Standard name
Human Ortholog
Description Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.16 0.1 0 0.15 0.21 0.34 0.5 0.4 0.52 0.64 0.71 0.66 0.05 0 0.05 0 0 0 0.05 0 0.1 0.07 0.07 0.08
Nucleus 0.74 0.74 0.78 0.8 0.69 0.68 0.59 0.59 0.57 0.52 0.47 0.45 0.7 0.68 0.68 0.83 0.83 0.87 0.57 0.62 0.38 0.38 0.27 0.19
Nuclear Periphery 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.2 0.22 0.19 0.08 0.16 0.13 0.1 0.14 0.13 0.1 0.11 0.16 0.24 0.27 0.22 0.07 0.1 0.08 0.35 0.34 0.48 0.48 0.58 0.62
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 0 0 0 0 0 0 0 0 1
Bud 0 0 0 0 2 2 7 8 0 1 8 5 0 0 1 0 0 0 0 0 1 1 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 1 6 9 4 2 9 4 11 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 4 3 1 0 0 0 0 0 0 0 0
Cytoplasm 1 1 5 15 9 4 20 11 7 9 12 11 12 23 23 26 18 11 0 0 0 3 6 5
Endoplasmic Reticulum 0 0 0 1 0 0 0 1 0 1 0 0 0 0 2 7 9 3 0 0 0 2 2 5
Endosome 0 0 0 0 2 0 0 0 0 0 0 1 4 10 16 2 1 1 1 0 3 5 7 10
Golgi 0 0 0 0 1 0 0 0 0 0 0 0 2 1 6 0 1 0 2 0 2 3 12 18
Mitochondria 32 13 10 50 73 172 375 282 252 385 412 455 19 15 28 5 8 4 11 1 29 25 31 43
Nucleus 144 93 197 272 242 344 442 414 276 313 276 309 242 363 381 258 234 209 120 81 110 136 127 104
Nuclear Periphery 2 0 2 1 5 13 23 35 14 15 18 19 1 1 2 4 0 0 0 0 1 2 3 4
Nucleolus 2 2 1 1 1 10 19 18 8 10 19 11 1 0 1 3 0 4 0 0 1 0 1 0
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 1 4 7 0 1 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 2 1 0 0 1 1 4 4 0 1 0 0 1 0 3 1 0
Vac/Vac Membrane 38 28 48 29 56 65 73 99 61 63 66 110 82 145 123 21 27 20 73 43 140 172 279 333
Unique Cell Count 194 125 251 342 349 504 747 706 484 604 584 693 348 537 564 311 282 240 213 131 293 358 478 536
Labelled Cell Count 219 137 263 369 392 616 968 875 621 806 815 934 366 572 600 327 300 252 213 131 293 358 478 536


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.3 8.8 8.4 7.8 7.1 5.9 5.3 5.5 5.0 4.7 4.5 4.6 9.9 9.3 9.0 12.1 12.1 11.2 10.9 11.2 11.5
Std Deviation (1e-4) 1.5 2.1 1.7 1.9 1.8 1.4 1.3 1.3 1.2 1.1 1.3 1.1 6.4 1.8 2.0 3.4 3.6 3.2 2.2 2.3 2.3
Intensity Change (Log2) – – – -0.12 -0.25 -0.51 -0.68 -0.62 -0.76 -0.83 -0.91 -0.88 0.23 0.14 0.09 0.52 0.52 0.41 0.36 0.41 0.45

