Standard name
Human Ortholog
Description L-homoserine-O-acetyltransferase; catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.92 0.99 0.97 0.97 0.98 0.92 0.92 0.92 0.85 0.88 0.7 0.71 0.99 1.0 0.99 – 0.96 0.96 0.88 0.91 0.8 0.91 0.85 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.07 0.08 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0.11 0 0 0.09 0.05 0.16 0.24 0.24 0.35 0.39 0.49 0.47 0 0 0 – 0 0 0.06 0.05 0.05 0 0.05 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – 0 0 0 0 0 0 4 3
Bud 0 3 1 0 1 0 2 5 4 1 1 6 0 1 2 – 0 0 1 0 0 1 9 12
Bud Neck 0 0 0 0 0 1 2 4 1 2 0 1 1 1 0 – 0 0 0 0 0 1 2 3
Bud Site 0 0 0 0 0 0 0 2 1 1 1 1 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 1 0 0 3 3 1 1 0 1 1 – 3 6 0 0 1 1 2 2
Cytoplasm 156 206 73 94 128 124 209 270 161 164 92 138 427 581 634 – 186 140 151 197 59 286 375 352
Endoplasmic Reticulum 0 0 1 3 1 1 0 1 0 1 0 0 2 2 1 – 14 11 0 0 2 0 2 2
Endosome 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 – 2 1 1 0 0 0 2 4
Golgi 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 – 1 1 0 0 0 0 1 4
Mitochondria 19 6 3 9 7 22 54 69 67 73 64 91 1 1 1 – 5 0 10 10 3 10 20 12
Nucleus 0 0 0 1 2 2 1 6 3 0 0 0 0 0 0 – 1 1 0 1 0 0 0 1
Nuclear Periphery 0 1 0 0 1 0 0 1 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – 1 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 0 0 6 3 3 5 0 0 0 – 1 0 2 0 0 3 9 5
Vac/Vac Membrane 2 0 0 0 0 0 0 1 1 0 2 0 0 0 0 – 4 1 3 1 1 2 8 9
Unique Cell Count 170 208 75 97 130 135 228 292 189 187 131 195 431 583 639 193 146 173 216 75 314 444 427
Labelled Cell Count 178 216 78 108 143 151 268 360 247 248 164 244 431 587 641 218 161 173 216 75 314 444 427


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 3.7 3.6 3.9 3.7 3.6 2.5 3.2 3.1 2.5 2.8 2.6 4.2 4.0 4.0 4.9 6.1 6.0 3.9 4.0 4.8
Std Deviation (1e-4) 1.4 0.7 1.2 2.4 1.5 2.4 1.1 1.5 2.1 1.3 1.6 1.7 1.1 1.0 1.1 1.3 2.0 1.7 1.1 1.3 1.6
Intensity Change (Log2) – – – 0.12 0.03 -0.0 -0.53 -0.18 -0.23 -0.52 -0.37 -0.47 0.21 0.14 0.14 0.43 0.77 0.73 0.11 0.16 0.43

