Standard name
Human Ortholog
Description Regulatory subunit of protein phosphatase 1 (Glc7p); involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.95 0.98 0.97 0.94 0.85 0.79 0.72 – 0.66 0.62 0.61 0.61 0.98 0.96 0.97 0.85 0.84 0.92 0.85 0.84 0.86 0.91 0.86 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0.1 0.06 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0.06 – 0 0.06 0.06 0.05 0 0 0 0 0 0 0.09 0.1 0.06 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0 0 0.12 0.2 0.2 0.24 – 0.28 0.25 0.23 0.28 0 0.06 0.06 0.13 0.17 0.1 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 – 1 1 0 5 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 0 0 0 0 0 0 – 1 2 2 2 0 0 0 0 0 0 1 0 0 0 2 5
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 1 0 0 1 0 4 – 4 7 4 6 1 0 3 4 1 1 0 0 0 0 0 0
Cytoplasm 230 175 90 161 218 129 291 – 175 204 145 190 196 297 393 197 130 123 204 148 108 152 275 311
Endoplasmic Reticulum 0 1 1 1 3 0 8 – 3 16 5 12 1 0 3 11 2 3 0 0 0 0 2 8
Endosome 1 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 1 0 2 2
Golgi 2 0 1 0 0 1 1 – 0 0 2 1 0 2 0 3 0 1 2 0 0 0 3 2
Mitochondria 1 0 0 0 0 6 3 – 10 12 23 19 0 0 0 11 4 2 0 0 1 0 1 0
Nucleus 8 3 0 4 10 3 25 – 11 18 13 16 2 1 4 3 3 2 22 17 7 5 8 8
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 0 2 0 1 4
Nucleolus 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 17 2 3 21 52 32 96 – 75 83 55 87 6 20 24 29 26 13 4 7 2 4 12 8
Unique Cell Count 241 178 93 172 257 163 402 267 327 236 312 200 309 406 231 155 134 240 176 126 167 319 360
Labelled Cell Count 261 182 95 187 284 171 429 280 344 249 339 206 320 427 258 166 145 240 176 126 167 319 360


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 16.8 16.1 13.0 13.9 15.8 10.2 13.6 – 11.9 12.3 11.3 12.0 18.9 17.0 20.4 22.6 24.1 22.8 15.4 16.4 16.7
Std Deviation (1e-4) 2.8 2.6 2.5 2.0 2.4 2.4 2.3 – 2.5 2.5 2.4 2.7 3.2 2.9 3.5 7.8 9.1 7.5 2.9 3.0 3.4
Intensity Change (Log2) – – – 0.1 0.28 -0.34 0.07 – -0.13 -0.08 -0.2 -0.12 0.54 0.39 0.65 0.8 0.89 0.81 0.25 0.34 0.37


