Standard name
Human Ortholog
Description Para-aminobenzoate (PABA) synthase; has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.98 0.95 0.96 0.9 0.89 – 0.81 0.77 0.71 0.78 0.99 0.99 0.99 0.92 0.96 0.96 0.98 0.96 0.96 0.92 0.9 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.1 0.12 – 0.24 0.23 0.3 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0 0.08 0 – 0.05 0.12 0.09 0.09 0 0 0 0.07 0.07 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 1 0 0 0 1 0 1 1 1
Bud 0 0 1 0 0 0 2 – 4 10 7 5 1 0 0 0 0 0 0 0 0 1 5 3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 2 8 5 6 10 5 – 9 7 13 7 0 2 2 18 11 15 0 0 0 0 0 0
Cytoplasm 267 587 445 330 366 442 499 – 451 387 355 337 333 429 471 532 354 361 259 584 442 268 329 368
Endoplasmic Reticulum 0 1 0 1 0 0 1 – 1 0 5 0 2 1 2 16 10 8 0 0 2 3 4 3
Endosome 0 0 0 0 0 1 0 – 0 1 1 4 0 0 0 3 0 0 1 3 1 2 2 1
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 3
Mitochondria 1 2 3 7 9 49 66 – 132 113 151 78 0 0 3 3 1 3 0 3 1 1 3 1
Nucleus 1 1 0 1 0 2 4 – 2 7 3 8 1 2 3 16 3 13 0 3 0 1 0 0
Nuclear Periphery 0 0 0 1 0 0 1 – 0 2 5 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 1 0 – 1 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 1 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 1 0 2 0 0
Vac/Vac Membrane 0 1 11 17 14 37 18 – 27 60 47 39 1 1 1 40 25 16 0 6 6 3 12 11
Unique Cell Count 269 593 455 347 380 493 562 559 500 497 431 337 434 477 576 368 377 264 611 462 290 366 402
Labelled Cell Count 272 595 468 362 396 542 596 627 589 588 479 338 436 482 631 404 416 264 611 462 290 366 402


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.1 7.3 7.3 7.0 7.2 6.0 6.0 – 5.5 5.4 5.5 5.8 6.7 6.9 6.7 9.4 10.3 9.3 6.5 6.4 6.9
Std Deviation (1e-4) 0.9 1.0 0.9 1.4 1.2 1.2 1.0 – 1.0 1.0 1.0 1.1 0.9 1.0 0.9 1.7 1.9 2.2 1.3 1.0 1.3
Intensity Change (Log2) – – – -0.05 -0.0 -0.26 -0.26 – -0.4 -0.43 -0.41 -0.32 -0.11 -0.08 -0.11 0.38 0.5 0.36 -0.17 -0.19 -0.07

