Standard name
Human Ortholog
Description Histone chaperone; involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition; interacts physically and functionally with Chromatin Assembly Factor-1 (CAF-1)
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.05 0.09 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.08 0 0 0 0 0 0 0 0 0.1 0.14 0.15 0.06 0.1 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.2 0.07 0.05 0.07 0.09 0.27 0.35 0.22 0.29 0.37 0.47 0.44 0 0 0 0 0 0.05 0 0 0 0 0 0
Nucleus 0.94 0.95 0.96 0.9 0.89 0.82 0.81 0.77 0.77 0.76 0.73 0.74 0.89 0.84 0.79 0.85 0.86 0.86 0.96 0.93 0.94 0.89 0.77 0.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.09 0.12 0.13 0.18 0.15 0.2 0.21 0.18 0 0 0 0 0 0 0 0 0 0 0.05 0.05
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0.06 0.13 0.19
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 3 8 5 2 4 2 11 1 0 0 0 0 0 0 0 3 1 1 0
Bud Neck 0 0 0 0 0 1 0 1 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 1 1 9 10 23 22 34 45 38 1 1 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 5 7 19 10 14 19 15 11 12 6 11 34 47 66 8 21 12 0 0 0 1 1 0
Endoplasmic Reticulum 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 3 2 0 0 0 0 0 0
Endosome 0 0 0 0 0 1 0 1 0 0 0 0 1 0 1 2 1 1 0 5 1 1 2 4
Golgi 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 1
Mitochondria 37 31 22 16 26 146 255 145 153 252 242 306 2 1 2 0 7 7 1 6 0 0 2 4
Nucleus 173 442 437 213 255 441 589 509 411 519 374 518 314 284 341 114 177 115 175 447 426 190 220 221
Nuclear Periphery 0 0 4 1 5 5 15 9 11 15 9 5 4 1 4 1 2 0 0 0 0 0 0 2
Nucleolus 3 9 10 9 26 67 98 118 83 136 106 126 2 3 3 2 4 2 0 3 3 1 13 15
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 0 3 1 2 2 2 2 15 1 0 0 1 0 0 1 0 3
Vac/Vac Membrane 1 3 2 1 0 2 9 3 6 7 3 7 3 7 7 10 2 2 1 11 12 13 37 60
Unique Cell Count 184 465 455 237 285 541 728 657 536 683 512 696 353 337 430 134 207 133 182 479 454 213 285 319
Labelled Cell Count 216 490 484 261 323 689 1004 829 702 981 789 1026 364 346 443 141 217 141 182 479 454 213 285 319


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 7.3 6.5 6.5 6.3 5.0 4.9 5.1 4.9 4.6 4.2 4.1 8.5 8.0 7.6 9.4 8.4 8.8 8.3 8.9 9.1
Std Deviation (1e-4) 1.0 1.6 1.2 2.2 1.9 1.5 1.4 1.5 1.4 1.3 1.2 1.1 3.1 1.9 1.9 2.1 2.0 2.3 1.6 1.9 1.7
Intensity Change (Log2) – – – 0.0 -0.05 -0.37 -0.42 -0.37 -0.41 -0.51 -0.63 -0.66 0.38 0.29 0.21 0.53 0.36 0.43 0.34 0.44 0.48


