0.29 -1.99
Lipid Particles -1.42 -7.58 -8.02 -7.65 -0.92 -4.01 -7.17 -9.15 -8.51 -7.45 -4.06 -10.38 -12.08 -11.21 -7.07
Mitochondria 0.06 -5.48 -1.55 -1.49 -0.09 -0.60 -3.73 -0.60 -0.24 1.15 -0.32 -6.69 -1.65 -1.49 -0.13
Mitotic Spindle -4.56 -8.72 -17.60 -15.25 -7.09 -2.43 -6.97 -11.80 -10.90 -7.29 -5.09 -11.34 -20.98 -18.70 -11.00
None 5.44 3.95 -0.62 -6.39 -4.81 6.02 1.53 -0.37 -5.80 -1.80 7.79 3.83 -0.98 -8.41 -4.72
Nuclear Periphery -7.88 -8.44 6.15 13.39 11.25 -9.32 -5.85 5.16 13.50 9.24 -12.48 -10.02 8.40 19.83 14.73
Nuclear Periphery Foci -9.73 -3.13 12.75 21.71 11.08 0.35 9.64 8.02 8.46 -0.54 -6.78 4.90 15.43 22.86 8.63
Nucleolus 4.18 1.56 0.44 -5.88 -1.48 2.43 1.21 2.41 -0.02 1.54 4.69 2.13 1.37 -4.75 -1.12
Nucleus 8.91 -10.36 -4.93 -11.24 7.22 3.29 -18.16 -4.83 -6.73 10.68 8.76 -20.44 -7.22 -12.94 13.45
Peroxisomes 2.36 0.23 -2.73 -3.12 -2.78 0.42 -0.44 -1.21 -1.48 -1.07 1.35 -0.66 -2.94 -3.32 -2.80
Vacuole 1.52 -7.65 -20.06 -20.54 -12.37 -5.43 -15.76 -14.18 -12.65 -2.89 -3.00 -17.13 -24.55 -23.73 -9.93
Vacuole Periphery -0.39 1.62 -1.34 -0.73 -2.12 -1.04 1.85 0.34 1.00 -0.65 -1.21 1.91 -0.54 0.50 -1.70
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p
Localization
Cell Percentages cytoplasm (42%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-6

Pse1

Pse1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pse1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available