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.6 0.5 0 0.6 0 0 0 0.1 0 1.1 1.6 1.5 3.3 2.5 1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.2 5.9 9.1 13.0 10.6 12.9 0 0 0 0.8 -0.9 0.6 -1.7 -0.7 -1.5
Nucleus 0.3 -2.5 -2.9 -5.5 -5.6 -5.8 -7.2 -8.3 -9.2 -2.4 -3.1 -3.2 1.3 1.3 2.5
Nuclear Periphery 0 0 0 2.0 2.9 1.8 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 2.1 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -3.8 -1.0 -2.3 -3.9 -1.9 -2.4 -3.4 -3.0 -1.2 1.3 2.4 0.9 -4.4 -3.2 -3.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.1019 6.5086 5.9579 5.9946 4.905 5.9779 3.6082 4.7401 4.1081 3.8326 3.1493 3.8243 2.4595 3.3271 2.67 2.0956 1.6465 2.5604
Actin 0.0105 0.0004 0.0146 0.0068 0.0023 0.0008 0.0112 0.0004 0.0064 0.0144 0.0148 0.0025 0.0081 0 0.0156 0.0108 0.0022 0
Bud 0.0005 0.0002 0.0001 0.0006 0.0002 0.0002 0.0007 0.0001 0.0004 0.0003 0.0008 0.0003 0.0004 0.0001 0.0002 0.0004 0.0003 0.0001
Bud Neck 0.0018 0.0002 0.0004 0.0027 0.001 0.0023 0.0017 0.0001 0.0007 0.0003 0.0006 0.003 0.0004 0.0001 0.0003 0.0002 0.0004 0.0007
Bud Periphery 0.0012 0.0005 0.0002 0.0022 0.0004 0.0009 0.0019 0.0001 0.0008 0.0005 0.0029 0.0012 0.0009 0.0002 0.0003 0.0008 0.001 0.0003
Bud Site 0.0013 0.0005 0.0005 0.0008 0.0003 0.0001 0.0037 0.0001 0.0007 0.0007 0.0007 0.0005 0.001 0.0001 0.0007 0.0011 0.0004 0.0001
Cell Periphery 0.0004 0.0001 0.0001 0.0006 0.0002 0.0002 0.0009 0 0.0002 0.0002 0.0007 0.0003 0.0002 0.0001 0.0001 0.0001 0.0002 0.0001
Cytoplasm 0.0022 0.0011 0.0004 0.0015 0.0105 0.0012 0.0044 0.0016 0.0019 0.0097 0.0005 0.0009 0.0075 0.0008 0.001 0.0009 0.0009 0.0014
Cytoplasmic Foci 0.0021 0.0015 0.0004 0.001 0.004 0.0009 0.0146 0 0.0059 0.0086 0.0007 0.001 0.01 0 0.0066 0.0117 0.0003 0.0001
Eisosomes 0.0002 0 0.0002 0.0003 0 0 0.0002 0 0.0001 0.0001 0.0003 0.0001 0.0001 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.005 0.0005 0.0009 0.0024 0.0067 0.0005 0.0036 0.0004 0.001 0.0032 0.0008 0.002 0.0033 0.0002 0.0004 0.0016 0.0024 0.0002
Endosome 0.0128 0.0028 0.0015 0.0073 0.0046 0.001 0.0199 0.0003 0.013 0.0221 0.0047 0.0058 0.0333 0.0001 0.0061 0.0317 0.008 0.0021
Golgi 0.0035 0.0004 0.0011 0.0023 0.0013 0.0002 0.0045 0 0.0053 0.0092 0.0072 0.0027 0.0034 0 0.003 0.0173 0.0008 0
Lipid Particles 0.0054 0.0043 0.001 0.011 0.0135 0.0002 0.0091 0 0.0051 0.0104 0.0034 0.0108 0.0098 0 0.0084 0.0054 0.0007 0
Mitochondria 0.0205 0.0084 0.0107 0.0508 0.0213 0.0038 0.021 0.0072 0.0236 0.0364 0.0802 0.0119 0.0189 0.0016 0.0072 0.0538 0.0459 0.0012
None 0.0014 0.0002 0.0003 0.0018 0.0007 0.0002 0.0052 0.0001 0.0005 0.0077 0.0005 0.0003 0.0012 0 0.0005 0.0003 0.0006 0
Nuclear Periphery 0.0275 0.0215 0.0247 0.0233 0.0312 0.0151 0.0353 0.0155 0.0197 0.0066 0.0107 0.0173 0.0167 0.0135 0.0128 0.0152 0.0517 0.0022
Nucleolus 0.0119 0.0069 0.0054 0.0162 0.023 0.0195 0.008 0.0055 0.007 0.004 0.0164 0.0119 0.0073 0.0049 0.0083 0.0073 0.0267 0.0139
Nucleus 0.8723 0.9435 0.934 0.8522 0.867 0.9465 0.8222 0.9666 0.894 0.8566 0.8426 0.9155 0.8553 0.9758 0.9111 0.807 0.8467 0.9691
Peroxisomes 0.003 0.0002 0.0007 0.001 0.0018 0.0001 0.011 0 0.0015 0.0024 0.0012 0.001 0.0008 0 0.0088 0.0237 0.0002 0
Punctate Nuclear 0.0057 0.0016 0.0005 0.0055 0.0053 0.0027 0.0057 0.0002 0.0025 0.0026 0.0004 0.0027 0.0107 0.0001 0.002 0.0014 0.0022 0.0002
Vacuole 0.0054 0.0016 0.0009 0.0038 0.0022 0.0016 0.008 0.0007 0.0043 0.0014 0.0034 0.0045 0.0062 0.0012 0.0034 0.0024 0.0027 0.0044
Vacuole Periphery 0.0052 0.0035 0.0014 0.0059 0.0025 0.0021 0.0073 0.0011 0.0056 0.0024 0.0066 0.0037 0.0042 0.0011 0.0033 0.007 0.0057 0.0036

