Standard name
Human Ortholog
Description Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.07 0 0 0 0 0 0
Cytoplasm 0.98 0.96 0.98 0.98 0.94 0.82 0.72 0.65 0.68 0.58 0.58 0.55 0.99 0.98 0.99 0.98 0.97 0.95 0.93 0.92 0.91 0.84 0.83 0.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.06 0 0 0 0 0 0.05
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.11 0 0 0.11 0.2 0.38 0.56 0.47 0.56 0.56 0.62 0.63 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 3 2 0 4 2 0 0 0 0 0 0 1 3 6
Bud 0 3 0 1 9 17 12 20 12 11 17 24 2 1 0 0 0 1 0 0 0 1 3 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 2 2 1 3
Bud Site 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 1 1 3 9 4 8 10 11 11 19 4 12 16 2 10 10 0 0 0 0 0 1
Cytoplasm 46 263 211 343 569 525 561 600 439 513 313 521 483 556 741 87 96 134 77 258 200 299 329 448
Endoplasmic Reticulum 0 4 1 0 2 6 7 14 9 7 7 18 4 6 4 7 5 8 0 1 4 12 13 28
Endosome 0 0 0 0 4 2 0 7 0 3 1 1 1 0 2 0 0 0 0 2 1 2 1 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 1 0 3 4
Mitochondria 5 8 9 37 118 245 436 432 363 497 337 596 0 0 1 4 2 3 1 6 4 10 12 16
Nucleus 0 1 0 0 3 0 2 7 0 2 1 5 2 0 2 2 2 1 0 0 0 0 0 2
Nuclear Periphery 0 1 0 0 0 0 2 6 0 3 4 1 0 0 0 0 0 0 0 0 0 0 1 1
Nucleolus 0 0 0 0 0 0 0 3 0 0 0 3 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Vac/Vac Membrane 0 1 0 2 2 5 3 28 22 43 15 23 4 2 2 2 0 1 0 4 1 22 19 27
Unique Cell Count 47 273 216 351 604 637 784 927 644 882 543 952 489 566 750 89 99 141 84 280 220 358 396 558
Labelled Cell Count 52 282 222 384 710 809 1028 1126 855 1092 710 1213 500 582 773 104 115 158 84 280 220 358 396 558


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.2 6.0 4.9 5.0 4.8 4.8 4.1 4.6 4.4 4.4 4.8 4.6 7.2 7.1 7.2 7.4 7.7 7.7 7.7 7.8 8.1
Std Deviation (1e-4) 0.5 1.1 0.6 0.8 0.9 1.0 0.9 1.0 0.9 0.8 0.9 0.8 0.9 0.9 0.9 1.3 1.3 1.2 1.1 1.4 1.7
Intensity Change (Log2) – – – 0.04 -0.02 -0.03 -0.25 -0.07 -0.14 -0.15 -0.03 -0.08 0.57 0.56 0.56 0.62 0.66 0.68 0.66 0.69 0.74

