Standard name
Human Ortholog
Description Phosphatidylinositol transfer protein (PITP); downregulates Plb1p-mediated turnover of phosphatidylcholine; forms a complex with Psd2p which appears essential for maintenance of vacuolar PE levels; found in the cytosol and microsomes; homologous to Pdr16p; deletion affects phospholipid composition
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.07 0.05 0.09 0.15 0.05 0.05 0 0 0 0 0 0 0.07 0.22 0.2 0.38 0.82 0.53 0.05 0 0.05 0.08 0.09 0.05
Cytoplasm 0.97 0.98 0.99 0.97 0.99 0.9 0.89 0.92 0.87 0.86 0.83 0.87 1.0 0.99 0.99 0.9 0.94 0.83 0.83 0.88 0.84 0.84 0.81 0.81
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.14 0.09 0.24 0.2 0.26 0.24 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 1 2 0 1 1 1 1 2 0 0 0 0 0 0 0 0 8 1 2 4 7 8
Bud 3 1 0 0 0 1 6 3 7 9 8 2 0 0 0 0 0 0 0 1 1 0 1 5
Bud Neck 0 0 2 1 1 2 0 3 0 2 0 1 0 0 1 0 0 0 5 3 3 3 9 7
Bud Site 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 17 8 13 31 15 12 5 7 8 4 8 3 14 41 41 48 14 54 14 3 7 16 31 15
Cytoplasm 252 144 145 207 275 213 297 244 231 261 171 152 204 188 205 114 16 84 216 130 125 163 281 273
Endoplasmic Reticulum 4 2 0 1 1 2 0 4 2 1 1 1 2 0 0 3 0 3 3 1 0 1 5 8
Endosome 0 0 0 1 0 1 3 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 2 2
Golgi 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 3 0 0 0 0 0 0 1 0
Mitochondria 4 0 0 2 4 11 46 24 64 60 53 42 0 0 1 1 0 1 1 0 3 1 2 5
Nucleus 0 1 0 0 1 0 2 0 2 2 0 2 0 0 1 3 1 1 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 1 11 12 0 1 2 1 3 0 0 0 2 0 3 0 3 0 0 0 0
Unique Cell Count 261 147 146 213 278 236 332 264 267 305 206 175 205 190 207 127 17 101 261 148 150 195 347 336
Labelled Cell Count 282 156 162 248 298 259 373 287 316 344 243 207 220 230 249 175 31 146 261 148 150 195 347 336


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 6.6 6.1 6.1 5.9 5.1 4.6 4.9 4.3 4.2 4.2 4.5 6.5 7.2 7.1 10.9 9.5 10.6 6.2 6.5 6.8
Std Deviation (1e-4) 0.5 1.3 1.1 1.5 1.7 1.5 1.4 1.2 1.6 1.1 1.7 1.2 1.0 1.3 1.3 2.1 1.5 1.7 1.2 1.2 1.5
Intensity Change (Log2) – – – 0.0 -0.03 -0.26 -0.42 -0.32 -0.49 -0.52 -0.54 -0.43 0.1 0.24 0.21 0.84 0.64 0.8 0.03 0.09 0.15