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 4.0 4.4 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4.3 1.7 1.1 1.2 0.9 0.6 0.3 -0.5 0.1 5.2 6.8 7.5 0 5.1 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.0 2.3 9.3 0 7.9 9.8 0 0 0 -3.5 -3.8 -4.0 -2.6 -0.8 0.2
Nucleus -3.2 -3.5 -7.1 -7.5 -8.5 -8.6 -9.0 -9.7 -9.5 -3.9 -5.7 -7.6 -4.5 -4.8 -4.1
Nuclear Periphery 0 0 0 0 0.7 1.5 0 0 0 0 0 0 0 0 0
Nucleolus 1.2 4.3 6.0 0 8.1 7.1 0 0 0 -1.9 -1.4 -1.9 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 4.0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.515 7.7706 7.6386 6.8685 6.3819 6.8804 5.2228 6.3088 5.7746 5.2373 5.5571 5.5028 6.3504 6.7061 6.5603 6.1105 5.6976 5.907
Actin 0.0007 0 0 0 0.0006 0 0.02 0 0.0034 0.0013 0.0019 0.0021 0.0076 0 0.0001 0 0 0.0003
Bud 0 0 0 0 0 0 0.0008 0 0.0011 0.0001 0.0016 0.0001 0.0001 0 0 0 0 0
Bud Neck 0.0001 0 0 0 0.0001 0.0003 0.0009 0 0.0003 0.0004 0.0009 0.0006 0.0005 0 0.0001 0 0.0003 0.0003
Bud Periphery 0.0001 0 0 0 0 0 0.0019 0 0.0022 0.0004 0.0051 0.0002 0.0004 0 0.0001 0 0 0.0001
Bud Site 0.0001 0 0 0 0 0 0.002 0 0.001 0.0003 0.0029 0.0002 0.0005 0 0.0001 0 0.0001 0
Cell Periphery 0 0 0 0 0 0 0.0008 0 0.0003 0.0001 0.0024 0.0001 0.0002 0 0.0001 0 0 0
Cytoplasm 0.0019 0.0003 0 0 0 0 0.0076 0 0.0007 0.0035 0.003 0.0001 0.0002 0 0.0002 0 0.0004 0
Cytoplasmic Foci 0.009 0 0 0 0.0005 0 0.007 0 0.0043 0.0262 0.0039 0.0029 0.0006 0 0.0003 0 0.0001 0
Eisosomes 0 0 0 0 0 0 0.0001 0 0 0 0.0001 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0014 0 0 0 0 0 0.0028 0 0.0008 0.0025 0.003 0.0001 0.0002 0 0.0001 0 0.0001 0.0002
Endosome 0.0065 0.0002 0 0 0.0001 0 0.0184 0 0.0026 0.0226 0.0346 0.002 0.0005 0 0.0002 0 0.0001 0.0005
Golgi 0.0007 0 0 0 0.0003 0 0.0069 0 0.0029 0.0082 0.0047 0.0033 0.0004 0 0 0 0 0
Lipid Particles 0.0069 0 0 0 0.0031 0 0.0095 0 0.0019 0.0332 0.0102 0.0027 0.0017 0 0.0008 0 0.0001 0.0001
Mitochondria 0.0005 0.0002 0.0002 0 0.0111 0.0001 0.0134 0.0001 0.0056 0.0041 0.0492 0.0033 0.0015 0.0001 0.0004 0 0.0001 0.0003
None 0.0191 0 0 0 0 0 0.0042 0 0.0003 0.0007 0.0005 0.0001 0.0002 0 0.0001 0 0.0002 0.0001
Nuclear Periphery 0.0231 0.0049 0.0053 0.0003 0.0022 0.0002 0.0177 0.0006 0.0106 0.0166 0.0078 0.0005 0.0018 0.001 0.0019 0.0003 0.0009 0.0036
Nucleolus 0.0118 0.0113 0.007 0.005 0.0408 0.0389 0.0232 0.0068 0.0095 0.0103 0.0492 0.0418 0.0204 0.0084 0.0161 0.0026 0.0535 0.0259
Nucleus 0.8888 0.9726 0.9872 0.9944 0.903 0.9601 0.823 0.9923 0.9431 0.8534 0.7722 0.9364 0.9594 0.9903 0.9778 0.9971 0.9273 0.9678
Peroxisomes 0.0004 0 0 0 0.037 0 0.0112 0 0.0008 0.0063 0.0024 0.002 0.0004 0 0 0 0 0
Punctate Nuclear 0.0277 0.0001 0.0001 0.0003 0.0009 0.0001 0.0161 0.0001 0.0065 0.0062 0.0009 0.0004 0.0017 0 0.0006 0 0.0166 0.0002
Vacuole 0.0006 0.0056 0 0 0 0.0001 0.0098 0 0.001 0.0022 0.0353 0.0007 0.001 0 0.0005 0 0.0001 0.0003
Vacuole Periphery 0.0006 0.0047 0.0001 0 0.0001 0 0.003 0 0.001 0.0015 0.0082 0.0005 0.0006 0 0.0005 0 0 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 49.2015 20.189 28.3571 28.1161 49.1511 34.6638 25.8808 21.4042 26.3268 37.1786
Translational Efficiency 0.8857 0.9662 0.6587 0.9365 0.7356 1.1944 0.6987 0.8075 0.761 0.835