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 -2.0 -5.6 -8.1 -9.6 -8.7 -11.0 -10.8 -11.8 1.1 0.5 1.2 0 -0.4 -1.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.7 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.6 2.8 3.3 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.47 4.4665 4.0747 3.7315 3.3589 4.0435 2.9832 4.2948 3.7693 3.2 3.769 4.0637 1.2815 2.4381 2.2842 1.8956 1.943 1.9234
Actin 0.0005 0.0007 0.0008 0.0003 0.0001 0.0004 0.0215 0.0037 0.0009 0.0001 0.0011 0.0016 0.0056 0.0026 0.0014 0.004 0.0018 0.0033
Bud 0.0028 0.0037 0.0048 0.0007 0.0008 0.0034 0.0006 0.0008 0.0008 0.0009 0.0002 0.0004 0.0003 0.0001 0.0012 0.001 0.0006 0.0001
Bud Neck 0.0012 0.0004 0.0004 0.0017 0.0005 0.001 0.0012 0.0002 0.0014 0.0006 0.0004 0.0006 0.0008 0.0008 0.0003 0.0006 0.0009 0.0009
Bud Periphery 0.0013 0.0019 0.0019 0.0004 0.001 0.0008 0.0005 0.0005 0.0009 0.0005 0.0001 0.0005 0.0002 0 0.001 0.0053 0.0006 0.0001
Bud Site 0.0117 0.0073 0.0069 0.0021 0.0002 0.0005 0.0061 0.0024 0.0047 0.0011 0.0008 0.0002 0.0044 0.0048 0.0048 0.0008 0.0017 0.0006
Cell Periphery 0.0004 0.0003 0.0002 0.0001 0.0001 0.0001 0.0005 0.0002 0.0004 0.0001 0.0001 0.0001 0.0002 0.0001 0.0003 0.0002 0.0002 0
Cytoplasm 0.8073 0.8693 0.851 0.8464 0.7691 0.8261 0.7708 0.9056 0.8614 0.8558 0.7397 0.87 0.8079 0.9321 0.918 0.7805 0.7046 0.8692
Cytoplasmic Foci 0.0272 0.0237 0.0231 0.0314 0.0327 0.0312 0.0325 0.019 0.0162 0.0314 0.0259 0.0176 0.0518 0.0129 0.0125 0.0247 0.0279 0.0478
Eisosomes 0.0001 0 0 0 0 0 0.0003 0 0.0001 0 0.0001 0 0 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0094 0.0032 0.0021 0.0027 0.0051 0.0046 0.0051 0.0021 0.004 0.0025 0.003 0.0025 0.0049 0.0022 0.0018 0.0067 0.0011 0.0023
Endosome 0.0303 0.0268 0.0263 0.0486 0.0381 0.04 0.0275 0.0183 0.018 0.036 0.0475 0.0166 0.0333 0.0093 0.0198 0.0597 0.0568 0.0343
Golgi 0.0026 0.002 0.0016 0.0012 0.0015 0.0015 0.0084 0.0029 0.0018 0.0011 0.0023 0.0029 0.0071 0.0008 0.0011 0.01 0.0624 0.0096
Lipid Particles 0.001 0.0001 0.0001 0.0002 0.0001 0.0002 0.0043 0.0001 0.0004 0.0002 0.003 0.0017 0.0048 0.0001 0.0002 0.0298 0.0297 0.0047
Mitochondria 0.0022 0.001 0.0017 0.0008 0.0044 0.0017 0.0033 0.0006 0.0027 0.0005 0.0009 0.0034 0.0019 0.0079 0.0041 0.0197 0.0755 0.007
None 0.091 0.0482 0.0677 0.0409 0.1356 0.0761 0.1014 0.038 0.0784 0.0545 0.1399 0.0763 0.06 0.0229 0.0235 0.0365 0.0095 0.0063
Nuclear Periphery 0.0009 0.0007 0.0006 0.0012 0.001 0.0006 0.0008 0.0005 0.0009 0.0007 0.001 0.0002 0.0009 0.0004 0.0008 0.0022 0.0005 0.0004
Nucleolus 0.0005 0.0002 0.0006 0.0003 0.0001 0.0002 0.0002 0 0.0001 0.0001 0.0003 0 0.0004 0 0.0003 0.0002 0.0022 0.0001
Nucleus 0.0021 0.003 0.0028 0.0025 0.0021 0.0026 0.0009 0.0009 0.001 0.0012 0.0022 0.0005 0.0011 0.0005 0.0017 0.0013 0.0012 0.0006
Peroxisomes 0.0002 0.0002 0.0004 0.0003 0.0004 0.0002 0.0055 0.0002 0.0002 0.0002 0.0258 0.0021 0.0055 0.0002 0.0002 0.0052 0.0105 0.0072
Punctate Nuclear 0.0015 0.0007 0.0009 0.002 0.0005 0.0021 0.0041 0.0002 0.0003 0.0003 0.0016 0.0002 0.0031 0.0001 0.0003 0.0005 0.0005 0.0032
Vacuole 0.0049 0.0057 0.0051 0.0134 0.0053 0.0056 0.004 0.0032 0.0046 0.0107 0.0033 0.002 0.005 0.0019 0.0053 0.0083 0.0092 0.0016
Vacuole Periphery 0.0009 0.001 0.0009 0.0028 0.0014 0.0009 0.0006 0.0006 0.0007 0.0017 0.0007 0.0005 0.0008 0.0003 0.0011 0.0026 0.0024 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 43.0897 49.5252 37.7706 26.8912 41.9008 52.2943 45.9019 47.4099 37.7339 37.8811
Translational Efficiency 1.1119 0.8734 0.8852 1.1847 0.9828 0.9451 0.8864 1.008 0.9255 1.2247