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 48.7218 52.0943 40.5574 32.0996 27.2498 30.5536 33.2441 35.259 29.2045 31.2867
Translational Efficiency 0.8526 0.7466 0.8644 0.9014 1.1285 0.9632 0.8278 0.8444 0.8942 0.8499

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1564 109 262 649 1756 1690 1258 1283 3320 1799 1520 1932

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 944.00 1144.60 1222.73 1188.11 906.79 1001.16 1117.33 1152.77 924.32 1009.85 1135.50 1164.64
Standard Deviation 136.15 204.49 174.48 184.37 143.30 163.82 163.82 204.04 141.20 170.05 170.42 198.35
Intensity Change Log 2 — 0.277985 0.373247 0.331810 — 0.142832 0.301215 0.346264 — 0.213348 0.338404 0.338910

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003706 0.006811 0.000964 0.021662 0.003368 0.003770 0.000892 0.023047 0.003528 0.003955 0.000904 0.022582
Bud Neck 0.027942 0.048137 0.011944 0.130790 0.035962 0.047124 0.011741 0.141940 0.032184 0.047186 0.011776 0.138194
Bud Site 0.007965 0.013482 0.001070 0.049648 0.010528 0.010364 0.001326 0.079053 0.009321 0.010553 0.001282 0.069175
Cell Periphery 0.000652 0.000299 0.000059 0.000595 0.000780 0.000885 0.000196 0.001016 0.000720 0.000850 0.000172 0.000875
Cytoplasm 0.000813 0.009671 0.000230 0.005057 0.002167 0.001241 0.001353 0.008137 0.001530 0.001752 0.001160 0.007102
Cytoplasmic Foci 0.000999 0.001225 0.000034 0.002057 0.000959 0.002732 0.000059 0.003934 0.000978 0.002641 0.000055 0.003303
Eisosomes 0.000121 0.000230 0.000056 0.000185 0.000104 0.000145 0.000047 0.000215 0.000112 0.000151 0.000048 0.000205
Endoplasmic Reticulum 0.065452 0.040384 0.005749 0.050984 0.063435 0.056654 0.008953 0.058706 0.064385 0.055668 0.008400 0.056112
Endosome 0.001344 0.001085 0.000107 0.004253 0.002024 0.003852 0.000219 0.006045 0.001704 0.003685 0.000200 0.005443
Golgi 0.000694 0.000547 0.000041 0.001756 0.000668 0.001411 0.000048 0.005178 0.000681 0.001359 0.000047 0.004029
Lipid Particles 0.001832 0.001516 0.000100 0.002619 0.001896 0.002369 0.000095 0.002720 0.001866 0.002317 0.000096 0.002686
Mitochondria 0.035969 0.020089 0.001468 0.080997 0.032283 0.047542 0.001351 0.099255 0.034020 0.045879 0.001371 0.093122
Mitotic Spindle 0.001909 0.019308 0.001545 0.060697 0.005903 0.004027 0.000590 0.055250 0.004022 0.004953 0.000754 0.057080
None 0.002742 0.001870 0.000436 0.001865 0.003400 0.002766 0.002214 0.003097 0.003090 0.002712 0.001908 0.002683
Nuclear Periphery 0.002822 0.000603 0.000223 0.007829 0.004955 0.005211 0.000476 0.005984 0.003950 0.004931 0.000432 0.006604
Nuclear Periphery Foci 0.001789 0.001606 0.000059 0.005729 0.002187 0.001696 0.000251 0.003817 0.001999 0.001690 0.000217 0.004459
Nucleolus 0.021334 0.032218 0.003185 0.016291 0.020817 0.027261 0.004483 0.008555 0.021061 0.027562 0.004260 0.011154
Nucleus 0.801796 0.768846 0.970642 0.506812 0.787645 0.747622 0.963916 0.429089 0.794311 0.748908 0.965075 0.455198
Peroxisomes 0.008004 0.013037 0.000410 0.007603 0.006821 0.005920 0.000243 0.011340 0.007378 0.006351 0.000272 0.010085
Vacuole 0.009482 0.010425 0.001579 0.035804 0.011139 0.020586 0.001448 0.046652 0.010358 0.019971 0.001470 0.043008
Vacuole Periphery 0.002631 0.008614 0.000099 0.006767 0.002958 0.006819 0.000099 0.006968 0.002804 0.006927 0.000099 0.006901

