Standard name
Human Ortholog
Description Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 0 0 0 0 0 0 0 0 0 0 0.12 0.06 0 0.06 0 0.06 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.06 0.05 0.06 0 0.05 0 0 0 0 0.05 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.09 0.08 0.05 0 0 0 0 0 0 0.08 0.06 0.12 0.1 0.09 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0.05 0.08 0 0 0 0 0 0 0 0 0 0 0.15 0.05 0.05 0 0.05 0.07 0 0 0 0 0 0
Endosome 0 0 0.23 0.05 0.16 0 0 0.08 0 0 0 0 0.14 0.19 0.15 0.16 0.17 0.1 0.13 0.1 0.09 0.06 0.06 0.09
Golgi 0.11 0.32 0.12 0.1 0 0 0 0 0 0 0 0 0.44 0.59 0.61 0.52 0.5 0.55 0.71 0.72 0.7 0.54 0.65 0.68
Mitochondria 0.98 0.87 0.78 0.85 0.81 0.94 0.95 0.87 0.93 0.98 0.95 0.95 0.33 0.18 0.16 0.08 0.12 0.09 0.11 0.11 0.05 0.26 0.17 0.14
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.1 0 0.06 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0.07 0.1 0.11 0.15 0.12 0.17 0 0 0 0.07 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 8 0 2 2 0 3 0 0 0 0 0 9 13 7 16 6 10 0 3 6 0 5 4
Bud 1 0 4 4 5 10 14 18 14 18 9 16 1 0 1 3 8 1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 3 2 2 3 5 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 2 0 0 0 1 1 2 3 4 0 2 0 5 1 1 0 0 0 0 0 0
Cytoplasm 4 3 2 16 15 15 15 12 11 6 13 12 6 14 24 29 14 17 0 0 0 0 4 2
Endoplasmic Reticulum 8 13 2 6 0 1 6 0 2 3 4 3 11 12 10 11 8 11 0 1 0 0 2 1
Endosome 1 3 36 9 31 3 3 27 3 0 1 1 10 41 31 45 27 17 23 16 16 3 10 18
Golgi 18 50 19 17 4 0 1 1 0 0 0 0 32 130 127 148 78 90 124 122 120 35 115 141
Mitochondria 168 135 120 148 161 267 371 283 261 301 302 320 24 39 33 22 18 14 20 18 8 17 30 28
Nucleus 0 0 0 0 0 0 1 5 2 1 1 1 0 0 1 1 1 1 0 0 0 0 0 0
Nuclear Periphery 0 0 1 4 0 1 1 1 1 1 0 1 1 2 0 2 1 2 0 1 0 0 0 0
Nucleolus 1 1 1 1 0 3 1 7 2 2 5 2 0 0 0 2 2 0 0 0 0 0 0 0
Peroxisomes 0 0 15 4 12 3 6 26 2 3 2 3 1 0 0 2 0 0 4 1 17 1 1 1
SpindlePole 0 0 4 0 1 3 6 14 7 4 3 3 2 5 4 9 1 2 0 0 0 0 0 0
Vac/Vac Membrane 7 8 4 2 5 7 8 10 12 9 7 11 5 22 23 43 18 28 0 3 0 4 5 7
Unique Cell Count 171 155 154 175 198 285 390 325 281 308 317 336 72 221 207 283 156 163 175 170 172 66 179 208
Labelled Cell Count 210 221 209 215 236 313 439 407 320 353 355 380 102 280 261 338 183 194 175 170 172 66 179 208


Early Golgi, Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 7.5 7.3 6.4 6.4 5.2 5.0 5.0 4.8 4.5 4.1 4.2 8.2 8.5 8.3 8.6 8.7 8.7 8.7 8.7 8.9
Std Deviation (1e-4) 0.8 1.2 1.3 1.4 2.1 1.4 1.2 1.5 1.1 1.0 1.2 1.2 1.0 1.0 1.1 1.5 1.6 1.5 0.8 1.2 1.2
Intensity Change (Log2) – – – -0.18 -0.18 -0.49 -0.55 -0.53 -0.62 -0.7 -0.83 -0.79 0.17 0.21 0.18 0.23 0.25 0.25 0.25 0.25 0.29

