Standard name
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.08 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0.13 0.09 0.1 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0.08 0.07 0.13 0.1 0.14 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.13 0.14 0.06 0.17 0.12 – 0 0.11 0.06 0 0.08 0.11 0.13 0 0 0 0.05 0 0.07 0.06 0.08 0.05
Golgi 0 0 0.2 0.05 0 0 0 – 0 0 0 0 0.39 0.36 0.33 0.27 0.52 0.52 0.05 0.07 0.05 0.05 0.06 0.07
Mitochondria 0.85 0.9 0.6 0.77 0.75 0.65 0.68 – 0.93 0.82 0.86 0.89 0.5 0.47 0.49 0.06 0.12 0.1 0.77 0.76 0.76 0.69 0.71 0.7
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.06 0.1 0 0 0 – 0 0.05 0 0 0.05 0 0.08 0.11 0.07 0 0 0 0.09 0.06 0.06 0.06
SpindlePole 0 0 0.1 0.05 0.1 0.07 0.08 – 0 0.05 0.06 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.17 0.15 0.09 0.09 0.11 0.17 0.15 – 0.05 0.1 0.08 0.08 0.14 0.11 0.11 0.18 0.15 0.19 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 8 12 4 3 1 1 – 1 0 2 0 3 9 0 4 6 9 5 7 4 5 9 23
Bud 4 9 8 10 13 10 8 – 21 20 26 35 0 2 1 10 4 1 2 1 0 0 2 1
Bud Neck 0 0 0 0 0 1 0 – 1 1 0 0 0 0 0 0 0 0 2 3 0 2 1 2
Bud Site 0 1 0 0 2 4 1 – 6 4 10 11 0 0 0 0 0 0 – – – – – –
Cell Periphery 11 47 18 14 2 15 5 – 7 11 16 20 14 8 9 30 26 32 1 1 0 1 1 1
Cytoplasm 7 11 8 15 24 20 24 – 15 12 18 21 10 19 23 31 29 45 1 3 0 3 0 1
Endoplasmic Reticulum 5 11 4 6 3 2 4 – 4 3 5 0 7 11 9 9 6 10 0 2 1 1 3 2
Endosome 10 12 61 66 25 132 95 – 11 96 55 34 22 27 41 7 4 3 22 23 43 19 31 19
Golgi 16 10 96 22 9 14 4 – 0 4 8 5 103 87 103 63 148 171 22 42 30 17 24 28
Mitochondria 330 521 288 378 326 512 528 – 980 697 790 846 131 114 155 14 35 33 327 465 500 216 292 300
Nucleus 8 6 3 5 15 16 21 – 12 13 14 19 2 1 1 6 5 4 0 3 0 5 1 0
Nuclear Periphery 15 6 4 3 5 25 21 – 38 17 29 15 3 2 0 9 6 7 3 2 4 2 2 3
Nucleolus 13 1 1 5 6 21 34 – 40 25 23 23 0 1 1 4 4 6 2 0 1 0 2 2
Peroxisomes 3 18 30 50 9 22 10 – 12 39 8 31 12 6 24 25 19 14 15 18 60 18 23 27
SpindlePole 8 6 50 24 42 55 59 – 29 46 59 48 11 11 6 7 1 4 2 1 2 2 2 2
Vac/Vac Membrane 66 87 45 42 46 136 118 – 57 88 71 79 38 27 34 43 42 64 13 33 3 13 12 8
Unique Cell Count 388 581 482 488 432 790 773 1051 855 921 949 263 244 314 234 285 329 426 614 660 316 414 430
Labelled Cell Count 500 754 628 644 530 986 933 1234 1076 1134 1187 356 325 407 262 335 403 426 614 660 316 414 430


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 5.5 6.9 6.4 5.7 6.1 5.9 – 4.9 5.6 5.3 5.2 7.1 7.0 6.9 9.6 12.5 12.0 7.5 7.6 7.9
Std Deviation (1e-4) 1.1 0.9 1.0 1.4 1.3 1.1 1.4 – 1.1 0.9 1.1 1.1 1.2 1.1 1.2 2.5 3.5 3.2 1.4 1.4 1.5
Intensity Change (Log2) – – – -0.09 -0.27 -0.18 -0.22 – -0.49 -0.29 -0.37 -0.39 0.05 0.04 0.01 0.48 0.87 0.8 0.14 0.15 0.21