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.1 -3.0 -3.9 -5.0 – -5.9 -6.4 -6.4 -6.6 0.6 -0.3 0 -2.9 -3.1 -1.5
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 3.1 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 2.4 3.9 3.7 4.5 – 5.0 4.7 4.3 5.0 0 1.2 1.0 2.5 3.2 1.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.0942 13.0767 11.944 10.9846 10.594 11.9254 13.5035 15.957 14.9067 12.756 10.9713 14.2491 16.4997 18.1255 16.7658 16.5169 16.6524 16.2864
Actin 0.0049 0.0001 0.0002 0.0002 0.0001 0.0006 0.0102 0.0074 0.0045 0.0018 0.0068 0.0023 0.0102 0.0001 0.0002 0.0001 0.0002 0.0019
Bud 0.0001 0.0001 0.0001 0.0001 0.0001 0.0005 0.0009 0.005 0.0053 0.0003 0.0005 0.0004 0.0002 0.0001 0.0001 0 0.0001 0.0001
Bud Neck 0.0006 0.0002 0.0003 0.0004 0.0005 0.0009 0.0018 0.0007 0.0007 0.001 0.0012 0.0014 0.0004 0.0002 0.0004 0.0004 0.0007 0.0011
Bud Periphery 0.0001 0 0 0 0 0.0005 0.001 0.001 0.0011 0.0002 0.0004 0.0001 0.0002 0 0 0 0 0.0001
Bud Site 0.0005 0.0001 0.0001 0 0 0.0001 0.0068 0.0017 0.0047 0.0004 0.0013 0.0002 0.0005 0.0001 0.0002 0 0 0.0002
Cell Periphery 0.0001 0 0 0 0 0 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0 0 0 0
Cytoplasm 0.6828 0.7455 0.7175 0.6132 0.6756 0.5905 0.589 0.7824 0.7108 0.6939 0.5196 0.6469 0.6977 0.7683 0.8215 0.6947 0.779 0.6207
Cytoplasmic Foci 0.0045 0.0002 0.0008 0.0003 0.0005 0.0005 0.0095 0.0009 0.0043 0.0056 0.0788 0.0093 0.0024 0.0003 0.0006 0.0004 0.0005 0.0038
Eisosomes 0 0 0 0 0 0 0.0001 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0027 0.0012 0.0009 0.0004 0.0011 0.0028 0.0036 0.0012 0.0033 0.0101 0.0019 0.0011 0.0059 0.0005 0.0014 0.0006 0.0009 0.0019
Endosome 0.0089 0.0002 0.0005 0.0002 0.0005 0.0012 0.0352 0.0004 0.0067 0.0237 0.0832 0.0106 0.005 0.0001 0.0013 0.0001 0.0003 0.0035
Golgi 0.0019 0 0 0 0 0.0001 0.0067 0.0002 0.0021 0.0016 0.05 0.0094 0.0005 0 0 0 0 0.001
Lipid Particles 0.0061 0 0 0 0 0 0.0097 0 0.0014 0.0019 0.0234 0.0005 0.0014 0 0 0 0 0.0043
Mitochondria 0.0009 0.0001 0.0002 0.0002 0.0002 0.0023 0.0047 0.0007 0.0014 0.0007 0.0087 0.0056 0.0017 0.0001 0.0002 0.0001 0.0002 0.0017
None 0.0014 0.0003 0.0004 0.0003 0.0004 0.0003 0.0039 0.0005 0.0017 0.0013 0.0005 0.0011 0.0019 0.0003 0.0005 0.0003 0.0005 0.0011
Nuclear Periphery 0.0293 0.0135 0.0211 0.0149 0.0212 0.0266 0.025 0.0102 0.016 0.0205 0.0143 0.0151 0.0185 0.0086 0.0075 0.0072 0.0125 0.0173
Nucleolus 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001 0.0006 0.0007 0.0003 0.0002 0.0002 0.0002 0.0012 0 0.0001 0 0.0001 0.0002
Nucleus 0.2487 0.2372 0.256 0.3681 0.2956 0.3699 0.2716 0.1842 0.2298 0.2281 0.1567 0.2842 0.2465 0.2202 0.1633 0.2951 0.2035 0.3354
Peroxisomes 0.0017 0 0 0 0 0 0.0018 0.0002 0.0006 0.0003 0.0462 0.0008 0.0006 0 0 0 0 0.0023
Punctate Nuclear 0.0029 0.0009 0.0011 0.0012 0.0025 0.001 0.0072 0.0018 0.0028 0.0052 0.0032 0.0095 0.0035 0.0007 0.001 0.0007 0.001 0.0026
Vacuole 0.0012 0.0003 0.0006 0.0003 0.0012 0.0015 0.0077 0.0006 0.0017 0.0023 0.0022 0.0009 0.0012 0.0002 0.0013 0.0001 0.0004 0.0006
Vacuole Periphery 0.0005 0.0001 0.0002 0.0001 0.0003 0.0006 0.0027 0.0002 0.0006 0.0007 0.0008 0.0003 0.0004 0 0.0002 0 0.0001 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.9827 30.0201 28.6409 38.5031 43.5404 54.3406 39.7484 43.4118 55.7603 44.9746
Translational Efficiency 4.2204 4.2083 3.3818 3.3379 3.1344 2.9136 2.6294 2.9782 2.3516 2.7598

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2636 1219 613 1625 1685 1913 295 1586 4321 3132 908 3211

