ORF
Human Ortholog
Description Putative methyltransferase; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; not an essential gene; YMR310C has a paralog, YGR283C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.05 0.06 0.09 0.06 0.09 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.06 0.11 0.17 0.08 0.05 0.07 0 0.08 0 0.06 0.15 0.08 0.07 0 0 0 0 0 0 0.05 0 0.05
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.22 0.25 0.5 0.31 0.5 0.5 0.46 0.6 0.46 0.43 0.38 0.4 0.4 0.34 0.36 0.24 0.16 0.21 0.14 0.1 0.14 0.11 0.17 0.12
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Endosome 0 0.2 0.06 0 0.07 0.09 0 0 0 0 0 0 0 0.2 0.26 0.22 0.27 0.23 0.12 0.12 0.1 0.14 0.12 0.15
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.76 0.14 0.06 0.11 0.05 0.12 0.42 0.27 0.52 0.51 0.68 0.53 0 0 0 0.1 0.08 0.12 0.05 0.06 0.14 0.07 0.05 0
Nucleus 0.05 0.15 0.14 0 0 0 0 0 0 0 0 0 0.17 0 0 0.14 0.2 0.18 0.09 0.15 0.05 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.16 0.07 0.07 0.1 0.08 0.07 0.09 0.06
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0.06 0.19 0.5 0.34 0.34 0.19 0.19 0.16 0.15 0.09 0.22 0.32 0.42 0.38 0.42 0.42 0.29 0.19 0.19 0.2 0.39 0.35 0.35
Vac/Vac Membrane 0.07 0.39 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0.11 0.22 0.21 0.17 0.08 0.08 0.1
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 2 0 0 2 0 1 0 0 0 0 2 0 0 1 0
Bud 1 0 1 1 3 5 18 15 24 16 20 13 1 0 0 3 1 2 1 2 1 0 4 5
Bud Neck 1 0 6 12 26 15 18 16 11 22 7 14 26 14 15 1 2 0 2 0 1 6 7 10
Bud Site 0 0 0 3 0 4 11 5 8 11 5 5 0 0 0 0 5 2 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 28 27 48 33 76 98 152 145 122 114 87 92 69 62 73 32 26 21 25 16 23 15 38 26
Endoplasmic Reticulum 0 2 0 0 0 0 0 2 0 0 0 0 2 1 2 5 6 7 0 0 2 0 1 1
Endosome 1 21 6 2 10 17 4 5 1 3 0 3 5 37 51 29 42 23 21 19 15 20 27 34
Golgi 1 1 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 1 0 2
Mitochondria 99 15 6 12 8 24 137 64 139 133 155 123 2 1 2 13 13 12 9 9 23 10 12 10
Nucleus 7 16 13 4 1 1 6 7 3 7 5 4 29 8 5 18 31 18 16 24 8 2 3 1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 2 2
Nucleolus 2 1 0 1 0 0 0 0 1 1 0 1 0 1 0 10 25 7 11 15 13 10 20 13
Peroxisomes 0 0 0 0 0 6 4 2 1 0 0 2 0 1 6 0 2 0 0 0 0 0 0 1
SpindlePole 5 6 18 54 51 66 62 46 43 39 21 50 55 76 75 55 66 28 33 30 32 56 78 80
Vac/Vac Membrane 9 42 4 2 1 1 3 5 1 4 2 2 2 3 3 9 10 11 38 33 27 12 17 23
Unique Cell Count 130 107 96 107 151 196 330 240 265 263 228 231 174 182 200 131 158 98 177 162 166 145 227 228
Labelled Cell Count 154 131 103 124 177 237 415 313 354 354 303 309 193 204 233 177 230 131 177 162 166 145 227 228


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 4.5 4.9 4.7 4.8 4.1 3.5 4.0 3.2 3.3 3.0 3.4 4.9 5.2 5.0 6.8 6.9 6.2 4.7 5.2 5.6
Std Deviation (1e-4) 0.4 0.8 1.5 1.8 1.9 2.1 1.8 1.7 1.6 1.3 1.4 1.2 1.0 1.2 1.3 1.7 2.1 1.8 1.3 1.8 2.1
Intensity Change (Log2) – – – -0.04 -0.03 -0.26 -0.48 -0.27 -0.59 -0.55 -0.68 -0.52 -0.0 0.11 0.04 0.47 0.51 0.35 -0.06 0.1 0.21

