Standard name
Human Ortholog
Description Dihydrolipoamide acetyltransferase component (E2) of the PDC; the pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – – – 0 0 0 0 – 0 0 0 – – 0 0 0 – 0 0.06 0 0.06 0 0.05
Bud – – – – 0 0 0 0 – 0 0 0 – – 0 0.1 0.06 – 0.05 0.09 0 0.05 0 0
Bud Neck – – – – 0 0 0 0 – 0 0 0 – – 0 0 0.06 – 0.05 0 0 0 0 0
Bud Site – – – – 0 0.1 0 0 – 0 0 0 – – 0 0 0.06 – – – – – – –
Cell Periphery – – – – 0 0 0 0 – 0 0 0 – – 0 0.05 0.12 – 0 0 0 0 0 0
Cytoplasm – – – – 0.11 0.05 0.18 0.11 – 0.17 0.12 0.05 – – 0 0.05 0.06 – 0.09 0 0 0 0 0
Endoplasmic Reticulum – – – – 0 0 0 0 – 0 0 0 – – 0 0.05 0 – 0 0 0 0.06 0 0
Endosome – – – – 0 0 0 0 – 0 0 0 – – 0.16 0.2 0.12 – 0.09 0.09 0.14 0 0 0.05
Golgi – – – – 0 0 0 0 – 0 0 0 – – 0.24 0.3 0 – 0 0.1 0.1 0.06 0.14 0.19
Mitochondria – – – – 0.78 0.9 0.77 0.83 – 0.67 0.85 0.88 – – 0.52 0.05 0.12 – 0.5 0.62 0.64 0.53 0.54 0.55
Nucleus – – – – 0 0 0 0 – 0.06 0 0 – – 0 0 0.06 – 0 0 0 0 0 0
Nuclear Periphery – – – – 0 0.05 0.1 0.12 – 0.19 0.1 0.07 – – 0 0 0 – 0.1 0 0 0 0 0
Nucleolus – – – – 0.17 0.1 0.12 0.15 – 0.24 0.1 0.14 – – 0 0.05 0.12 – 0 0 0 0 0 0
Peroxisomes – – – – 0 0.08 0 0 – 0 0 0 – – 0.08 0.2 0.29 – 0 0 0.08 0.07 0.09 0.06
SpindlePole – – – – 0 0.05 0 0 – 0 0 0 – – 0.08 0.05 0.06 – 0 0.05 0 0 0 0
Vac/Vac Membrane – – – – 0 0.05 0 0 – 0 0 0 – – 0.16 0.1 0.06 – 0.05 0 0 0 0.07 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – – – 0 1 0 0 – 0 0 0 – – 0 0 0 – 0 0 0 1 2 4
Bud – – – – 0 1 1 2 – 1 1 1 – – 0 2 1 – 0 1 0 1 0 0
Bud Neck – – – – 0 0 0 0 – 0 0 0 – – 0 0 1 – 0 0 0 0 0 0
Bud Site – – – – 0 4 1 0 – 1 0 1 – – 0 0 1 – – – – – – –
Cell Periphery – – – – 0 0 0 1 – 0 0 0 – – 0 1 2 – 0 0 0 0 0 0
Cytoplasm – – – – 5 2 17 12 – 9 7 3 – – 0 1 1 – 0 0 0 0 0 1
Endoplasmic Reticulum – – – – 0 0 2 0 – 0 1 1 – – 0 1 0 – 0 0 0 1 0 1
Endosome – – – – 2 0 0 0 – 0 0 0 – – 4 4 2 – 0 1 5 0 1 4
Golgi – – – – 1 0 0 0 – 0 0 1 – – 6 6 0 – 0 1 3 1 9 16
Mitochondria – – – – 36 35 75 87 – 36 51 49 – – 13 1 2 – 5 9 23 15 33 47
Nucleus – – – – 0 1 0 3 – 3 0 2 – – 1 0 1 – 0 0 0 0 1 0
Nuclear Periphery – – – – 0 2 10 13 – 10 6 4 – – 0 0 0 – 0 0 0 1 0 0
Nucleolus – – – – 8 4 12 16 – 13 6 8 – – 1 1 2 – 0 0 0 0 1 0
Peroxisomes – – – – 2 3 1 0 – 0 1 1 – – 2 4 5 – 0 0 3 1 5 5
SpindlePole – – – – 1 2 2 0 – 0 1 1 – – 2 1 1 – 0 0 0 0 0 0
Vac/Vac Membrane – – – – 0 2 2 4 – 1 0 0 – – 4 2 1 – 0 0 0 0 4 1
Unique Cell Count 46 39 97 105 54 60 56 25 20 17 10 15 37 30 63 87
Labelled Cell Count 55 57 123 138 74 74 72 33 24 20 10 15 37 30 63 87


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – – – – 6.9 6.0 6.2 6.0 – 6.5 7.2 7.6 – – 10.0 8.5 7.8 – – 15.5 15.2
