Standard name
Human Ortholog
Description Basic leucine zipper transcription factor of the ATF/CREB family; forms a complex with Tup1p and Cyc8p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.1 0.12 0.06 0.1 0.07 0 0.05 0 0 0.1 0.14 0.26 0.1 0.11 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.17 0 0 0.08 0 0.19 0.15 0.19 0.46 0.31 0.56 0.41 0 0 0 0.08 0 0.05 0 0 0 0 0 0
Nucleus 0.88 0.92 0.92 0.78 0.83 0.77 0.79 0.76 0.68 0.73 0.69 0.73 0.91 0.84 0.7 0.81 0.76 0.81 0.68 0.74 0.7 0.73 0.65 0.64
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.15 0.11 0.13 0.11 0 0 0 0 0.05 0 0.14 0.13 0.09 0.08 0.13 0.14
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.05 0 0.06 0.06 0.05 0 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0.06 0 0.1 0.09 0.09 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0
Bud 1 0 0 0 0 1 1 2 0 2 0 3 0 0 0 1 0 0 0 4 2 2 1 0
Bud Neck 1 0 1 1 0 1 1 3 1 4 1 1 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 0 0 5 3 1 6 4 9 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 4 7 14 18 11 21 14 3 9 5 6 12 28 32 35 31 21 0 3 1 3 2 1
Endoplasmic Reticulum 1 1 0 1 0 1 2 1 0 1 0 0 0 0 0 8 11 8 0 0 0 0 1 0
Endosome 1 5 1 5 1 1 2 3 0 2 0 1 0 2 0 6 12 10 2 6 7 0 1 2
Golgi 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 0 0 0 1
Mitochondria 26 5 3 11 4 36 33 38 38 52 91 83 0 0 1 28 12 15 3 2 2 0 2 4
Nucleus 136 268 169 110 125 148 170 154 56 121 112 148 111 167 88 288 222 254 116 250 150 82 93 114
Nuclear Periphery 0 0 0 3 1 1 3 3 0 1 2 0 0 0 0 6 7 0 0 0 0 0 0 0
Nucleolus 6 11 2 5 1 8 8 7 12 19 21 22 0 3 1 11 16 10 24 45 19 9 18 25
Peroxisomes 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 7 8 11 8 8 5 16 11 0 2 3 7 4 5 1 7 8 10 7 8 6 3 6 7
Vac/Vac Membrane 2 7 6 3 1 9 1 1 3 1 0 1 1 0 4 17 13 18 10 12 20 10 12 14
Unique Cell Count 155 291 184 141 150 191 214 203 82 166 163 202 122 199 125 357 292 315 172 340 215 114 143 178
Labelled Cell Count 184 311 200 163 159 222 264 240 114 220 239 281 129 205 128 408 333 348 172 340 215 114 143 178


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 5.7 6.1 6.1 6.5 5.1 5.1 5.3 4.3 4.9 4.3 4.2 6.2 6.2 6.3 7.3 8.1 7.3 5.2 6.0 6.1
Std Deviation (1e-4) 0.9 1.0 1.2 1.9 2.1 1.3 1.5 1.4 1.1 1.7 1.3 0.9 1.0 1.2 1.7 1.7 2.1 1.9 0.7 1.4 1.4
Intensity Change (Log2) – – – -0.0 0.1 -0.24 -0.25 -0.19 -0.49 -0.31 -0.48 -0.53 0.03 0.04 0.06 0.27 0.42 0.27 -0.22 -0.03 0.02

