Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0 0 0 0 0 0
Cytoplasm 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0.08 0.1 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0
Endosome 0.05 0.07 0.08 0 0.06 0.07 0.05 0 0 0 0 0 0.15 0.19 0.19 0.21 0.18 0.1 0.08 0.07 0 0.05 0.06 0.09
Golgi 0 0 0.11 0.11 0 0 0 0 0 0 0 0 0.16 0.15 0.09 0 0.07 0.09 0.05 0 0 0.06 0.05 0.06
Mitochondria 0.87 0.86 0.8 0.87 0.87 0.81 0.82 0.82 0.94 0.91 0.9 0.92 0.63 0.53 0.55 0.11 0.07 0.1 0.79 0.76 0.78 0.74 0.66 0.61
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0.07 0.07 0.1 0.1 0.1 0.09 0.09 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.08 0 0.05 0.05 0.05 0.09 0.06 0.05 0.1 0.08 0.06 0.05 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0
Peroxisomes 0 0.07 0.07 0 0 0 0 0 0 0 0 0 0.24 0.3 0.32 0.29 0.27 0.22 0 0 0.09 0.05 0.1 0.11
SpindlePole 0.05 0 0.08 0 0 0 0 0 0 0 0 0 0.11 0.17 0.13 0.21 0.23 0.24 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.2 0.06 0 0.11 0.11 0.11 0.09 0 0.05 0.05 0.05 0.08 0.08 0.08 0.11 0.16 0.21 0 0.05 0 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 1 3 2 1 0 0 0 0 0 1 0 5 1 3 1 1 2 0 7 3 4 11 10
Bud 2 14 0 2 10 2 6 0 5 11 10 8 9 10 8 8 9 2 0 2 0 0 2 1
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 2 1 0 1 1
Bud Site 0 2 0 0 2 0 2 0 4 2 2 6 0 0 1 3 4 1 – – – – – –
Cell Periphery 1 37 5 2 0 3 3 5 1 4 5 3 8 8 14 4 21 14 0 0 0 0 0 0
Cytoplasm 3 14 2 8 3 4 5 3 2 3 9 2 11 9 10 12 28 18 0 2 0 1 2 3
Endoplasmic Reticulum 1 10 2 3 1 3 2 0 1 1 7 8 0 1 4 10 6 7 0 2 0 0 1 1
Endosome 7 47 11 0 10 18 20 10 0 5 7 7 77 88 90 32 52 21 10 46 5 17 23 28
Golgi 3 13 16 15 2 9 11 7 1 3 3 6 84 72 43 3 20 18 6 28 5 21 17 20
Mitochondria 114 565 115 116 147 216 302 183 304 288 383 519 320 247 263 17 20 21 106 520 128 265 250 205
Nucleus 3 5 0 2 1 2 6 0 0 2 3 0 2 3 2 6 7 7 0 1 0 1 0 1
Nuclear Periphery 3 9 1 4 11 18 36 23 32 28 39 50 5 1 4 3 12 7 2 4 1 3 4 2
Nucleolus 10 13 7 7 9 25 22 11 34 24 24 31 15 7 10 7 13 10 0 1 1 1 0 0
Peroxisomes 1 48 10 1 1 2 2 2 0 7 0 8 121 142 154 44 76 44 3 21 14 17 36 36
SpindlePole 7 20 11 2 2 4 5 5 4 6 3 5 57 78 63 31 64 48 2 3 1 4 7 6
Vac/Vac Membrane 13 134 9 4 19 29 40 20 4 17 22 31 41 38 37 17 46 43 1 33 0 16 13 10
Unique Cell Count 131 659 143 134 169 268 367 224 325 318 425 565 511 469 482 150 284 201 134 682 166 359 378 337
Labelled Cell Count 170 932 192 168 219 335 462 269 393 401 518 684 755 705 706 200 379 263 134 682 166 359 378 337