Std Deviation (1e-4) – – – – 3.0 1.5 2.5 1.8 – 1.8 2.6 2.5 – – 2.3 2.1 2.4 – – 9.5 6.1
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0264 0.003 0.0113 0.0007 0.0056 0.0119 0.2453 0.0008 0.0064 0.0115 0.0001 0.0005 – – – – – –
Bud 0.0004 0.0008 0.0001 0 0 0.0004 0.0003 0 0.0054 0.0004 0 0 – – – – – –
Bud Neck 0.0006 0.0001 0.0001 0.0001 0 0.0001 0.0003 0 0.0003 0.0003 0 0 – – – – – –
Bud Periphery 0.0007 0.0009 0.0002 0.0001 0.0001 0.0008 0.0006 0.0002 0.0104 0.0003 0 0 – – – – – –
Bud Site 0.0011 0.0017 0.0005 0.0001 0.0001 0.0004 0.0011 0 0.0053 0.0024 0 0 – – – – – –
Cell Periphery 0.0003 0.0004 0.0002 0.0001 0 0.0001 0.0003 0.0001 0.0007 0.0001 0 0 – – – – – –
Cytoplasm 0.0019 0 0.0012 0 0.0024 0.0001 0.0004 0 0.0004 0.0004 0 0 – – – – – –
Cytoplasmic Foci 0.0147 0.0014 0.0109 0.0011 0.0028 0.0007 0.0084 0.0004 0.0188 0.0355 0 0.0002 – – – – – –
Eisosomes 0.0005 0.0004 0.0007 0.0001 0.0001 0.0001 0.001 0.0001 0.0002 0.0001 0.0001 0.0001 – – – – – –
Endoplasmic Reticulum 0.0035 0.0001 0.0004 0 0.0051 0.0003 0.0023 0 0.0002 0.0001 0 0 – – – – – –
Endosome 0.0266 0.0023 0.0077 0.0029 0.0483 0.0046 0.0055 0.0003 0.0189 0.0079 0 0.0004 – – – – – –
Golgi 0.0183 0.0061 0.0257 0.0049 0.0064 0.011 0.0143 0.0007 0.0306 0.021 0.0002 0.0029 – – – – – –
Lipid Particles 0.0256 0.0229 0.0243 0.0094 0.007 0.0018 0.0761 0.0072 0.0171 0.0139 0 0.0115 – – – – – –
Mitochondria 0.8329 0.9311 0.8978 0.9727 0.8784 0.9652 0.3758 0.9646 0.8104 0.897 0.9994 0.9814 – – – – – –
None 0.0021 0 0.0018 0 0.0029 0 0.0011 0 0.0007 0.0001 0 0 – – – – – –
Nuclear Periphery 0.016 0.0001 0.0002 0 0.0265 0.0001 0.1659 0 0.0005 0.0001 0 0 – – – – – –
Nucleolus 0.0006 0.0014 0.0007 0.0001 0.0001 0 0.0069 0.0002 0.002 0.0003 0 0 – – – – – –
Nucleus 0.0044 0.0003 0.0002 0.0001 0.0013 0 0.0096 0.0001 0.0007 0.0002 0 0 – – – – – –
Peroxisomes 0.0094 0.0135 0.0112 0.0042 0.007 0.0005 0.0362 0.0194 0.0559 0.0068 0.0002 0.0021 – – – – – –
Punctate Nuclear 0.0011 0 0.0008 0 0.0022 0 0.0048 0 0.0111 0.0009 0 0 – – – – – –
Vacuole 0.0061 0.0051 0.0011 0.0007 0.0008 0.0003 0.0032 0.0011 0.0023 0.0003 0 0.0001 – – – – – –
Vacuole Periphery 0.0068 0.0084 0.0029 0.0028 0.0028 0.0014 0.0407 0.0046 0.0017 0.0004 0 0.0007 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 214.7412 214.4296 197.5059 217.7601 178.7031 231.3659 231.0914 233.6664 250.6124 231.6136
Translational Efficiency 1.6756 1.6399 1.8199 1.6765 1.9909 1.5516 1.4601 1.7213 1.6032 1.595

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1110 451 1985 348 1361 748 2405 258 2471 1199 4390 606