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
224 1746 332 1276 1442 1326 2336 1197 1666 3072 2668 2473

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.64 773.31 944.56 925.05 732.12 838.03 919.57 898.79 735.01 801.25 922.68 912.34
Standard Deviation 95.50 120.43 95.42 119.81 122.92 120.38 114.51 121.06 119.83 124.60 112.61 121.13
Intensity Change Log 2 — 0.037171 0.325767 0.295656 — 0.194922 0.328879 0.295904 — 0.117060 0.327301 0.295778

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000159 0.000279 0.000254 0.000681 0.000142 0.000320 0.000088 0.000308 0.000144 0.000297 0.000108 0.000500
Bud Neck 0.007820 0.011489 0.001650 0.002782 0.007090 0.012590 0.003766 0.004443 0.007188 0.011964 0.003503 0.003586
Bud Site 0.004759 0.029069 0.007332 0.025572 0.008267 0.032430 0.012617 0.018426 0.007796 0.030520 0.011960 0.022113
Cell Periphery 0.000241 0.000117 0.000297 0.000094 0.000145 0.000150 0.000063 0.000173 0.000158 0.000131 0.000092 0.000133
Cytoplasm 0.521743 0.555906 0.466392 0.632029 0.510704 0.517356 0.773546 0.516162 0.512188 0.539266 0.735325 0.575946
Cytoplasmic Foci 0.295440 0.244534 0.085988 0.037105 0.250615 0.242467 0.033586 0.059916 0.256642 0.243642 0.040107 0.048146
Eisosomes 0.000219 0.000071 0.000119 0.000028 0.000102 0.000090 0.000011 0.000066 0.000117 0.000079 0.000025 0.000046
Endoplasmic Reticulum 0.001176 0.001657 0.002673 0.001088 0.003796 0.001176 0.001913 0.001188 0.003444 0.001449 0.002008 0.001136
Endosome 0.028237 0.029714 0.014100 0.005757 0.033074 0.043989 0.003644 0.016241 0.032423 0.035875 0.004946 0.010832
Golgi 0.003817 0.015014 0.000179 0.002975 0.007426 0.014857 0.000584 0.003404 0.006941 0.014947 0.000534 0.003183
Lipid Particles 0.009677 0.002995 0.004712 0.001016 0.009755 0.002492 0.000461 0.001952 0.009744 0.002778 0.000990 0.001469
Mitochondria 0.000411 0.004962 0.000109 0.001884 0.003567 0.003251 0.000312 0.005078 0.003142 0.004224 0.000287 0.003430
Mitotic Spindle 0.000206 0.001558 0.000271 0.030188 0.001844 0.000920 0.004659 0.011115 0.001624 0.001283 0.004113 0.020956
None 0.001627 0.001632 0.001150 0.004156 0.005145 0.000272 0.001979 0.005766 0.004672 0.001045 0.001876 0.004935
Nuclear Periphery 0.000219 0.000141 0.001078 0.000552 0.000368 0.000080 0.000272 0.000518 0.000348 0.000114 0.000372 0.000535
Nuclear Periphery Foci 0.000960 0.000441 0.005618 0.001722 0.000789 0.000188 0.000740 0.001174 0.000812 0.000332 0.001347 0.001457
Nucleolus 0.000513 0.000681 0.000805 0.000157 0.001237 0.000270 0.000190 0.000836 0.001140 0.000503 0.000266 0.000486
Nucleus 0.048873 0.014227 0.160505 0.048647 0.031822 0.007664 0.055045 0.062871 0.034115 0.011394 0.068168 0.055532
Peroxisomes 0.002532 0.003332 0.000608 0.000953 0.002487 0.003369 0.000355 0.001484 0.002493 0.003348 0.000387 0.001210
Vacuole 0.070195 0.075627 0.245807 0.200759 0.116410 0.109494 0.105497 0.285345 0.110197 0.090245 0.122957 0.241701
Vacuole Periphery 0.001179 0.006556 0.000351 0.001857 0.005214 0.006575 0.000671 0.003537 0.004671 0.006564 0.000631 0.002670