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 0.9 0.7 1.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.0065 -0.5669 -0.6229 -0.7827 -0.666 -0.6393 -0.1653 -0.3038 -0.1454 -0.348 -0.6429 -0.1746 -1.0379 -0.8433 -1.0789 -0.0163 -0.4433 -0.9918
Actin 0.0169 0.0013 0.0137 0.0105 0.0179 0.0027 0.0365 0.0002 0.0117 0.0002 0.0004 0.0074 0.0095 0.0001 0.0003 0.0432 0.0478 0.0071
Bud 0.0007 0.0084 0.0032 0.0008 0.0024 0.0037 0.0004 0.0003 0.0003 0.0007 0.0001 0.0002 0.0002 0.0002 0.0003 0.0007 0.0029 0.0003
Bud Neck 0.0131 0.005 0.0048 0.0077 0.0269 0.0071 0.0091 0.0095 0.0065 0.0085 0.0078 0.0102 0.0101 0.0075 0.0115 0.0054 0.0098 0.0137
Bud Periphery 0.0016 0.0015 0.0015 0.0012 0.0075 0.0009 0.0007 0.0004 0.0006 0.0018 0.0001 0.0005 0.0005 0.0003 0.0005 0.0016 0.0081 0.0005
Bud Site 0.0094 0.0137 0.006 0.0053 0.027 0.001 0.0034 0.0102 0.006 0.0057 0.0014 0.0016 0.0046 0.0071 0.0056 0.004 0.0094 0.0024
Cell Periphery 0.0005 0.0005 0.0005 0.0005 0.0009 0.0002 0.0004 0.0004 0.0005 0.0009 0.0001 0.0003 0.0005 0.0004 0.0006 0.0004 0.0008 0.0003
Cytoplasm 0.0182 0.0237 0.0291 0.0132 0.0104 0.014 0.0152 0.022 0.0129 0.0049 0.0135 0.0143 0.0135 0.0288 0.0185 0.0164 0.0693 0.019
Cytoplasmic Foci 0.0804 0.0279 0.0331 0.0538 0.0297 0.0376 0.0578 0.0525 0.0397 0.0297 0.1397 0.0354 0.0574 0.0494 0.0507 0.0483 0.0609 0.041
Eisosomes 0.0004 0.0001 0.0003 0.0001 0.0005 0.0001 0.0008 0.0001 0.0002 0.0002 0.0001 0.0002 0.0002 0.0001 0.0001 0.0008 0.0009 0.0002
Endoplasmic Reticulum 0.0045 0.0022 0.0024 0.0009 0.0051 0.0013 0.0024 0.0012 0.002 0.0009 0.0009 0.0012 0.0015 0.0017 0.0014 0.0022 0.0025 0.001
Endosome 0.0727 0.0232 0.037 0.0534 0.0295 0.0187 0.0302 0.0185 0.0254 0.0199 0.027 0.0168 0.0377 0.035 0.0299 0.0257 0.0242 0.0173
Golgi 0.0174 0.0033 0.0054 0.0254 0.0127 0.0047 0.007 0.0024 0.0032 0.0027 0.0034 0.0025 0.005 0.0039 0.0031 0.0091 0.0115 0.0045
Lipid Particles 0.1263 0.0482 0.0547 0.0856 0.02 0.0749 0.0605 0.0602 0.054 0.1318 0.054 0.0473 0.079 0.0807 0.0932 0.0456 0.0368 0.0754
Mitochondria 0.0092 0.0028 0.0106 0.0089 0.0409 0.0044 0.0037 0.001 0.0018 0.0022 0.0009 0.0015 0.0008 0.0005 0.0014 0.0029 0.0177 0.0013
None 0.0606 0.073 0.0983 0.0497 0.0997 0.0756 0.079 0.084 0.0719 0.0757 0.034 0.0643 0.0508 0.0379 0.0332 0.1568 0.0429 0.0394
Nuclear Periphery 0.0387 0.0196 0.013 0.005 0.0334 0.0169 0.0233 0.0116 0.0085 0.0074 0.0133 0.017 0.0172 0.0099 0.0095 0.0181 0.0176 0.0104
Nucleolus 0.1572 0.2965 0.2848 0.2802 0.1755 0.2443 0.1952 0.3195 0.4278 0.4026 0.1578 0.2316 0.2599 0.3002 0.3515 0.3001 0.1378 0.2421
Nucleus 0.1144 0.2128 0.156 0.1839 0.2705 0.1328 0.1396 0.1798 0.1556 0.0872 0.0796 0.2122 0.1192 0.1966 0.141 0.158 0.1554 0.1332
Peroxisomes 0.0361 0.0027 0.0076 0.0114 0.003 0.0071 0.0197 0.006 0.0031 0.0096 0.0111 0.0068 0.0095 0.0079 0.0095 0.0102 0.0155 0.0071
Punctate Nuclear 0.2064 0.2214 0.226 0.1863 0.1741 0.3472 0.3081 0.2128 0.1621 0.192 0.4523 0.3221 0.3148 0.2204 0.2226 0.1481 0.3174 0.3793
Vacuole 0.0095 0.0114 0.0107 0.0134 0.0085 0.0037 0.0059 0.0067 0.0057 0.014 0.0019 0.006 0.0074 0.0108 0.0143 0.0019 0.0082 0.004
Vacuole Periphery 0.0056 0.0009 0.0014 0.0026 0.0039 0.001 0.0013 0.0006 0.0006 0.0014 0.0006 0.0007 0.0007 0.0008 0.0013 0.0007 0.0027 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.0718 13.4412 19.1807 25.6141 22.4939 15.0276 16.7266 18.3452 12.3383 24.4734
Translational Efficiency 1.0108 1.9974 1.5447 0.5674 0.9752 1.3818 1.3224 0.8625 1.4226 1.0685