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 751.42 998.15 1138.74 1729.54 866.77 898.74 1453.72 2000.88 814.95 936.13 1311.30 1845.06
Standard Deviation 113.65 209.01 178.33 356.13 166.25 169.16 299.70 458.64 155.94 191.32 296.92 424.72
Intensity Change Log 2 — 0.409637 0.599747 1.202697 — 0.052255 0.746028 1.206914 — 0.229255 0.679941 1.204957

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000775 0.008136 0.006203 0.016177 0.001927 0.005921 0.005696 0.025225 0.001409 0.006754 0.005925 0.020029
Bud Neck 0.013573 0.020807 0.001210 0.005559 0.002579 0.016547 0.000314 0.004558 0.007518 0.018149 0.000719 0.005133
Bud Site 0.015964 0.046057 0.005752 0.004981 0.005636 0.034187 0.000430 0.004714 0.010275 0.038651 0.002837 0.004868
Cell Periphery 0.000516 0.000591 0.000206 0.000523 0.001064 0.001547 0.000082 0.000629 0.000818 0.001188 0.000138 0.000568
Cytoplasm 0.008163 0.007245 0.001578 0.000399 0.001261 0.005868 0.000172 0.000349 0.004361 0.006386 0.000808 0.000378
Cytoplasmic Foci 0.057313 0.059572 0.040349 0.020334 0.023898 0.039690 0.008903 0.017347 0.038909 0.047168 0.023121 0.019062
Eisosomes 0.000093 0.000151 0.000081 0.000899 0.000094 0.000145 0.000278 0.003619 0.000094 0.000147 0.000189 0.002057
Endoplasmic Reticulum 0.000629 0.000875 0.000769 0.004279 0.000379 0.000707 0.000156 0.003214 0.000491 0.000770 0.000433 0.003825
Endosome 0.127599 0.139071 0.035788 0.016311 0.047435 0.112669 0.004676 0.014588 0.083446 0.122600 0.018744 0.015578
Golgi 0.077027 0.068746 0.116101* 0.277455* 0.030824 0.050770 0.057957 0.290739* 0.051579 0.057531 0.084248 0.283111*
Lipid Particles 0.016231 0.006078 0.003200 0.018666 0.014204 0.010973 0.001690 0.005682 0.015114 0.009132 0.002373 0.013138
Mitochondria 0.533547* 0.462149* 0.704030* 0.545178* 0.809354* 0.568685* 0.902514* 0.550691* 0.685459* 0.528612* 0.812767* 0.547525*
Mitotic Spindle 0.019500 0.035609 0.019469 0.007417 0.004197 0.017536 0.000888 0.002365 0.011071 0.024334 0.009290 0.005266
None 0.001825 0.000952 0.000501 0.004308 0.000403 0.000521 0.001087 0.004858 0.001042 0.000683 0.000822 0.004542
Nuclear Periphery 0.000317 0.000756 0.001979 0.002787 0.000250 0.000277 0.000314 0.001236 0.000280 0.000457 0.001067 0.002127
Nuclear Periphery Foci 0.000883 0.001538 0.001143 0.001664 0.000569 0.000725 0.000147 0.000599 0.000710 0.001031 0.000597 0.001211
Nucleolus 0.001942 0.002716 0.000075 0.000280 0.000819 0.003469 0.000032 0.000468 0.001324 0.003185 0.000051 0.000360
Nucleus 0.003364 0.002975 0.000069 0.000197 0.000779 0.004303 0.000010 0.000331 0.001940 0.003804 0.000037 0.000254
Peroxisomes 0.083560 0.087066 0.007076 0.002571 0.041167 0.077221 0.002526 0.008150 0.060210 0.080924 0.004584 0.004946
