Standard name
Human Ortholog
Description Cell cycle-regulated gene of unknown function; promoter bound by Fkh2p; null mutant is sensitive to expression of the top1-T722A allele; TDA7 has a paralog, YDL211C, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.29 0.48 0.53 0.81 0.56 0.76 0.81 0.91 0.86 0.86 0.91 0.92 0.83 0.97 0.98 0.23 0.28 0.28 0 0 0 0 0.1 0.08
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.18 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.12 0.05 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0.28 0.19 0.28 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.63 0.63 0.6 0.32 0.56 0.35 0.31 0.15 0.18 0.25 0.05 0.11 0.2 0 0 0.73 0.65 0.57 0.88 0.86 0.89 0.85 0.8 0.84
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 0 0 1 0 1 1 0 2 0 3 1 0 0 1 0 0 0 1 4 1 3 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 62 139 62 148 115 172 270 262 211 263 211 258 142 203 246 34 52 47 4 12 4 5 21 20
Endoplasmic Reticulum 0 5 0 0 1 1 2 0 0 1 0 4 1 1 0 8 9 6 1 0 0 0 1 0
Endosome 2 7 2 2 4 0 1 1 0 3 1 0 1 0 1 7 5 7 5 8 2 2 2 2
Golgi 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 3 1 0 0 0 1
Mitochondria 38 6 0 0 0 5 2 3 5 8 18 6 0 0 0 4 3 6 4 7 3 2 7 4
Nucleus 25 15 2 1 12 7 10 6 9 2 6 4 1 1 0 42 35 47 2 2 0 1 2 1
Nuclear Periphery 2 1 0 0 0 0 1 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 1 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 2 1
Vac/Vac Membrane 135 182 70 58 116 79 105 42 44 75 11 31 35 8 7 108 122 95 210 281 119 115 181 209
Unique Cell Count 215 289 117 182 207 225 334 287 244 306 232 279 171 209 251 148 189 167 240 326 134 135 228 251
Labelled Cell Count 264 357 138 210 248 265 392 315 272 354 252 305 180 215 255 203 229 208 240 326 134 135 228 251


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.7 5.3 6.2 6.3 6.9 5.7 5.7 6.1 5.1 5.2 4.7 4.9 5.8 5.7 5.3 7.7 8.2 7.7 6.1 6.0 6.0
Std Deviation (1e-4) 0.8 1.0 2.0 2.1 1.9 1.3 1.5 1.3 1.5 1.4 1.2 0.9 1.0 1.3 1.3 1.9 2.0 1.7 1.5 1.5 1.2
Intensity Change (Log2) – – – 0.01 0.15 -0.14 -0.13 -0.03 -0.28 -0.26 -0.4 -0.34 -0.11 -0.13 -0.23 0.31 0.39 0.31 -0.03 -0.05 -0.06

