Standard name
Human Ortholog
Description Protein of unknown function; required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.06 0.08 0.12 0.15 0.12 – 0.06 0.09 0.07 0.07 0.05 0.13 0.18 0.15 0.12 0.13 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.13 0 0.08 0 0.55 0.17 – 0.48 0.38 0.59 0.57 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.96 0.9 0.91 0.83 0.8 0.61 0.73 – 0.73 0.71 0.68 0.67 0.93 0.82 0.76 0.71 0.73 0.68 0.9 0.85 0.78 0.78 0.67 0.55
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.07 0 0.05 0.07 0 0.06 – 0 0 0 0 0 0.06 0.07 0.15 0.16 0.23 0 0.07 0.15 0.13 0.21 0.25
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Bud 0 0 0 0 0 2 0 – 2 5 10 4 0 0 0 0 0 1 2 1 0 3 5 7
Bud Neck 0 0 1 1 0 0 0 – 0 0 2 0 0 0 0 0 0 0 0 0 0 1 1 1
Bud Site 0 0 0 0 0 7 2 – 6 2 15 12 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9 3 8 17 39 38 49 – 24 38 23 21 21 74 112 41 28 29 2 1 5 5 4 8
Endoplasmic Reticulum 0 1 0 0 1 1 0 – 0 0 0 0 0 0 0 6 7 10 0 0 0 3 0 1
Endosome 1 0 1 6 5 0 7 – 1 3 0 1 0 4 6 7 5 8 1 2 0 1 4 9
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 1 3 0 1 1 2 0
Mitochondria 15 12 1 16 10 140 68 – 178 155 182 179 4 5 1 10 9 9 3 0 0 2 6 14
Nucleus 292 82 129 174 259 156 285 – 271 290 212 212 354 468 467 189 165 151 278 83 126 231 304 280
Nuclear Periphery 0 1 0 1 2 2 1 – 3 1 2 2 0 0 0 1 2 0 0 0 0 0 1 3
Nucleolus 0 0 0 1 0 2 0 – 0 3 0 1 0 2 1 0 0 1 0 0 0 1 13 23
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 0 3 2 0 3 – 7 4 2 2 0 1 1 0 1 0 0 0 0 2 12 20
Vac/Vac Membrane 2 6 6 10 22 7 24 – 10 13 6 2 7 32 45 40 37 52 10 7 24 37 97 130
Unique Cell Count 305 91 141 209 322 256 393 373 410 311 315 382 570 618 267 227 223 308 98 162 296 458 515
Labelled Cell Count 319 105 147 229 340 355 439 502 514 454 436 386 586 634 295 254 262 308 98 162 296 458 515


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 4.8 5.3 5.1 5.7 3.8 4.9 – 4.1 4.5 4.0 4.0 5.7 5.7 5.9 6.4 7.0 6.7 5.2 5.3 5.5
Std Deviation (1e-4) 0.7 0.8 1.1 1.4 1.4 1.2 1.6 – 1.2 1.7 1.6 0.9 1.2 1.0 1.4 1.4 1.3 1.7 1.5 1.4 1.3
Intensity Change (Log2) – – – -0.06 0.12 -0.49 -0.11 – -0.36 -0.24 -0.39 -0.41 0.11 0.1 0.16 0.27 0.41 0.35 -0.02 0.01 0.05