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
151 697 1866 1801 913 1823 158 1481 1064 2520 2024 3282

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 708.10 752.06 748.89 924.64 660.11 644.36 934.58 899.69 666.92 674.15 763.39 913.38
Standard Deviation 77.53 96.92 100.64 123.36 76.04 83.34 100.57 130.51 78.07 99.72 112.29 127.24
Intensity Change Log 2 — 0.086895 0.080801 0.384939 — -0.034840 0.501612 0.446722 — 0.029443 0.299148 0.415077

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000139 0.000787 0.000453 0.000758 0.000124 0.000209 0.001261 0.001241 0.000126 0.000369 0.000516 0.000976
Bud Neck 0.005488 0.020213 0.019085 0.031366 0.005164 0.011253 0.006972 0.030232 0.005210 0.013731 0.018139 0.030854
Bud Site 0.000822 0.007944 0.005124 0.005020 0.002555 0.003260 0.007115 0.014866 0.002309 0.004556 0.005280 0.009463
Cell Periphery 0.000192 0.000195 0.000087 0.000068 0.000149 0.000174 0.000138 0.000151 0.000155 0.000180 0.000091 0.000106
Cytoplasm 0.286468 0.120796 0.061422 0.003131 0.287191 0.207552 0.019375 0.025138 0.287089 0.183556 0.058140 0.013062
Cytoplasmic Foci 0.235698 0.106702 0.002677 0.001367 0.196872 0.117913 0.004102 0.004274 0.202383 0.114812 0.002788 0.002678
Eisosomes 0.000190 0.000149 0.000041 0.000047 0.000142 0.000133 0.000155 0.000065 0.000149 0.000137 0.000050 0.000055
Endoplasmic Reticulum 0.001391 0.004794 0.002556 0.003233 0.001264 0.001671 0.006523 0.004029 0.001282 0.002535 0.002866 0.003592
Endosome 0.010043 0.020008 0.002354 0.003122 0.011616 0.013598 0.003179 0.006833 0.011393 0.015371 0.002419 0.004797
Golgi 0.001485 0.008283 0.000372 0.001184 0.001775 0.004145 0.000766 0.004475 0.001734 0.005289 0.000403 0.002669
Lipid Particles 0.058278 0.031860 0.000978 0.000296 0.036250 0.037357 0.003190 0.000750 0.039377 0.035836 0.001151 0.000501
Mitochondria 0.008595 0.031212 0.001912 0.004023 0.007340 0.018525 0.002973 0.004937 0.007518 0.022034 0.001995 0.004435
Mitotic Spindle 0.001306 0.050434 0.016233 0.094173 0.005134 0.011435 0.013917 0.102655 0.004591 0.022222 0.016052 0.098000
None 0.009448 0.020576 0.011836 0.001716 0.014371 0.025003 0.011093 0.007298 0.013672 0.023779 0.011778 0.004235
Nuclear Periphery 0.002680 0.008669 0.001828 0.004172 0.003167 0.006227 0.001890 0.002781 0.003098 0.006903 0.001833 0.003544
Nuclear Periphery Foci 0.002880 0.016905 0.003991 0.011180 0.004430 0.009498 0.023589 0.005630 0.004210 0.011547 0.005521 0.008675
Nucleolus 0.026896 0.171195 0.189830 0.433979 0.039018 0.126035 0.284803 0.324132 0.037298 0.138526 0.197244 0.384410
Nucleus 0.316897 0.341172 0.673235 0.391466 0.364228 0.380497 0.594602 0.436769 0.357511 0.369620 0.667097 0.411909
Peroxisomes 0.015025 0.020089 0.001767 0.001461 0.006735 0.014532 0.003918 0.002010 0.007912 0.016069 0.001935 0.001709
Vacuole 0.015087 0.013195 0.003737 0.005485 0.011434 0.009587 0.010027 0.016643 0.011952 0.010585 0.004228 0.010520
Vacuole Periphery 0.000991 0.004822 0.000481 0.002754 0.001039 0.001396 0.000411 0.005092 0.001032 0.002343 0.000475 0.003809