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.2 2.8 0.9 2.3 1.3 0 0.7 -0.4 -0.5 2.1 3.5 5.7 2.5 2.7 1.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 2.3 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.7 0 5.5 4.8 5.5 0 7.6 0 0 0 0 0 2.9 1.5 1.8
Nucleus -3.5 -2.4 -3.8 -3.5 -4.2 -4.9 -4.7 -5.5 -4.8 -0.3 -2.4 -4.9 -3.4 -4.4 -3.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 4.1 0 0 0 0 0 0 2.4 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole -0.1 -0.3 -1.6 0.6 -0.2 0 -2.4 0 0 -1.1 -1.7 0 -2.5 -1.8 -1.5
Vacuole 0 0 0.7 0 0 0 0 0 0 0 0 0 0.8 0.6 1.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.7603 0.8488 0.7653 0.3123 0.2613 0.5126 1.0215 0.8342 0.8991 1.1479 1.0464 0.672 1.833 1.1378 0.8389 1.8038 1.2887 1.2143
Actin 0.0048 0.0001 0.0075 0.0026 0.0058 0.0014 0.0143 0.0008 0.0011 0.003 0.0178 0.0001 0.0347 0 0.015 0.0663 0.0122 0.0059
Bud 0.0005 0.0011 0.0003 0.0002 0.0014 0.0002 0.0003 0.0001 0.0002 0.0003 0.0026 0.0001 0.0009 0 0.0001 0.0006 0.002 0.0001
Bud Neck 0.0034 0.0005 0.0007 0.0002 0.0012 0.002 0.0023 0.0001 0.0003 0.0017 0.001 0.0009 0.0045 0.0001 0.0005 0.0011 0.0047 0.0012
Bud Periphery 0.0017 0.0002 0.0004 0.0004 0.0045 0.0002 0.0005 0.0002 0.0005 0.0004 0.0055 0.0002 0.0023 0 0.0002 0.0011 0.006 0.0002
Bud Site 0.0028 0.0011 0.0015 0.0006 0.0035 0.0003 0.0058 0.0003 0.0016 0.0016 0.0067 0.0001 0.0119 0.0001 0.0004 0.0021 0.0042 0.0001
Cell Periphery 0.0003 0 0.0002 0 0.0013 0.0001 0.0002 0 0.0001 0.0001 0.0002 0.0001 0.0006 0 0 0.0002 0.0015 0
Cytoplasm 0.0074 0.0009 0.0028 0.0017 0.0013 0.0023 0.0013 0.0004 0.0014 0.0079 0.0008 0.0003 0.0047 0.0004 0.0002 0.0004 0.0089 0.0025
Cytoplasmic Foci 0.0279 0.0001 0.0142 0.0073 0.0122 0.0059 0.0161 0.0003 0.0015 0.0154 0.0063 0.0001 0.0087 0 0.0092 0.0016 0.0134 0.0005
Eisosomes 0 0 0.0001 0 0.0001 0 0.0001 0 0 0.0001 0.0002 0 0.0004 0 0 0.0006 0.0002 0
Endoplasmic Reticulum 0.002 0 0.0034 0.0002 0.0007 0.0004 0.0026 0.0001 0.0011 0.0036 0.0013 0.0001 0.0049 0 0.0001 0.0007 0.0046 0.0038
Endosome 0.0303 0 0.01 0.0092 0.0797 0.0119 0.0168 0.001 0.0037 0.0271 0.0574 0.0003 0.0119 0 0.0017 0.0056 0.0339 0.0067
Golgi 0.0099 0 0.0064 0.0142 0.0178 0.0042 0.0066 0.0006 0.0009 0.0038 0.0373 0 0.0037 0 0.0023 0.0086 0.0192 0.0011
Lipid Particles 0.0354 0 0.0048 0.0035 0.0504 0.0115 0.0168 0.0007 0.0093 0.0199 0.0091 0 0.0036 0 0.0081 0.0059 0.0488 0.0016
Mitochondria 0.005 0.0001 0.0173 0.027 0.0257 0.0046 0.0038 0.0081 0.0032 0.0022 0.0167 0.0003 0.0061 0.0002 0.0045 0.0772 0.0526 0.0011
None 0.0013 0.0002 0.0027 0.0027 0.0005 0.0013 0.0018 0.0008 0.0005 0.0495 0.0008 0.0002 0.004 0.0011 0.0003 0.0005 0.0167 0.0015
Nuclear Periphery 0.0066 0.006 0.0066 0.0094 0.0065 0.0036 0.0107 0.0042 0.0071 0.0457 0.0047 0.0026 0.0222 0.001 0.001 0.003 0.0241 0.0203
Nucleolus 0.0404 0.0327 0.0257 0.0213 0.0816 0.09 0.0199 0.0232 0.0139 0.0188 0.027 0.0496 0.0397 0.038 0.0198 0.0192 0.07 0.0738
Nucleus 0.7806 0.9513 0.8625 0.8866 0.5978 0.8319 0.8427 0.9503 0.9481 0.738 0.7863 0.9243 0.808 0.9493 0.9237 0.7915 0.6107 0.8603
Peroxisomes 0.0192 0 0.0074 0.009 0.0067 0.0014 0.0221 0.0011 0.0023 0.0066 0.005 0 0.0027 0 0.0058 0.0022 0.0211 0.0002
Punctate Nuclear 0.0119 0.0056 0.0207 0.0025 0.0521 0.0252 0.0126 0.0074 0.0017 0.0491 0.0059 0.0197 0.0209 0.0095 0.0069 0.0097 0.0141 0.0179
Vacuole 0.0064 0.0001 0.0032 0.0006 0.0368 0.0009 0.0015 0.0002 0.001 0.0034 0.0038 0.0009 0.0019 0.0001 0.0002 0.0008 0.0202 0.0004
Vacuole Periphery 0.0021 0.0001 0.0015 0.0006 0.0123 0.0006 0.0012 0.0002 0.0005 0.0017 0.0036 0.0003 0.0016 0 0.0001 0.0011 0.0107 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.3116 12.6849 10.5423 17.5672 14.7182 16.4511 14.8778 17.8323 15.1825 19.1619
Translational Efficiency 1.4884 1.4191 1.3711 0.9113 1.2324 1.6429 0.9763 0.9969 1.1647 1.1419