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.8 6.0 7.3 8.1 6.7 7.7 7.6 7.8 6.7 7.4 7.2 7.2 8.2 7.7 7.3 5.9 8.0 7.5 8.2 8.7 8.7
Std Deviation (1e-4) 1.3 1.6 1.3 1.6 1.4 1.6 1.4 1.4 1.5 1.7 1.7 1.6 1.6 1.3 1.5 1.4 1.9 1.7 1.7 2.0 2.0
Intensity Change (Log2) – – – 0.15 -0.12 0.07 0.07 0.1 -0.13 0.02 -0.03 -0.01 0.17 0.07 0.0 -0.3 0.14 0.03 0.18 0.25 0.26

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1.6 1.4
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 2.6 3.2 3.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.3 0 0
Endosome -3.3 -0.6 -0.4 -1.0 -1.3 0 0 0 0 2.3 3.1 3.1 3.3 2.9 0.9
Golgi 0 -3.8 -3.2 -3.7 -3.1 -5.8 -5.1 0 0 1.5 1.2 -0.8 -3.2 -1.5 -0.7
Mitochondria 1.4 1.6 0 0.5 0.3 4.3 3.0 3.1 4.0 -4.0 -5.9 -5.6 -11.9 -15.4 -13.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 2.7 2.8 3.6 3.6 3.6 3.3 3.4 3.4 0 0 0 0 0 0
Nucleolus 0.1 0.2 1.6 0.5 0 2.0 1.1 0.3 0.3 0 0 0 -0.1 -0.1 0
Peroxisomes -2.7 -3.1 0 0 0 0 -2.5 0 0 4.4 5.6 6.0 4.9 4.8 3.7
SpindlePole -2.4 -2.9 -3.2 0 -2.5 0 -3.1 0 0 1.2 2.7 1.7 3.2 3.8 3.9
Vacuole -1.3 1.5 1.5 1.6 0.9 0 -0.4 -0.5 -0.4 0.7 0.7 0.6 1.5 2.9 3.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.7938 12.801 12.6271 12.9458 11.4199 12.9249 15.8177 16.661 15.9858 15.0563 14.3772 16.0162 10.6358 11.5751 11.2305 10.1603 10.4051 11.4766
Actin 0.0346 0.0024 0.024 0.0003 0.014 0.0148 0.0223 0.0028 0.0105 0.0108 0.0002 0.0018 0.0339 0.0044 0.0068 0.0044 0.0054 0.0003
Bud 0.0005 0.0001 0.0002 0.0001 0.0004 0.0001 0.0003 0.0001 0.0001 0.0001 0 0 0.0003 0.0002 0.001 0.0002 0.0001 0
Bud Neck 0.0008 0 0.0005 0 0.0004 0.0002 0.0003 0.0001 0.0001 0.0001 0 0 0.0025 0.0001 0.0003 0.0001 0.0001 0
Bud Periphery 0.001 0.0002 0.0003 0.0007 0.0009 0.0001 0.0006 0.0002 0.0003 0.0002 0.0002 0.0001 0.0007 0.0009 0.0017 0.0007 0.0003 0.0001
Bud Site 0.0059 0.0001 0.0014 0 0.0009 0.0001 0.0009 0.0005 0.0007 0.0002 0 0.0001 0.0065 0.0006 0.0032 0.0001 0.0003 0
Cell Periphery 0.0007 0.0001 0.0001 0.0003 0.0003 0.0001 0.0002 0.0003 0.0001 0.0001 0 0.0001 0.0004 0.0014 0.0005 0.0001 0.0001 0
Cytoplasm 0.0037 0 0.0011 0 0.0001 0 0.001 0 0.0029 0.0002 0 0 0.0006 0.0001 0.0022 0.0001 0.0001 0
Cytoplasmic Foci 0.0068 0.0017 0.008 0.0002 0.0129 0.0015 0.0069 0.0015 0.005 0.0044 0 0.0011 0.01 0.0016 0.0063 0.0004 0.0031 0.0001
Eisosomes 0.0007 0.0002 0.0004 0.0001 0.0003 0.0003 0.0006 0.0001 0.0002 0.0002 0.0001 0.0003 0.0012 0.0002 0.0004 0.0003 0.0002 0.0001