Vacuole 0.021248 0.034850 0.020479 0.021723 0.007041 0.034274 0.002894 0.020006 0.013423 0.034491 0.010845 0.020992
Vacuole Periphery 0.015931 0.014062 0.033942 0.048293 0.006120 0.013966 0.009234 0.040630 0.010527 0.014002 0.020406 0.045030

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.77 -6.64 -4.58 -1.86 -2.88 -2.47 -3.58 -4.99 -3.96 -4.14 -3.80 -6.59 -6.70 -4.30 -4.98
Bud Neck -2.35 7.78 3.70 5.02 -2.93 -7.40 5.65 -1.54 5.17 -3.29 -6.25 8.99 1.82 7.04 -4.38
Bud Site -5.48 5.36 3.39 7.01 0.01 -7.57 5.18 0.21 6.88 -2.19 -9.00 7.26 2.46 9.67 -1.57
Cell Periphery -0.80 5.15 -0.05 0.52 -2.46 -0.52 1.47 0.65 1.39 -5.70 -0.68 1.84 0.66 1.49 -5.11
Cytoplasm 0.13 4.98 5.98 4.29 2.70 -3.31 4.57 3.42 3.97 -1.92 -1.87 5.79 6.53 5.72 1.89
Cytoplasmic Foci -0.42 4.79 9.38 7.33 6.19 -4.72 8.58 1.77 5.16 -2.75 -2.75 8.25 7.66 8.64 1.79
Eisosomes -5.22 2.15 -7.78 -7.19 -7.90 -2.96 -6.39 -3.11 -3.06 -2.95 -4.97 -5.92 -4.02 -3.91 -3.82
Endoplasmic Reticulum -1.57 -1.17 -3.10 -2.87 -2.98 -4.00 4.35 -6.18 -5.42 -6.70 -3.51 0.94 -4.75 -4.33 -4.83
Endosome -1.11 16.95 20.10 14.18 7.84 -9.47 13.84 7.99 14.50 -3.57 -6.69 20.98 20.01 20.35 1.75
Golgi 1.32 -6.87 -11.98 -12.23 -9.59 -4.94 -7.41 -13.63 -12.45 -12.12 -1.61 -9.84 -18.49 -17.79 -15.77
Lipid Particles 4.52 6.45 -0.62 -3.56 -4.56 1.18 6.78 4.07 2.43 -3.89 3.19 9.35 0.83 -1.66 -5.37
Mitochondria 3.43 -12.63 -0.52 -3.14 7.41 14.84 -10.12 10.95 0.68 15.57* 11.81 -14.96 8.33 -1.06 17.10*
Mitotic Spindle -3.17 -0.04 3.26 5.05 3.46 -6.01 4.68 1.38 6.31 -1.32 -5.46 1.32 2.77 6.67 2.02
None 0.82 2.31 -3.48 -4.55 -9.33 -1.88 -10.42 -8.20 -7.97 -6.94 0.82 0.86 -8.31 -9.66 -11.29
Nuclear Periphery -0.81 -3.23 -5.37 -2.96 -1.22 -0.39 -0.62 -5.03 -4.88 -4.36 -0.84 -3.29 -6.71 -4.99 -3.00
Nuclear Periphery Foci -0.92 -0.83 -2.20 -0.15 -1.42 -0.71 2.09 -0.13 0.94 -4.24 -1.07 0.65 -2.24 -0.55 -3.05
Nucleolus -0.65 4.45 3.96 2.43 -2.47 -2.60 2.65 0.79 2.92 -1.37 -2.39 5.12 3.47 3.88 -2.12
Nucleus 0.20 3.58 3.43 3.33 -1.47 -2.63 2.91 1.21 2.93 -1.30 -1.99 4.31 3.70 3.95 -1.87
Peroxisomes -0.39 15.32 15.86 10.74 2.82 -5.58 11.96 6.38 9.98 -1.60 -3.86 19.22 16.13 15.38 -0.32
Vacuole -3.45 0.33 -0.15 2.69 -0.36 -8.20 4.84 -2.60 2.24 -3.43 -8.16 2.37 -2.58 3.49 -3.49
Vacuole Periphery 0.90 -7.93 -6.72 -7.05 -2.89 -4.91 -3.63 -6.38 -4.77 -5.79 -2.66 -8.62 -9.66 -8.45 -6.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Dihydrolipoamide acetyltransferase component (E2) of the PDC; the pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Lat1

Lat1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Lat1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available