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
76 1266 308 1753 867 1971 1186 66 943 3237 1494 1819

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 593.29 705.70 959.61 936.94 754.86 735.10 928.30 942.41 741.84 723.60 934.75 937.14
Standard Deviation 70.70 110.96 137.29 129.73 83.04 106.91 124.55 163.46 93.15 109.45 127.91 131.11
Intensity Change Log 2 — 0.250318 0.693711 0.659219 — -0.038269 0.298382 0.320146 — 0.095889 0.485809 0.479253

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000072 0.001013 0.002102 0.001285 0.000340 0.000343 0.000991 0.001243 0.000319 0.000605 0.001220 0.001283
Bud Neck 0.000963 0.009319 0.015698 0.024571 0.002654 0.011830 0.014679 0.005455 0.002517 0.010848 0.014889 0.023878
Bud Site 0.000185 0.001957 0.002591 0.008963 0.000706 0.001488 0.001899 0.001989 0.000664 0.001672 0.002042 0.008710
Cell Periphery 0.000172 0.000143 0.000109 0.000494 0.000054 0.000072 0.000101 0.000114 0.000064 0.000100 0.000103 0.000480
Cytoplasm 0.099777 0.025429 0.002428 0.021217 0.012132 0.014831 0.006866 0.037290 0.019196 0.018976 0.005951 0.021800
Cytoplasmic Foci 0.023405 0.004245 0.000090 0.001239 0.004230 0.002196 0.000153 0.000061 0.005775 0.002997 0.000140 0.001196
Eisosomes 0.000064 0.000040 0.000053 0.000033 0.000035 0.000024 0.000034 0.000040 0.000037 0.000030 0.000037 0.000033
Endoplasmic Reticulum 0.000590 0.003955 0.008891 0.005410 0.002223 0.002520 0.005586 0.005921 0.002091 0.003081 0.006267 0.005429
Endosome 0.000707 0.001522 0.000394 0.002150 0.000898 0.001152 0.000480 0.000301 0.000882 0.001297 0.000462 0.002083
Golgi 0.000227 0.001044 0.000194 0.001051 0.000544 0.000673 0.000140 0.000149 0.000518 0.000818 0.000151 0.001018
Lipid Particles 0.005336 0.002121 0.000322 0.000237 0.001530 0.001125 0.000218 0.000233 0.001837 0.001514 0.000240 0.000237
Mitochondria 0.002365 0.004308 0.001803 0.003444 0.001717 0.005839 0.001495 0.000969 0.001769 0.005240 0.001559 0.003354
Mitotic Spindle 0.000087 0.009054 0.002536 0.029371 0.002525 0.012659 0.002779 0.004630 0.002329 0.011249 0.002729 0.028474
None 0.058796 0.021305 0.003823 0.011904 0.007264 0.007376 0.005300 0.018499 0.011417 0.012824 0.004995 0.012144
Nuclear Periphery 0.001708 0.001304 0.000564 0.002022 0.000912 0.003045 0.000786 0.000657 0.000976 0.002364 0.000740 0.001973
Nuclear Periphery Foci 0.001037 0.002518 0.000394 0.000595 0.001186 0.000979 0.000450 0.000372 0.001174 0.001581 0.000438 0.000587
Nucleolus 0.064526 0.067262 0.025850 0.012240 0.047134 0.058331 0.018028 0.019430 0.048536 0.061824 0.019640 0.012501
Nucleus 0.736824 0.839713 0.927555 0.868432 0.912181 0.872019 0.936945 0.899548 0.898048 0.859384 0.935009 0.869561
Peroxisomes 0.001775 0.001528 0.000715 0.000234 0.000823 0.000830 0.000290 0.000411 0.000900 0.001103 0.000378 0.000241
Vacuole 0.001224 0.001442 0.003630 0.004604 0.000708 0.001869 0.002555 0.002525 0.000750 0.001702 0.002777 0.004528
Vacuole Periphery 0.000159 0.000778 0.000258 0.000504 0.000205 0.000800 0.000226 0.000160 0.000201 0.000792 0.000233 0.000491