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1914 610 2334 805 890 1843 124 885 2804 2453 2458 1690

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 738.10 955.63 1047.58 1036.45 801.62 882.03 1071.84 1016.11 758.26 900.33 1048.80 1025.80
Standard Deviation 107.18 156.42 147.62 196.68 117.69 138.09 128.13 157.74 114.51 146.37 146.80 177.65
Intensity Change Log 2 — 0.372636 0.505172 0.489762 — 0.137909 0.419099 0.342066 — 0.255202 0.461001 0.414756

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000288 0.000498 0.000438 0.000886 0.000230 0.000422 0.000784 0.001349 0.000269 0.000441 0.000455 0.001128
Bud Neck 0.004006 0.007289 0.016787 0.014073 0.003150 0.009013 0.003786 0.028614 0.003734 0.008584 0.016131 0.021688
Bud Site 0.000827 0.000813 0.000834 0.001911 0.000332 0.001703 0.000708 0.011003 0.000670 0.001481 0.000828 0.006672
Cell Periphery 0.000185 0.000181 0.000096 0.000055 0.000281 0.000258 0.000068 0.000271 0.000215 0.000239 0.000094 0.000168
Cytoplasm 0.002854 0.000440 0.000226 0.002837 0.000464 0.000523 0.000651 0.013186 0.002095 0.000502 0.000247 0.008256
Cytoplasmic Foci 0.001179 0.000243 0.000004 0.000117 0.000046 0.000648 0.000655 0.005926 0.000819 0.000547 0.000037 0.003159
Eisosomes 0.000025 0.000039 0.000053 0.000026 0.000025 0.000038 0.000050 0.000037 0.000025 0.000038 0.000053 0.000032
Endoplasmic Reticulum 0.006546 0.006520 0.003100 0.003776 0.005085 0.007187 0.004760 0.006239 0.006082 0.007022 0.003184 0.005066
Endosome 0.000676 0.000389 0.000076 0.000282 0.000151 0.001165 0.000706 0.007421 0.000509 0.000972 0.000108 0.004020
Golgi 0.000585 0.000252 0.000022 0.000267 0.000027 0.000415 0.000119 0.003619 0.000408 0.000375 0.000027 0.002022
Lipid Particles 0.000169 0.000062 0.000010 0.000059 0.000064 0.000779 0.000724 0.001959 0.000136 0.000601 0.000046 0.001054
Mitochondria 0.001448 0.003155 0.001233 0.003304 0.000397 0.002788 0.002516 0.007312 0.001114 0.002879 0.001298 0.005403
Mitotic Spindle 0.000662 0.003212 0.000267 0.009073 0.000351 0.002748 0.001028 0.047569 0.000564 0.002864 0.000306 0.029232
None 0.005752 0.001726 0.000616 0.002416 0.002016 0.001657 0.002811 0.007014 0.004566 0.001674 0.000727 0.004824
Nuclear Periphery 0.000616 0.000316 0.000282 0.000789 0.000424 0.000547 0.000177 0.003150 0.000555 0.000490 0.000277 0.002025
Nuclear Periphery Foci 0.000564 0.000408 0.000026 0.000384 0.000289 0.000629 0.000243 0.001944 0.000477 0.000574 0.000037 0.001201
Nucleolus 0.018689 0.010392 0.004939 0.006435 0.008912 0.009981 0.009549 0.006639 0.015586 0.010083 0.005172 0.006542
Nucleus 0.952904* 0.962778* 0.970013* 0.950861* 0.977187* 0.956630* 0.967250* 0.827217* 0.960611* 0.958159* 0.969874* 0.886112*
Peroxisomes 0.000291 0.000444 0.000093 0.000214 0.000164 0.000684 0.002034 0.001113 0.000251 0.000624 0.000190 0.000685
Vacuole 0.001200 0.000620 0.000673 0.001616 0.000309 0.001611 0.001120 0.014365 0.000917 0.001365 0.000696 0.008292
Vacuole Periphery 0.000535 0.000222 0.000212 0.000618 0.000097 0.000575 0.000262 0.004055 0.000396 0.000487 0.000215 0.002418