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.0 -2.1 0 0 – 0 0 0 0 -1.3 0.9 0 -0.7 -0.3 0.2
Bud 0.4 1.4 -0.6 -1.0 – 0 0.8 1.3 2.1 0 0 0 2.1 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.8 -3.4 -2.0 -4.0 – 0 -3.0 -2.3 -1.8 1.0 -0.3 -0.7 4.6 3.1 3.5
Cytoplasm 1.4 3.2 1.0 1.6 – -0.3 -0.4 0.4 0.7 1.8 4.1 4.0 6.4 5.3 6.8
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 3.3 2.2 0 0 2.4
Endosome 0.4 -3.6 2.0 -0.2 – 0 -0.8 -4.3 -6.5 -1.8 -0.6 0.2 -4.1 -5.4 -6.1
Golgi -7.3 -8.4 -11.2 -12.3 – 0 -13.0 -12.9 -13.5 5.7 4.6 4.1 2.1 9.2 9.5
Mitochondria 5.9 5.1 1.8 3.1 – 0 8.7 11.0 13.0 -2.6 -3.3 -2.9 -13.7 -12.9 -14.2
Nucleus 0 3.1 2.0 2.6 – 0 1.4 1.5 2.0 0 0 0 0 0 0
Nuclear Periphery 0 0 2.7 2.3 – 0 1.6 2.7 1.2 0 0 0 0 0 0
Nucleolus 0 0 3.3 4.4 – 0 3.5 3.1 3.1 0 0 0 0 0 0
Peroxisomes 2.3 -3.1 -3.0 -4.8 – 0 -1.3 -5.9 -2.6 -0.9 -2.2 0.8 2.1 0.2 -1.2
SpindlePole -3.2 -0.3 -2.1 -1.7 – 0 -3.4 -2.6 -3.8 -2.9 -2.7 -4.6 -3.4 -5.4 -5.1
Vacuole -0.4 0.7 3.9 3.0 – -2.9 0.6 -1.1 -0.6 2.1 0.7 0.7 3.5 2.3 4.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8574 2.0468 2.0159 1.6389 1.8974 2.0292 7.4335 6.6147 7.1413 6.7162 7.3814 7.1967 3.2667 3.4286 3.4539 3.5932 3.0658 3.9398
Actin 0.0065 0.006 0.009 0.0012 0.0041 0.0036 0.0415 0.0102 0.0332 0.0604 0.0386 0.0312 0.0195 0.0037 0.0024 0.001 0.0015 0.0088
Bud 0.0021 0.0118 0.0106 0.0053 0.0332 0.0059 0.0014 0.0046 0.0038 0.001 0.0029 0.0013 0.0005 0.0009 0.0007 0.0006 0.0005 0.0018
Bud Neck 0.0006 0.0014 0.0138 0.0121 0.0009 0.0064 0.0014 0.0015 0.003 0.0012 0.0013 0.0025 0.0018 0.0007 0.0007 0.0009 0.0002 0.004
Bud Periphery 0.0021 0.0065 0.006 0.0091 0.0173 0.0039 0.0037 0.0107 0.0078 0.0017 0.0096 0.0038 0.0017 0.0022 0.0017 0.0025 0.0011 0.0017
Bud Site 0.0059 0.0557 0.0235 0.0034 0.0043 0.0019 0.0092 0.0279 0.0231 0.0033 0.0032 0.0025 0.0047 0.0058 0.0061 0.0007 0.0004 0.0015
Cell Periphery 0.0007 0.0013 0.0014 0.0004 0.0007 0.0007 0.0046 0.0021 0.0043 0.0003 0.0006 0.0013 0.0044 0.0022 0.0007 0.0005 0.0002 0.001
Cytoplasm 0.0102 0.0099 0.0136 0.0062 0.0156 0.0169 0.0481 0.0523 0.0213 0.0126 0.0067 0.0112 0.0098 0.0244 0.008 0.0072 0.0109 0.0115