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 5.2 0.4 4.4 5.9 8.8 6.9 7.2 8.1 9.1 5.5 9.8 10.9 -5.0 -4.5 -4.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 1.7 0 0 0 0 0 0 0 0 0 0 5.8 4.4 5.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.8 -0.7 -4.4 -5.4 -9.2 -8.0 -6.8 -11.5 -10.1 -6.8 -11.4 -12.5 2.3 0.8 -0.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5416 -0.0056 -0.1087 0.0753 0.2695 0.1195 -0.2502 0.5802 0.3768 0.2468 0.8886 0.6881 0.2687 0.3001 0.0538 0.4936 0.3047 0.1566
Actin 0.0285 0.0005 0.0267 0.0298 0.0122 0.0004 0.0179 0.005 0.0108 0.0338 0.0587 0.0059 0.0413 0.0002 0.0085 0.0016 0.0193 0.0006
Bud 0.0007 0.0006 0.0042 0.0008 0.0013 0.0004 0.0005 0.0021 0.0009 0.002 0.0061 0.0013 0.0017 0.0133 0.0056 0.0012 0.0038 0.0009
Bud Neck 0.0107 0.0008 0.0017 0.0008 0.0252 0.0089 0.0008 0.0062 0.0015 0.0014 0.0168 0.0032 0.003 0.0052 0.0024 0.0037 0.0049 0.0032
Bud Periphery 0.0008 0.0006 0.0018 0.0011 0.0015 0.0009 0.0011 0.004 0.0033 0.0034 0.0126 0.0039 0.003 0.0057 0.0049 0.0047 0.0053 0.0018
Bud Site 0.0174 0.0041 0.0068 0.0015 0.0214 0.0005 0.0016 0.0098 0.0032 0.0044 0.0185 0.0018 0.005 0.0217 0.0135 0.0027 0.0033 0.0026
Cell Periphery 0.0009 0.0005 0.0007 0.0002 0.0008 0.0005 0.0015 0.0019 0.0015 0.0007 0.0022 0.0017 0.0009 0.0012 0.0007 0.0009 0.0004 0.0006
Cytoplasm 0.1067 0.2151 0.1463 0.1241 0.0673 0.2131 0.0996 0.1718 0.0973 0.0235 0.0733 0.1077 0.0875 0.2057 0.1396 0.0413 0.0324 0.1357
Cytoplasmic Foci 0.0668 0.0656 0.0681 0.0417 0.0581 0.0648 0.0477 0.0454 0.0455 0.0334 0.0579 0.0301 0.0801 0.0526 0.049 0.0288 0.0869 0.0439
Eisosomes 0.0002 0.0001 0.0003 0.0003 0.0002 0 0.0005 0.0002 0.0003 0.0003 0.0002 0.0001 0.0006 0 0.0002 0.0001 0.0002 0
Endoplasmic Reticulum 0.008 0.0059 0.0076 0.0018 0.0027 0.0045 0.0096 0.0065 0.0047 0.0027 0.0041 0.0065 0.0094 0.0039 0.0046 0.007 0.0034 0.0036
Endosome 0.2536 0.1973 0.2664 0.3128 0.3289 0.2267 0.1981 0.157 0.2315 0.2468 0.1866 0.1891 0.2782 0.1748 0.2176 0.2558 0.3137 0.2359
Golgi 0.0138 0.003 0.0086 0.0408 0.0401 0.0103 0.0069 0.0064 0.0056 0.0159 0.0315 0.005 0.0136 0.0019 0.0033 0.0066 0.0084 0.0025
Lipid Particles 0.0335 0.008 0.0121 0.0073 0.0357 0.0083 0.0233 0.0085 0.012 0.0115 0.006 0.0088 0.0272 0.0032 0.0066 0.0279 0.0126 0.0063
Mitochondria 0.0118 0.0033 0.024 0.104 0.0404 0.0345 0.0051 0.0062 0.0341 0.0361 0.0319 0.0219 0.0059 0.0051 0.0105 0.0078 0.0066 0.0061
None 0.2147 0.2417 0.1475 0.1004 0.0081 0.1103 0.2382 0.1938 0.1695 0.1044 0.1104 0.0881 0.0755 0.1313 0.1657 0.004 0.0346 0.073
Nuclear Periphery 0.0105 0.0051 0.0116 0.0017 0.0051 0.0042 0.0105 0.0048 0.0041 0.0053 0.0055 0.0064 0.0109 0.0041 0.0063 0.0151 0.0064 0.0052
Nucleolus 0.003 0.0018 0.0028 0.0009 0.0058 0.0028 0.0063 0.004 0.0035 0.0038 0.002 0.0029 0.0025 0.0036 0.0034 0.0022 0.003 0.0035
Nucleus 0.007 0.007 0.0078 0.0034 0.0079 0.0121 0.0067 0.0138 0.0064 0.0053 0.0057 0.0109 0.0082 0.0124 0.0096 0.0105 0.0044 0.0085
Peroxisomes 0.0065 0.0025 0.0088 0.0038 0.0084 0.0011 0.0078 0.0014 0.0018 0.0037 0.015 0.0011 0.0121 0.0017 0.0093 0.0073 0.0152 0.0013
Punctate Nuclear 0.0075 0.0018 0.0028 0.0006 0.012 0.0037 0.006 0.0018 0.002 0.0017 0.0034 0.0018 0.0134 0.0023 0.0055 0.0011 0.0085 0.007
Vacuole 0.1804 0.2163 0.2183 0.2048 0.2778 0.2689 0.2822 0.3357 0.3264 0.4043 0.3194 0.4635 0.2938 0.3211 0.3 0.5162 0.3832 0.4137
Vacuole Periphery 0.017 0.0185 0.0251 0.0173 0.0391 0.0232 0.0279 0.0139 0.0341 0.0555 0.0322 0.0384 0.0263 0.0288 0.0332 0.0537 0.0435 0.044

