Standard name
Human Ortholog
Description Sugar alcohol phosphatase; polyol phosphatase that hydrolyzes sorbitol-6-phosphate, ribitol-5-phosphate, and (D)-glycerol-3-phosphate, maintaining phosphoglucose isomerase (PGI) activity in the presence of PGI-inhibitory sugar alcohols; expression correlated with growth rate; GFP-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant displays increased glycogen accumulation; member of the haloacid dehalogenase (HAD) superfamily
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.99 0.98 0.98 0.91 0.92 0.89 – 0.83 0.81 0.78 0.72 0.99 0.99 0.99 0.99 0.99 0.98 0.93 0.95 0.97 0.96 0.96 0.95
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0.08 0.06 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.07 0.06 0.08 – 0 0.1 0.09 0.15 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 1 – 2 0 2 3 0 0 0 0 0 0 3 0 0 0 0 0
Bud 0 1 0 0 0 1 0 – 0 0 0 1 0 0 0 0 0 0 2 3 0 0 4 2
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 8 0 1 4 0 7 – 9 9 2 10 5 7 7 5 5 8 0 0 0 0 0 0
Cytoplasm 460 662 196 126 208 193 165 – 221 223 145 124 376 636 634 220 226 260 439 650 193 212 511 381
Endoplasmic Reticulum 3 1 1 0 6 3 4 – 22 16 11 10 0 4 5 1 3 7 5 2 0 1 8 4
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 1 2 0 0 – 1 6 2 5 0 2 1 0 0 0 0 0 0 1 0 0
Mitochondria 0 2 0 0 0 3 1 – 6 2 8 6 1 0 0 0 0 0 1 2 0 0 0 0
Nucleus 1 2 1 1 1 1 2 – 6 6 3 0 1 0 2 2 0 2 3 8 0 1 1 2
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 1 0 0 0 1 1
Nucleolus 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0
Vac/Vac Membrane 7 4 3 1 17 12 15 – 12 27 17 25 0 0 0 1 1 0 3 8 0 1 3 4
Unique Cell Count 470 668 199 128 229 210 186 267 275 187 172 378 642 639 223 228 264 472 685 200 221 535 403
Labelled Cell Count 471 680 201 130 238 214 195 279 289 191 185 383 649 649 229 235 277 472 685 200 221 535 403


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 26.6 23.9 22.3 22.6 23.6 15.3 19.6 – 17.6 17.9 16.1 17.4 28.0 27.4 26.6 33.3 35.8 35.2 23.7 24.1 24.2
Std Deviation (1e-4) 6.2 5.1 4.1 4.2 5.6 3.9 3.6 – 3.7 3.2 3.5 3.2 5.4 4.8 4.7 8.3 8.8 8.3 5.8 5.0 5.4
Intensity Change (Log2) – – – 0.02 0.08 -0.54 -0.18 – -0.34 -0.31 -0.47 -0.36 0.33 0.3 0.25 0.58 0.68 0.66 0.09 0.11 0.12

