Standard name
Human Ortholog
Description Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.45 0.38 0.34 0.19 0.26 0 0.06 0 0.05 0.08 0 0.05 0.5 0.31 0.29 0.28 0.24 0.35 0.14 0.24 0.2 0.08 0.1 0.11
Bud 0.19 0.24 0.21 0.23 0.18 0.18 0.25 0.22 0.22 0.2 0.15 0.13 0.16 0.13 0.17 0.13 0.13 0.14 0.29 0.26 0.25 0.25 0.22 0.27
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.11 0 0.46 0.42 0.44 0.54 0.56 0.47
Bud Site 0.47 0.17 0.34 0.35 0.4 0.28 0.28 0.21 0.17 0.12 0.15 0.23 0.32 0.15 0.16 0.22 0.23 0.23 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.1 0.14 0.12 0.14 0.12 0.26 0.17 0.16 0.16 0.16 0.1 0.16 0.23 0.28 0.36 0.26 0.3 0.29 0.05 0 0 0 0 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.07 0.1 0.09 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.52 0 0.12 0.16 0.3 0.21 0.39 0.42 0.52 0.71 0.77 0.73 0 0 0 0.16 0.08 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0.07 0 0 0.08 0.08 0 0 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.24 0.31 0.47 0.37 0.31 0.33 0.23 0.19 0.16 0.11 0.11 0.13 0.07 0.1 0.06 0.16 0.06 0.1 0 0 0 0 0 0
SpindlePole 0 0.07 0.17 0.19 0.14 0.16 0.18 0.2 0.16 0 0.09 0.1 0.1 0.31 0.22 0.24 0.15 0.14 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 26 11 20 11 28 3 10 4 7 13 2 6 61 72 72 54 51 48 11 21 17 13 23 31
Bud 11 7 12 13 19 21 42 46 31 30 22 17 20 30 42 25 27 19 24 22 21 42 48 75
Bud Neck 0 0 0 2 1 0 5 2 1 2 0 1 2 11 10 4 24 2 38 36 38 93 123 131
Bud Site 27 5 20 20 42 33 47 44 24 19 22 29 39 35 39 44 49 31 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 0 0 2 1 3 10 3 1 0 0 0 0 2
Cytoplasm 6 4 7 8 13 30 28 34 23 25 15 20 28 64 90 50 64 40 4 1 1 4 8 17
Endoplasmic Reticulum 1 1 0 1 3 1 1 0 0 1 1 0 4 7 4 4 8 3 0 0 0 0 0 0
Endosome 0 2 6 5 1 0 2 7 2 0 0 0 1 3 0 7 9 1 1 1 1 3 5 5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 6 3 0 0 0 0 0 1
Mitochondria 30 1 7 9 32 24 66 90 73 109 116 92 2 0 0 31 16 10 0 1 2 1 2 6
Nucleus 1 0 0 4 4 3 14 17 5 1 8 1 3 1 5 8 11 2 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 1 0 0 2 1 1 0 0 0 0 0 0 0 0 0 1 1 0
Nucleolus 1 1 1 1 0 3 3 8 3 3 3 5 0 1 0 2 5 0 0 0 0 1 0 1
Peroxisomes 14 9 27 21 33 39 38 40 23 17 16 16 9 24 16 32 12 14 1 0 0 1 0 0
SpindlePole 1 2 10 11 15 19 31 43 23 5 13 12 12 71 55 48 32 19 0 0 1 1 1 0
Vac/Vac Membrane 0 0 1 0 0 1 0 2 1 2 0 0 0 1 5 3 7 5 0 0 0 2 3 4
Unique Cell Count 58 29 58 57 106 117 168 213 140 153 151 126 123 231 251 196 210 136 85 87 86 172 222 282