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud 0 0 0 0.6 1.4 0 – – – 0 0 0 0 1.2 0
Bud Neck 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum 0 0 0 0 0 0 – – – 0 2.1 1.9 0 0 2.4
Endosome -4.8 -1.8 -7.8 -9.2 -4.6 0 – – – -1.7 -1.1 -2.0 -1.9 -1.3 -3.1
Golgi -0.8 -3.9 -6.1 -6.7 -6.1 0 – – – 5.4 9.0 9.4 8.2 7.2 8.0
Mitochondria 1.5 0.8 4.9 6.1 2.6 0 – – – -6.5 -11.6 -11.8 -15.0 -11.8 -12.5
Nuclear Periphery 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes -2.9 -1.3 -4.4 -4.5 -0.6 0 – – – -2.3 -4.7 -4.6 -4.7 -4.0 -4.1
SpindlePole 0 0 0 0 0.9 0 – – – 0 0 0 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches 0 0 0 0 0 0 – – – 0 3.1 0 3.0 0 0
Cytoplasm 3.1 2.7 2.1 0 0 0 – – – 0 2.4 3.7 3.5 3.1 3.4
Nucleus 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0.9 – – – 0 2.8 3.0 4.1 3.1 4.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8655 2.4263 2.1211 1.5299 1.6733 2.1577 2.1217 2.5369 2.4867 2.2165 1.9478 2.4722 1.5618 1.6148 1.9847 2.0302 1.8127 2.033
Actin 0.0232 0.0007 0.018 0.0098 0.0064 0.0035 0.0371 0.0063 0.0093 0.0051 0.0074 0.0164 0.0561 0.0102 0.008 0.0014 0.0367 0.0057
Bud 0.0002 0.0001 0.0004 0.0003 0.0002 0.0001 0.0007 0.0002 0.0008 0.0004 0.0002 0.0002 0.0005 0.0002 0.0002 0.0002 0.0002 0.0001
Bud Neck 0.0004 0.0002 0.0005 0.0011 0.0007 0.0003 0.0044 0.0003 0.0005 0.0008 0.0004 0.0006 0.0023 0.0004 0.0004 0.0002 0.0008 0.0004
Bud Periphery 0.0002 0.0001 0.0005 0.0003 0.0003 0.0001 0.0009 0.0002 0.0012 0.0004 0.0002 0.0003 0.0007 0.0001 0.0001 0.0002 0.0004 0.0001
Bud Site 0.0005 0.0002 0.0012 0.0008 0.0007 0.0002 0.0121 0.0016 0.0013 0.0021 0.0004 0.0007 0.0061 0.0005 0.0002 0.0001 0.0003 0.0002
Cell Periphery 0.0001 0 0.0001 0.0002 0.0001 0 0.0004 0 0.0001 0.0001 0.0001 0.0001 0.0006 0.0001 0.0001 0 0.0002 0.0001
Cytoplasm 0.0033 0.0052 0.0047 0.0032 0.0029 0.0018 0.0058 0.0038 0.0051 0.0036 0.0042 0.0025 0.0059 0.0044 0.0024 0.0021 0.0011 0.0014
Cytoplasmic Foci 0.0865 0.1151 0.0862 0.0981 0.0783 0.0756 0.091 0.106 0.0846 0.0823 0.058 0.0792 0.11 0.1003 0.0815 0.079 0.0913 0.0541
Eisosomes 0.0002 0 0.0001 0.0001 0.0001 0 0.0004 0.0001 0.0001 0 0 0.0002 0.0012 0 0 0 0.0006 0.0001
Endoplasmic Reticulum 0.0016 0.0006 0.0011 0.0005 0.0023 0.0008 0.0087 0.0007 0.0024 0.0007 0.0013 0.0014 0.0038 0.001 0.0008 0.001 0.0053 0.0008
Endosome 0.2772 0.3011 0.2479 0.2801 0.2221 0.2002 0.2885 0.3381 0.2963 0.3657 0.343 0.2594 0.2435 0.3001 0.3177 0.3985 0.3618 0.2206
Golgi 0.4812 0.4965 0.5266 0.4562 0.5359 0.611 0.4346 0.4988 0.5318 0.5082 0.5375 0.5689 0.4046 0.5434 0.53 0.4563 0.4379 0.6544
Lipid Particles 0.0219 0.0103 0.0132 0.0123 0.0292 0.0186 0.0407 0.0151 0.0068 0.0059 0.0121 0.0148 0.0392 0.0088 0.0053 0.0077 0.0257 0.0211
Mitochondria 0.0561 0.0583 0.0645 0.0779 0.0568 0.0682 0.0284 0.0136 0.0448 0.0148 0.0192 0.041 0.0668 0.0192 0.0445 0.0204 0.013 0.0317
None 0.003 0.0002 0.006 0.0022 0.0046 0.0002 0.0023 0.0001 0.0003 0.0001 0.0001 0.0002 0.003 0.0001 0.0001 0.0001 0.0012 0.0001
Nuclear Periphery 0.003 0.0001 0.0005 0.0002 0.0106 0.0002 0.0067 0.0002 0.0007 0.0002 0.0003 0.0009 0.002 0.0001 0.0002 0.0002 0.0054 0.0002
Nucleolus 0.0002 0 0.0001 0.0125 0.0023 0.0001 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0005 0.0002 0 0 0.0001 0
Nucleus 0.0017 0 0.0002 0.0021 0.0051 0.0001 0.0008 0.0001 0.0002 0.0001 0.0001 0.0001 0.0009 0.0001 0.0001 0 0.0004 0
Peroxisomes 0.0325 0.0074 0.0222 0.0303 0.0131 0.0151 0.0228 0.0109 0.0062 0.0034 0.0089 0.0084 0.0419 0.0045 0.0034 0.0261 0.0034 0.0048
Punctate Nuclear 0.0016 0.0001 0.0013 0.0008 0.0232 0.0006 0.0019 0.0002 0.0002 0.0001 0.0002 0.0006 0.0037 0.0001 0.0001 0.0001 0.001 0.0001
Vacuole 0.0026 0.0015 0.0025 0.0091 0.0026 0.0013 0.0072 0.0017 0.0031 0.0024 0.003 0.0015 0.0038 0.0037 0.0021 0.0024 0.0058 0.0013
Vacuole Periphery 0.0027 0.0023 0.0023 0.002 0.0026 0.0019 0.0042 0.0019 0.004 0.0035 0.0034 0.0027 0.0027 0.0023 0.0029 0.0038 0.0074 0.0025

