Standard name
Human Ortholog
Description Component of the BUB2-dependent spindle checkpoint pathway; interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.13 0.08 0.09 0 0 0 0 0 0
Cytoplasm 0.92 0.96 0.96 0.96 0.95 0.86 0.74 0.81 0.63 0.67 0.52 0.59 0.99 0.99 1.0 0.89 0.89 0.91 0.85 0.81 0.69 0.81 0.81 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.15 0 0.05 0 0.06 0.19 0.42 0.27 0.58 0.51 0.67 0.52 0 0 0 0 0 0 0.07 0 0.18 0.08 0.1 0.07
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.09 0.07 0 0.06 0.05 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 1 2 0 0 0 1 0 1 1 1 0 1 0 3 1 1 0 1 0 0 2 3
Bud 3 0 2 1 0 3 5 12 14 6 8 6 0 0 0 1 0 2 0 0 0 0 1 2
Bud Neck 0 0 0 0 1 0 0 1 1 1 0 0 0 0 0 0 0 0 2 0 0 0 2 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 6 4 5 5 0 4 3 1 2 1 4 1 1 3 44 21 31 0 0 0 0 0 0
Cytoplasm 181 128 162 170 224 198 238 310 141 177 114 131 111 157 163 301 232 310 179 112 132 87 194 171
Endoplasmic Reticulum 1 4 2 0 0 2 0 0 0 0 1 3 0 1 0 8 11 12 2 2 5 4 8 5
Endosome 0 0 1 1 3 1 3 3 0 0 0 2 1 0 0 5 8 10 3 1 3 0 1 1
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0
Mitochondria 29 4 9 6 13 44 134 105 130 134 145 116 0 0 0 2 9 12 14 5 34 8 23 14
Nucleus 0 1 0 1 2 0 0 1 0 1 2 1 0 0 0 3 0 0 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 1 1 5 0 1 1 2 0 0 0 5 1 1 1 0 0 0 0 1
Vac/Vac Membrane 0 0 2 5 4 7 4 5 3 3 1 5 0 0 0 26 23 25 2 8 8 1 3 2
Unique Cell Count 196 134 169 177 235 231 320 382 224 265 218 223 112 158 163 338 261 342 211 139 192 107 242 205
Labelled Cell Count 214 144 183 192 253 256 390 447 290 326 275 271 113 160 166 399 307 406 211 139 192 107 242 205


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.3 6.3 5.4 5.7 5.7 4.4 4.1 4.7 3.8 3.9 3.6 4.0 5.8 6.2 6.4 8.0 7.4 7.3 5.5 6.1 6.3
Std Deviation (1e-4) 0.5 0.9 0.9 1.9 2.0 1.6 1.5 1.8 1.1 1.0 1.2 0.8 0.9 0.9 2.0 1.2 1.4 1.3 1.4 1.5 1.0
Intensity Change (Log2) – – – 0.09 0.08 -0.28 -0.4 -0.19 -0.51 -0.47 -0.56 -0.42 0.11 0.19 0.24 0.57 0.46 0.43 0.03 0.18 0.23