Labelled Cell Count 118 43 111 106 191 177 288 338 216 229 219 200 181 322 339 318 331 200 85 87 86 172 222 282


Bud Neck, Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.2 7.0 5.7 5.2 5.4 4.6 4.1 3.8 3.7 3.5 3.0 3.1 6.9 6.5 6.0 7.5 7.4 7.2 7.3 7.8 8.0
Std Deviation (1e-4) 0.8 1.2 2.1 1.9 2.8 2.7 2.2 1.5 1.6 1.4 1.0 1.1 1.1 1.1 1.2 1.9 2.5 1.7 1.4 1.2 1.7
Intensity Change (Log2) – – – -0.14 -0.09 -0.33 -0.5 -0.6 -0.62 -0.7 -0.93 -0.88 0.26 0.17 0.06 0.39 0.36 0.32 0.35 0.45 0.47


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.8 -1.1 0 0 0 0 0 0 0 1.9 -0.5 -0.9 -1.0 -1.6 0.1
Bud 0.3 -0.4 0 0 0 0 0 0 0 -0.7 -1.5 -0.7 -1.5 -1.5 -1.2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 2.7 0
Bud Site 0.1 0.6 0 0 0 0 0 0 0 -0.4 -3.4 -3.3 -1.9 -1.7 -1.7
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.3 0 2.1 0.8 0.7 0.8 0.8 -0.5 0.7 1.7 2.5 3.5 2.2 2.8 2.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -0.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.6 2.6 0 0 0 0 0 0 0 0 0 0 0.7 0 -1.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes -1.1 -2.0 0 0 0 0 0 0 0 -6.2 -6.5 -8.0 -4.8 -7.8 -5.7
SpindlePole 0.3 -0.5 0 0 0 0 0 0 0 -1.4 2.0 0.8 1.2 -0.4 -0.6
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3491 2.5237 1.1358 0.4307 0.4923 1.6963 1.9487 2.5466 1.6552 1.2582 0.409 2.1554 1.1482 1.5674 0.4105 0.321 0.0612 1.3262
Actin 0.0476 0.0829 0.0398 0.0269 0.0276 0.0653 0.1974 0.0662 0.079 0.0316 0.0326 0.0755 0.0816 0.0701 0.0301 0.031 0.0041 0.072
Bud 0.0045 0.0145 0.006 0.0029 0.0015 0.0022 0.0056 0.0048 0.0057 0.0035 0.0026 0.0014 0.0072 0.0155 0.0054 0.0024 0.0034 0.0023
Bud Neck 0.2635 0.0211 0.4277 0.6457 0.6513 0.8684 0.2029 0.0271 0.3676 0.6046 0.4847 0.8333 0.2692 0.0463 0.4702 0.7811 0.7765 0.8755
Bud Periphery 0.0067 0.0309 0.0128 0.0048 0.0037 0.0045 0.0104 0.0056 0.0062 0.0057 0.0049 0.0037 0.01 0.0129 0.0082 0.0054 0.0048 0.004
Bud Site 0.4744 0.7855 0.2946 0.0904 0.0391 0.0165 0.322 0.7259 0.3435 0.1135 0.0665 0.0083 0.4995 0.8177 0.3672 0.0821 0.1056 0.0185
Cell Periphery 0.0038 0.0094 0.0037 0.0017 0.004 0.0018 0.0044 0.0054 0.0031 0.0048 0.0099 0.0015 0.0046 0.0042 0.0022 0.0016 0.0017 0.0011
Cytoplasm 0.0439 0.0196 0.05 0.0177 0.0041 0.0056 0.0802 0.1146 0.0906 0.0684 0.0323 0.0248 0.046 0.027 0.0362 0.0062 0.0954 0.0103
Cytoplasmic Foci 0.0399 0.0045 0.0298 0.0584 0.1059 0.0157 0.0157 0.0032 0.0219 0.0614 0.1972 0.0125 0.0338 0.0018 0.024 0.0362 0.0029 0.0086
