Standard name
Human Ortholog
Description Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.35 0.32 0.52 0.49 0.44 0.4 0.34 0.32 0.23 – 0.31 0.25 0.49 0.51 0.44 0.23 0.16 0.14 0.21 0.14 0.24 0.25 0.24 0.31
Bud 0.05 0.07 0.21 0.1 0.1 0.13 0.07 0.08 0.06 – 0.1 0.1 0 0.07 0.15 0 0.1 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.1 0.24 0.19 0.27 0.26 0.19 0.09 0.1 0.1 – 0.09 0.09 0.31 0.32 0.3 0.27 0.17 0.16 0 0.08 0.07 0.07 0.07 0.18
Cytoplasm 0.13 0.23 0.16 0.19 0.15 0.11 0.11 0.15 0.19 – 0.25 0.18 0.1 0.19 0.29 0.39 0.4 0.5 0 0 0 0 0 0
Endoplasmic Reticulum 0.6 0.46 0.27 0.36 0.43 0.45 0.57 0.51 0.37 – 0.31 0.32 0.46 0.33 0.27 0.06 0 0.08 0.57 0.55 0.49 0.45 0.46 0.41
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.1 0.11 0.09 0 0 0 0 0 0
Mitochondria 0 0 0 0.05 0 0.1 0.1 0.14 0.24 – 0.26 0.28 0 0 0.07 0 0 0 0.05 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0.06 – 0 0.06 0 0 0 0.16 0.17 0.14 0.06 0.11 0.05 0.06 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 73 31 47 109 133 92 107 100 47 – 50 57 86 154 132 31 10 15 52 18 32 42 54 104
Bud 11 7 19 22 31 31 22 25 13 – 17 24 7 20 45 2 6 0 2 2 1 5 8 3
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 4 5 7 10 9 7
Bud Site 0 0 0 2 0 0 1 2 0 – 0 3 0 0 3 0 0 0 – – – – – –
Cell Periphery 22 23 17 59 78 44 29 31 21 – 15 22 54 96 90 36 11 18 7 10 8 11 16 59
Cytoplasm 27 22 15 41 44 26 36 46 39 – 40 42 17 56 87 52 25 56 0 1 0 4 9 1
Endoplasmic Reticulum 126 45 25 80 131 105 181 162 77 – 50 75 81 98 81 8 2 9 139 71 64 75 104 138
Endosome 3 0 0 0 3 0 0 3 4 – 0 1 0 1 4 1 1 2 1 2 1 0 3 4
Golgi 2 0 0 0 4 2 3 5 4 – 2 3 1 1 1 13 7 10 7 0 1 0 2 5
Mitochondria 3 2 1 12 11 23 31 43 49 – 42 66 0 6 20 2 1 4 13 2 5 2 5 2
Nucleus 1 0 0 0 0 0 0 1 3 – 1 0 0 0 1 0 2 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 1 5 1 3 – 0 7 0 2 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 1 2 0 – 0 2 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 1 4 0 0 2 1 – 3 1 0 5 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 0 0 – 0 0 0 2 1 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 2 0 1 0 2 1 4 9 12 – 7 15 1 3 1 21 11 16 14 13 7 10 12 6
Unique Cell Count 211 97 91 221 303 231 317 315 206 162 232 176 301 301 135 63 111 246 130 132 166 229 337
Labelled Cell Count 270 130 125 326 442 325 421 432 273 227 318 247 444 467 167 76 130 246 130 132 166 229 337


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 15.7 13.3 8.6 10.3 10.5 10.1 10.4 9.9 9.9 – 8.9 9.1 15.1 11.6 9.3 21.9 24.7 25.6 13.4 13.3 13.5
Std Deviation (1e-4) 5.4 3.4 2.1 3.5 2.7 2.4 2.6 2.3 2.7 – 2.4 2.4 5.5 4.1 3.3 10.6 12.7 12.7 4.4 4.3 3.6
Intensity Change (Log2) – – – 0.26 0.28 0.22 0.27 0.2 0.2 – 0.04 0.07 0.81 0.43 0.1 1.35 1.52 1.57 0.64 0.63 0.65

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.4 -1.3 -1.9 -3.1 -3.5 -4.9 – -3.3 -4.7 -0.4 -0.1 -1.3 -4.4 -4.5 -5.8
Bud -2.6 -2.7 -1.7 -3.9 -3.5 -3.7 – -2.3 -2.5 -4.4 -4.0 -1.3 -4.9 -1.9 -5.1
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 1.5 1.4 0.1 -2.5 -2.3 -2.0 – -2.2 -2.3 2.1 2.4 2.1 1.4 -0.2 -0.5