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 -3.4 -3.1 -4.0 – -5.5 -5.8 -6.4 -7.4 1.2 0.7 0.9 0.1 0.6 0
Endoplasmic Reticulum 0 0 0 0 – 3.8 3.1 3.0 3.0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 2.9 2.3 3.0 – 1.8 3.7 3.4 4.7 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 13.8511 18.9283 17.6853 14.3537 14.99 17.8759 22.8567 27.0974 24.0994 23.1924 22.8144 25.0841 23.5421 28.7558 25.9465 25.9949 22.6045 25.5716
Actin 0.0116 0.0001 0.0026 0.0065 0.0008 0.0001 0.0039 0.0006 0.0039 0.0021 0.0044 0.0023 0.0011 0.0001 0.0002 0.0001 0.0003 0.0003
Bud 0.0009 0 0.0002 0.0009 0.0001 0.0001 0.0061 0.0002 0.0008 0.0002 0.0002 0.0005 0.0002 0 0 0 0.0001 0
Bud Neck 0.0017 0.0001 0.0004 0.0008 0.0004 0.0006 0.0014 0.0001 0.0013 0.0007 0.0012 0.001 0.0004 0.0002 0.0002 0.0003 0.0008 0.0006
Bud Periphery 0.0008 0 0.0001 0.0005 0.0001 0 0.0027 0 0.0007 0.0004 0.0001 0.0005 0.0001 0 0 0 0 0
Bud Site 0.0031 0.0001 0.0009 0.0036 0.0003 0 0.0018 0.0001 0.002 0.0001 0.0003 0.0003 0.0002 0 0 0 0.0002 0
Cell Periphery 0.0004 0 0 0.0001 0.0001 0 0.0021 0 0.0002 0.0003 0.0003 0.0001 0 0 0 0 0.0001 0
Cytoplasm 0.8227 0.9878 0.9492 0.8366 0.9104 0.9734 0.8928 0.9877 0.9055 0.9633 0.9008 0.9633 0.9592 0.9918 0.9823 0.9912 0.9637 0.9793
Cytoplasmic Foci 0.0256 0.0003 0.0066 0.0459 0.0044 0.0006 0.0087 0.0007 0.0161 0.0006 0.01 0.0017 0.0028 0.0003 0.0036 0.0002 0.0037 0.0008
Eisosomes 0.0003 0 0 0.0001 0.0001 0 0 0 0.0001 0.0001 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0097 0.0003 0.0009 0.003 0.0057 0.0008 0.0039 0.0004 0.0024 0.005 0.0092 0.001 0.0028 0.0005 0.0005 0.0003 0.0019 0.0011
Endosome 0.0328 0.0001 0.0097 0.0426 0.0161 0.0006 0.0108 0.0001 0.0162 0.0008 0.0245 0.003 0.0026 0.0001 0.001 0.0001 0.0026 0.0003
Golgi 0.0076 0 0.0014 0.0108 0.0009 0 0.0036 0 0.0029 0.0004 0.0067 0.0005 0.0007 0 0.0002 0 0.0002 0
Lipid Particles 0.0137 0 0.0027 0.0136 0.0024 0 0.0068 0 0.0046 0.0001 0.0021 0.0001 0.0036 0 0.0013 0 0.0005 0
Mitochondria 0.0065 0 0.0067 0.0075 0.0011 0.0002 0.0048 0 0.0044 0.0066 0.0016 0.0014 0.0005 0 0.0001 0 0.0002 0
None 0.0055 0.0002 0.0006 0.0027 0.0064 0.0003 0.0019 0.0004 0.0025 0.0006 0.001 0.0005 0.0017 0.0002 0.0003 0.0002 0.0026 0.0008
Nuclear Periphery 0.0146 0.0011 0.0013 0.0031 0.0096 0.0029 0.0054 0.0008 0.0051 0.0021 0.0082 0.0016 0.0026 0.0006 0.0009 0.0006 0.0022 0.002
Nucleolus 0.0004 0 0.0001 0.0003 0.0094 0 0.0003 0 0.0009 0 0.0001 0.0001 0.0001 0 0 0 0.0011 0
Nucleus 0.0243 0.0094 0.0088 0.0098 0.0183 0.0197 0.0338 0.0082 0.0221 0.0156 0.0203 0.0197 0.0166 0.0059 0.0082 0.0067 0.0127 0.014
Peroxisomes 0.0048 0 0.0049 0.0035 0.0002 0 0.0017 0 0.0022 0 0.0008 0.0003 0.0032 0 0.0007 0 0.0001 0
Punctate Nuclear 0.0049 0.0001 0.0003 0.0054 0.0101 0.0002 0.0018 0.0002 0.002 0.0004 0.0035 0.0004 0.0009 0.0001 0.0002 0.0001 0.0055 0.0004
Vacuole 0.0061 0.0001 0.0017 0.0017 0.0024 0.0005 0.0049 0.0001 0.0034 0.0005 0.0041 0.0014 0.0006 0.0001 0.0001 0.0001 0.0013 0.0002
Vacuole Periphery 0.002 0 0.0006 0.001 0.0009 0.0001 0.0008 0 0.0007 0.0001 0.0006 0.0004 0.0001 0 0 0 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 284.9702 298.9019 288.3375 236.4947 209.8625 247.5969 282.9872 236.8923 244.8918 213.7221
Translational Efficiency 1.4375 1.4521 1.4131 1.8039 1.8202 1.6417 1.69 1.9726 1.7502 1.8061

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1823 1498 116 1268 2089 2602 2621 1791 3912 4100 2737 3059