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 3.3 3.5 4.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.1723 -0.0395 -0.2645 -0.3076 -0.5288 -0.1971 0.9531 1.4172 1.1154 1.0931 0.5589 1.2513 2.6103 2.4605 2.4054 2.4804 2.1104 2.2968
Actin 0.0025 0 0.0001 0 0 0 0.0006 0.0001 0.0012 0 0 0.0003 0.0309 0.0001 0.0332 0.0002 0.0036 0.001
Bud 0 0 0 0 0 0 0.0002 0.0001 0.0001 0 0 0 0.0003 0.0001 0.0014 0 0 0.0001
Bud Neck 0.001 0.0002 0.0002 0.0002 0.0005 0.0008 0.003 0.0008 0.0002 0.0004 0.0002 0.0009 0.0044 0.0003 0.006 0.0002 0.0003 0.0011
Bud Periphery 0.0001 0 0 0 0.0001 0 0.0008 0 0.0001 0 0 0 0.0006 0.0002 0.0023 0 0 0.0001
Bud Site 0.0002 0.0001 0 0 0.0001 0 0.0024 0.0006 0.0002 0 0 0.0001 0.0016 0.0005 0.0212 0.0001 0.0004 0.0004
Cell Periphery 0 0 0 0 0 0 0.0002 0 0 0 0 0 0.0002 0 0.0004 0 0 0
Cytoplasm 0.007 0.0091 0.0039 0.0032 0.0025 0.0037 0.0045 0.0186 0.003 0.0034 0.0005 0.0028 0.0142 0.0277 0.0119 0.011 0.0076 0.0106
Cytoplasmic Foci 0.0029 0.0002 0.0002 0 0 0.0002 0.0076 0.0004 0.0027 0.0001 0 0.0002 0.0072 0.0001 0.0091 0.0001 0.0048 0.0005
Eisosomes 0 0 0 0 0 0 0 0 0 0 0 0 0.0003 0 0.0003 0 0.0001 0
Endoplasmic Reticulum 0.0007 0.0005 0.0006 0.0002 0.0001 0.0002 0.0008 0.0012 0.0002 0.0001 0 0.0003 0.0036 0.0015 0.0017 0.0005 0.0002 0.0014
Endosome 0.003 0.0004 0.0005 0.0003 0.0002 0.0004 0.0095 0.0011 0.003 0.0002 0 0.0006 0.0076 0.0006 0.0033 0.0003 0.0013 0.0009
Golgi 0.0004 0 0 0 0 0 0.0022 0 0.0009 0 0 0.0001 0.0031 0 0.0038 0 0.0021 0.0002
Lipid Particles 0.0016 0 0.0001 0 0 0.0001 0.0019 0 0.0013 0 0 0.0001 0.0074 0 0.0068 0 0.011 0.0003
Mitochondria 0.0004 0.0002 0.0003 0.0003 0.0004 0.0001 0.0009 0.0002 0.0004 0.0001 0.0002 0.0003 0.0018 0.0005 0.0021 0.0004 0.001 0.0077
None 0.0103 0.004 0.0174 0.0035 0.0006 0.0058 0.0102 0.013 0.0102 0.0058 0.0002 0.0014 0.0096 0.0078 0.0054 0.0047 0.0661 0.0107
Nuclear Periphery 0.0218 0.0218 0.0344 0.0208 0.0079 0.0124 0.0058 0.015 0.0097 0.0045 0.0026 0.004 0.0081 0.0129 0.0044 0.0173 0.0025 0.0033
Nucleolus 0.0063 0.0059 0.005 0.0041 0.0084 0.0098 0.0044 0.0038 0.003 0.006 0.0118 0.009 0.0078 0.009 0.005 0.0057 0.006 0.0077
Nucleus 0.9267 0.937 0.9249 0.9582 0.9684 0.9532 0.9307 0.9373 0.9567 0.964 0.9798 0.9716 0.8789 0.9341 0.8573 0.9521 0.8702 0.9429
Peroxisomes 0.0015 0 0 0 0 0 0.0023 0 0.0012 0 0 0.0001 0.0064 0 0.02 0 0.0155 0.0005
Punctate Nuclear 0.0127 0.0199 0.0117 0.0084 0.0105 0.0132 0.0107 0.0039 0.0056 0.0151 0.0044 0.0078 0.0025 0.0027 0.0033 0.007 0.0069 0.0101
Vacuole 0.0007 0.0004 0.0003 0.0003 0.0002 0.0001 0.0011 0.0033 0.0002 0.0002 0 0.0002 0.0027 0.0014 0.0008 0.0002 0.0001 0.0004
Vacuole Periphery 0.0003 0.0002 0.0004 0.0003 0.0001 0.0001 0.0003 0.0007 0.0001 0 0 0.0001 0.0009 0.0004 0.0002 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.3414 3.7792 4.2065 4.5578 5.4813 4.2253 7.1647 6.4476 8.0774 5.1695
Translational Efficiency 1.2963 1.5288 1.6753 2.4068 2.316 2.3074 0.9805 1.6341 1.2013 2.3524