Cytoplasm 0.4 -0.5 -1.3 -1.3 -0.4 0.5 – 1.5 0.3 -1.6 0.5 2.4 3.6 3.2 5.0
Endoplasmic Reticulum 1.5 2.7 3.0 5.0 4.0 1.7 – 0.6 0.8 2.9 0.9 -0.1 -4.5 -3.9 -3.7
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 3.0 0 0
Mitochondria 0 0 2.7 2.7 3.4 4.8 – 5.0 5.5 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 3.6 0 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 17.5671 18.4257 15.7472 12.7439 7.934 18.8926 25.3848 21.8324 20.5616 13.5968 14.1279 21.8895 22.4828 13.0858 11.3745 8.5998 10.9571 15.9635
Actin 0.2751 0.3934 0.4259 0.2722 0.1566 0.2492 0.2104 0.1622 0.2935 0.3114 0.3827 0.1939 0.1887 0.3774 0.2433 0.8171 0.2297 0.2876
Bud 0.0049 0.0029 0.0072 0.0036 0.005 0.0027 0.0036 0.0054 0.006 0.0054 0.0055 0.0025 0.0039 0.0042 0.0023 0.0062 0.0014 0.0032
Bud Neck 0.0104 0.015 0.0116 0.0223 0.0172 0.0591 0.0324 0.0153 0.0239 0.0608 0.0675 0.1074 0.0188 0.0202 0.0171 0.0034 0.0257 0.0718
Bud Periphery 0.0142 0.0114 0.0252 0.014 0.0222 0.0167 0.0117 0.0206 0.0265 0.0236 0.0207 0.0218 0.0152 0.0121 0.0064 0.0187 0.0063 0.0167
Bud Site 0.0312 0.0511 0.0231 0.0037 0.0069 0.0029 0.0236 0.0813 0.0454 0.037 0.0092 0.0026 0.0102 0.071 0.0271 0.0081 0.0097 0.0032
Cell Periphery 0.0249 0.1119 0.071 0.0988 0.0669 0.0876 0.1185 0.226 0.1461 0.0572 0.093 0.0785 0.0926 0.0721 0.0543 0.0053 0.1248 0.0886
Cytoplasm 0.0155 0.0228 0.0193 0.0161 0.0168 0.0164 0.0182 0.0577 0.0319 0.0132 0.0499 0.0495 0.0357 0.0206 0.0332 0.0036 0.0293 0.0221
Cytoplasmic Foci 0.0133 0.0115 0.0091 0.006 0.0398 0.0139 0.0248 0.0097 0.0099 0.0543 0.0136 0.0119 0.0074 0.0064 0.0274 0.0274 0.0141 0.0066
Eisosomes 0.0541 0.0788 0.0819 0.0463 0.0105 0.0674 0.0724 0.0704 0.117 0.007 0.0533 0.058 0.0625 0.0655 0.0931 0.0058 0.1267 0.0444
Endoplasmic Reticulum 0.0672 0.0574 0.0772 0.1629 0.0448 0.1745 0.1955 0.1327 0.0945 0.1125 0.0276 0.2042 0.2519 0.1863 0.1412 0.0021 0.1911 0.2668
Endosome 0.0747 0.0213 0.0322 0.0702 0.1506 0.0392 0.043 0.014 0.017 0.0275 0.0251 0.0354 0.0213 0.0263 0.0891 0.0126 0.0824 0.0124
Golgi 0.2627 0.1393 0.1005 0.1301 0.0429 0.1798 0.0931 0.0447 0.093 0.132 0.0934 0.1214 0.1334 0.0547 0.0878 0.0195 0.1059 0.1069
Lipid Particles 0.0484 0.0482 0.0301 0.0272 0.0683 0.0373 0.0504 0.0883 0.0477 0.0726 0.1155 0.0528 0.0577 0.013 0.074 0.0187 0.0293 0.0214
Mitochondria 0.0555 0.002 0.0506 0.0459 0.1861 0.0191 0.0172 0.0013 0.0049 0.0224 0.0132 0.0124 0.0373 0.0007 0.0348 0.0043 0.0048 0.0072
None 0.0046 0.0005 0.0006 0.0015 0.0058 0.0006 0.0047 0.0064 0.0028 0.0024 0.0065 0.0007 0.0046 0.0006 0.0006 0.0067 0.0008 0.0006
Nuclear Periphery 0.0106 0.0034 0.0034 0.022 0.0622 0.0076 0.0313 0.0085 0.0082 0.0164 0.0057 0.0072 0.0241 0.0068 0.004 0.0028 0.0081 0.0041
Nucleolus 0.0015 0.0004 0.0003 0.0004 0.0011 0.0003 0.0014 0.0007 0.0006 0.0007 0.0008 0.0004 0.0008 0.0007 0.0002 0.0002 0.0002 0.0002
Nucleus 0.0034 0.0007 0.0008 0.002 0.0047 0.001 0.004 0.0012 0.0018 0.0025 0.0012 0.0013 0.0083 0.0018 0.0007 0.0004 0.0004 0.0005