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1666.44 2095.95 2574.33 2541.03 1693.92 2037.66 2597.74 2660.33 1681.11 2058.96 2596.75 2610.88
Standard Deviation 277.02 355.05 411.49 508.67 288.63 365.14 424.90 508.25 283.61 362.57 424.37 511.81
Intensity Change Log 2 — 0.330835 0.627428 0.608644 — 0.266548 0.616891 0.651239 — 0.298786 0.622126 0.630273

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000058 0.000127 0.000805 0.000394 0.000099 0.000094 0.000039 0.000204 0.000080 0.000106 0.000072 0.000283
Bud Neck 0.000297 0.000437 0.005564 0.002940 0.000311 0.000479 0.000299 0.000829 0.000304 0.000463 0.000522 0.001704
Bud Site 0.001092 0.001254 0.005137 0.011361 0.001048 0.001925 0.000638 0.003641 0.001069 0.001679 0.000828 0.006841
Cell Periphery 0.000044 0.000120 0.001310 0.000438 0.000057 0.000044 0.000061 0.000108 0.000051 0.000072 0.000114 0.000245
Cytoplasm 0.878061 0.797794 0.510961 0.732462 0.846336 0.836635 0.805063 0.797551 0.861120 0.822444 0.792598 0.770571
Cytoplasmic Foci 0.005753 0.005024 0.024132 0.009567 0.006157 0.004595 0.001742 0.004283 0.005969 0.004752 0.002691 0.006473
Eisosomes 0.000001 0.000001 0.000008 0.000004 0.000001 0.000001 0.000001 0.000001 0.000001 0.000001 0.000001 0.000002
Endoplasmic Reticulum 0.000107 0.000103 0.000645 0.000172 0.000200 0.000093 0.000010 0.000046 0.000157 0.000096 0.000037 0.000098
Endosome 0.000081 0.000366 0.003312 0.003307 0.000251 0.000529 0.000139 0.000875 0.000172 0.000469 0.000273 0.001883
Golgi 0.000309 0.000719 0.001247 0.004405 0.000407 0.000522 0.000449 0.001311 0.000362 0.000594 0.000483 0.002593
Lipid Particles 0.000218 0.000248 0.005359 0.001332 0.000266 0.000262 0.000109 0.000318 0.000244 0.000257 0.000332 0.000738
Mitochondria 0.000092 0.000478 0.000343 0.000857 0.000129 0.000095 0.000071 0.000110 0.000112 0.000235 0.000083 0.000420
Mitotic Spindle 0.000817 0.001553 0.003440 0.020945 0.001693 0.003134 0.000321 0.012808 0.001285 0.002556 0.000454 0.016181
None 0.009864 0.018663 0.004820 0.010712 0.009436 0.020169 0.011525 0.011760 0.009636 0.019619 0.011240 0.011326
Nuclear Periphery 0.000038 0.000062 0.001439 0.000725 0.000110 0.000039 0.000043 0.000113 0.000077 0.000047 0.000103 0.000367
Nuclear Periphery Foci 0.000952 0.002034 0.012665 0.002652 0.002696 0.001084 0.000279 0.001142 0.001883 0.001431 0.000804 0.001768
Nucleolus 0.000082 0.000081 0.000196 0.000269 0.000075 0.000096 0.000077 0.000158 0.000078 0.000091 0.000082 0.000204
Nucleus 0.097781 0.166039 0.356621 0.170839 0.123792 0.126786 0.173199 0.152534 0.111671 0.141128 0.180973 0.160122
Peroxisomes 0.000029 0.000014 0.000075 0.000175 0.000018 0.000187 0.000016 0.000099 0.000023 0.000124 0.000019 0.000131
Vacuole 0.004185 0.003999 0.061660 0.022695 0.006072 0.003051 0.005884 0.010450 0.005193 0.003397 0.008248 0.015526
Vacuole Periphery 0.000139 0.000885 0.000261 0.003748 0.000843 0.000182 0.000035 0.001659 0.000515 0.000439 0.000045 0.002525