Endoplasmic Reticulum 0.0022 0 0.0007 0.0001 0.0002 0 0.0012 0 0.0004 0.0008 0 0.0001 0.0014 0.0001 0.0003 0.003 0.0001 0
Endosome 0.0106 0.0023 0.0051 0.0043 0.0292 0.0025 0.0087 0.0032 0.0067 0.0105 0.0001 0.0024 0.0178 0.0026 0.0032 0.0063 0.0032 0.0006
Golgi 0.0061 0.0109 0.0058 0.0017 0.0257 0.006 0.0079 0.0114 0.0121 0.026 0.0002 0.0091 0.0105 0.003 0.0028 0.0022 0.0041 0.0027
Lipid Particles 0.0336 0.0142 0.012 0.0012 0.0538 0.0095 0.0163 0.0034 0.0131 0.0097 0.0002 0.004 0.0384 0.0063 0.0075 0.0044 0.0189 0.002
Mitochondria 0.853 0.9545 0.9199 0.9576 0.804 0.9505 0.8998 0.9582 0.9174 0.9311 0.9981 0.9707 0.8416 0.9637 0.9261 0.9419 0.9298 0.9903
None 0.0035 0 0.0008 0 0.0002 0 0.001 0 0.0004 0.0002 0 0.0001 0.0017 0.0001 0.0084 0.0005 0.0004 0
Nuclear Periphery 0.0041 0.0002 0.0023 0.0001 0.0003 0.0001 0.0084 0 0.0057 0.0011 0 0.0005 0.0047 0.0025 0.0004 0.0284 0.0002 0.0001
Nucleolus 0.0012 0.0004 0.0002 0 0.002 0 0.0004 0.0011 0.0007 0 0 0.0001 0.0007 0.0003 0.0018 0.0003 0.0003 0.0001
Nucleus 0.0018 0.0001 0.0009 0.0001 0.0006 0 0.0041 0.0002 0.0062 0.0001 0 0 0.0009 0.0002 0.0009 0.0011 0.0002 0
Peroxisomes 0.0154 0.0084 0.0127 0.0061 0.0228 0.0101 0.0058 0.0085 0.0126 0.0026 0.0003 0.0028 0.015 0.0059 0.011 0.0005 0.0248 0.001
Punctate Nuclear 0.0034 0 0.0011 0 0.0008 0 0.0064 0 0.003 0.0003 0 0 0.0032 0 0.0022 0.0009 0.0004 0
Vacuole 0.0031 0.0008 0.0005 0.0075 0.0156 0.0005 0.0015 0.0048 0.0005 0.0003 0.0001 0.0003 0.0021 0.0022 0.0054 0.0009 0.0012 0.0002
Vacuole Periphery 0.0072 0.0033 0.0021 0.0194 0.0147 0.0035 0.0056 0.0035 0.0013 0.001 0.0004 0.0061 0.0059 0.004 0.0076 0.0032 0.0068 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.9156 11.6668 34.6291 30.3789 20.7669 34.3882 26.2736 34.3801 39.8593 33.5575
Translational Efficiency 1.8637 3.5439 1.1426 1.559 1.9657 1.5803 1.7477 1.6023 1.3717 1.6915

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1271 1270 1298 1574 1883 1728 184 765 3154 2998 1482 2339

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 914.19 951.55 1096.46 1057.37 863.59 1009.05 1056.96 1084.89 883.98 984.69 1091.56 1066.37
Standard Deviation 128.69 152.20 196.58 175.11 133.55 160.54 154.61 186.69 133.93 159.61 192.31 179.44
Intensity Change Log 2 — 0.057785 0.262287 0.209914 — 0.224579 0.291502 0.329130 — 0.141218 0.276553 0.269057

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000832 0.004687 0.003203 0.004103 0.001513 0.002671 0.003523 0.015776 0.001239 0.003525 0.003243 0.007921