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.4298 12.6477 11.7945 11.2809 12.3463 11.9676 6.6654 10.0693 8.296 7.7896 5.7913 8.9864 7.5989 9.9722 9.3031 10.3347 11.683 9.8654
Actin 0.0003 0.001 0.0024 0.0012 0.0007 0.001 0.0447 0.0034 0.0189 0.017 0.0034 0.0038 0.0282 0.0019 0.0225 0.0009 0.003 0.0049
Bud 0.0002 0.0024 0.001 0.0014 0.0006 0.0004 0.001 0.0013 0.0077 0.0021 0.0085 0.0005 0.0011 0.0013 0.0018 0.002 0.0007 0.0005
Bud Neck 0.0003 0.0004 0.0005 0.0007 0.001 0.0017 0.003 0.0003 0.0006 0.001 0.0017 0.0012 0.0024 0.0003 0.0019 0.0005 0.001 0.0016
Bud Periphery 0.0002 0.0012 0.0007 0.0005 0.0002 0.0003 0.0017 0.0005 0.0066 0.0029 0.0068 0.0003 0.0008 0.0005 0.0011 0.0014 0.0004 0.0003
Bud Site 0.0003 0.0105 0.0042 0.0003 0.0002 0.0002 0.0172 0.0027 0.0039 0.0153 0.0014 0.0002 0.0032 0.0024 0.0047 0.0016 0.0006 0.0004
Cell Periphery 0.0001 0.0004 0.0002 0 0 0.0001 0.0007 0.0002 0.0002 0.0004 0.0003 0 0.0003 0.0002 0.0004 0.0002 0.0001 0.0001
Cytoplasm 0.8871 0.9301 0.9134 0.9237 0.934 0.8824 0.6982 0.8803 0.8551 0.7096 0.8192 0.9044 0.757 0.9302 0.8612 0.9384 0.9144 0.929
Cytoplasmic Foci 0.0035 0.0038 0.0056 0.0031 0.0028 0.0046 0.0273 0.0061 0.0185 0.0135 0.0497 0.0117 0.0202 0.0043 0.0132 0.0028 0.0167 0.0105
Eisosomes 0 0 0 0 0 0 0.0006 0 0.0001 0.0001 0 0 0.0002 0 0.0005 0 0 0
Endoplasmic Reticulum 0.0042 0.0032 0.0038 0.0032 0.0049 0.0051 0.0158 0.001 0.0025 0.0036 0.0043 0.002 0.0218 0.0029 0.003 0.0027 0.0054 0.0028
Endosome 0.0017 0.0029 0.0027 0.0025 0.0015 0.0044 0.0306 0.0054 0.005 0.0421 0.0235 0.0081 0.0363 0.0023 0.0087 0.0012 0.0146 0.0044
Golgi 0.0001 0.0003 0.0002 0.0001 0.0001 0.0002 0.0095 0.0032 0.0024 0.0229 0.0027 0.0024 0.0079 0.0003 0.0017 0.0001 0.0009 0.0004
Lipid Particles 0.0001 0.0002 0.0002 0 0 0.0001 0.0192 0.0011 0.0046 0.0158 0.0085 0.0008 0.0085 0.0002 0.0007 0.0001 0.0006 0.0002
Mitochondria 0.0002 0.0006 0.0004 0.0003 0.0004 0.0005 0.0129 0.001 0.0028 0.0224 0.001 0.0007 0.0092 0.0002 0.0015 0.0002 0.0004 0.0003
None 0.0639 0.0115 0.0218 0.0036 0.0173 0.0406 0.0647 0.0735 0.0526 0.0801 0.0181 0.0484 0.0506 0.0425 0.0475 0.0305 0.0179 0.0211
Nuclear Periphery 0.0057 0.0041 0.0043 0.0058 0.0048 0.0059 0.0084 0.0037 0.0014 0.0011 0.0026 0.0014 0.0171 0.0018 0.0041 0.0021 0.0035 0.0026
Nucleolus 0.0001 0.0002 0.0003 0.0001 0 0.0002 0.0009 0 0.0001 0.0002 0.0009 0 0.0004 0.0001 0.0006 0.0001 0.0002 0.0001
Nucleus 0.0288 0.0216 0.032 0.0488 0.0286 0.0481 0.0102 0.0141 0.0054 0.0057 0.0094 0.0071 0.011 0.0054 0.0167 0.0131 0.0133 0.0146
Peroxisomes 0 0.0001 0.0002 0.0001 0.0001 0.0001 0.0196 0.001 0.0079 0.039 0.0179 0.0046 0.0119 0.0001 0.0021 0.0001 0.0004 0.0005
Punctate Nuclear 0.0006 0.0021 0.0028 0.0012 0.0011 0.0019 0.0082 0.0005 0.0022 0.0006 0.005 0.0014 0.0064 0.0012 0.0021 0.0009 0.004 0.0045
Vacuole 0.0024 0.0029 0.0028 0.0027 0.0015 0.0018 0.004 0.0006 0.0011 0.0029 0.0139 0.0007 0.0039 0.0017 0.0031 0.001 0.0015 0.0013
Vacuole Periphery 0.0002 0.0005 0.0003 0.0004 0.0003 0.0003 0.0017 0.0001 0.0002 0.0017 0.0012 0.0002 0.0019 0.0001 0.0008 0.0002 0.0004 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.9091 5.4011 9.5186 21.0679 3.9168 7.5482 8.7035 10.8272 17.4361 6.4244
Translational Efficiency 0.7676 0.9807 1.4849 1.0769 1.1362 0.8272 0.5309 0.9179 0.8168 0.7509