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1306.22 1274.93 2141.28 1890.35 1257.13 1433.51 1886.48 1917.38 1287.08 1371.79 2058.50 1903.70
Standard Deviation 190.20 234.33 295.77 361.61 199.59 228.70 288.43 344.88 195.39 243.51 316.74 353.71
Intensity Change Log 2 — -0.034980 0.713076 0.533255 — 0.189418 0.585563 0.609002 — 0.079432 0.651947 0.570901

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000165 0.001184 0.000193 0.001609 0.000255 0.000131 0.000536 0.002427 0.000200 0.000541 0.000304 0.002013
Bud Neck 0.001445 0.000916 0.001895 0.004088 0.001326 0.001847 0.003047 0.004411 0.001399 0.001485 0.002269 0.004248
Bud Site 0.001362 0.002419 0.002751 0.014225 0.002458 0.003846 0.001467 0.009693 0.001790 0.003291 0.002334 0.011986
Cell Periphery 0.000048 0.000095 0.000158 0.000147 0.000085 0.000040 0.000251 0.000133 0.000062 0.000062 0.000188 0.000140
Cytoplasm 0.576412* 0.551519* 0.155280* 0.355091* 0.551122* 0.573612* 0.181576* 0.359605* 0.566550* 0.565013* 0.163823* 0.357320*
Cytoplasmic Foci 0.006830 0.004131 0.001651 0.006552 0.006733 0.003874 0.001510 0.005849 0.006792 0.003974 0.001606 0.006205
Eisosomes 0.000004 0.000004 0.000003 0.000007 0.000006 0.000003 0.000008 0.000009 0.000005 0.000003 0.000004 0.000008
Endoplasmic Reticulum 0.001082 0.000603 0.000206 0.000793 0.001420 0.000438 0.000851 0.000857 0.001214 0.000502 0.000416 0.000825
Endosome 0.000362 0.000679 0.000146 0.003458 0.000727 0.000443 0.000254 0.004038 0.000504 0.000535 0.000181 0.003744
Golgi 0.000359 0.000831 0.000203 0.003228 0.000623 0.000118 0.000139 0.007785 0.000462 0.000395 0.000182 0.005479
Lipid Particles 0.000255 0.000253 0.000225 0.001563 0.000418 0.000134 0.000573 0.000690 0.000319 0.000180 0.000338 0.001132
Mitochondria 0.000683 0.000765 0.000667 0.000580 0.001322 0.000380 0.000679 0.000742 0.000932 0.000530 0.000671 0.000660
Mitotic Spindle 0.005095 0.002051 0.001739 0.031099 0.003869 0.003439 0.001151 0.047775 0.004617 0.002899 0.001548 0.039336
None 0.004868 0.013084 0.007443 0.015217 0.006381 0.010723 0.009976 0.017291 0.005458 0.011642 0.008266 0.016241
Nuclear Periphery 0.000415 0.000211 0.000552 0.000645 0.000418 0.000277 0.000803 0.000788 0.000417 0.000251 0.000634 0.000716
Nuclear Periphery Foci 0.001376 0.001840 0.000219 0.001655 0.003039 0.000671 0.000898 0.004151 0.002024 0.001126 0.000440 0.002888
Nucleolus 0.000264 0.000208 0.000103 0.000460 0.000244 0.000140 0.000188 0.000262 0.000256 0.000166 0.000131 0.000362
Nucleus 0.387527* 0.409838* 0.821735* 0.548694* 0.406141* 0.391835* 0.778017* 0.519486* 0.394786* 0.398842* 0.807531* 0.534268*
Peroxisomes 0.000190 0.000228 0.000053 0.000332 0.000178 0.000124 0.000039 0.000633 0.000185 0.000165 0.000048 0.000480
Vacuole 0.010999 0.008479 0.004729 0.010051 0.012743 0.007782 0.017980 0.011126 0.011679 0.008053 0.009034 0.010582
Vacuole Periphery 0.000257 0.000661 0.000051 0.000505 0.000490 0.000143 0.000058 0.002249 0.000348 0.000344 0.000053 0.001366