Peroxisomes 0.0056 0.0005 0.0011 0.0004 0.0074 0.002 0.0063 0.0006 0.0065 0.0149 0.005 0.0042 0.0009 0.0003 0.0007 0.0234 0.0007 0.0008
Punctate Nuclear 0.0026 0.0003 0.0003 0.0003 0.0032 0.0006 0.0146 0.0007 0.0024 0.0066 0.002 0.0025 0.0101 0.0003 0.0005 0.0127 0.0003 0.0003
Vacuole 0.014 0.024 0.0257 0.0437 0.0617 0.0188 0.0173 0.0498 0.0185 0.0161 0.0065 0.0288 0.0129 0.0559 0.0428 0.0004 0.0064 0.0324
Vacuole Periphery 0.0054 0.0032 0.0029 0.0102 0.0192 0.0034 0.0057 0.0025 0.0019 0.0034 0.0018 0.0028 0.0015 0.0032 0.0193 0.0004 0.0019 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.3539 8.204 42.38 258.8953 101.1405 2.4695 5.7427 11.8432 116.1106 193.346
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
309 316 331 927 1947 608 1468 1691 2256 924 1799 2618

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 896.08 1247.51 2283.39 1594.06 1095.73 1183.44 1708.91 1652.85 1068.38 1205.35 1814.61 1632.03
Standard Deviation 267.80 280.87 510.71 419.85 239.64 256.45 427.20 460.66 253.17 266.79 496.45 447.52
Intensity Change Log 2 — 0.477352 1.349478 0.831006 — 0.111094 0.641184 0.593063 — 0.287440 1.003140 0.704987

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.012329 0.033587 0.004156 0.022022 0.026787 0.032429 0.008388 0.017588 0.024806 0.032825 0.007609 0.019158
Bud Neck 0.032705 0.027311 0.007519 0.012899 0.024302 0.027334 0.004154 0.015716 0.025453 0.027326 0.004773 0.014719
Bud Site 0.234257 0.107881 0.016040 0.079205 0.058616 0.092406 0.020309 0.088583 0.082674 0.097699 0.019523 0.085262
Cell Periphery 0.048080 0.184456 0.195250 0.211718 0.181793 0.194871 0.098744 0.180733 0.163479 0.191309 0.116500 0.191704
Cytoplasm 0.159443 0.063315 0.001650 0.031462 0.127759 0.080407 0.004179 0.045916 0.132099 0.074562 0.003713 0.040798
Cytoplasmic Foci 0.041894 0.025088 0.000461 0.007086 0.016058 0.018267 0.001258 0.012953 0.019597 0.020600 0.001111 0.010876
Eisosomes 0.003006 0.011498 0.004270 0.005194 0.023032 0.016399 0.003477 0.003474 0.020289 0.014723 0.003623 0.004083
Endoplasmic Reticulum 0.340195 0.354461 0.604208 0.404870 0.329614 0.331657 0.779335 0.397907 0.331063 0.339456 0.747113 0.400373
Endosome 0.031524 0.028496 0.010314 0.013137 0.013368 0.021445 0.008480 0.018227 0.015855 0.023856 0.008818 0.016425
Golgi 0.010713 0.017535 0.008775 0.011636 0.008492 0.014823 0.005668 0.012395 0.008796 0.015750 0.006240 0.012126
Lipid Particles 0.019116 0.053313 0.080781 0.145857 0.058693 0.049966 0.047616 0.145539 0.053273 0.051110 0.053718 0.145652
Mitochondria 0.004685 0.004422 0.000286 0.002760 0.011509 0.006029 0.001084 0.002738 0.010574 0.005479 0.000937 0.002746
Mitotic Spindle 0.000671 0.000930 0.000880 0.001803 0.000313 0.000715 0.000477 0.002909 0.000362 0.000789 0.000551 0.002518
None 0.001909 0.000246 0.000093 0.000393 0.003327 0.000157 0.000491 0.000845 0.003133 0.000188 0.000417 0.000685
Nuclear Periphery 0.000256 0.000880 0.005579 0.002555 0.000569 0.000509 0.002799 0.003035 0.000526 0.000636 0.003311 0.002865
Nuclear Periphery Foci 0.002914 0.003266 0.005979 0.004191 0.001061 0.001058 0.001186 0.003831 0.001315 0.001813 0.002068 0.003959