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1726 842 293 249 1740 98 328 1546 3466 940 621 1795

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 742.04 765.53 959.87 949.97 689.32 838.72 952.20 890.05 715.57 773.16 955.82 898.36
Standard Deviation 86.80 115.40 97.18 119.99 87.71 95.09 110.46 105.19 91.16 115.64 104.47 109.35
Intensity Change Log 2 — 0.044962 0.371342 0.356385 — 0.283015 0.466091 0.368713 — 0.164512 0.417749 0.362335

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000057 0.000269 0.000617 0.000646 0.000077 0.000148 0.000725 0.000534 0.000067 0.000256 0.000674 0.000549
Bud Neck 0.001719 0.003308 0.004663 0.003509 0.001371 0.000766 0.002024 0.011269 0.001544 0.003043 0.003269 0.010193
Bud Site 0.000722 0.001282 0.000928 0.003604 0.000629 0.004412 0.000816 0.009502 0.000676 0.001608 0.000869 0.008684
Cell Periphery 0.000089 0.000216 0.000077 0.000186 0.000133 0.000073 0.000085 0.000142 0.000111 0.000201 0.000081 0.000148
Cytoplasm 0.048674 0.081997 0.007093 0.103175 0.074039 0.011306 0.017224 0.052717 0.061408 0.074627 0.012444 0.059716
Cytoplasmic Foci 0.007140 0.013294 0.000202 0.004820 0.008416 0.005963 0.000851 0.000708 0.007781 0.012529 0.000545 0.001279
Eisosomes 0.000014 0.000030 0.000032 0.000061 0.000016 0.000029 0.000040 0.000023 0.000015 0.000030 0.000036 0.000028
Endoplasmic Reticulum 0.001732 0.004556 0.008936 0.011907 0.001113 0.001900 0.009639 0.006288 0.001421 0.004279 0.009307 0.007068
Endosome 0.000492 0.001540 0.000591 0.004814 0.000650 0.001145 0.000544 0.001597 0.000571 0.001499 0.000566 0.002043
Golgi 0.000203 0.000825 0.000053 0.001373 0.000769 0.000448 0.000053 0.000696 0.000487 0.000786 0.000053 0.000790
Lipid Particles 0.000995 0.001872 0.000458 0.002074 0.001695 0.007429 0.000701 0.000360 0.001346 0.002451 0.000587 0.000597
Mitochondria 0.000828 0.002007 0.000629 0.000799 0.002096 0.003253 0.000547 0.006244 0.001465 0.002137 0.000586 0.005489
Mitotic Spindle 0.000959 0.001126 0.000125 0.010180 0.000991 0.000648 0.000264 0.015256 0.000975 0.001076 0.000199 0.014552
None 0.003172 0.013313 0.001826 0.014555 0.007900 0.005928 0.003248 0.005783 0.005545 0.012543 0.002577 0.007000
Nuclear Periphery 0.002097 0.001372 0.001019 0.002202 0.001115 0.000582 0.000925 0.001969 0.001604 0.001290 0.000969 0.002001
Nuclear Periphery Foci 0.000327 0.000577 0.000333 0.003255 0.000313 0.001226 0.000534 0.000671 0.000320 0.000644 0.000439 0.001029
Nucleolus 0.001895 0.006356 0.001628 0.001270 0.002606 0.005236 0.001830 0.001466 0.002252 0.006239 0.001735 0.001439
Nucleus 0.926308 0.858832 0.963841 0.762524 0.892984 0.943059 0.949415 0.869932 0.909579 0.867613 0.956222 0.855033
Peroxisomes 0.000601 0.002561 0.000133 0.000231 0.001416 0.002970 0.000188 0.000207 0.001010 0.002604 0.000162 0.000210
Vacuole 0.001849 0.004332 0.006715 0.063792 0.001526 0.003060 0.010253 0.012856 0.001687 0.004200 0.008583 0.019922
Vacuole Periphery 0.000129 0.000333 0.000102 0.005020 0.000147 0.000419 0.000093 0.001781 0.000138 0.000342 0.000097 0.002231

