Standard name
Human Ortholog
Description Protein involved in recovery from cell cycle arrest; acts in response to pheromone; also involved in regulation of intra-S DNA damage checkpoint and autophagy; is essential for dephosphorylation of Atg13p; interacts with Far3p, Far7p, Far8p, Far9p, Far10p and with the phosphatases Pph21p, Pph22p and Pph3p; has similarity to the N- and C-termini of N. crassa HAM-2; similar to human Fam40A and Fam40B
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0.05 0 0.06 0
Bud 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.07 0 0 0.05 0 0.05 0 0 0 0 0 0.07 0.06 0.05 0.06 0.11 0.14 0 0 0 0.07 0 0.06
Cytoplasm 0.58 0.73 0.85 0.89 0.91 0.82 0.69 0.64 0.65 0.55 0.57 0.5 0.95 0.95 0.96 0.84 0.75 0.82 0.25 0.42 0.25 0.49 0.48 0.38
Endoplasmic Reticulum 0.39 0.21 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.07 0.07 0.49 0.32 0.19 0.14 0.16 0.34
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.16 0.15 0.11 0.31 0.37 0.45 0.54 0.59 0.59 0.66 0 0 0 0 0 0 0.09 0.1 0.36 0.15 0.11 0.09
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.07 0 0 0 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 8 1 1 2 0 0 0 0 0 0 0 0 1 1 0 13 11 6 9 5 7 3 12 10
Bud 2 2 8 7 3 9 11 17 5 8 7 9 3 2 12 3 2 7 1 1 0 0 2 2
Bud Neck 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 5 0 7 7 7 1 8 3
Bud Site 0 0 0 1 0 0 1 1 1 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 6 12 4 8 11 5 17 7 5 8 2 12 12 15 14 16 24 37 3 6 6 7 7 14
Cytoplasm 94 124 116 171 211 200 237 343 118 144 122 164 156 231 267 241 167 219 54 86 39 53 90 95
Endoplasmic Reticulum 63 35 6 1 1 1 7 4 2 5 5 6 2 6 1 35 16 18 106 66 31 14 30 85
Endosome 1 1 0 2 2 0 6 8 0 1 0 0 0 0 1 7 6 6 2 1 0 0 2 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 4 2 1 0 0 0
Mitochondria 1 5 22 28 26 75 126 244 98 153 126 216 3 3 4 10 6 5 18 19 57 16 21 21
Nucleus 1 0 0 1 0 2 4 4 2 0 3 0 1 0 0 2 1 1 0 0 0 0 1 1
Nuclear Periphery 1 1 0 0 0 0 2 0 0 0 1 0 0 0 1 0 1 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 2 2 2 0 0 1 2 1 0 0 3 2 1 0 0 0 0 0 0
Vac/Vac Membrane 2 1 1 1 5 3 11 20 5 14 4 12 0 1 3 11 16 8 6 8 5 5 8 10
Unique Cell Count 163 170 137 192 232 245 342 537 182 261 214 329 164 242 278 288 223 267 217 206 161 109 189 251
Labelled Cell Count 179 182 158 222 259 298 424 652 236 335 271 421 179 260 305 343 259 309 217 206 161 109 189 251


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 4.9 4.1 4.3 4.7 4.3 4.1 4.0 3.7 3.7 3.7 3.4 5.5 5.6 5.0 6.5 7.0 7.0 5.9 6.1 6.1
Std Deviation (1e-4) 0.6 0.6 1.1 1.4 1.6 1.8 1.3 1.5 1.5 1.5 1.5 1.4 1.1 0.9 1.1 1.2 1.2 1.4 1.2 2.2 1.5
Intensity Change (Log2) – – – 0.06 0.2 0.06 -0.0 -0.03 -0.17 -0.15 -0.14 -0.26 0.44 0.45 0.29 0.68 0.78 0.78 0.52 0.57 0.58