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.6 -1.4 -1.5 0 0 0 0 0 0 -0.7 3.1 2.8 5.7 0 7.7
Cytoplasm -1.4 -0.4 -3.5 -3.8 -3.0 -4.4 -4.6 -5.0 -4.2 0.2 -0.4 -0.3 -3.6 -1.8 -4.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.2385 2.8962 2.4555 2.2814 1.8806 2.5157 0.6766 1.4581 1.2861 1.2421 0.9002 1.1557 0.8733 1.2495 0.7573 0.856 0.8071 1.2345
Actin 0.0258 0.0029 0.0191 0.0061 0.0137 0.0055 0.0213 0.0016 0.0158 0.0037 0.0083 0.0035 0.0281 0.0074 0.0243 0.0013 0.0012 0.0309
Bud 0.0011 0.0025 0.0015 0.0003 0.0011 0.0003 0.0011 0.0007 0.0085 0.0329 0.0013 0.0043 0.0036 0.0021 0.0039 0.0001 0.0002 0.003
Bud Neck 0.0016 0.0007 0.0019 0.0005 0.0013 0.0023 0.001 0.0011 0.0016 0.007 0.001 0.0033 0.0038 0.0006 0.0017 0.0004 0.0011 0.0247
Bud Periphery 0.0018 0.0023 0.0039 0.0005 0.0022 0.0007 0.0016 0.001 0.0041 0.02 0.0024 0.0032 0.008 0.0038 0.0118 0.0001 0.0002 0.0056
Bud Site 0.009 0.0273 0.008 0.0006 0.0025 0.0005 0.0072 0.0165 0.012 0.0319 0.006 0.0008 0.0064 0.007 0.0076 0.0003 0.0002 0.0111
Cell Periphery 0.0038 0.0027 0.0023 0.0008 0.0006 0.0009 0.0025 0.0021 0.0019 0.0025 0.0023 0.0015 0.0034 0.002 0.0012 0.0005 0.0006 0.0009
Cytoplasm 0.5216 0.6544 0.5552 0.6702 0.4359 0.6402 0.5559 0.6619 0.5727 0.3955 0.5078 0.7222 0.5929 0.7717 0.7742 0.7158 0.6899 0.6573
Cytoplasmic Foci 0.0136 0.0029 0.013 0.0064 0.038 0.0107 0.0174 0.0062 0.0099 0.0092 0.026 0.0063 0.012 0.0128 0.0183 0.0052 0.0285 0.0169
Eisosomes 0.0003 0.0003 0.0005 0.0003 0.0002 0.0001 0.0003 0.0003 0.0003 0.0003 0.0002 0.0001 0.0009 0.0002 0.0001 0.0001 0.0001 0.0003
Endoplasmic Reticulum 0.0045 0.0021 0.0043 0.0167 0.0043 0.003 0.0046 0.0041 0.0062 0.0075 0.0065 0.0042 0.0138 0.0087 0.0068 0.0035 0.0077 0.0053
Endosome 0.0173 0.0004 0.0104 0.0129 0.0445 0.0069 0.0086 0.0014 0.0059 0.0067 0.0478 0.0044 0.0201 0.001 0.0097 0.0091 0.07 0.0119
Golgi 0.0081 0.0003 0.0048 0.0016 0.0262 0.0025 0.002 0.0003 0.0019 0.0011 0.0138 0.0007 0.0056 0.0006 0.0111 0.011 0.006 0.0059
Lipid Particles 0.0063 0.0002 0.0046 0.0036 0.0065 0.0023 0.0055 0.0012 0.0022 0.0029 0.0123 0.0028 0.01 0.0015 0.0057 0.0478 0.0179 0.0123
Mitochondria 0.0034 0.0002 0.0026 0.0027 0.0109 0.0024 0.0033 0.0002 0.0061 0.0028 0.013 0.0009 0.0214 0.0003 0.0051 0.026 0.0013 0.0032
None 0.3596 0.2976 0.3446 0.2619 0.3835 0.3178 0.3392 0.2954 0.3181 0.4203 0.2619 0.227 0.2186 0.1604 0.0976 0.1647 0.164 0.1776
Nuclear Periphery 0.0026 0.0003 0.0007 0.0067 0.0031 0.0004 0.0124 0.0006 0.0093 0.0038 0.0324 0.0057 0.02 0.0005 0.0013 0.0003 0.0018 0.0081
Nucleolus 0.0004 0.0003 0.0014 0.0005 0.0005 0.0001 0.0005 0.0003 0.0009 0.0093 0.0006 0.0004 0.0011 0.0007 0.0002 0.0001 0.0002 0.0008
Nucleus 0.0033 0.0012 0.0016 0.0016 0.0018 0.0006 0.0041 0.0019 0.0054 0.0188 0.0041 0.0021 0.0052 0.0133 0.0007 0.0006 0.0015 0.0064
Peroxisomes 0.012 0.0002 0.0147 0.0012 0.013 0.0012 0.004 0.0003 0.0066 0.001 0.039 0.0026 0.0053 0.0041 0.0165 0.0115 0.0021 0.007
Punctate Nuclear 0.0016 0.0008 0.0019 0.0028 0.0013 0.0009 0.0053 0.0017 0.0083 0.0175 0.0046 0.0027 0.0138 0.0005 0.0005 0.0003 0.0018 0.0073
Vacuole 0.0017 0.0005 0.0025 0.0016 0.0065 0.0006 0.0013 0.001 0.0017 0.0046 0.0067 0.0009 0.0035 0.001 0.0013 0.0007 0.0031 0.0027
Vacuole Periphery 0.0006 0 0.0006 0.0006 0.0024 0.0001 0.001 0.0001 0.0007 0.0006 0.0021 0.0003 0.0024 0 0.0003 0.0004 0.0007 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 49.2498 47.7732 27.8037 32.5259 40.7582 35.6078 39.069 39.3137 35.5371 40.7239
Translational Efficiency 1.1193 1.0646 1.4145 1.3436 1.2321 1.6809 1.2935 1.2426 1.4849 1.298