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.93 -14.91 -15.77 -3.01 5.83 -0.07 -13.80 -5.85 -5.86 -3.60 -5.01 -17.72 -12.71 -9.51 0.68
Bud Neck -12.29 -12.93 -24.68 -15.41 -6.15 -12.53 -17.94 -5.19 -2.04 0.63 -15.41 -21.05 -23.53 -15.89 -8.49
Bud Site -9.12 -10.75 -8.81 -5.92 -3.65 -2.41 -5.85 -4.86 -4.29 -3.54 -3.91 -7.49 -8.07 -6.80 -5.42
Cell Periphery 0.88 1.63 -0.69 -1.11 -1.44 -1.00 -3.78 -4.71 -4.21 -3.24 -3.07 -3.48 -2.15 -1.74 -1.72
Cytoplasm 3.44 4.59 3.91 3.79 -10.30 -1.10 3.60 -1.25 -1.05 -1.89 0.11 5.72 1.13 1.70 -8.43
Cytoplasmic Foci 2.89 3.38 3.33 4.40 -1.63 1.94 4.30 4.23 5.07 -1.27 2.74 5.38 4.99 5.59 -1.63
Eisosomes 2.41 0.62 2.48 0.17 4.78 4.89 -1.55 -3.89 -5.05 -3.55 3.41 -2.13 -0.79 -5.71 1.71
Endoplasmic Reticulum -11.46 -11.47 -23.45 -8.08 3.33 -0.78 -14.02 -5.39 -5.28 -2.49 -3.90 -16.42 -16.02 -14.33 0.76
Endosome -1.33 0.82 -0.80 0.61 -1.78 -0.41 1.27 0.09 0.68 -2.13 -0.84 1.30 -0.51 0.27 -2.06
Golgi -2.25 0.17 -1.04 1.47 -1.16 -0.36 1.67 0.71 1.43 -3.57 -1.03 1.62 0.20 1.34 -1.56
Lipid Particles 3.29 4.92 5.02 2.96 1.66 1.65 5.90 4.00 1.94 -2.29 1.79 7.14 7.04 4.32 -0.56
Mitochondria -2.10 0.95 -1.81 1.02 -6.58 -4.55 -0.23 -0.68 4.79 -0.97 -4.90 -0.21 -3.55 2.95 -9.24
Mitotic Spindle -6.04 -2.44 -11.46 -6.73 -8.66 -4.81 -1.86 -2.54 -2.02 -2.38 -5.59 -2.00 -10.12 -6.99 -9.28
None 3.10 4.66 4.18 7.48 -7.29 0.03 3.78 -1.10 -1.11 -1.70 -0.75 5.87 2.20 4.39 -6.49
Nuclear Periphery 0.45 0.88 -1.58 -8.11 -10.01 -3.85 -1.44 -2.32 0.62 -1.98 -3.80 -0.75 -8.88 -2.68 -10.14
Nuclear Periphery Foci -2.87 1.64 1.20 4.46 -0.99 1.97 3.40 2.13 0.59 -0.82 -0.61 3.66 3.05 4.28 -0.87
Nucleolus 0.14 2.92 4.37 16.09 3.72 -2.11 9.46 7.01 9.46 0.69 -2.83 9.30 11.59 21.86 3.59
Nucleus -3.50 -5.94 -4.24 -2.78 6.57 5.19 -3.16 3.03 1.80 3.73 5.25 -4.77 4.83 0.06 12.06
Peroxisomes 0.98 1.80 2.38 7.03 7.32 -0.31 5.24 1.38 1.45 -2.71 -0.89 4.81 5.94 7.63 4.72
Vacuole -0.15 -3.63 -6.40 -8.81 -0.97 -3.14 -5.39 -2.99 -2.84 -2.42 -3.18 -6.73 -10.26 -9.02 -3.79
Vacuole Periphery -2.31 -3.85 -3.07 1.68 -0.28 -3.32 0.12 -1.29 2.82 -1.68 -3.78 -0.33 -1.80 3.09 -1.94
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Basic leucine zipper transcription factor of the ATF/CREB family; forms a complex with Tup1p and Cyc8p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Sko1

Sko1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sko1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available