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.95 -2.81 -2.63 1.13 -0.64 4.41 -8.02 -2.61 -3.34 1.31 -1.67 -5.52 -3.78 -0.38 -0.16
Bud Neck 0.74 -5.45 -6.50 -7.80 -1.78 -1.22 -8.87 -7.48 -5.82 1.90 -0.51 -9.81 -9.62 -8.74 -0.53
Bud Site -2.02 -0.96 -5.32 -3.70 -3.57 -1.04 -2.36 -3.96 -2.56 -2.60 -2.22 -1.56 -6.81 -4.16 -4.40
Cell Periphery -3.16 -9.81 -13.78 -5.19 3.73 8.49 -9.40 -8.94 -13.32 6.65 -0.35 -13.30 -16.61 -13.08 6.99
Cytoplasm 4.56 67.50* 40.22 26.73 -27.32 -1.40 38.94 28.27 31.43 -18.24 2.39 76.94 48.97 42.11 -33.75
Cytoplasmic Foci 2.64 8.36 1.87 -0.80 -4.28 3.83 6.06 2.90 -0.96 -2.99 4.80 10.35 3.34 -1.34 -5.44
Eisosomes -0.72 -3.50 -7.00 -4.55 -1.90 4.94 -7.77 -3.12 -7.95 6.11 2.92 -7.64 -7.32 -9.41 2.72
Endoplasmic Reticulum 4.10 8.37 6.06 2.64 -0.03 9.64 1.68 8.34 0.51 6.48 10.00 7.90 9.88 2.14 3.52
Endosome -1.35 1.42 -1.32 -0.23 -1.74 2.04 1.57 -0.60 -1.96 -1.60 0.01 2.32 -1.62 -1.48 -2.60
Golgi -1.05 0.95 -0.83 0.18 -1.21 1.75 1.13 -1.43 -2.40 -2.11 0.48 1.49 -1.76 -1.99 -2.45
Lipid Particles -1.52 -2.49 -6.37 -5.61 -2.63 3.54 -6.41 -7.47 -13.10 1.71 2.01 -4.69 -9.53 -10.55 -1.95
Mitochondria -0.10 -1.19 -0.20 -0.04 5.55 1.58 0.44 0.88 -3.56 3.91 1.28 -0.37 0.55 -1.65 6.51
Mitotic Spindle 2.02 -0.01 -6.16 -7.37 -5.09 0.00 1.31 -7.71 -7.69 -8.45 1.28 0.23 -9.74 -10.47 -8.51
None -9.68 -3.75 -16.69 -2.93 -11.91 -5.84 -2.41 -14.78 -8.51 -7.67 -11.53 -4.12 -22.80 -8.39 -14.94
Nuclear Periphery 6.73 -10.73 -11.41 -14.24 -0.10 3.21 -11.44 -13.90 -17.19 2.53 6.73 -15.32 -18.18 -22.09 0.73
Nuclear Periphery Foci -2.73 5.38 0.35 2.72 -3.55 7.41 3.09 2.72 -2.72 0.08 3.55 6.06 2.03 -0.77 -2.46
Nucleolus 0.54 1.41 -0.85 -1.66 -3.23 0.78 -0.44 -2.26 -2.69 -2.23 1.04 1.24 -2.15 -3.30 -3.63
Nucleus -3.72 -55.47 -21.79 -14.56 30.56 0.28 -25.25 -13.46 -14.37 16.10 -2.55 -57.72 -25.19 -21.03 34.88
Peroxisomes -0.23 1.20 0.43 0.73 -2.52 0.74 1.67 0.15 -0.52 -1.38 0.21 1.71 0.40 0.24 -2.46
Vacuole -0.38 -2.73 -15.94 -14.76 -10.92 2.94 -7.65 -14.41 -15.89 0.25 1.77 -7.39 -21.58 -21.99 -7.93
Vacuole Periphery -0.98 1.46 0.78 1.35 -0.79 1.55 1.68 -0.00 -1.25 -1.35 0.17 2.25 0.18 0.02 -1.56
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Regulatory subunit of protein phosphatase 1 (Glc7p); involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Glc8

Glc8


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Glc8-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available