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.9705 17.0332 7.6602 11.8013 14.9724 8.0791 18.0051 15.6746 11.2158 19.0016
Translational Efficiency 0.7241 0.6318 1.0277 0.2872 0.4631 0.9903 0.5413 0.5635 0.615 0.5633

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1836 1618 1016 1514 303 1547 1177 51 2139 3165 2193 1565

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 603.68 773.96 918.97 951.19 746.98 737.64 884.17 999.03 623.98 756.21 900.29 952.75
Standard Deviation 65.81 102.72 94.77 126.36 75.74 91.96 106.32 145.20 83.83 99.28 102.61 127.30
Intensity Change Log 2 — 0.358475 0.606234 0.655950 — -0.018153 0.243254 0.419458 — 0.162412 0.416847 0.529972

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000219 0.000056 0.000286 0.008722 0.000069 0.000207 0.000153 0.005778 0.000198 0.000130 0.000215 0.008626
Bud Neck 0.043461 0.011879 0.004942 0.018071 0.018035 0.020244 0.006097 0.022273 0.039859 0.015968 0.005562 0.018208
Bud Site 0.016282 0.008030 0.015632 0.063648 0.005784 0.019258 0.009246 0.046454 0.014795 0.013518 0.012205 0.063088
Cell Periphery 0.000374 0.000071 0.000169 0.001488 0.000161 0.000126 0.000169 0.002667 0.000344 0.000098 0.000169 0.001526
Cytoplasm 0.365678 0.161024 0.362136 0.178403 0.191457 0.117339 0.420019 0.122259 0.340999 0.139672 0.393202 0.176573
Cytoplasmic Foci 0.148535 0.057548 0.019407 0.042680 0.111396 0.072266 0.028921 0.075196 0.143274 0.064742 0.024513 0.043740
Eisosomes 0.000485 0.000027 0.000049 0.000535 0.000109 0.000052 0.000057 0.000196 0.000432 0.000039 0.000054 0.000524
Endoplasmic Reticulum 0.002870 0.001364 0.005399 0.005000 0.000675 0.003182 0.002066 0.005365 0.002559 0.002253 0.003610 0.005012
Endosome 0.059504 0.068035 0.004643 0.055716 0.082908 0.092774 0.010420 0.078260 0.062819 0.080127 0.007743 0.056451
Golgi 0.003644 0.001368 0.000086 0.003937 0.001015 0.007110 0.000199 0.000644 0.003272 0.004175 0.000147 0.003830
Lipid Particles 0.009281 0.002496 0.002229 0.002138 0.005420 0.004855 0.002173 0.004640 0.008734 0.003649 0.002199 0.002220
Mitochondria 0.003914 0.002401 0.000494 0.002346 0.000587 0.009978 0.000656 0.000130 0.003442 0.006104 0.000581 0.002273
Mitotic Spindle 0.000093 0.001428 0.004204 0.008590 0.000047 0.008580 0.005082 0.001838 0.000087 0.004924 0.004675 0.008370
None 0.001318 0.001367 0.002483 0.000108 0.000697 0.001269 0.004634 0.000076 0.001230 0.001319 0.003638 0.000107
Nuclear Periphery 0.000277 0.000600 0.003424 0.000459 0.000304 0.000378 0.001689 0.000399 0.000281 0.000492 0.002493 0.000458
Nuclear Periphery Foci 0.000173 0.000273 0.003043 0.001644 0.000288 0.000178 0.001511 0.003788 0.000189 0.000226 0.002221 0.001714
Nucleolus 0.000607 0.001177 0.000525 0.000545 0.000760 0.001136 0.001152 0.000621 0.000629 0.001157 0.000862 0.000548
Nucleus 0.039930 0.026734 0.450780 0.016868 0.036860 0.020536 0.274213 0.012966 0.039495 0.023704 0.356015 0.016741
Peroxisomes 0.003167 0.002511 0.000291 0.002762 0.002249 0.004640 0.000536 0.010674 0.003037 0.003552 0.000422 0.003020
Vacuole 0.294265 0.638166 0.119509 0.575987 0.538117 0.595172 0.228854 0.601172 0.328808 0.617151 0.178196 0.576808
Vacuole Periphery 0.005922 0.013445 0.000268 0.010354 0.003061 0.020722 0.002152 0.004604 0.005517 0.017002 0.001279 0.010167