Cytoplasmic Foci 0.0498 0.0514 0.0522 0.0547 0.0237 0.0795 0.0457 0.0587 0.0479 0.0616 0.0245 0.0223 0.0553 0.0454 0.0324 0.0421 0.0242 0.0363
Eisosomes 0.0003 0.0003 0.0005 0.0001 0.0001 0.0003 0.0014 0.0007 0.0013 0.0009 0.0008 0.0007 0.0041 0.0005 0.0005 0.0001 0.0002 0.0005
Endoplasmic Reticulum 0.004 0.0015 0.0014 0.001 0.0016 0.0034 0.0154 0.0088 0.0059 0.0029 0.0013 0.0023 0.0028 0.0014 0.0013 0.0008 0.0029 0.002
Endosome 0.1231 0.0875 0.088 0.092 0.0774 0.0718 0.1563 0.1784 0.1112 0.0728 0.1013 0.0959 0.0786 0.136 0.0733 0.0878 0.0712 0.0747
Golgi 0.0557 0.047 0.0373 0.0313 0.0386 0.0344 0.0493 0.0588 0.0917 0.041 0.039 0.0906 0.0719 0.0759 0.0497 0.042 0.0621 0.0547
Lipid Particles 0.0398 0.0161 0.0321 0.0055 0.0115 0.0248 0.021 0.013 0.0149 0.0124 0.0054 0.0183 0.0556 0.0101 0.0117 0.0053 0.0234 0.0205
Mitochondria 0.612 0.5956 0.6432 0.7246 0.7121 0.6744 0.4334 0.4448 0.5519 0.6422 0.7009 0.6573 0.582 0.6197 0.7204 0.761 0.7324 0.7098
None 0.0392 0.0556 0.0166 0.004 0.011 0.0104 0.0314 0.0478 0.0312 0.0082 0.0152 0.0233 0.0311 0.0085 0.026 0.0054 0.0322 0.0218
Nuclear Periphery 0.0025 0.0016 0.0019 0.0008 0.0014 0.0024 0.039 0.0051 0.0024 0.0019 0.0027 0.0036 0.0005 0.0006 0.0003 0.0003 0.0004 0.0009
Nucleolus 0.0016 0.0029 0.0026 0.0017 0.0018 0.0037 0.0018 0.0027 0.001 0.0003 0.001 0.0006 0.0011 0.0095 0.0005 0.0003 0.0002 0.0006
Nucleus 0.0011 0.004 0.0037 0.0012 0.0031 0.0047 0.0109 0.0035 0.0013 0.0008 0.0014 0.0011 0.0006 0.001 0.0006 0.0004 0.0002 0.0013
Peroxisomes 0.0201 0.0222 0.0248 0.0133 0.0107 0.0287 0.0468 0.0202 0.0266 0.0672 0.0127 0.0197 0.0649 0.0335 0.0467 0.0247 0.0272 0.0356
Punctate Nuclear 0.0015 0.0028 0.0064 0.001 0.0179 0.0102 0.0062 0.0031 0.001 0.002 0.001 0.001 0.0012 0.0007 0.0005 0.0001 0.0003 0.0003
Vacuole 0.0131 0.0129 0.0076 0.0198 0.0089 0.0067 0.0196 0.0339 0.0104 0.0024 0.0185 0.0051 0.0043 0.0102 0.0108 0.0102 0.0046 0.0063
Vacuole Periphery 0.008 0.0061 0.0039 0.0113 0.0041 0.0053 0.0119 0.0115 0.0046 0.0028 0.0112 0.0045 0.0037 0.007 0.0048 0.006 0.0037 0.0043