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.8352 6.5107 12.682 15.3359 12.9841 11.8286 11.9317 13.8846 11.5963 16.6501
Translational Efficiency 1.0681 1.8468 1.036 0.8299 0.8618 1.258 1.0229 1.0771 1.3217 1.064

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
203 176 145 1116 2108 1978 1047 1486 2311 2154 1192 2602

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 835.01 909.50 1099.59 952.48 861.28 907.88 1012.54 1035.20 858.97 908.01 1023.13 999.72
Standard Deviation 100.95 109.43 140.35 131.08 105.95 115.11 133.63 140.62 105.78 114.65 137.44 142.62
Intensity Change Log 2 — 0.123280 0.397100 0.189895 — 0.076019 0.233425 0.265355 — 0.099477 0.316316 0.228703

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001535 0.002205 0.006254 0.021359 0.000997 0.001196 0.006242 0.014273 0.001044 0.001278 0.006243 0.017312
Bud Neck 0.000238 0.000283 0.001063 0.001236 0.000060 0.000096 0.000416 0.001338 0.000076 0.000111 0.000495 0.001295
Bud Site 0.002490 0.002167 0.005006 0.019224 0.000489 0.000915 0.006019 0.016734 0.000664 0.001018 0.005896 0.017802
Cell Periphery 0.000094 0.000143 0.000137 0.000138 0.000063 0.000049 0.000075 0.000069 0.000065 0.000057 0.000082 0.000098
Cytoplasm 0.001150 0.000606 0.001899 0.009251 0.000518 0.001275 0.002657 0.009812 0.000573 0.001221 0.002565 0.009571
Cytoplasmic Foci 0.175424 0.181975 0.269748 0.250915 0.137436 0.149088 0.283843 0.275104 0.140773 0.151775 0.282128 0.264729
Eisosomes 0.000096 0.000073 0.000052 0.000146 0.000046 0.000032 0.000053 0.000081 0.000050 0.000036 0.000053 0.000109
Endoplasmic Reticulum 0.000305 0.000296 0.002479 0.003281 0.000401 0.000284 0.003273 0.000681 0.000393 0.000285 0.003176 0.001796
Endosome 0.166038 0.200239 0.222076 0.189977 0.111494 0.151126 0.155754 0.199714 0.116285 0.155139 0.163822 0.195538
Golgi 0.586805 0.587128 0.325950 0.387326 0.677019 0.642734 0.468533 0.370837 0.669095 0.638191 0.451188 0.377909
Lipid Particles 0.003587 0.004488 0.039645 0.003758 0.004723 0.003018 0.005347 0.003243 0.004623 0.003138 0.009519 0.003464
Mitochondria 0.041961 0.010155 0.004237 0.016431 0.045603 0.030970 0.008959 0.014964 0.045283 0.029269 0.008384 0.015593
Mitotic Spindle 0.005286 0.000600 0.032557 0.021466 0.000973 0.001288 0.011787 0.027936 0.001352 0.001232 0.014313 0.025161
None 0.000031 0.000011 0.000091 0.000025 0.000048 0.000040 0.000022 0.000023 0.000046 0.000038 0.000031 0.000024
Nuclear Periphery 0.000030 0.000012 0.000564 0.000075 0.000087 0.000031 0.000139 0.000097 0.000082 0.000029 0.000191 0.000088
Nuclear Periphery Foci 0.000225 0.000094 0.011930 0.000569 0.000361 0.000142 0.001227 0.000441 0.000349 0.000138 0.002529 0.000496
Nucleolus 0.000168 0.000004 0.001248 0.000023 0.000039 0.000006 0.000023 0.000026 0.000050 0.000006 0.000172 0.000025
Nucleus 0.000268 0.000008 0.000468 0.000244 0.000025 0.000016 0.000082 0.000197 0.000046 0.000015 0.000129 0.000217
Peroxisomes 0.007023 0.002037 0.012167 0.017912 0.001400 0.001479 0.004557 0.022330 0.001894 0.001524 0.005483 0.020435
Vacuole 0.002475 0.003697 0.040049 0.046057 0.005012 0.006580 0.028670 0.035758 0.004789 0.006345 0.030054 0.040175
Vacuole Periphery 0.004772 0.003780 0.022381 0.010586 0.013206 0.009634 0.012325 0.006340 0.012465 0.009155 0.013548 0.008161