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 3.9 2.5 2.8
Cytoplasm 0.1 -0.3 -3.3 -5.9 -4.5 -7.7 -7.1 -9.4 -8.4 1.6 2.1 2.6 -2.6 -2.5 -2.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 1.8 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.9 0.1 0 0 0 0 0 0 0 0 0 0 0 -0.9 -1.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 3.0 3.3 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2238 1.6758 1.8099 1.6163 1.6354 1.7494 0.344 0.7588 0.7789 0.6453 0.758 0.7821 -0.4221 0.0493 0.1443 0.0277 0.4111 0.2035
Actin 0.0105 0.0008 0.0129 0.0061 0.0089 0.0076 0.0234 0.0004 0.0059 0.0437 0.0282 0.0051 0.0173 0.0019 0.0217 0.0174 0.0133 0.0157
Bud 0.0034 0.0033 0.0022 0.0006 0.0034 0.0006 0.0048 0.0072 0.0024 0.0006 0.0007 0.0123 0.0002 0.0003 0.001 0.0009 0.0005 0.0002
Bud Neck 0.0031 0.0003 0.001 0.0008 0.0008 0.001 0.0025 0.0003 0.0022 0.0018 0.0028 0.0032 0.0018 0.0029 0.0008 0.0005 0.0003 0.005
Bud Periphery 0.0033 0.0023 0.0036 0.0008 0.0015 0.0008 0.0038 0.0038 0.0029 0.0011 0.0006 0.0107 0.0003 0.0002 0.0011 0.0012 0.0007 0.0002
Bud Site 0.0113 0.0173 0.0049 0.0021 0.0031 0.0003 0.0059 0.0048 0.0048 0.0015 0.0031 0.0023 0.0035 0.0047 0.0138 0.0008 0.001 0.0005
Cell Periphery 0.0013 0.0004 0.0005 0.0003 0.0003 0.0001 0.0007 0.0006 0.0003 0.0002 0.0002 0.0005 0.0004 0.0004 0.0004 0.0002 0.0001 0.0001
Cytoplasm 0.3991 0.5939 0.4 0.4008 0.4941 0.5174 0.3225 0.5214 0.491 0.3827 0.3758 0.5031 0.5916 0.6967 0.5998 0.7023 0.4745 0.7458
Cytoplasmic Foci 0.0383 0.0166 0.0379 0.0443 0.0385 0.0225 0.0292 0.0188 0.0251 0.0374 0.1146 0.0232 0.0509 0.0186 0.0326 0.0327 0.0343 0.0282
Eisosomes 0.0004 0.0002 0.0002 0.0002 0.0002 0.0001 0.0006 0.0002 0.0005 0.0005 0.0001 0.0001 0.0001 0.0001 0.0002 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.0056 0.0021 0.0043 0.0033 0.0029 0.0027 0.0076 0.002 0.0035 0.0022 0.0027 0.0024 0.0096 0.0024 0.0045 0.0035 0.002 0.0033
Endosome 0.0208 0.0125 0.0334 0.0537 0.0432 0.0167 0.0192 0.0146 0.0181 0.0282 0.0552 0.013 0.033 0.0109 0.0213 0.0919 0.0357 0.0298
Golgi 0.0064 0.002 0.0135 0.013 0.0173 0.0039 0.0046 0.0009 0.0018 0.005 0.0127 0.001 0.0053 0.0042 0.0081 0.0084 0.0205 0.0076
Lipid Particles 0.0081 0.0002 0.0115 0.0231 0.0096 0.0006 0.0103 0.0003 0.001 0.0115 0.0096 0.0014 0.0071 0.0007 0.0103 0.0014 0.0405 0.003
Mitochondria 0.0184 0.0019 0.0109 0.011 0.0684 0.0034 0.0059 0.0006 0.0013 0.0013 0.0019 0.0013 0.0029 0.007 0.0152 0.0258 0.1105 0.0029
None 0.4414 0.3405 0.4321 0.4079 0.2717 0.4058 0.5195 0.4152 0.4154 0.4552 0.3455 0.4057 0.2539 0.2422 0.237 0.0899 0.2308 0.1489
Nuclear Periphery 0.0048 0.0004 0.0018 0.0009 0.0074 0.0065 0.0055 0.0006 0.003 0.0014 0.0017 0.0021 0.0013 0.0005 0.0011 0.0012 0.0009 0.0009
Nucleolus 0.0012 0.0001 0.0005 0.0002 0.0014 0.0002 0.0013 0.0002 0.0012 0.0003 0.001 0.0004 0.0004 0.0002 0.0002 0.0003 0.0003 0.0001
Nucleus 0.0042 0.001 0.0022 0.0009 0.004 0.0018 0.0069 0.0023 0.0054 0.0014 0.0025 0.0035 0.0009 0.0012 0.0012 0.0015 0.0009 0.0008
Peroxisomes 0.0063 0.0003 0.0131 0.0233 0.0052 0.0015 0.014 0.0002 0.0023 0.0154 0.0096 0.0011 0.01 0.0014 0.0171 0.0008 0.0271 0.0031
Punctate Nuclear 0.0047 0.0003 0.0081 0.0012 0.014 0.0015 0.0044 0.0012 0.0076 0.0022 0.0228 0.0043 0.0035 0.0004 0.0012 0.0004 0.0024 0.0005
Vacuole 0.0059 0.0031 0.0043 0.004 0.0027 0.0034 0.0061 0.004 0.0035 0.0051 0.0073 0.0028 0.005 0.0029 0.0096 0.0154 0.0019 0.0027
Vacuole Periphery 0.0015 0.0005 0.001 0.0014 0.0016 0.0014 0.0014 0.0005 0.0007 0.0011 0.0015 0.0006 0.0009 0.0003 0.0017 0.0034 0.0015 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.8367 7.4725 7.6243 12.0159 11.5153 8.3545 10.1527 10.5176 10.1484 11.9436
Translational Efficiency 2.515 2.5504 2.3547 1.2616 1.275 1.7117 1.6879 1.3179 1.1403 1.0798