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1996 170 2180 223 2011 1733 459 1488 4007 1903 2639 1711

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 795.63 917.73 894.18 1021.96 767.60 768.90 973.97 969.61 781.56 782.20 908.06 976.43
Standard Deviation 87.41 104.14 107.62 131.84 84.76 100.08 106.61 126.65 87.22 109.05 111.62 128.55
Intensity Change Log 2 — 0.205972 0.168468 0.361169 — 0.002441 0.343523 0.337050 — 0.109613 0.257080 0.349376

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001221 0.001946 0.000425 0.001714 0.000886 0.002442 0.000453 0.001008 0.001053 0.002398 0.000430 0.001100
Bud Neck 0.026562 0.016479 0.008280 0.004310 0.028063 0.036297 0.004364 0.005649 0.027315 0.034527 0.007599 0.005475
Bud Site 0.015888 0.045085 0.029924 0.037635 0.014743 0.032386 0.018002 0.044843 0.015313 0.033520 0.027850 0.043904
Cell Periphery 0.001282 0.000800 0.000339 0.000528 0.001325 0.000766 0.000546 0.000301 0.001303 0.000769 0.000375 0.000330
Cytoplasm 0.579428 0.471265 0.648870 0.329143 0.590748 0.526205 0.518830 0.558524 0.585109 0.521297 0.626252 0.528628
Cytoplasmic Foci 0.162557 0.235646 0.019214 0.051444 0.103959 0.180457 0.079748 0.036884 0.133148 0.185387 0.029743 0.038782
Eisosomes 0.002796 0.000701 0.000071 0.000187 0.002655 0.001093 0.000180 0.000106 0.002725 0.001058 0.000090 0.000117
Endoplasmic Reticulum 0.001449 0.001166 0.001410 0.003397 0.001601 0.001563 0.002299 0.001342 0.001526 0.001528 0.001565 0.001610
Endosome 0.007636 0.017668 0.001127 0.013401 0.003692 0.017968 0.004951 0.004448 0.005656 0.017941 0.001792 0.005615
Golgi 0.005758 0.002352 0.000109 0.018644 0.004027 0.006304 0.000133 0.001328 0.004890 0.005951 0.000113 0.003585
Lipid Particles 0.006856 0.002676 0.000775 0.002806 0.004474 0.005365 0.002383 0.001170 0.005661 0.005125 0.001054 0.001384
Mitochondria 0.002053 0.000481 0.000427 0.010661 0.001954 0.003998 0.000080 0.004429 0.002004 0.003684 0.000367 0.005242
Mitotic Spindle 0.000569 0.013016 0.004819 0.001912 0.000379 0.002016 0.000296 0.025220 0.000474 0.002999 0.004032 0.022182
None 0.003420 0.000265 0.001360 0.000572 0.004348 0.001093 0.001706 0.002130 0.003886 0.001019 0.001420 0.001927
Nuclear Periphery 0.000094 0.000116 0.000438 0.000544 0.000113 0.000100 0.000473 0.000520 0.000104 0.000101 0.000444 0.000523
Nuclear Periphery Foci 0.000708 0.001754 0.000698 0.005899 0.000545 0.000816 0.004936 0.001778 0.000626 0.000900 0.001435 0.002316
Nucleolus 0.000426 0.000169 0.000097 0.000050 0.000446 0.000337 0.000173 0.000138 0.000436 0.000322 0.000110 0.000127
Nucleus 0.109150 0.041631 0.170923 0.037839 0.176664 0.056403 0.131015 0.080996 0.143033 0.055083 0.163982 0.075372
Peroxisomes 0.004341 0.006083 0.000658 0.001273 0.002307 0.007602 0.000383 0.001587 0.003320 0.007467 0.000610 0.001546
Vacuole 0.067343 0.140353 0.109929 0.476533 0.056753 0.115100 0.228930 0.226010 0.062028 0.117356 0.130627 0.258661
Vacuole Periphery 0.000463 0.000349 0.000105 0.001509 0.000316 0.001689 0.000119 0.001587 0.000389 0.001569 0.000108 0.001576