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.8892 20.4695 13.2906 12.7289 12.0609 10.0124 20.6967 19.2072 20.7356 19.402
Translational Efficiency 0.8221 0.6247 0.9095 1.0678 1.014 1.9776 1.0583 0.9339 1.0396 1.0004

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
475 1230 1969 805 2003 2316 1817 429 2478 3546 3786 1234

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 735.62 797.88 899.65 971.96 744.90 910.69 874.73 885.48 743.12 871.56 887.69 941.90
Standard Deviation 87.54 117.28 115.13 152.56 97.67 118.74 121.31 148.98 95.88 129.85 118.79 156.83
Intensity Change Log 2 — 0.117211 0.290403 0.401936 — 0.289913 0.231791 0.249413 — 0.206685 0.261211 0.327212

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000691 0.004022 0.006403 0.014545 0.000363 0.001212 0.002021 0.002320 0.000426 0.002187 0.004300 0.010295
Bud Neck 0.003037 0.004504 0.002960 0.004440 0.001968 0.001603 0.008774 0.002823 0.002173 0.002609 0.005750 0.003878
Bud Site 0.004346 0.011619 0.026465 0.033284 0.003791 0.005749 0.028291 0.015810 0.003897 0.007785 0.027341 0.027209
Cell Periphery 0.000673 0.000728 0.000278 0.001121 0.000265 0.000337 0.000475 0.000597 0.000343 0.000473 0.000372 0.000939
Cytoplasm 0.001030 0.002292 0.005081 0.003211 0.000706 0.001495 0.006664 0.002133 0.000769 0.001771 0.005841 0.002836
Cytoplasmic Foci 0.019153 0.031412 0.056957 0.026887 0.017899 0.018875 0.023832 0.024522 0.018139 0.023224 0.041060 0.026065
Eisosomes 0.000067 0.000084 0.000083 0.000132 0.000038 0.000057 0.000069 0.000061 0.000043 0.000067 0.000077 0.000108
Endoplasmic Reticulum 0.000446 0.000562 0.001660 0.001472 0.000456 0.000148 0.000817 0.000873 0.000454 0.000291 0.001255 0.001264
Endosome 0.035851 0.085593 0.079857 0.045962 0.039408 0.046097 0.089492 0.057666 0.038726 0.059797 0.084481 0.050031
Golgi 0.044798 0.074915 0.107196 0.076040 0.051645 0.073161 0.053052 0.063872 0.050333 0.073769 0.081211 0.071810
Lipid Particles 0.007614 0.004802 0.000911 0.000508 0.002821 0.000689 0.004100 0.002327 0.003740 0.002116 0.002441 0.001140
Mitochondria 0.836678 0.715475 0.534257 0.700354 0.840189 0.816938 0.632702 0.716076 0.839516 0.781743 0.581503 0.705820
Mitotic Spindle 0.002160 0.006070 0.074866 0.019662 0.002980 0.003605 0.036442 0.024979 0.002823 0.004460 0.056425 0.021510
None 0.000151 0.000327 0.000259 0.000330 0.000214 0.000217 0.000485 0.000361 0.000202 0.000255 0.000367 0.000341
Nuclear Periphery 0.000222 0.000166 0.000487 0.000401 0.000140 0.000033 0.000598 0.000980 0.000155 0.000079 0.000540 0.000602
Nuclear Periphery Foci 0.000161 0.000285 0.000584 0.000367 0.000161 0.000064 0.000804 0.000752 0.000161 0.000140 0.000690 0.000501
Nucleolus 0.000150 0.000408 0.000436 0.000131 0.000443 0.000175 0.002215 0.000512 0.000387 0.000256 0.001290 0.000264
Nucleus 0.000260 0.000437 0.000769 0.000192 0.000219 0.000111 0.002118 0.001952 0.000227 0.000224 0.001416 0.000804
Peroxisomes 0.027875 0.035680 0.033332 0.035205 0.014774 0.014375 0.024185 0.014896 0.017285 0.021765 0.028942 0.028145
Vacuole 0.003451 0.010434 0.038355 0.019396 0.007433 0.006365 0.050357 0.034388 0.006670 0.007776 0.044115 0.024608
Vacuole Periphery 0.011186 0.010186 0.028803 0.016358 0.014089 0.008695 0.032507 0.032099 0.013532 0.009212 0.030581 0.021830