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.41 -2.95 -1.81 -1.06 -0.76 -4.34 2.82 -2.16 1.08 -3.30 -5.60 1.37 -2.48 -0.64 -2.80
Bud Neck -1.81 3.17 2.82 10.60 -2.64 -5.39 5.90 5.20 8.73 -0.64 -6.18 6.63 7.74 13.49 -0.01
Bud Site -14.81 -1.04 -4.69 6.66 -2.51 -13.01 -0.93 -3.37 7.26 -2.42 -17.85 -1.17 -4.60 9.78 -3.05
Cell Periphery 6.26 -0.78 9.28 7.95 4.60 -0.17 7.67 0.60 0.60 -2.91 2.41 6.20 4.58 2.33 -0.88
Cytoplasm -2.11 4.70 0.82 4.56 -4.97 -0.67 -25.17 0.55 1.13 22.25 -3.37 -21.59 0.68 4.27 23.21
Cytoplasmic Foci 4.09 17.58 23.19 43.00 10.06 1.15 42.33 36.12 32.96 -8.37 2.25 45.73 45.31 53.36 -1.05
Eisosomes 6.48 4.14 8.64 6.47 11.56 1.42 15.36 6.95 5.21 -12.65 5.22 15.13 12.34 7.91 -7.22
Endoplasmic Reticulum -1.15 -5.86 1.28 2.15 7.93 4.69 3.29 5.04 0.86 0.84 3.95 2.83 5.43 2.23 1.61
Endosome -0.42 4.21 7.68 17.29 11.20 -4.32 22.22 11.61 13.02 -6.72 -1.93 22.29 18.18 20.21 -4.16
Golgi -10.18 4.68 2.99 14.61 -1.39 -7.75 14.08 6.28 11.80 -2.73 -11.21 14.73 8.82 18.61 -2.69
Lipid Particles 4.88 3.43 6.48 7.13 9.27 8.33 11.12 9.48 2.59 -3.90 9.10 11.68 11.31 6.57 -1.29
Mitochondria -7.95 6.34 -0.77 6.13 -1.51 0.33 4.04 0.14 -0.12 -3.03 -1.32 4.09 1.28 3.27 -3.26
Mitotic Spindle -2.92 -1.16 -7.55 -6.97 -6.80 1.21 -2.87 -3.50 -4.21 -1.76 0.51 -3.01 -7.52 -8.10 -5.62
None -0.02 0.88 -1.40 -1.58 -3.03 4.13 2.80 0.63 -2.87 -1.68 3.42 2.86 1.02 -3.14 -2.38
Nuclear Periphery 2.17 -12.05 -14.80 -15.91 2.63 4.89 -1.10 -1.24 -5.09 -0.66 4.53 -3.60 -6.25 -13.35 -4.46
Nuclear Periphery Foci 2.92 -8.51 -2.98 -5.95 7.93 6.95 0.22 -1.17 -3.96 -1.30 4.59 -5.69 -3.16 -6.52 1.99
Nucleolus -0.98 -1.00 3.45 3.25 3.36 4.23 4.73 2.04 -1.76 -2.19 3.01 4.60 3.45 0.75 -1.47
Nucleus 7.43 -9.29 -4.05 -20.71 7.87 13.35 -14.66 -7.44 -16.24 3.02 13.56 -16.88 -11.79 -25.74 5.12
Peroxisomes -1.42 3.54 3.64 10.80 0.69 -1.59 4.47 2.66 7.46 -4.53 -1.85 5.01 3.82 12.78 -4.16
Vacuole -0.91 -15.40 -27.75 -30.84 -2.62 1.11 -5.29 -23.53 -23.84 -20.31 4.78 -10.47 -33.49 -39.17 -24.44
Vacuole Periphery -11.16 5.88 2.20 11.82 -1.62 -2.28 12.37 4.34 5.86 -3.43 -4.12 12.61 7.51 11.70 -3.43
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA
Localization
Cell Percentages cytoplasm (94%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Oca1

Oca1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Oca1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available