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
821 912 1247 118 265 1803 107 2832 1086 2715 1354 2950

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 598.50 561.91 760.74 819.90 724.95 689.27 910.70 895.40 629.36 646.49 772.59 892.38
Standard Deviation 67.40 109.04 91.00 90.08 129.97 93.39 91.51 110.32 102.50 115.78 99.63 110.58
Intensity Change Log 2 — -0.091012 0.346052 0.454097 — -0.072812 0.329094 0.304651 — -0.081014 0.336788 0.374157

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000044 0.000170 0.000131 0.000193 0.000089 0.000486 0.000156 0.000472 0.000055 0.000380 0.000133 0.000461
Bud Neck 0.004298 0.033374 0.002905 0.001336 0.011462 0.041398 0.000731 0.021278 0.006046 0.038703 0.002734 0.020480
Bud Site 0.001053 0.011662 0.005536 0.002282 0.004946 0.014392 0.000753 0.037171 0.002003 0.013475 0.005158 0.035775
Cell Periphery 0.000140 0.000788 0.000586 0.000320 0.000147 0.000135 0.000252 0.000174 0.000141 0.000354 0.000560 0.000180
Cytoplasm 0.501933 0.405524 0.345707 0.423865 0.541465 0.419710 0.298004 0.603142 0.511580 0.414944 0.341937 0.595971
Cytoplasmic Foci 0.112005 0.190870 0.025320 0.040359 0.246190 0.258316 0.058007 0.003695 0.144748 0.235660 0.027903 0.005162
Eisosomes 0.000118 0.002074 0.000158 0.000120 0.000157 0.000158 0.000158 0.000021 0.000128 0.000802 0.000158 0.000025
Endoplasmic Reticulum 0.000208 0.001801 0.000985 0.002468 0.000673 0.000598 0.003045 0.000509 0.000321 0.001002 0.001147 0.000587
Endosome 0.002543 0.028175 0.002473 0.004676 0.013723 0.023227 0.005384 0.001839 0.005271 0.024889 0.002703 0.001952
Golgi 0.000328 0.003771 0.000104 0.000069 0.002020 0.004504 0.000082 0.000384 0.000741 0.004258 0.000102 0.000371
Lipid Particles 0.005535 0.016017 0.002520 0.002915 0.006303 0.008611 0.004666 0.000379 0.005722 0.011098 0.002690 0.000480
Mitochondria 0.002038 0.007725 0.000775 0.000308 0.003019 0.015198 0.000179 0.003044 0.002278 0.012688 0.000728 0.002934
Mitotic Spindle 0.002394 0.004024 0.003504 0.009791 0.000214 0.004939 0.000036 0.031689 0.001862 0.004632 0.003230 0.030813
None 0.006296 0.061117 0.011539 0.013045 0.006005 0.002265 0.001966 0.006582 0.006225 0.022034 0.010782 0.006841
Nuclear Periphery 0.000628 0.000761 0.001117 0.001166 0.000272 0.000455 0.001245 0.001027 0.000541 0.000558 0.001127 0.001032
Nuclear Periphery Foci 0.000815 0.001232 0.000376 0.001704 0.000600 0.000263 0.002408 0.000087 0.000762 0.000588 0.000536 0.000152
Nucleolus 0.002182 0.006089 0.001336 0.000594 0.000787 0.001749 0.000752 0.000525 0.001841 0.003207 0.001290 0.000528
Nucleus 0.344005 0.140783 0.563354 0.269992 0.093231 0.097923 0.486770 0.247885 0.282812 0.112321 0.557302 0.248769
Peroxisomes 0.001403 0.010395 0.000809 0.000449 0.006990 0.016655 0.000526 0.000334 0.002766 0.014552 0.000787 0.000339
Vacuole 0.011645 0.071445 0.030534 0.224233 0.061038 0.086942 0.134705 0.039214 0.023698 0.081736 0.038766 0.046615
Vacuole Periphery 0.000389 0.002202 0.000231 0.000116 0.000670 0.002076 0.000174 0.000550 0.000458 0.002118 0.000226 0.000532