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.55 11.10 -8.20 -5.84 -9.43 -1.10 9.46 -13.34 -13.12 -15.14 -1.48 14.40 -15.58 -15.11 -17.76
Bud Neck -2.13 7.39 -17.38 -7.81 -20.18 -3.88 11.21 -21.73 -19.07 -27.71 -6.03 13.12 -28.12 -22.39 -34.17
Bud Site -1.82 9.16 -12.77 -8.31 -15.05 0.17 11.96 -21.74 -21.84 -25.26 -1.46 14.51 -25.24 -24.29 -29.14
Cell Periphery 4.42 9.02 0.60 -5.14 -13.95 -0.43 9.08 -2.67 -0.42 -13.56 -0.57 11.08 -2.44 -0.04 -15.78
Cytoplasm -0.99 2.04 -4.75 0.48 -5.65 1.40 1.39 -6.46 -7.11 -7.40 -0.31 0.80 -8.21 -5.99 -8.57
Cytoplasmic Foci -0.37 3.79 -2.53 -1.54 -6.74 -2.53 5.96 -4.57 -0.82 -6.58 -2.51 6.36 -5.08 -0.44 -8.20
Eisosomes -2.85 10.75 -5.58 1.12 -11.27 -6.61 12.60 -12.21 -7.16 -20.14 -6.48 17.77 -12.94 -6.43 -23.19
Endoplasmic Reticulum 4.66 24.01 3.88 -2.00 -15.31 2.44 25.06 1.38 -0.84 -21.08 3.79 35.19 3.29 -0.39 -25.93
Endosome 0.62 11.22 -4.86 -4.47 -7.19 -3.03 9.07 -5.92 -2.03 -9.80 -3.66 12.72 -7.81 -1.95 -11.97
Golgi 0.37 2.01 -1.73 -2.40 -4.15 -1.83 4.68 -3.97 -2.97 -4.76 -1.73 3.80 -4.24 -2.87 -5.51
Lipid Particles 0.56 6.47 -2.89 -2.61 -9.51 -0.71 5.94 -2.49 -0.91 -12.03 -0.78 8.74 -3.76 -1.16 -15.34
Mitochondria 3.03 12.10 -5.64 -7.22 -12.57 -3.85 12.52 -10.87 -7.39 -19.38 -3.41 17.41 -12.11 -7.94 -23.08
Mitotic Spindle -1.81 -0.37 -8.43 -3.12 -7.54 1.35 4.09 -10.03 -10.66 -11.52 -0.78 3.19 -13.31 -12.84 -14.13
None 0.78 3.14 1.28 0.24 -5.22 0.84 1.57 0.73 -0.02 -0.81 0.61 1.98 1.07 0.50 -1.02
Nuclear Periphery 8.40 10.36 -4.86 -7.38 -7.80 -0.35 9.10 -1.34 -1.00 -7.70 -1.68 12.22 -4.11 -2.13 -10.61
Nuclear Periphery Foci 0.12 3.95 -3.99 -3.24 -6.21 1.11 4.23 -2.74 -4.51 -7.93 0.90 5.40 -4.87 -5.98 -9.78
Nucleolus -1.38 14.67 2.81 2.02 -9.10 -3.42 11.86 8.67 12.11 -3.94 -3.98 17.25 9.29 10.79 -8.09
Nucleus 1.35 -22.39 20.60 9.09 33.56 4.41 -27.97 31.38 26.88 54.47 5.85 -36.87 38.06 28.80 63.78
Peroxisomes -1.51 7.92 0.55 1.73 -8.04 0.88 7.26 -2.01 -2.94 -8.18 1.17 10.79 -1.50 -2.53 -10.49
Vacuole -0.34 10.10 -9.90 -7.38 -12.79 -5.67 11.28 -16.22 -10.93 -21.64 -6.55 15.66 -19.27 -11.57 -25.11
Vacuole Periphery -0.84 6.45 -2.80 0.40 -5.55 -4.56 7.31 -3.24 0.79 -7.04 -4.77 9.74 -4.31 1.04 -8.90
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs
Localization
Cell Percentages nucleus (46%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Smm1

Smm1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Smm1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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