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 2.6 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.4 -0.2 0.3 -1.2 – -0.2 -0.4 0.9 -0.2 0 0 0 1.4 1.2 1.9
Cytoplasm -2.1 -1.3 -5.1 -5.5 – -8.5 -9.4 -11.1 -9.1 1.1 1.2 1.1 -3.9 -1.4 -1.7
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 3.6 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.1 6.3 7.0 – 10.7 10.4 12.4 9.0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 3.6 0 4.0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 1.9 1.1 3.6 0.7 – 2.0 5.6 4.5 4.3 -2.4 -2.8 -3.0 3.3 3.1 1.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3492 1.4491 1.1635 1.0573 1.4351 1.5971 3.8048 3.7989 3.773 3.6053 3.4895 3.6957 2.4237 2.9285 2.9214 2.9396 2.7538 2.8657
Actin 0.0155 0.0006 0.0322 0.0005 0.0005 0.0092 0.0346 0.0018 0.008 0.0016 0.0517 0.02 0.0004 0.0014 0.0011 0.0009 0.0227 0.0007
Bud 0.0015 0.0009 0.0012 0.0004 0.0039 0.0049 0.0028 0.0016 0.0031 0.0004 0.0014 0.0018 0.0032 0.0109 0.0078 0.0045 0.0012 0.0032
Bud Neck 0.0054 0.0002 0.0033 0.0008 0.0025 0.0073 0.0237 0.001 0.0019 0.0009 0.0008 0.0029 0.0003 0.0006 0.0007 0.0003 0.0006 0.0023
Bud Periphery 0.0018 0.0002 0.0013 0.0002 0.0018 0.0027 0.0059 0.0008 0.0025 0.0002 0.0006 0.0035 0.0018 0.0025 0.0036 0.0018 0.0042 0.0008
Bud Site 0.0124 0.0025 0.0095 0.0008 0.0114 0.0007 0.0261 0.0221 0.0068 0.0009 0.0008 0.0014 0.0016 0.0127 0.0041 0.0003 0.0032 0.0003
Cell Periphery 0.0005 0.0001 0.0003 0 0.0002 0.0003 0.0009 0.0003 0.0004 0 0.0001 0.0002 0.0001 0.0002 0.0002 0 0.0004 0.0001
Cytoplasm 0.4881 0.7327 0.6711 0.7388 0.6022 0.692 0.5613 0.8452 0.8541 0.8459 0.5477 0.8105 0.7493 0.8714 0.7859 0.7672 0.7899 0.8166
Cytoplasmic Foci 0.0291 0.0085 0.0209 0.0152 0.0208 0.0223 0.0383 0.0095 0.0142 0.039 0.0525 0.0145 0.0146 0.0125 0.0096 0.0321 0.0227 0.0152
Eisosomes 0.0003 0 0.0006 0 0 0.0001 0.0003 0 0 0 0.0001 0.0001 0 0 0 0 0.0003 0
Endoplasmic Reticulum 0.0075 0.0031 0.0028 0.0055 0.0097 0.0062 0.0086 0.0026 0.0029 0.0026 0.0027 0.0029 0.0025 0.0018 0.0021 0.0021 0.0033 0.0023
Endosome 0.0599 0.0045 0.0079 0.0137 0.0245 0.0217 0.0523 0.0032 0.0129 0.0215 0.0662 0.0117 0.004 0.0054 0.0025 0.0044 0.0118 0.0059
Golgi 0.0127 0.0003 0.0019 0.0004 0.0008 0.0058 0.0128 0.0005 0.0042 0.004 0.0185 0.0082 0.0004 0.0005 0.0005 0.0003 0.0052 0.0002
Lipid Particles 0.009 0.0002 0.0079 0.0003 0.0003 0.0043 0.0223 0.0003 0.0068 0.0035 0.0292 0.0119 0.0005 0.0001 0.0001 0.0001 0.0124 0.0001
Mitochondria 0.0082 0.0003 0.0109 0.0003 0.002 0.0069 0.0053 0.0004 0.0028 0.0007 0.0035 0.0113 0.0005 0.0004 0.0006 0.0007 0.007 0.0004
None 0.232 0.2318 0.1944 0.2084 0.2877 0.1904 0.1076 0.0921 0.0552 0.0449 0.2018 0.0673 0.1992 0.0666 0.1602 0.1574 0.0483 0.1283
Nuclear Periphery 0.0396 0.0015 0.0023 0.0027 0.0052 0.0052 0.0272 0.002 0.0019 0.0017 0.002 0.0042 0.0013 0.0012 0.0013 0.002 0.0022 0.0018
Nucleolus 0.0049 0.0004 0.0021 0.0002 0.0006 0.0004 0.0038 0.0005 0.0007 0.0002 0.0003 0.001 0.0004 0.0002 0.0003 0.0002 0.0011 0.0003
Nucleus 0.0275 0.0067 0.006 0.0049 0.0146 0.0072 0.0208 0.011 0.0057 0.0065 0.0019 0.0106 0.0083 0.0066 0.0066 0.0078 0.006 0.0116
Peroxisomes 0.0044 0.0002 0.0083 0.0002 0.0004 0.0029 0.0172 0.0005 0.0035 0.0131 0.0126 0.0077 0.0006 0.0004 0.0076 0.0109 0.045 0.0002
Punctate Nuclear 0.0201 0.0034 0.0131 0.0039 0.0024 0.0054 0.0179 0.0027 0.0026 0.0113 0.0027 0.0056 0.0098 0.003 0.0037 0.0056 0.0067 0.0084
Vacuole 0.0142 0.0017 0.0018 0.0021 0.007 0.0035 0.0076 0.0017 0.0087 0.0008 0.0024 0.0021 0.0009 0.0014 0.0011 0.0012 0.0049 0.001
Vacuole Periphery 0.0053 0.0002 0.0004 0.0005 0.0014 0.0009 0.0027 0.0003 0.0011 0.0002 0.0007 0.0007 0.0001 0.0002 0.0002 0.0003 0.0008 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 28.2386 19.1934 15.1712 22.728 22.3911 21.9253 30.5863 27.7622 28.2401 26.2294
Translational Efficiency 0.9409 0.8576 0.8139 0.6841 0.6796 1.1616 0.7663 0.6544 0.6927 0.7536