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.14 -6.14 -6.36 -4.37 -3.46 -3.04 -3.99 -2.33 -1.26 -0.32 -4.31 -7.49 -6.78 -5.37 -3.89
Bud Neck -1.12 -0.11 -1.05 0.05 -1.35 0.58 -7.06 -1.12 -1.91 5.89 -0.73 -5.79 -2.18 -1.78 2.59
Bud Site -3.51 -10.34 -7.58 -5.73 -1.73 -2.04 -11.33 -3.28 -2.74 2.92 -4.29 -16.65 -8.65 -7.17 0.02
Cell Periphery -0.22 1.64 -1.48 -1.89 -4.50 -1.19 -3.81 -2.12 -1.57 -0.75 -1.86 -0.51 -4.20 -3.29 -4.18
Cytoplasm -2.25 -8.05 -4.60 -1.88 4.42 -2.53 -6.92 -3.31 -1.35 4.99 -3.75 -10.82 -7.66 -3.35 6.20
Cytoplasmic Foci -4.26 -12.93 -2.64 1.62 10.49 -0.66 -3.59 -2.09 -1.82 -0.06 -3.78 -14.34 -4.06 -1.47 7.22
Eisosomes -1.35 -1.35 -4.38 -4.77 -5.13 -6.35 -9.71 -2.79 -0.47 1.01 -6.61 -10.02 -9.01 -5.85 -4.39
Endoplasmic Reticulum -0.81 -4.95 -2.72 -2.42 0.60 1.81 -1.94 -1.62 -3.65 -0.27 1.13 -4.44 -2.88 -3.91 0.10
Endosome -8.65 -9.34 -2.04 7.50 8.20 -2.34 -12.32 -3.28 -2.09 5.07 -7.80 -16.02 -3.45 2.90 9.84
Golgi -5.13 -10.98 -4.54 -0.16 4.92 -5.58 -0.33 -1.68 1.27 -1.49 -7.29 -9.55 -4.55 0.43 1.93
Lipid Particles 1.19 3.12 3.33 4.48 2.62 4.32 -1.29 0.58 -2.35 1.59 2.44 1.73 4.20 2.30 2.62
Mitochondria 7.92 21.17 7.95 1.00 -11.40 2.92 20.65 7.16 5.86 -4.61 8.08 33.40 12.03 6.92 -10.98
Mitotic Spindle -4.93 -20.18 -8.70 -6.50 13.47 -1.01 -13.73 -4.90 -4.76 2.29 -3.14 -23.92 -9.11 -8.32 11.66
None -3.69 -5.00 -6.32 0.16 -2.76 -0.06 -6.29 -3.77 -2.72 2.95 -1.49 -6.19 -5.16 -2.18 1.41
Nuclear Periphery 0.46 -1.83 -0.65 -0.90 0.36 3.21 -3.45 -2.26 -2.56 -0.97 1.97 -4.32 -2.10 -2.47 -0.24
Nuclear Periphery Foci -1.73 -4.16 -1.57 -0.61 1.52 3.51 -4.12 -2.88 -3.38 0.28 0.64 -5.87 -3.12 -3.32 1.48
Nucleolus -1.80 -1.54 0.16 2.35 1.75 1.13 -3.01 -0.25 -1.62 2.95 0.70 -2.88 0.70 -0.03 3.55
Nucleus -0.93 -2.97 0.45 1.61 3.49 1.32 -4.69 -1.61 -1.71 0.32 0.03 -5.68 -1.53 -1.53 1.94
Peroxisomes -1.38 -1.08 -1.20 0.11 -0.37 0.21 -3.80 -0.02 -0.13 2.34 -2.14 -5.41 -3.34 -1.98 0.29
Vacuole -6.26 -17.78 -6.55 -3.55 6.58 1.41 -17.18 -6.23 -6.51 3.28 -1.64 -23.43 -8.12 -7.68 7.62
Vacuole Periphery 0.44 -6.66 -1.88 -3.26 5.36 5.01 -9.43 -4.68 -6.22 0.07 4.45 -11.85 -4.29 -7.08 4.17
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrx15

Mrx15


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrx15-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available