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 5.75 -4.43 -5.79 -5.92 -5.66 -2.42 -3.08 -1.26 -1.23 -1.24 1.96 -2.64 -5.91 -5.96 -5.85
Bud Neck 16.35 19.28 12.45 -4.34 -8.26 -0.89 4.78 -0.53 -0.21 -2.21 13.76 20.62 11.58 -1.48 -9.69
Bud Site 6.82 1.73 -11.02 -13.54 -10.65 -6.59 -0.86 -3.07 -2.03 -2.95 0.99 3.41 -11.69 -12.06 -12.77
Cell Periphery 11.12 6.18 -2.35 -3.17 -2.88 1.36 0.87 -1.40 -1.42 -1.41 10.42 7.45 -2.57 -3.25 -3.09
Cytoplasm 24.91 6.35 20.18 -3.96 11.33 5.91 -13.07 1.44 -0.94 7.45 30.34 -0.60 18.21 -7.72 18.53
Cytoplasmic Foci 20.21 34.56 26.67 5.89 -10.99 4.87 11.30 2.09 0.01 -2.70 20.22 35.53 26.95 8.96 -9.75
Eisosomes 5.41 4.97 0.17 -2.29 -2.09 4.32 3.94 -1.34 -2.50 -2.37 5.39 5.10 -0.05 -2.25 -2.13
Endoplasmic Reticulum 4.51 -10.38 -2.91 -6.55 5.32 -5.58 -12.32 -2.87 -1.20 -1.47 0.89 -7.50 -3.70 -4.50 0.96
Endosome -2.42 27.88 4.24 5.91 -17.80 -1.47 11.59 0.93 1.68 -3.99 -6.13 28.72 5.16 10.55 -17.27
Golgi 6.86 15.24 0.64 -2.26 -4.06 -5.24 2.27 1.11 5.88 -2.14 -1.51 15.04 0.28 1.21 -4.03
Lipid Particles 13.39 14.07 14.76 0.49 1.21 0.49 2.96 0.52 0.24 -1.30 9.27 14.89 14.30 3.15 -0.26
Mitochondria 2.35 8.02 2.59 0.52 -2.11 -6.92 -0.06 2.26 7.30 3.70 -3.32 7.87 2.19 4.46 -2.07
Mitotic Spindle -2.55 -3.44 -5.63 -4.37 -1.93 -5.11 -3.48 -1.50 1.64 0.39 -5.64 -4.86 -5.70 -2.05 -2.11
None -0.04 -3.92 5.42 2.21 13.47 -0.84 -2.89 1.24 1.99 3.82 -0.21 -3.43 5.55 2.99 5.92
Nuclear Periphery -2.18 -21.41 -4.13 0.44 19.55 -1.36 -19.19 -1.87 -1.40 9.28 -2.59 -27.65 -4.32 -0.46 23.29
Nuclear Periphery Foci -2.01 -9.37 -3.62 -3.30 3.87 1.54 -9.20 -2.73 -2.80 -1.66 -1.40 -12.64 -3.88 -3.73 2.22
Nucleolus -4.52 -0.67 -0.33 4.29 0.39 -1.87 -1.46 -0.78 -0.08 -0.34 -5.04 -2.81 -0.29 4.69 2.39
Nucleus 5.57 -47.85 9.23 2.54 50.24 3.62 -28.35 3.38 1.13 29.33 8.30 -52.84 9.57 1.48 56.38
Peroxisomes 0.77 17.06 2.02 0.36 -8.69 -3.56 6.17 -1.62 -1.03 -2.06 -1.52 17.34 0.88 1.90 -8.27
Vacuole -36.05 15.01 -28.97 5.55 -41.31 -2.96 13.29 -1.18 0.07 -7.16 -35.17 13.13 -25.68 4.16 -38.10
Vacuole Periphery -9.76 16.31 -3.26 5.00 -11.86 -19.21 2.60 -0.73 12.71 -2.06 -18.00 10.75 -3.79 9.88 -10.06
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cell cycle-regulated gene of unknown function; promoter bound by Fkh2p; null mutant is sensitive to expression of the top1-T722A allele; TDA7 has a paralog, YDL211C, that arose from the whole genome duplication
Localization
Cell Percentages vacuole (44%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Tda7

Tda7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tda7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available