Eisosomes 0.0014 0.0002 0.0022 0.0004 0.0005 0.0003 0.0013 0.0002 0.0004 0.0002 0.0007 0.0002 0.0005 0.0002 0.0003 0.0002 0 0.0001
Endoplasmic Reticulum 0.0025 0.0014 0.0009 0.0004 0.0001 0.0001 0.0052 0.001 0.0012 0.0017 0.0013 0.0007 0.0024 0.0001 0.0003 0.0001 0.0003 0.0002
Endosome 0.0079 0.0004 0.0011 0.0011 0.0024 0.002 0.0185 0.0009 0.0114 0.0437 0.0165 0.0091 0.0039 0.0002 0.0017 0.0002 0.0004 0.0018
Golgi 0.0026 0.0007 0.0014 0.0019 0.0048 0.0023 0.0148 0.0011 0.0102 0.0181 0.0268 0.0063 0.0021 0.0008 0.001 0.0007 0.0005 0.0016
Lipid Particles 0.0034 0.0001 0.0007 0.0016 0.0036 0.0005 0.0217 0.0002 0.0062 0.002 0.003 0.0072 0.0016 0.0002 0.0004 0.0002 0.0002 0.0002
Mitochondria 0.0023 0.0014 0.0009 0.0014 0.0024 0.0006 0.0127 0.0002 0.0125 0.0059 0.0016 0.0006 0.0009 0.0003 0.0003 0.0003 0.0001 0.0001
None 0.0728 0.0205 0.1139 0.1193 0.07 0.0069 0.0101 0.0411 0.0263 0.0038 0.0845 0.0038 0.0237 0.0005 0.0353 0.0445 0.0015 0.0003
Nuclear Periphery 0.002 0.0003 0.0003 0.0002 0 0 0.0203 0.0003 0.0014 0.0008 0.0003 0.001 0.0037 0.0001 0.0002 0 0 0.0001
Nucleolus 0.0029 0.0003 0.0015 0.0013 0.0047 0.0003 0.008 0.0002 0.0007 0.0004 0.0006 0.0002 0.0005 0.0001 0.0008 0.0005 0.0005 0.0001
Nucleus 0.0026 0.0008 0.0015 0.0014 0.0012 0.0002 0.0135 0.0006 0.0011 0.0009 0.001 0.0026 0.0017 0.0004 0.0013 0.0003 0.0005 0.0002
Peroxisomes 0.0085 0.0044 0.0076 0.0174 0.063 0.0058 0.0205 0.0003 0.0079 0.0055 0.0128 0.0021 0.0029 0.0008 0.0021 0.0019 0.0007 0.0021
Punctate Nuclear 0.0048 0.0002 0.0028 0.0046 0.009 0.0008 0.0088 0.0003 0.0021 0.0038 0.0177 0.0047 0.0027 0.0004 0.012 0.0047 0.0002 0.0002
Vacuole 0.0018 0.0009 0.0007 0.0005 0.0011 0.0002 0.004 0.0006 0.001 0.0159 0.0025 0.0004 0.0014 0.0003 0.0007 0.0003 0.0005 0.0006
Vacuole Periphery 0.0003 0.0001 0.0001 0.0001 0.0001 0 0.002 0.0001 0.0003 0.0036 0.0003 0.0001 0.0003 0 0.0001 0 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.6625 12.0879 23.9194 87.8736 41.4924 5.4059 7.3333 10.1739 58.5611 46.0577
Translational Efficiency 0.3315 0.1731 1.0269 0.6724 0.7465 0.612 0.4634 0.6127 0.9742 0.9582

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
168 1318 1991 1243 173 2059 482 1623 341 3377 2473 2866

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 764.77 791.11 908.96 856.92 783.80 814.17 1000.90 835.87 774.42 805.17 926.88 845.00
Standard Deviation 100.04 123.78 118.05 105.86 84.89 101.12 114.99 116.72 93.15 111.09 122.97 112.62
Intensity Change Log 2 — 0.048852 0.249191 0.164135 — 0.054844 0.352740 0.092793 — 0.051888 0.302530 0.128466