Bud Neck 0.000815 0.001059 0.003050 0.001741 0.000288 0.000975 0.011406 0.003195 0.000501 0.001011 0.004087 0.002216
Bud Site 0.003315 0.001738 0.005344 0.009993 0.000711 0.002580 0.025630 0.014881 0.001760 0.002223 0.007863 0.011592
Cell Periphery 0.000522 0.000181 0.000157 0.000413 0.000087 0.000187 0.000438 0.001436 0.000263 0.000184 0.000192 0.000747
Cytoplasm 0.001607 0.000576 0.000975 0.001488 0.000212 0.000351 0.001851 0.001652 0.000774 0.000446 0.001084 0.001542
Cytoplasmic Foci 0.016025 0.022216 0.021021 0.015665 0.013369 0.015622 0.044227 0.016387 0.014439 0.018415 0.023902 0.015901
Eisosomes 0.000046 0.000135 0.000161 0.000076 0.000051 0.000073 0.000111 0.000252 0.000049 0.000099 0.000155 0.000134
Endoplasmic Reticulum 0.000536 0.000283 0.000183 0.000920 0.000147 0.000184 0.001164 0.001234 0.000304 0.000226 0.000305 0.001023
Endosome 0.028535 0.020776 0.013458 0.023406 0.012041 0.026247 0.066881 0.023897 0.018688 0.023929 0.020091 0.023567
Golgi 0.032575 0.043366 0.028552 0.061894 0.023157 0.026362 0.031205 0.052776 0.026952 0.033565 0.028881 0.058912
Lipid Particles 0.006490 0.005571 0.004416 0.001660 0.005894 0.006947 0.010326 0.000918 0.006134 0.006364 0.005150 0.001417
Mitochondria 0.864629 0.866943 0.871832 0.827463 0.922846 0.886463 0.666840 0.820355 0.899386 0.878194 0.846381 0.825138
Mitotic Spindle 0.001476 0.001961 0.006555 0.010731 0.000846 0.000877 0.042451 0.009696 0.001100 0.001336 0.011012 0.010392
None 0.000365 0.000397 0.000651 0.000451 0.000335 0.000218 0.000504 0.000557 0.000347 0.000294 0.000632 0.000486
Nuclear Periphery 0.000334 0.000105 0.000691 0.000382 0.000205 0.000105 0.001321 0.000185 0.000257 0.000105 0.000769 0.000318
Nuclear Periphery Foci 0.000422 0.000185 0.000890 0.000361 0.000185 0.000197 0.002255 0.000237 0.000280 0.000192 0.001059 0.000320
Nucleolus 0.000091 0.000250 0.000854 0.000158 0.000064 0.000147 0.000609 0.000670 0.000075 0.000190 0.000823 0.000326
Nucleus 0.000108 0.000197 0.000329 0.000079 0.000037 0.000087 0.000497 0.000285 0.000065 0.000133 0.000350 0.000146
Peroxisomes 0.009494 0.023023 0.018925 0.007763 0.010584 0.022304 0.060637 0.016336 0.010145 0.022609 0.024104 0.010567
Vacuole 0.011189 0.003287 0.009917 0.013304 0.002121 0.003579 0.016703 0.011852 0.005775 0.003455 0.010759 0.012829
Vacuole Periphery 0.020593 0.003064 0.008838 0.017949 0.005305 0.003826 0.011418 0.007422 0.011466 0.003503 0.009158 0.014506