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.45 -9.86 -11.40 -7.35 -3.39 -1.43 -10.07 -10.40 -6.23 3.30 -3.48 -13.97 -14.07 -5.60 2.22
Bud Neck -2.38 -7.45 -6.07 -3.80 -1.24 1.44 -2.95 -12.07 -11.97 -9.64 -2.65 -7.29 -12.65 -9.29 -8.73
Bud Site -1.82 -2.12 -5.40 -4.66 -4.61 -0.89 -1.63 -5.55 -0.75 -5.16 -1.82 -2.58 -6.03 -4.80 -5.53
Cell Periphery -4.32 0.04 -3.33 1.62 -3.38 1.20 0.99 0.21 -1.36 -1.85 -3.11 0.91 -1.18 2.66 -3.38
Cytoplasm -5.27 15.16 -1.88 1.72 -6.95 9.06 10.57 4.28 -6.47 -7.37 -2.34 15.89 1.68 3.25 -12.21
Cytoplasmic Foci -2.76 7.84 4.01 4.94 -2.99 0.62 7.11 7.75 1.66 1.18 -2.40 10.42 10.13 6.20 -1.26
Eisosomes -5.76 -6.42 -11.97 -8.86 -7.23 -2.09 -7.31 -9.90 0.01 3.98 -6.12 -9.66 -14.97 -3.09 1.59
Endoplasmic Reticulum -4.28 -9.74 -11.18 -8.31 -3.97 -1.66 -13.26 -19.95 -9.43 4.90 -4.97 -16.24 -21.04 -7.03 3.38
Endosome -4.07 -1.80 -4.28 -2.42 -3.84 -0.73 -0.39 -2.54 -0.16 -2.97 -3.81 -1.38 -4.86 -0.05 -4.40
Golgi -2.03 1.27 -0.99 0.86 -1.64 0.66 2.23 1.05 0.15 -1.62 -0.96 2.53 0.41 1.27 -1.93
Lipid Particles -3.60 3.45 -2.32 -0.20 -3.44 -1.09 2.47 4.71 1.32 2.75 -2.00 3.59 4.11 3.15 0.33
Mitochondria -1.72 0.71 -1.35 1.33 -3.55 -0.55 2.12 -2.05 -0.40 -4.45 -0.96 2.24 -3.01 -1.74 -4.50
Mitotic Spindle -0.21 1.27 -2.95 -2.90 -3.15 0.64 1.14 -6.79 -6.97 -7.11 -0.14 1.68 -7.36 -7.19 -7.73
None -6.20 2.13 -2.03 1.85 -2.63 0.63 5.07 2.56 0.23 -3.07 -4.69 5.31 -0.22 4.47 -4.91
Nuclear Periphery 1.28 2.08 -3.91 -4.82 -8.93 2.39 -0.39 -9.71 -10.64 -11.54 0.73 1.81 -6.52 -4.37 -13.26
Nuclear Periphery Foci -1.87 -0.49 -3.51 -3.08 -3.43 -0.84 -3.21 -2.73 0.45 0.11 -2.30 -2.61 -4.08 -1.46 -2.43
Nucleolus -4.41 0.72 1.36 5.40 0.84 -1.12 2.61 1.94 1.52 -0.10 -4.49 2.16 1.69 5.18 0.06
Nucleus 7.62 -4.83 9.57 5.19 11.06 -2.65 -5.24 5.18 4.70 9.44 5.27 -6.83 10.85 2.68 15.17
Peroxisomes -2.28 2.77 2.22 2.81 -2.48 -0.95 2.30 2.40 1.79 1.59 -2.01 3.10 3.13 3.20 0.39
Vacuole -3.39 -4.46 -9.19 -8.94 -7.97 -1.08 -5.51 -12.45 -9.38 -1.95 -3.66 -7.08 -14.79 -13.17 -6.63
Vacuole Periphery -4.18 0.51 -1.22 -1.04 -1.23 -1.12 1.28 -2.37 -1.27 -2.49 -4.10 1.34 -2.68 -2.06 -2.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining
Localization
Cell Percentages nucleus (95%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Fyv6

Fyv6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fyv6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available