Nucleolus 0.000162 0.000070 0.000016 0.000038 0.000168 0.000158 0.000018 0.000062 0.000168 0.000128 0.000017 0.000053
Nucleus 0.006390 0.001943 0.000456 0.001779 0.003935 0.002501 0.000372 0.002353 0.004271 0.002310 0.000388 0.002150
Peroxisomes 0.005112 0.016520 0.000237 0.004494 0.089001 0.037841 0.003545 0.006793 0.077511 0.030549 0.002936 0.005979
Vacuole 0.039981 0.061751 0.051303 0.035015 0.020048 0.065871 0.007461 0.035184 0.022778 0.064462 0.015527 0.035124
Vacuole Periphery 0.004657 0.003030 0.001745 0.001883 0.001552 0.005159 0.000962 0.003219 0.001978 0.004431 0.001106 0.002746

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.86 3.20 -3.03 1.98 -6.87 -1.42 8.31 3.66 3.80 -5.14 -2.41 8.94 2.48 4.21 -7.45
Bud Neck 0.96 5.65 4.42 3.41 -3.52 -0.83 13.21 4.48 3.28 -8.93 -0.61 14.24 6.46 4.60 -10.24
Bud Site 6.25 12.50 8.61 2.08 -9.11 -4.61 10.44 -6.05 0.12 -13.78 -2.20 15.19 -1.08 1.40 -16.58
Cell Periphery -9.69 -10.94 -15.89 -1.69 -0.91 -1.19 13.24 0.48 1.47 -11.71 -3.09 7.92 -4.04 0.16 -11.81
Cytoplasm 5.84 12.00 9.36 3.81 -10.78 6.49 29.27 15.77 5.09 -14.73 8.82 31.58 19.60 6.39 -17.72
Cytoplasmic Foci 2.52 7.88 6.44 4.01 -6.97 -0.99 12.58 1.63 2.14 -10.24 -0.43 14.70 5.56 4.36 -11.97
Eisosomes -5.33 -1.24 -2.82 4.05 -0.89 3.42 15.90 16.26 8.16 0.07 3.66 15.43 15.37 9.07 -1.04
Endoplasmic Reticulum -0.38 -9.20 -2.43 -2.12 9.30 -0.08 -44.38 -5.64 -3.98 35.37 -0.52 -42.50 -6.58 -4.46 36.57
Endosome 0.67 5.67 4.99 4.28 -1.96 -4.27 6.61 -4.08 1.43 -8.73 -4.38 8.43 -0.73 3.93 -9.12
Golgi -2.04 1.11 -0.37 1.82 -1.65 -2.85 3.55 -3.41 1.04 -6.12 -3.83 3.56 -3.29 1.91 -6.26
Lipid Particles -5.01 -7.25 -15.97 -9.80 -5.91 1.81 2.73 -14.80 -13.97 -15.68 0.59 -0.16 -19.15 -17.08 -17.38
Mitochondria 0.19 5.33 1.60 1.05 -2.81 3.79 13.48 9.98 2.55 -3.60 4.49 14.21 9.91 2.72 -4.16
Mitotic Spindle -0.45 -0.65 -3.03 -1.52 -2.20 -1.52 -4.12 -4.51 -3.58 -4.25 -1.67 -2.90 -5.47 -3.89 -5.00
None 2.90 3.21 2.64 -1.05 -2.78 5.53 4.84 3.96 -2.64 -1.23 5.88 5.32 4.64 -2.84 -1.33
Nuclear Periphery -1.28 -12.78 -11.76 -3.17 6.71 1.17 -13.43 -14.31 -14.28 -0.83 -0.64 -17.65 -17.79 -10.41 2.41
Nuclear Periphery Foci -0.17 -2.07 -2.71 -0.63 1.02 -0.00 -0.76 -9.77 -10.65 -10.07 -0.72 -2.46 -10.63 -3.30 -5.60
Nucleolus 3.26 6.13 5.07 2.09 -4.40 0.01 13.92 8.68 1.02 -7.33 0.48 15.18 10.65 1.19 -8.37
Nucleus 2.69 4.64 3.38 0.37 -5.56 1.42 14.69 3.78 0.30 -9.48 2.61 14.20 5.66 0.46 -11.15
Peroxisomes -3.84 6.00 0.74 4.18 -8.91 9.42 23.48 22.46 7.46 -3.28 11.02 23.33 22.39 8.39 -4.16
Vacuole -2.30 -1.81 0.20 2.70 2.77 -6.54 7.77 -7.30 4.13 -16.21 -7.54 3.99 -7.05 4.93 -12.59
Vacuole Periphery 2.13 4.40 4.27 2.28 -0.43 -2.93 2.85 -2.67 1.44 -3.61 -2.94 4.38 -1.78 1.86 -3.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
Localization
Cell Percentages ER (56%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Egt2

Egt2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Egt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available