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.80 -9.02 -16.39 -1.65 -6.43 -1.86 -7.77 -10.30 -9.73 2.40 -5.34 -11.07 -15.75 -11.80 -6.13
Bud Neck -6.69 -10.10 -17.01 -10.33 -9.80 -5.63 -2.79 -20.38 -17.24 -8.70 -8.56 -14.79 -27.82 -21.66 -13.13
Bud Site -3.96 -5.35 -8.90 0.16 -1.01 -0.48 -2.35 -8.56 -8.79 -2.07 -1.86 -3.45 -8.67 -7.66 -5.00
Cell Periphery 0.09 4.20 4.62 7.36 1.38 -1.49 -0.78 1.97 3.18 1.67 -1.64 7.23 6.61 8.66 -0.88
Cytoplasm 7.54 10.92 13.34 15.53 15.86 8.37 28.44 29.53 27.58 -1.89 11.90 28.47 34.52 33.82 11.49
Cytoplasmic Foci 6.75 12.83 12.94 18.55 4.40 10.14 29.94 30.64 30.98 1.76 12.51 33.27 33.45 36.39 2.42
Eisosomes 1.58 6.12 6.28 17.02 1.37 1.70 -2.88 14.45 14.72 6.84 1.99 15.90 17.88 23.94 1.45
Endoplasmic Reticulum -5.13 -3.21 -4.29 1.91 -2.39 -2.62 -9.63 -14.32 -13.02 4.94 -7.00 -12.94 -16.04 -9.86 -2.83
Endosome -4.14 5.53 5.20 10.26 -0.57 -0.71 3.54 5.17 8.69 0.89 -2.16 8.23 7.10 14.31 -2.81
Golgi -5.89 3.27 1.11 6.44 -3.99 -2.63 1.41 -1.19 1.07 -2.17 -5.00 4.05 -0.07 4.98 -4.27
Lipid Particles 2.64 5.80 5.87 11.96 6.12 -0.63 13.82 15.75 21.94 5.68 1.16 15.95 16.27 25.05 6.45
Mitochondria -4.90 2.16 1.40 8.53 -5.55 -4.87 2.68 2.22 8.01 -1.34 -7.01 4.34 2.57 11.38 -6.76
Mitotic Spindle -8.66 -7.62 -19.47 -8.37 -15.82 -2.83 -2.69 -18.25 -17.51 -9.95 -7.44 -6.95 -25.77 -21.24 -21.17
None -4.16 -1.37 5.12 8.94 17.15 -4.93 1.65 5.35 12.08 1.60 -5.39 2.12 7.85 16.47 12.04
Nuclear Periphery -1.87 1.30 -0.60 1.94 -7.52 -4.20 1.76 0.50 4.50 -1.22 -4.71 2.82 -1.66 3.95 -6.52
Nuclear Periphery Foci -7.41 -2.68 -7.17 2.97 -5.02 -3.61 -4.24 -0.85 3.09 4.08 -6.50 -2.29 -4.66 2.55 -2.15
Nucleolus -14.73 -23.05 -41.09 -18.39 -18.01 -14.52 -11.09 -29.03 -16.47 -0.25 -19.08 -26.59 -48.95 -28.58 -14.40
Nucleus -0.27 -13.28 -2.39 -3.78 25.81 -0.50 -6.86 -4.52 -4.67 4.86 -0.09 -24.32 -3.99 -4.98 26.42
Peroxisomes -1.01 3.95 4.02 11.84 0.29 -5.91 2.09 6.63 12.70 3.10 -6.41 7.13 8.03 17.12 0.31
Vacuole 1.43 4.84 3.73 3.78 -2.26 2.42 -2.18 -6.14 -7.02 -1.30 2.32 6.47 -3.02 -4.59 -7.31
Vacuole Periphery -4.67 2.38 -2.99 2.39 -4.57 -0.98 1.70 -3.68 -3.34 -4.64 -3.77 2.65 -4.50 -1.61 -6.65
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative methyltransferase; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; not an essential gene; YMR310C has a paralog, YGR283C, that arose from the whole genome duplication
Localization
Cell Percentages nucleus (39%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

YMR310C

YMR310C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ymr310c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available