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2136 1001 1410 1217 1485 1778 1070 375 3621 2779 2480 1592

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 753.43 913.68 1062.08 1085.29 811.96 904.00 1015.65 1381.15 777.43 907.49 1042.05 1154.98
Standard Deviation 87.60 133.27 131.48 167.06 97.99 118.16 133.16 216.70 96.40 123.91 134.19 219.45
Intensity Change Log 2 — 0.278215 0.495347 0.526535 — 0.154914 0.322923 0.766389 — 0.215576 0.408486 0.655908

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000063 0.000169 0.000333 0.007763 0.000208 0.000894 0.000221 0.000063 0.000123 0.000633 0.000285 0.005949
Bud Neck 0.004531 0.003355 0.003760 0.011388 0.003108 0.006456 0.003467 0.003387 0.003947 0.005339 0.003633 0.009504
Bud Site 0.004539 0.008620 0.007661 0.043877 0.005120 0.014239 0.006374 0.011387 0.004777 0.012215 0.007106 0.036224
Cell Periphery 0.000090 0.000071 0.000108 0.000195 0.000099 0.000065 0.000099 0.000029 0.000094 0.000067 0.000104 0.000156
Cytoplasm 0.701301 0.711000 0.444199 0.512937 0.690414 0.708167 0.631488 0.806404 0.696836 0.709187 0.525005 0.582064
Cytoplasmic Foci 0.089910 0.091851 0.004694 0.017766 0.123564 0.104920 0.011130 0.001782 0.103712 0.100212 0.007471 0.014001
Eisosomes 0.000046 0.000029 0.000019 0.000030 0.000045 0.000034 0.000026 0.000002 0.000046 0.000032 0.000022 0.000024
Endoplasmic Reticulum 0.000501 0.001031 0.002967 0.002141 0.001608 0.000642 0.001868 0.000046 0.000955 0.000782 0.002493 0.001647
Endosome 0.003272 0.010683 0.001467 0.010879 0.005098 0.008696 0.002152 0.000208 0.004021 0.009412 0.001762 0.008366
Golgi 0.000790 0.001639 0.000076 0.009096 0.000819 0.004296 0.000086 0.001127 0.000802 0.003339 0.000080 0.007219
Lipid Particles 0.001565 0.001461 0.000791 0.004579 0.001813 0.001006 0.000906 0.000055 0.001667 0.001170 0.000841 0.003513
Mitochondria 0.001532 0.001458 0.001019 0.010799 0.001051 0.003108 0.000283 0.001109 0.001334 0.002514 0.000701 0.008516
Mitotic Spindle 0.002580 0.007749 0.008386 0.099856 0.001516 0.012073 0.006222 0.010956 0.002144 0.010515 0.007452 0.078915
None 0.007957 0.003574 0.006008 0.010801 0.002292 0.001695 0.005068 0.012176 0.005634 0.002372 0.005603 0.011125
Nuclear Periphery 0.000175 0.000341 0.002112 0.001009 0.000290 0.000167 0.001142 0.000170 0.000222 0.000230 0.001694 0.000811
Nuclear Periphery Foci 0.000530 0.001539 0.001400 0.002302 0.001262 0.000661 0.002457 0.000031 0.000830 0.000977 0.001856 0.001767
Nucleolus 0.000433 0.001048 0.000227 0.000320 0.000375 0.000393 0.000205 0.000154 0.000409 0.000629 0.000218 0.000281
Nucleus 0.132474 0.060078 0.448250 0.152577 0.103062 0.048725 0.210307 0.138285 0.120412 0.052814 0.345589 0.149211
Peroxisomes 0.000813 0.001322 0.000115 0.002958 0.000852 0.004331 0.000158 0.000174 0.000829 0.003247 0.000134 0.002302
Vacuole 0.046265 0.090301 0.066266 0.090827 0.056716 0.077478 0.116214 0.009998 0.050551 0.082097 0.087816 0.071788
Vacuole Periphery 0.000635 0.002681 0.000142 0.007900 0.000688 0.001954 0.000124 0.002459 0.000657 0.002216 0.000134 0.006618