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.11 5.74 1.47 1.61 -2.43 -4.72 4.06 2.04 5.58 -2.22 -4.41 6.89 3.64 5.75 -3.16
Bud Neck 3.04 13.10 17.99 3.90 6.11 -3.33 16.81 17.74 15.88 0.47 -3.36 18.78 24.27 16.30 4.78
Bud Site -4.09 -3.22 -1.34 2.87 0.44 -8.85 -0.48 -2.94 3.92 -1.55 -9.86 -3.51 -3.07 4.62 0.26
Cell Periphery 2.62 18.93 15.03 2.63 0.26 6.22 10.35 15.60 10.08 8.53 7.90 20.81 24.58 10.31 7.01
Cytoplasm 5.71 -1.34 18.98 9.04 19.14 8.81 9.85 16.37 7.71 1.44 9.85 2.76 21.02 10.55 16.56
Cytoplasmic Foci -5.43 42.30 29.69 15.46 -3.68 -15.61 6.92 27.42 36.00 11.59 -11.60 43.71 44.68 38.74 1.70
Eisosomes 8.54 17.07 16.65 2.88 -5.49 10.72 19.54 20.34 13.25 8.00 13.60 25.90 25.92 13.52 0.54
Endoplasmic Reticulum 1.13 -2.08 -5.68 -5.85 -4.75 0.14 -3.68 0.57 0.36 6.02 0.02 -2.64 -1.17 -0.80 2.02
Endosome -2.45 16.96 1.49 2.87 -2.18 -12.32 -2.56 4.07 13.37 5.45 -10.95 16.63 7.54 13.35 -2.16
Golgi 4.88 14.87 0.58 -0.66 -1.45 -3.07 16.68 12.89 8.43 -1.79 -1.49 21.42 8.95 6.85 -2.04
Lipid Particles 8.10 15.06 9.16 -0.02 -7.15 -1.74 6.75 12.65 8.81 5.83 1.18 19.04 17.42 8.63 -4.37
Mitochondria 3.06 3.82 -0.15 -0.84 -0.86 -2.24 7.34 0.89 2.42 -1.83 -2.00 6.55 0.78 2.14 -1.65
Mitotic Spindle -1.69 -3.44 -1.87 0.88 -0.69 -2.41 0.15 -6.06 -5.17 -6.09 -2.78 -3.62 -6.27 -4.60 -4.52
None 5.49 3.80 4.60 -2.48 2.32 7.93 6.70 3.60 -5.44 -3.94 7.72 7.34 3.53 -5.43 -4.88
Nuclear Periphery -1.09 -21.70 -9.45 -8.80 -2.75 1.03 -11.93 -17.19 -17.52 -5.75 0.08 -23.74 -19.39 -19.25 -6.16
Nuclear Periphery Foci -3.49 -1.98 -8.33 -5.82 -8.07 -3.51 -9.60 -11.32 -7.09 6.94 -3.68 -9.23 -13.06 -9.31 -4.21
Nucleolus 3.15 4.19 4.77 2.54 3.30 3.21 12.12 9.99 4.68 -0.49 2.53 7.92 6.50 5.14 -2.08
Nucleus 12.73 -16.30 13.24 -0.75 24.80 30.60 5.77 15.34 -12.92 4.15 30.96 -8.27 12.70 -12.39 17.72
Peroxisomes -1.44 7.80 8.85 5.19 0.22 -9.65 14.24 8.50 12.64 -1.98 -7.66 9.25 10.78 13.42 -0.37
Vacuole -7.32 -20.17 -28.43 -21.68 -23.22 -16.56 -20.47 -39.71 -29.81 -6.13 -17.12 -28.11 -45.00 -34.67 -25.73
Vacuole Periphery 1.94 7.34 0.31 -0.13 -0.98 -2.91 5.52 -0.50 2.27 -1.23 -2.74 8.31 -0.22 2.29 -1.40
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphatidylinositol transfer protein (PITP); downregulates Plb1p-mediated turnover of phosphatidylcholine; forms a complex with Psd2p which appears essential for maintenance of vacuolar PE levels; found in the cytosol and microsomes; homologous to Pdr16p; deletion affects phospholipid composition
Localization
Cell Percentages cytoplasm (84%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

Pdr17

Pdr17


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pdr17-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available