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 -1.8 0 -0.7 0 0 -1.6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 1.7 1.4 1.0 1.2 2.7 3.4
Cytoplasm 1.2 1.8 -0.8 -3.5 -4.7 -4.0 -5.9 -5.4 -7.0 3.1 3.6 4.1 -0.3 -2.2 -0.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.5 1.1 1.0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -4.5 -5.6 -5.8 -4.6 -4.6 -5.4
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 2.3 0 0 0 0 0 0 2.8 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.0356 1.8531 2.0287 1.9027 2.4559 1.7196 2.0695 2.2248 2.2294 1.8189 1.5985 1.9976 1.8296 2.3356 1.9628 2.3389 2.0115 2.2469
Actin 0.0417 0.0044 0.0336 0.0108 0.0354 0.0072 0.0292 0.0127 0.0225 0.0513 0.0363 0.0106 0.018 0.0012 0.0022 0.0136 0.0373 0.0055
Bud 0.0026 0.0017 0.0032 0.0013 0.0006 0.0013 0.0011 0.0005 0.0026 0.0028 0.0005 0.0008 0.0004 0.0009 0.0005 0.0053 0.0002 0.0002
Bud Neck 0.0065 0.0011 0.0076 0.005 0.0043 0.007 0.0067 0.0004 0.0019 0.0016 0.0012 0.0042 0.0007 0.0014 0.0023 0.0033 0.0008 0.0022
Bud Periphery 0.0091 0.0018 0.0082 0.0036 0.0013 0.0035 0.0025 0.0011 0.0042 0.0072 0.001 0.0029 0.0012 0.0022 0.0011 0.01 0.0005 0.0006
Bud Site 0.0072 0.0368 0.0259 0.0085 0.0017 0.0008 0.0131 0.0111 0.0105 0.0065 0.0017 0.0012 0.0028 0.0125 0.0042 0.0045 0.0003 0.0006
Cell Periphery 0.0029 0.0031 0.0044 0.0013 0.0025 0.0022 0.0029 0.0024 0.0013 0.0007 0.0012 0.001 0.0033 0.004 0.0032 0.0022 0.0012 0.0013
Cytoplasm 0.4682 0.5994 0.5936 0.4866 0.5418 0.6661 0.4228 0.5552 0.5336 0.5279 0.5085 0.5883 0.3555 0.558 0.5272 0.406 0.5599 0.5247
Cytoplasmic Foci 0.0336 0.0182 0.0301 0.0155 0.0222 0.0259 0.0575 0.0106 0.032 0.0296 0.0303 0.0209 0.018 0.0122 0.0184 0.0128 0.0171 0.0251
Eisosomes 0.0006 0.0002 0.0006 0.0004 0.0004 0.0002 0.0024 0.0004 0.0003 0.0005 0.0004 0.0002 0.0008 0.0003 0.0005 0.0005 0.0003 0.0002
Endoplasmic Reticulum 0.0441 0.0257 0.0267 0.0328 0.0252 0.0355 0.0494 0.0231 0.0269 0.0281 0.0298 0.0251 0.0186 0.0125 0.024 0.0197 0.0107 0.0195
Endosome 0.03 0.0116 0.0199 0.0188 0.052 0.0138 0.0407 0.0055 0.0252 0.0134 0.0581 0.0133 0.0084 0.0057 0.0134 0.0056 0.0029 0.006
Golgi 0.0063 0.0029 0.0123 0.008 0.0193 0.0049 0.0156 0.004 0.0123 0.0072 0.0344 0.005 0.003 0.0006 0.0022 0.0009 0.0017 0.0018
Lipid Particles 0.0121 0.0035 0.0147 0.0394 0.0288 0.0098 0.0219 0.0026 0.0094 0.003 0.0098 0.003 0.0078 0.001 0.0038 0.0012 0.0012 0.005
Mitochondria 0.0147 0.001 0.014 0.0421 0.0153 0.0109 0.0095 0.0017 0.0055 0.0147 0.0249 0.0025 0.0027 0.0003 0.0014 0.0006 0.001 0.0021
None 0.2421 0.2757 0.1798 0.2976 0.1934 0.1896 0.2395 0.3627 0.2816 0.2707 0.2468 0.3095 0.5203 0.3821 0.3867 0.504 0.3562 0.3866
Nuclear Periphery 0.0335 0.002 0.0026 0.0089 0.0161 0.0081 0.0121 0.0008 0.006 0.0023 0.004 0.0038 0.0018 0.0007 0.0017 0.002 0.0005 0.0012
Nucleolus 0.0009 0.0005 0.0008 0.0023 0.0019 0.0004 0.0026 0.0002 0.0003 0.0003 0.0002 0.0002 0.0011 0.0002 0.0003 0.0004 0.0001 0.0002
Nucleus 0.0082 0.0023 0.0033 0.0022 0.0168 0.0051 0.0084 0.0009 0.0066 0.0015 0.0012 0.0013 0.0015 0.0011 0.0014 0.0019 0.0005 0.0011
Peroxisomes 0.0052 0.0012 0.0092 0.0063 0.0043 0.0016 0.0284 0.0017 0.0115 0.0256 0.0036 0.0026 0.0289 0.0001 0.0006 0.0003 0.0021 0.0117
Punctate Nuclear 0.0212 0.0023 0.004 0.0023 0.0101 0.0017 0.0272 0.0005 0.0028 0.0018 0.0017 0.0011 0.0028 0.0005 0.0011 0.0022 0.0046 0.0025
Vacuole 0.0058 0.004 0.0049 0.0041 0.0042 0.0032 0.005 0.0018 0.0024 0.0027 0.0029 0.0019 0.0022 0.0023 0.0033 0.0026 0.0009 0.0014
Vacuole Periphery 0.0035 0.0004 0.0006 0.0024 0.0025 0.0012 0.0015 0.0001 0.0008 0.0006 0.0013 0.0006 0.0002 0.0001 0.0003 0.0003 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.5057 6.5483 8.951 13.214 10.4972 11.1744 10.9768 13.1709 12.277 14.8603
Translational Efficiency 0.478 0.7478 0.8577 0.6859 0.69 0.9243 0.5946 0.4989 0.6232 0.5577