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.50 -3.43 -4.75 0.69 -0.94 -1.65 -2.28 -5.34 -4.81 -4.41 -4.95 -3.18 -6.65 -4.11 -4.05
Bud Neck -0.82 -3.41 -2.46 -1.87 1.76 -3.30 -5.08 -5.20 -3.85 3.62 -2.96 -5.79 -5.69 -3.89 2.68
Bud Site 1.52 -1.35 -4.13 -6.08 -2.71 -2.24 -3.48 -5.97 -5.00 1.38 -0.72 -4.28 -7.89 -7.46 -2.18
Cell Periphery 2.16 2.33 0.66 -3.61 -4.17 -4.50 -3.31 -2.74 -2.54 -1.98 1.21 1.06 -2.74 -3.38 -3.33
Cytoplasm 1.61 0.94 0.13 -2.93 -1.46 -1.89 -4.06 -5.85 -5.19 0.40 1.26 -0.96 -2.28 -4.85 -1.64
Cytoplasmic Foci -2.77 -2.18 0.19 3.10 2.46 -1.34 -4.55 -1.39 -0.36 4.02 -2.93 -4.66 -1.12 1.76 3.86
Eisosomes -6.53 -5.45 -3.56 4.76 4.19 -3.83 -4.67 -5.53 -4.91 -3.68 -7.58 -5.95 -6.60 -2.53 0.99
Endoplasmic Reticulum 2.76 4.11 -1.40 -2.38 -2.77 -1.01 -2.79 -3.18 -3.06 -0.13 1.80 -0.04 -3.39 -3.78 -3.31
Endosome 2.86 6.28 1.93 -1.10 -4.79 -6.67 -6.78 -4.63 0.80 5.16 -3.13 -0.75 -2.86 0.17 -1.70
Golgi -2.74 1.12 -6.40 -3.77 -7.21 -1.20 -1.66 -5.83 -5.26 -3.34 -2.91 -0.69 -9.46 -7.37 -7.91
Lipid Particles 0.55 1.42 3.49 3.86 4.61 -0.82 -1.36 5.82 6.09 2.93 -0.22 1.00 6.17 6.84 5.78
Mitochondria -0.24 -0.73 3.82 3.98 4.42 5.17 9.48 9.12 5.68 -5.36 3.68 6.53 10.54 7.28 2.32
Mitotic Spindle -1.14 -3.92 -6.56 -6.12 -2.27 -0.15 -4.87 -4.68 -4.68 3.75 -1.10 -6.30 -8.22 -8.00 0.27
None -0.22 -2.25 -0.67 -1.16 5.77 4.41 -2.74 -4.02 -6.72 -0.71 1.00 -4.93 -2.47 -6.78 4.41
Nuclear Periphery 3.00 -2.22 -0.42 -2.85 1.78 1.67 -3.92 0.26 -1.58 4.01 3.22 -3.71 -0.79 -3.19 3.08
Nuclear Periphery Foci 2.61 -1.17 0.53 -2.33 1.32 -0.19 -2.85 -0.65 -0.54 2.77 1.67 -2.19 -0.68 -2.33 2.06
Nucleolus -1.40 -2.48 -1.15 0.64 2.19 -1.28 -3.48 -1.09 -0.94 -0.14 -1.90 -2.78 -1.37 -0.74 1.45
Nucleus -0.83 -1.72 0.64 1.06 1.93 -1.46 -3.39 -1.24 -0.99 0.81 -1.37 -2.55 -1.25 -0.24 1.50
Peroxisomes -4.73 -3.54 0.88 5.62 4.46 -4.66 -4.80 -2.21 1.90 4.18 -6.60 -5.53 -0.29 6.13 5.24
Vacuole 5.18 0.69 -1.12 -6.56 -1.92 -2.65 -5.23 -4.48 -3.82 1.37 3.30 -4.12 -5.34 -7.67 -1.36
Vacuole Periphery 9.84 5.80 1.12 -9.29 -4.87 1.95 -2.62 -2.12 -4.26 1.69 9.28 1.85 -2.24 -9.83 -3.73
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit
Localization
Cell Percentages mitochondrion (99%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrpl22

Mrpl22


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrpl22-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available