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.38 -4.71 -7.31 -5.02 -5.56 -4.35 -5.42 -13.37 -10.89 -4.59 -4.43 -7.07 -14.35 -11.54 -11.33
Bud Neck -3.48 -16.12 -9.79 -5.98 0.84 -5.93 -0.99 -10.33 -7.99 -9.20 -6.82 -16.61 -13.30 -9.49 -4.02
Bud Site 0.15 -0.30 -1.44 -1.51 -1.38 -3.64 -1.46 -5.96 -4.85 -5.53 -2.59 -1.33 -5.84 -4.67 -5.58
Cell Periphery 0.09 3.73 5.57 2.69 2.94 0.12 1.13 0.45 1.02 -2.71 -0.32 1.98 1.33 2.47 -1.70
Cytoplasm 4.24 4.57 0.36 -1.87 -2.04 -0.29 -0.46 -6.64 -6.62 -6.43 4.03 4.60 -4.83 -6.64 -6.84
Cytoplasmic Foci 2.62 3.37 3.12 0.94 -2.11 -2.61 -1.32 -3.74 -2.92 -2.72 1.28 3.31 -1.39 -2.45 -3.82
Eisosomes -4.00 -10.67 -1.76 3.20 9.83 -3.13 -3.72 -4.33 -1.59 1.35 -5.74 -10.67 -5.73 1.19 6.88
Endoplasmic Reticulum 0.04 9.21 6.30 3.35 -4.07 -4.24 0.27 -3.89 0.08 -4.18 -2.28 10.02 1.23 3.57 -10.00
Endosome 1.68 4.03 2.65 0.60 -2.45 -3.74 -0.89 -4.82 -3.40 -3.48 -1.65 3.84 -3.79 -2.73 -4.99
Golgi 1.16 2.06 1.29 0.24 -1.73 -3.28 -1.29 -2.50 -1.97 -2.38 0.24 2.04 -1.54 -1.80 -2.70
Lipid Particles 2.97 4.44 2.31 -0.77 -2.96 -1.63 -1.08 -2.47 -0.62 -0.69 -1.36 2.64 -2.12 -0.13 -2.57
Mitochondria -0.97 0.35 -1.58 0.00 -1.84 -3.92 -1.18 -4.54 -2.08 -1.45 -2.59 -0.70 -4.05 -1.49 -3.88
Mitotic Spindle -1.49 0.07 -2.79 -1.45 -2.80 -2.44 -0.48 -6.84 -6.32 -6.67 -2.78 -0.16 -7.31 -6.32 -7.29
None 3.99 5.61 3.60 -0.76 -3.98 0.56 -0.49 -2.60 -3.13 -1.55 4.15 5.81 0.69 -3.22 -4.81
Nuclear Periphery 1.32 1.45 -1.30 -2.55 -2.71 -0.40 0.92 -2.54 -2.50 -2.97 0.39 1.46 -2.76 -3.03 -3.46
Nuclear Periphery Foci 0.56 3.20 -0.13 -0.49 -1.62 -0.90 0.38 -2.74 -1.69 -3.35 -0.28 3.34 -1.75 -1.29 -4.00
Nucleolus 3.73 10.31 7.75 1.70 -1.60 -0.60 -0.40 1.26 2.08 1.33 4.64 10.14 7.90 2.80 -2.30
Nucleus -1.92 -5.00 0.81 2.26 4.20 5.36 1.23 13.82 11.28 9.56 0.58 -3.07 11.21 10.45 12.99
Peroxisomes -0.51 2.88 1.48 1.44 -4.14 -3.17 -1.18 -3.25 -0.03 0.83 -2.35 1.11 -1.62 1.06 -2.45
Vacuole 2.09 1.23 -1.36 -3.01 -2.35 -3.43 -2.32 -7.54 -6.81 -7.04 -1.19 0.49 -7.34 -6.87 -7.42
Vacuole Periphery 2.24 2.03 0.04 -1.10 -1.05 -3.46 -0.83 -3.17 -2.41 -2.84 -0.64 1.45 -2.64 -2.39 -3.11
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone chaperone; involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition; interacts physically and functionally with Chromatin Assembly Factor-1 (CAF-1)
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Rtt106

Rtt106


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rtt106-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available