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1332 452 2331 206 2009 1947 315 1498 3341 2399 2646 1704

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 712.46 854.84 837.37 980.88 738.26 797.71 944.61 925.94 727.97 808.47 850.14 932.58
Standard Deviation 81.10 102.66 99.77 113.61 85.19 95.53 105.28 122.37 84.53 99.46 106.28 122.66
Intensity Change Log 2 — 0.262845 0.233056 0.461268 — 0.111735 0.355590 0.326790 — 0.187925 0.296712 0.394400

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000393 0.000583 0.000120 0.000940 0.000240 0.000333 0.000111 0.002317 0.000301 0.000380 0.000119 0.002151
Bud Neck 0.032514 0.018480 0.007405 0.002618 0.014398 0.025709 0.001499 0.005203 0.021621 0.024347 0.006702 0.004890
Bud Site 0.022939 0.042050 0.017446 0.029689 0.009154 0.030071 0.004586 0.036259 0.014650 0.032328 0.015915 0.035465
Cell Periphery 0.000286 0.000159 0.000115 0.000165 0.000136 0.000185 0.000164 0.000083 0.000196 0.000180 0.000120 0.000093
Cytoplasm 0.351934* 0.366610* 0.633568* 0.398322* 0.480275* 0.384831* 0.558404* 0.671047* 0.429108* 0.381398* 0.624620* 0.638077*
Cytoplasmic Foci 0.385661* 0.366063* 0.060166 0.120824 0.307294* 0.252107* 0.107719 0.058112 0.338538* 0.273578* 0.065827 0.065693
Eisosomes 0.000509 0.000141 0.000040 0.000066 0.000172 0.000082 0.000086 0.000029 0.000306 0.000093 0.000045 0.000033
Endoplasmic Reticulum 0.002741 0.002777 0.000902 0.001645 0.002175 0.001402 0.001202 0.000434 0.002400 0.001661 0.000937 0.000580
Endosome 0.046746 0.059316 0.006932 0.019813 0.027404 0.061976 0.013473 0.009948 0.035116 0.061475 0.007711 0.011140
Golgi 0.029184 0.013416 0.000765 0.000635 0.011203 0.010845 0.000145 0.005457 0.018372 0.011329 0.000691 0.004874
Lipid Particles 0.012414 0.004200 0.001587 0.002469 0.008709 0.004697 0.002898 0.001064 0.010186 0.004603 0.001743 0.001234
Mitochondria 0.024790 0.003334 0.000924 0.001733 0.004434 0.011153 0.000108 0.004579 0.012549 0.009680 0.000827 0.004235
Mitotic Spindle 0.001732 0.001586 0.008252 0.018723 0.001832 0.010435 0.001361 0.026132 0.001792 0.008768 0.007432 0.025236
None 0.000842 0.002504 0.002029 0.000913 0.001135 0.002466 0.001262 0.001842 0.001018 0.002473 0.001938 0.001730
Nuclear Periphery 0.000148 0.000098 0.000422 0.000402 0.000224 0.000205 0.000545 0.000355 0.000194 0.000185 0.000436 0.000361
Nuclear Periphery Foci 0.000220 0.000602 0.000636 0.008730 0.000493 0.000234 0.003277 0.001042 0.000384 0.000303 0.000951 0.001971
Nucleolus 0.000352 0.000396 0.000852 0.000168 0.000574 0.000983 0.000367 0.000237 0.000485 0.000873 0.000795 0.000229
Nucleus 0.017446 0.012046 0.090369 0.025279 0.038252 0.021805 0.107409 0.028149 0.029957 0.019966 0.092398 0.027802
Peroxisomes 0.008153 0.010939 0.001591 0.004420 0.004094 0.006067 0.000421 0.005671 0.005712 0.006985 0.001452 0.005520
Vacuole 0.053291 0.089081 0.165107 0.362000* 0.084394 0.165482 0.194694 0.139697 0.071994 0.151088 0.168629 0.166572
Vacuole Periphery 0.007705 0.005619 0.000771 0.000445 0.003408 0.008932 0.000270 0.002342 0.005122 0.008307 0.000711 0.002113