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.75 -4.83 -2.73 -2.56 -1.93 -1.95 -1.84 2.80 2.50 5.65 -2.35 -5.21 -2.60 -1.58 -1.89
Bud Neck 1.91 -1.07 -1.49 -2.74 -0.71 -5.30 0.09 -0.16 3.59 -0.20 -2.85 -0.72 -1.91 0.17 -1.34
Bud Site -2.71 -2.09 -6.99 -4.06 -4.87 -6.41 -0.45 -0.87 2.77 -0.61 -7.32 -1.97 -6.76 -1.77 -5.18
Cell Periphery 3.47 -4.50 -3.88 -5.99 1.06 3.59 -0.68 7.63 9.23 15.20 5.29 -4.02 -0.80 -5.09 2.82
Cytoplasm 0.23 43.76 29.40 23.13 -8.94 -1.33 19.66 -3.17 -2.22 -17.57 -0.54 44.18 23.62 22.08 -11.28
Cytoplasmic Foci -0.11 31.90 28.94 21.02 -7.37 3.74 29.21 31.30 31.30 10.89 1.24 42.81 41.20 35.78 -2.63
Eisosomes 6.34 6.33 8.52 1.57 2.54 3.03 1.98 12.26 13.32 19.14 5.81 5.63 12.13 6.20 8.93
Endoplasmic Reticulum -4.10 -20.04 -5.74 -1.32 13.47 2.56 -3.09 4.26 4.10 18.79 1.01 -13.70 -0.14 -1.51 17.03
Endosome -8.20 5.56 0.92 7.88 -1.93 -4.62 8.49 14.85 13.26 13.23 -9.51 9.78 4.37 11.12 -0.59
Golgi -1.54 6.26 -1.31 -0.17 -2.26 -4.47 7.27 0.47 3.94 -0.91 -4.72 9.15 -1.17 2.20 -2.40
Lipid Particles 0.49 1.28 -0.87 -1.14 -1.47 4.44 3.05 10.26 9.98 19.83 3.14 2.56 0.12 -1.10 -0.81
Mitochondria 0.24 1.03 -1.27 -1.38 -2.16 -2.33 1.29 0.52 3.18 -1.17 -1.85 1.66 -1.28 0.31 -2.56
Mitotic Spindle -2.37 -4.53 -9.12 -7.32 -7.10 -5.49 -4.30 -2.00 0.84 0.23 -5.57 -6.18 -9.40 -6.64 -6.88
None 5.17 3.29 -0.57 -6.09 -4.33 1.37 -4.62 -9.06 -10.28 -6.73 6.64 0.89 -5.15 -11.83 -6.96
Nuclear Periphery -3.05 -29.89 -16.68 -12.61 12.79 2.56 -19.65 -2.48 -6.09 18.22 -0.64 -35.22 -16.20 -16.02 14.72
Nuclear Periphery Foci -5.33 -8.61 -6.83 -0.39 1.37 2.53 -4.09 4.98 7.48 15.88 -0.95 -8.55 -2.66 -2.20 6.50
Nucleolus -2.03 4.74 0.25 2.04 -1.13 -0.37 1.94 1.83 2.25 -0.27 -2.00 3.80 0.59 2.13 -1.34
Nucleus 18.86 -44.01 -13.82 -24.79 26.24 15.57 -21.25 -10.44 -16.85 5.30 26.59 -44.67 -17.92 -31.23 21.64
Peroxisomes -2.04 5.12 0.65 2.32 -2.79 -6.15 8.09 6.95 7.58 0.46 -6.41 8.01 1.74 6.87 -2.72
Vacuole -10.83 -15.12 -24.24 -14.51 -11.36 -7.56 -19.41 4.14 9.17 19.78 -14.03 -24.22 -21.25 -13.77 -2.76
Vacuole Periphery -2.15 2.55 -1.44 0.91 -2.30 -2.40 3.41 -0.46 0.53 -0.98 -3.23 3.95 -1.48 0.89 -2.49
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Para-aminobenzoate (PABA) synthase; has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (90%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Abz1

Abz1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Abz1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available