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
493 1223 1765 149 1400 1913 196 75 1893 3136 1961 224

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 703.57 830.02 1068.77 924.48 632.67 813.45 977.18 940.13 651.13 819.91 1059.62 929.72
Standard Deviation 76.94 109.33 123.72 114.27 92.51 100.95 101.37 122.57 94.01 104.61 124.73 117.34
Intensity Change Log 2 — 0.238452 0.603186 0.393948 — 0.362600 0.627171 0.571407 — 0.298566 0.614592 0.480695

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001227 0.002781 0.000447 0.000669 0.001019 0.001309 0.000271 0.000618 0.001073 0.001883 0.000430 0.000652
Bud Neck 0.041117 0.024721 0.002931 0.007906 0.016753 0.038186 0.004412 0.004208 0.023098 0.032935 0.003079 0.006668
Bud Site 0.022859 0.029293 0.011106 0.061977 0.008227 0.028469 0.003748 0.013566 0.012037 0.028791 0.010370 0.045768
Cell Periphery 0.002076 0.000640 0.000285 0.000213 0.000321 0.000701 0.000405 0.000536 0.000778 0.000677 0.000297 0.000321
Cytoplasm 0.356693 0.314519 0.647024 0.363464 0.317110 0.322003 0.347285 0.342522 0.327419 0.319084 0.617065 0.356452
Cytoplasmic Foci 0.235334 0.338037 0.047930 0.068738 0.326975 0.279657 0.079128 0.127346 0.303109 0.302424 0.051048 0.088361
Eisosomes 0.002347 0.001208 0.000042 0.000119 0.000597 0.001273 0.000197 0.000258 0.001053 0.001247 0.000058 0.000166
Endoplasmic Reticulum 0.040033 0.026584 0.006876 0.002178 0.024106 0.022866 0.005534 0.009574 0.028254 0.024316 0.006742 0.004654
Endosome 0.046503 0.043366 0.002987 0.015324 0.044131 0.054046 0.011824 0.010335 0.044749 0.049881 0.003870 0.013653
Golgi 0.026778 0.026010 0.000217 0.002349 0.018952 0.027555 0.000125 0.000457 0.020990 0.026953 0.000208 0.001715
Lipid Particles 0.076707 0.031801 0.002457 0.003509 0.069255 0.036928 0.007194 0.007378 0.071196 0.034928 0.002930 0.004804
Mitochondria 0.016681 0.011181 0.000172 0.000401 0.015368 0.017457 0.000134 0.021215 0.015710 0.015010 0.000168 0.007370
Mitotic Spindle 0.005795 0.001855 0.001566 0.018643 0.000523 0.002830 0.000164 0.013465 0.001896 0.002450 0.001426 0.016910
None 0.000794 0.000548 0.001909 0.000943 0.006541 0.000639 0.001966 0.000843 0.005044 0.000604 0.001914 0.000910
Nuclear Periphery 0.001304 0.000555 0.000785 0.001397 0.004101 0.000435 0.001974 0.007469 0.003373 0.000482 0.000904 0.003430
Nuclear Periphery Foci 0.001096 0.001673 0.012599 0.005360 0.002797 0.000861 0.007716 0.017957 0.002354 0.001178 0.012111 0.009578
Nucleolus 0.000432 0.000418 0.000138 0.000262 0.002997 0.000891 0.000533 0.000377 0.002329 0.000706 0.000177 0.000300
Nucleus 0.033795 0.034176 0.176533 0.048415 0.058762 0.033460 0.198549 0.067956 0.052260 0.033739 0.178734 0.054958
Peroxisomes 0.010842 0.012957 0.000283 0.001707 0.007925 0.011082 0.000640 0.003663 0.008685 0.011813 0.000319 0.002362
Vacuole 0.072630 0.092428 0.083510 0.395727 0.067868 0.113759 0.328016 0.349326 0.069108 0.105440 0.107948 0.380191
Vacuole Periphery 0.004955 0.005252 0.000204 0.000700 0.005671 0.005592 0.000184 0.000930 0.005485 0.005460 0.000202 0.000777