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002814 0.012083 0.004956 0.006158 0.003904 0.005168 0.007792 0.004371 0.003367 0.007867 0.005509 0.005146
Bud Neck 0.369683* 0.175280 0.262455* 0.260103* 0.253336* 0.310905* 0.239840* 0.227753* 0.310657* 0.257972* 0.258047* 0.241783*
Bud Site 0.435719* 0.583484* 0.541247* 0.578881* 0.441911* 0.543018* 0.557354* 0.562971* 0.438860* 0.558811* 0.544386* 0.569872*
Cell Periphery 0.005129 0.004236 0.001554 0.000743 0.004467 0.004720 0.001264 0.000835 0.004793 0.004531 0.001497 0.000795
Cytoplasm 0.052212 0.093779 0.096658 0.058535 0.106500* 0.061446 0.058091 0.097196 0.079754 0.074065 0.089141 0.080429
Cytoplasmic Foci 0.042975 0.041274 0.010938 0.014573 0.081263 0.018926 0.016172 0.018958 0.062400 0.027648 0.011958 0.017057
Eisosomes 0.000239 0.000254 0.000126 0.000101 0.000299 0.000197 0.000193 0.000100 0.000270 0.000219 0.000140 0.000101
Endoplasmic Reticulum 0.000107 0.000356 0.000443 0.000547 0.001013 0.000175 0.001134 0.000320 0.000567 0.000246 0.000578 0.000418
Endosome 0.028966 0.018271 0.006023 0.008569 0.014573 0.010354 0.005881 0.009966 0.021664 0.013444 0.005995 0.009360
Golgi 0.006998 0.006099 0.001303 0.001076 0.003070 0.003628 0.000593 0.001416 0.005005 0.004593 0.001165 0.001268
Lipid Particles 0.001773 0.001092 0.000581 0.000616 0.002683 0.000438 0.001248 0.000301 0.002235 0.000693 0.000711 0.000437
Mitochondria 0.015040 0.014767 0.001492 0.001657 0.008339 0.010958 0.000909 0.002118 0.011640 0.012445 0.001379 0.001918
Mitotic Spindle 0.002297 0.003256 0.006618 0.007907 0.002126 0.002904 0.004698 0.009699 0.002210 0.003041 0.006244 0.008922
None 0.001935 0.000364 0.000910 0.000287 0.000674 0.000591 0.000296 0.000182 0.001296 0.000502 0.000790 0.000227
Nuclear Periphery 0.000023 0.000025 0.000077 0.000089 0.000080 0.000016 0.000137 0.000053 0.000052 0.000019 0.000089 0.000069
Nuclear Periphery Foci 0.000109 0.000189 0.000283 0.000614 0.000808 0.000081 0.000889 0.000301 0.000464 0.000123 0.000401 0.000437
Nucleolus 0.000232 0.001168 0.000234 0.000265 0.001872 0.000069 0.000247 0.000226 0.001064 0.000498 0.000237 0.000243
Nucleus 0.006450 0.003767 0.023078 0.010468 0.019334 0.003238 0.026421 0.013362 0.012987 0.003445 0.023729 0.012107
Peroxisomes 0.013288 0.020587 0.012651 0.022601 0.034429 0.012127 0.016372 0.016569 0.024013 0.015429 0.013376 0.019185
Vacuole 0.012804 0.017656 0.028094 0.025805 0.018157 0.010059 0.060250 0.032703 0.015520 0.013024 0.034361 0.029711