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.49 6.61 -2.45 -0.93 -4.42 -0.90 2.85 -1.78 -1.58 -1.99 -0.91 6.23 -1.78 -1.59 -2.15
Bud Neck 5.36 11.87 14.41 9.38 6.32 -7.35 16.58 11.42 15.26 -4.80 -1.81 13.86 16.97 16.94 3.47
Bud Site -5.10 3.45 0.73 4.72 -1.41 -10.75 3.42 -6.29 2.49 -7.55 -9.92 -0.04 -3.98 3.81 -3.48
Cell Periphery 5.83 9.24 7.12 1.40 -1.27 -0.67 -1.93 10.03 1.69 7.66 0.27 6.65 14.55 1.86 3.55
Cytoplasm -1.11 -31.14 0.13 0.82 14.65 11.21 -3.55 -12.46 -21.61 -4.08 6.62 -26.48 -16.27 -20.29 4.86
Cytoplasmic Foci 1.70 53.42 28.81 20.36 -3.77 8.48 27.61 48.30 37.84 7.22 11.51 66.42 63.90 43.37 2.00
Eisosomes 5.21 6.79 6.43 5.52 -5.40 11.81 9.42 20.22 16.16 10.15 7.52 9.32 9.71 15.86 4.58
Endoplasmic Reticulum -0.01 4.99 2.63 0.82 -3.26 2.21 2.92 6.92 3.80 5.49 1.92 6.60 8.53 3.24 3.20
Endosome -2.68 17.48 9.06 9.13 -2.30 -14.57 8.22 15.98 26.26 4.70 -12.12 22.56 21.27 28.16 0.46
Golgi 8.18 18.45 18.86 10.73 1.04 0.41 17.17 9.90 9.67 -3.81 7.69 23.06 17.79 11.86 -2.74
Lipid Particles 7.27 12.45 10.76 2.19 -3.24 5.90 8.46 12.15 10.18 4.37 9.65 16.66 16.93 10.28 2.08
Mitochondria 9.37 10.88 10.61 2.68 0.08 -6.39 8.23 2.51 7.57 -2.52 2.43 12.02 9.13 7.59 -1.58
Mitotic Spindle 0.28 -4.41 -2.86 -2.90 -1.99 -5.09 0.35 -8.00 -4.10 -7.59 -5.08 -4.53 -8.54 -5.15 -5.62
None -0.75 -2.08 -0.41 0.65 1.33 -1.82 0.01 -3.14 0.79 -2.64 -2.00 -1.91 -3.37 0.94 -0.03
Nuclear Periphery 1.59 -6.68 -4.71 -5.11 -2.59 0.31 -5.89 -5.04 -6.36 0.45 0.17 -6.17 -7.18 -7.87 -2.46
Nuclear Periphery Foci -4.62 -3.40 -4.79 -4.59 -4.57 1.37 -6.07 -4.37 -9.79 4.29 0.64 -3.69 -7.03 -7.78 -4.91
Nucleolus -0.72 -2.20 2.10 2.97 2.95 -2.00 2.80 2.13 3.07 -0.37 -2.37 -1.42 1.91 3.19 2.22
Nucleus 3.41 -24.23 -3.92 -5.39 14.84 10.67 -9.25 -1.99 -10.67 8.60 8.65 -21.96 -6.25 -12.06 16.29
Peroxisomes -2.31 11.22 4.36 5.27 -1.22 -3.33 9.36 0.96 3.09 -3.51 -2.43 10.79 3.20 4.56 -2.40
Vacuole -6.36 -26.01 -19.93 -17.55 -13.32 -16.49 -11.49 -21.31 -8.40 -0.41 -19.60 -25.39 -28.10 -14.34 -9.65
Vacuole Periphery 2.06 11.78 12.47 6.22 3.21 -10.99 13.50 5.46 13.72 -2.24 -6.55 15.62 9.87 14.44 -1.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the BUB2-dependent spindle checkpoint pathway; interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
Localization
Cell Percentages cytoplasm (84%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ibd2

Ibd2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ibd2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available