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.95 -1.17 -7.54 -7.21 -3.17 -0.48 -3.70 -7.33 -7.12 -3.51 -0.61 -3.88 -10.65 -10.32 -5.48
Bud Neck -0.23 -3.54 -6.45 -5.43 -1.09 -1.58 -7.32 -6.69 -6.48 -4.76 -1.35 -8.26 -10.20 -9.82 -6.43
Bud Site 0.15 -1.26 -6.87 -8.62 -7.94 -2.43 -8.93 -11.16 -10.81 -6.93 -1.45 -9.10 -15.48 -15.14 -9.90
Cell Periphery -0.86 -1.26 -1.94 0.10 0.00 1.28 -1.17 -0.69 -2.31 0.65 0.79 -1.68 -3.24 -3.99 -1.62
Cytoplasm 0.85 -1.12 -6.99 -8.28 -6.99 -1.66 -6.54 -10.42 -8.42 -7.76 -1.55 -6.75 -13.29 -10.38 -9.88
Cytoplasmic Foci -0.49 -5.84 -7.07 -6.25 1.42 -3.40 -27.75 -27.63 -24.51 1.46 -3.29 -28.24 -31.12 -27.22 3.31
Eisosomes 0.93 1.96 -1.89 -3.35 -4.99 2.70 -1.15 -5.27 -9.23 -4.43 2.89 -0.44 -6.56 -9.15 -6.55
Endoplasmic Reticulum 0.15 -4.07 -3.85 -3.88 -0.88 1.56 -3.66 -1.59 -2.17 3.22 1.56 -4.01 -4.06 -4.34 1.82
Endosome -2.35 -3.34 -2.20 0.96 2.27 -10.71 -10.24 -17.49 -9.06 -7.52 -10.71 -10.98 -19.83 -9.23 -6.29
Golgi -0.03 10.50 12.06 11.85 -2.64 5.35 24.91 37.58 33.16 10.19 5.00 27.07 43.67 38.77 9.02
Lipid Particles -0.40 -3.38 -0.31 0.27 3.36 1.91 -0.62 1.60 -0.47 2.04 1.78 -3.00 1.43 -0.72 3.81
Mitochondria 3.73 4.68 3.16 -1.50 -4.05 4.18 11.85 9.70 6.21 -2.98 4.86 12.75 10.16 5.86 -4.08
Mitotic Spindle 1.26 -3.01 -3.56 -7.53 1.07 -1.07 -7.03 -9.85 -9.72 -5.29 0.34 -7.57 -11.96 -12.16 -4.57
None 2.16 -0.88 0.64 -3.87 0.95 0.32 2.40 2.12 0.65 -0.53 0.39 0.86 2.22 0.59 0.71
Nuclear Periphery 1.87 -3.59 -4.24 -6.69 3.21 1.54 -1.18 -0.38 -3.45 1.10 1.59 -2.46 -0.41 -5.09 2.91
Nuclear Periphery Foci 1.19 -2.56 -2.81 -5.48 2.47 1.78 -3.27 -0.72 -2.99 2.92 1.88 -3.58 -1.49 -5.03 3.30
Nucleolus 1.04 -1.04 0.91 -6.25 1.17 1.13 0.55 0.41 -6.88 -0.69 1.48 -0.96 0.82 -8.82 1.14
Nucleus 1.07 -0.59 -0.01 -3.25 0.69 0.91 -3.07 -1.78 -1.84 -1.41 1.32 -1.74 -2.50 -2.90 -1.47
Peroxisomes 2.66 -1.17 -4.30 -8.46 -1.28 -0.28 -4.45 -10.73 -10.65 -8.63 1.19 -4.41 -13.51 -13.78 -9.57
Vacuole -1.12 -6.03 -13.85 -13.01 -1.56 -2.59 -10.67 -13.65 -12.80 -2.87 -2.77 -12.06 -18.93 -17.82 -4.62
Vacuole Periphery 0.81 -3.30 -4.98 -4.83 2.21 3.51 0.70 7.72 4.26 5.67 3.53 -0.84 5.10 1.39 4.67
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
Localization
Cell Percentages Golgi (15%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Cog5

Cog5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cog5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available