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.56 -6.95 -6.52 -4.63 4.34 0.25 3.50 -1.81 -1.76 -3.02 -2.02 -2.61 -6.17 -4.64 -5.04
Bud Neck -4.06 -9.30 -7.73 -6.27 6.60 -1.08 -4.26 -11.10 -6.87 -7.35 -2.76 -8.43 -11.80 -8.99 -6.02
Bud Site -1.63 -7.26 -8.30 -7.74 1.81 -2.59 0.02 -5.75 -3.53 -5.83 -3.08 -2.69 -10.05 -7.96 -8.90
Cell Periphery -7.39 -8.01 -7.30 -5.49 6.00 3.67 -3.89 -9.61 -11.02 -6.15 -4.77 -8.27 -9.94 -8.75 -4.54
Cytoplasm 18.91 21.92 28.91 13.57 -13.01 1.84 14.52 17.79 16.71 6.18 13.78 24.23 32.78 21.83 8.12
Cytoplasmic Foci -0.99 -7.52 -8.45 -7.29 5.90 3.60 7.95 -2.80 -6.11 -10.09 2.23 3.08 -8.19 -9.64 -10.03
Eisosomes -1.09 -9.07 -6.65 -6.39 6.20 3.90 2.62 -6.63 -10.31 -8.67 2.32 -3.63 -8.38 -9.01 -6.05
Endoplasmic Reticulum 0.04 -3.45 1.77 1.40 3.68 3.77 7.78 6.90 2.71 -3.83 3.32 7.96 7.05 2.87 -1.55
Endosome -2.25 -2.65 -2.87 -1.70 1.65 -1.48 2.64 -0.44 0.80 -1.67 -2.49 0.01 -2.65 -0.63 -2.41
Golgi -2.09 -6.28 -2.31 -1.12 0.92 -0.61 0.56 -0.34 0.06 -0.69 -1.83 0.11 -1.97 -0.85 -1.57
Lipid Particles -2.34 -5.62 -8.72 -7.79 3.58 0.32 -0.80 -8.29 -7.11 -7.36 -1.08 -4.81 -11.47 -10.27 -7.47
Mitochondria -1.00 -4.86 -1.66 0.49 1.61 0.68 1.07 0.61 -0.40 -3.48 -0.85 0.70 -1.12 0.41 -1.71
Mitotic Spindle -1.14 -3.69 -4.20 -3.72 -2.11 -1.61 2.70 -2.76 -1.58 -3.85 -2.14 1.98 -4.98 -3.59 -5.63
None -7.00 8.83 4.92 10.17 -4.86 -9.97 -1.53 0.77 11.09 2.85 -12.15 -0.60 3.62 14.98 4.57
Nuclear Periphery -5.43 -6.19 -3.81 -3.36 4.60 3.83 1.80 -4.06 -16.00 -11.90 2.19 -4.23 -5.00 -5.76 -3.16
Nuclear Periphery Foci -3.53 -3.12 -4.79 -0.01 2.63 5.30 9.07 4.89 -1.39 -6.49 1.84 5.53 0.88 -1.17 -4.96
Nucleolus -1.02 -6.94 -3.08 -2.84 2.40 -1.61 -1.97 -2.42 -1.57 -1.73 -1.81 -3.01 -3.74 -2.84 -2.45
Nucleus -17.29 -11.83 -15.78 -0.73 7.85 -0.98 -16.14 -10.52 -10.08 3.60 -12.19 -23.88 -18.64 -8.40 5.23
Peroxisomes 3.99 -7.04 -2.66 -3.48 2.77 -1.52 0.65 -2.42 1.17 -2.58 -1.43 0.54 -3.52 0.82 -3.58
Vacuole -2.07 -7.70 -20.93 -20.22 3.77 5.55 -6.37 -16.12 -18.24 -13.60 2.95 -10.98 -26.18 -27.01 -17.20
Vacuole Periphery -1.53 -3.56 -1.71 -0.12 -1.32 1.65 2.03 0.56 -1.00 -1.42 0.33 2.21 -0.53 -0.83 -2.32
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Sugar alcohol phosphatase; polyol phosphatase that hydrolyzes sorbitol-6-phosphate, ribitol-5-phosphate, and (D)-glycerol-3-phosphate, maintaining phosphoglucose isomerase (PGI) activity in the presence of PGI-inhibitory sugar alcohols; expression correlated with growth rate; GFP-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant displays increased glycogen accumulation; member of the haloacid dehalogenase (HAD) superfamily
Localization
Cell Percentages cytoplasm (98%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Pyp1

Pyp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pyp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available