Vacuole Periphery 0.001207 0.002015 0.000277 0.000404 0.001161 0.000982 0.000219 0.000601 0.001184 0.001385 0.000266 0.000515

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.80 -2.45 -2.81 3.37 -1.10 -1.31 -2.56 -0.67 0.91 2.39 -5.34 -2.92 -2.59 3.17 0.34
Bud Neck 8.04 4.72 5.02 -7.66 0.93 -2.65 1.46 1.50 10.87 -0.15 3.02 3.60 4.69 4.29 2.55
Bud Site -5.94 -3.83 -4.82 2.35 -2.37 -3.93 -2.36 -3.77 0.32 -1.89 -6.70 -4.74 -5.98 1.61 -2.54
Cell Periphery 0.71 3.12 3.83 6.84 6.80 -0.29 4.45 5.04 9.03 3.23 0.35 4.90 5.95 11.35 7.14
Cytoplasm -3.79 -4.79 -1.60 3.72 5.45 3.11 2.41 -0.06 -8.06 -4.87 0.71 -1.70 -1.16 -4.09 1.06
Cytoplasmic Foci 0.20 3.44 2.99 7.23 -2.11 5.13 5.01 4.98 -0.86 -0.35 4.53 6.37 5.71 4.74 -3.56
Eisosomes -0.25 3.04 3.64 3.56 2.66 2.76 2.37 5.43 5.21 5.93 1.75 4.89 6.44 5.84 5.56
Endoplasmic Reticulum -3.83 -7.64 -6.85 -3.48 -1.76 3.15 -2.42 2.25 -4.69 5.86 2.30 -1.64 0.07 -5.60 3.19
Endosome 1.34 2.93 2.61 5.55 -2.48 1.50 2.77 1.71 0.39 -2.37 1.98 3.76 3.02 3.86 -3.71
Golgi 0.33 2.20 2.30 8.11 1.24 -0.82 4.86 3.18 5.14 -3.67 0.31 2.95 2.90 9.34 -0.39
Lipid Particles 0.75 1.22 1.10 1.05 -0.53 4.02 1.26 4.14 0.50 4.65 2.98 2.50 3.26 1.00 2.44
Mitochondria 0.06 2.71 2.68 7.22 -0.23 -0.67 1.99 1.67 6.15 -2.22 -0.25 3.30 3.13 9.34 -1.28
Mitotic Spindle -1.64 -4.50 -4.63 -4.04 -0.68 -0.74 -2.10 -4.88 -5.29 -1.99 -1.36 -4.73 -6.71 -6.64 -1.88
None 0.90 0.59 0.93 0.42 2.53 0.24 1.58 2.99 0.90 1.12 0.89 0.57 1.21 0.94 2.98
Nuclear Periphery -0.24 -6.24 -7.06 -7.19 -2.24 2.11 -3.35 -0.25 -3.98 3.56 2.05 -4.21 -3.28 -7.56 1.07
Nuclear Periphery Foci -1.37 -4.57 -4.21 -3.42 -2.51 3.25 -2.13 1.66 -4.19 4.07 2.83 -1.03 -0.85 -5.16 0.16
Nucleolus -1.52 -0.42 -0.67 1.42 -0.41 1.31 1.14 1.16 -3.39 0.44 0.74 1.12 1.11 0.91 -0.08
Nucleus 1.36 -6.44 -3.55 -6.25 3.04 3.91 -2.27 0.52 -8.15 3.32 4.09 -4.48 -1.40 -10.24 4.30
Peroxisomes -2.14 0.22 -2.53 -0.47 -4.17 2.63 1.97 2.15 -2.15 0.26 1.85 2.27 1.17 -2.06 -3.18
Vacuole -1.61 -6.64 -7.18 -6.89 -2.14 1.99 -8.33 -5.83 -11.81 5.63 1.00 -9.29 -9.17 -13.54 0.66
Vacuole Periphery -1.51 2.63 2.16 3.78 -0.92 0.45 2.74 1.38 1.29 -1.36 -0.66 3.73 2.38 3.56 -1.48
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
Localization
Cell Percentages bud neck (18%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Nis1

Nis1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nis1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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