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.29 -2.79 -5.11 -2.16 -2.55 -2.23 -2.99 -3.30 1.09 -1.46 -2.75 -2.85 -4.11 0.75 -2.20
Bud Neck -9.11 0.90 1.50 10.65 1.33 -9.48 5.10 -1.31 10.55 -14.14 -15.08 2.63 -5.42 11.96 -10.80
Bud Site -5.98 -3.24 -2.29 3.13 0.45 -6.65 4.70 -7.67 -1.83 -11.86 -10.97 -2.50 -10.57 -2.25 -6.72
Cell Periphery -5.62 -5.84 -0.82 4.72 4.11 0.63 -2.91 2.10 1.49 4.56 -5.16 -5.93 2.26 5.83 6.38
Cytoplasm 7.78 14.39 7.16 3.57 1.16 6.36 9.07 3.44 -6.67 -8.45 10.12 16.86 4.45 -7.42 -15.69
Cytoplasmic Foci -9.98 18.20 13.15 20.49 -0.82 -0.80 12.57 17.50 47.18 6.31 -13.65 22.05 27.46 54.26 14.98
Eisosomes -3.85 -2.05 -0.07 3.84 1.97 0.02 0.11 8.58 14.27 8.73 -3.91 -1.66 11.46 4.52 11.24
Endoplasmic Reticulum -3.19 -12.41 -8.40 -3.51 -6.09 0.38 -4.39 -1.55 -4.50 4.10 -3.75 -10.99 -10.87 -0.56 3.61
Endosome -10.97 -0.38 -1.94 10.16 -1.97 -4.16 3.92 6.63 17.64 5.96 -15.20 3.32 6.34 20.77 5.55
Golgi -8.82 1.96 2.27 9.90 1.56 -3.04 2.69 2.55 10.97 -1.36 -10.10 3.24 2.78 13.90 -0.95
Lipid Particles -5.96 3.41 3.50 8.50 -0.04 -1.92 1.52 5.95 11.52 7.09 -5.53 4.11 7.96 14.96 6.41
Mitochondria -3.66 1.29 1.82 6.27 3.03 -4.76 1.47 0.48 7.70 -7.16 -7.01 1.76 0.31 8.79 -4.44
Mitotic Spindle -0.71 -0.64 -1.25 -1.11 -1.15 -5.07 1.56 -11.13 -7.32 -11.24 -2.04 -0.96 -8.66 -7.68 -7.79
None -8.48 -2.32 0.25 7.79 1.44 1.11 1.31 -0.66 -10.90 -17.02 -6.27 -2.04 -1.42 6.24 1.44
Nuclear Periphery -0.85 -4.46 -5.32 -5.23 -3.28 -2.04 -8.10 -11.03 -9.88 -4.46 -0.08 -6.59 -9.25 -9.88 -6.42
Nuclear Periphery Foci -0.75 0.59 -2.00 -2.49 -6.10 3.61 -3.00 4.93 4.33 3.83 0.41 0.29 1.33 5.60 5.46
Nucleolus -3.98 1.38 2.85 8.20 3.39 -3.40 0.71 1.29 5.52 0.98 -2.26 1.21 2.72 9.63 3.01
Nucleus 19.17 -18.35 3.32 -5.10 12.43 -0.67 -12.84 -31.06 -47.23 3.19 21.03 -24.83 -9.49 -45.24 20.11
Peroxisomes -6.89 1.38 3.36 7.94 1.74 -3.62 2.63 2.77 15.45 4.36 -11.21 2.81 4.02 17.35 2.46
Vacuole -15.13 -10.67 -12.96 -10.57 -11.84 -3.10 -5.55 -2.18 1.82 5.04 -19.11 -7.50 -19.39 -2.50 -9.55
Vacuole Periphery -5.32 1.16 2.13 6.68 3.62 -7.22 4.38 3.30 10.83 -1.58 -9.15 2.14 1.79 11.84 -0.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description L-homoserine-O-acetyltransferase; catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway
Localization
Cell Percentages cytoplasm (23%), nucleus (8%), mixed (54%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Met2

Met2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Met2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available