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.19 2.33 2.03 5.74 -0.61 -0.74 1.83 0.84 3.65 -2.89 -2.44 2.03 1.56 7.05 -1.48
Bud Neck 4.09 10.32 9.16 9.02 -1.50 -9.93 9.41 9.28 18.01 0.18 -5.34 14.63 11.23 17.83 -1.52
Bud Site -1.87 3.75 -0.71 -0.07 -1.97 -10.91 5.27 -0.88 3.59 -1.85 -10.73 1.12 -1.82 0.74 -2.05
Cell Periphery 6.18 7.80 8.32 8.11 4.44 -8.93 -1.23 -1.99 2.75 -1.41 1.46 7.26 7.21 9.23 0.90
Cytoplasm 3.41 -22.70 2.52 0.94 13.60 -0.65 1.15 0.90 1.08 0.21 1.15 -33.87 1.87 1.50 15.11
Cytoplasmic Foci -10.81 24.53 19.85 35.17 -0.19 6.86 33.35 15.00 12.09 -2.44 0.18 52.93 30.73 32.71 -2.58
Eisosomes 4.21 11.24 10.88 6.07 -4.78 -6.82 8.25 6.46 11.31 -1.23 -1.75 14.95 13.25 12.30 -6.39
Endoplasmic Reticulum 2.44 6.49 7.42 10.94 9.47 0.42 8.16 4.85 4.72 -0.76 1.59 10.33 10.83 12.14 2.73
Endosome 0.76 11.47 8.97 12.09 -1.95 -3.67 14.98 15.04 20.96 1.23 -2.25 22.88 15.87 20.85 -2.64
Golgi 0.33 12.31 11.53 15.62 -0.89 -5.66 18.66 18.28 23.59 -2.00 -4.57 22.17 19.66 26.16 -1.02
Lipid Particles 7.70 13.18 13.15 17.84 -0.05 9.57 20.35 18.97 14.80 0.05 12.55 25.55 24.73 24.85 -1.69
Mitochondria 2.37 8.18 8.16 9.17 -0.32 -1.09 10.28 0.19 0.36 -1.01 0.46 12.80 2.56 2.45 -1.01
Mitotic Spindle 1.40 1.33 -1.37 -2.07 -2.04 -3.66 2.60 -1.64 -1.25 -1.69 -0.65 0.03 -2.45 -2.35 -2.46
None 1.13 -2.93 -2.35 -2.83 -0.67 5.96 4.83 5.39 -0.91 1.07 6.03 4.30 3.98 -2.92 -0.08
Nuclear Periphery 1.72 1.02 0.10 -2.33 -1.35 4.91 2.51 -0.22 -1.12 -0.71 5.12 4.20 0.57 -1.47 -1.10
Nuclear Periphery Foci -2.27 -16.84 -2.88 -2.27 7.12 7.86 -4.17 -1.75 -2.07 -0.97 5.79 -15.23 -2.25 -2.79 2.33
Nucleolus 0.15 9.19 3.84 3.52 -1.60 5.11 6.55 5.86 1.79 0.19 5.40 7.50 6.90 3.35 -1.22
Nucleus -0.19 -34.43 -3.83 -3.82 12.38 9.37 -9.06 -1.21 -2.84 5.33 8.66 -31.65 -2.29 -4.78 12.97
Peroxisomes -1.69 12.46 10.98 12.51 -2.62 -4.54 15.38 1.89 3.22 -1.28 -4.96 20.09 7.63 10.79 -1.96
Vacuole -3.54 -5.34 -16.13 -15.49 -15.11 -11.07 -15.95 -9.98 -8.74 -0.96 -11.18 -13.57 -19.08 -17.40 -15.97
Vacuole Periphery -0.47 11.11 10.60 11.58 -0.76 0.11 12.32 7.85 9.25 -0.92 0.04 15.13 13.12 17.55 -1.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in recovery from cell cycle arrest; acts in response to pheromone; also involved in regulation of intra-S DNA damage checkpoint and autophagy; is essential for dephosphorylation of Atg13p; interacts with Far3p, Far7p, Far8p, Far9p, Far10p and with the phosphatases Pph21p, Pph22p and Pph3p; has similarity to the N- and C-termini of N. crassa HAM-2; similar to human Fam40A and Fam40B
Localization
Cell Percentages ER (30%), cytoplasm (10%), mixed (49%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Far11

Far11


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Far11-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available