Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.13 0.08 0.21 0.24 0.15 0.37 0.42 0.4 0.47 0.47 0.53 0.51 0.48 0.78 0.92 0.11 0.16 0.09 0 0 0 0 0 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.05 0 0 0 0 0 0 0 0 0 0 0.1 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.29 0.05 0.05 0 0.06 0.09 0.16 0.05 0.13 0.1 0.17 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.25 0.22 0.32 0.36 0.26 0.23 0.15 0.19 0.16 0.1 0.1 0.09 0.06 0 0 0.42 0.38 0.43 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.58 0.75 0.55 0.55 0.7 0.6 0.51 0.52 0.52 0.54 0.47 0.54 0.45 0.2 0.09 0.53 0.55 0.57 0.81 0.81 0.89 0.81 0.82 0.79
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 1 1 1 1 1 0 0 0 0 0 0 1 0 0 1 2
Bud 2 0 0 0 0 1 5 5 4 7 4 4 1 1 0 0 0 0 6 8 2 11 23 16
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 1 0 0 0 0 0
Bud Site 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 24 14 38 36 42 105 152 149 184 151 138 141 207 606 714 53 47 35 1 1 0 11 21 32
Endoplasmic Reticulum 0 0 1 0 1 0 1 0 1 0 1 0 4 4 1 18 6 9 0 0 0 0 3 3
Endosome 0 9 6 5 7 3 1 7 2 4 0 1 43 31 9 18 9 7 7 6 5 10 22 19
Golgi 0 1 3 0 2 0 1 0 0 0 0 0 1 1 1 7 3 4 0 1 1 2 2 1
Mitochondria 52 8 9 6 16 26 56 18 50 33 44 26 6 1 1 7 10 8 4 2 1 3 10 12
Nucleus 46 37 57 54 75 65 53 70 61 33 26 26 27 18 9 200 116 162 8 7 4 6 16 5
Nuclear Periphery 4 0 2 1 1 1 4 0 1 3 3 0 1 0 0 4 0 2 1 1 2 2 4 4
Nucleolus 3 2 1 0 0 0 2 0 3 0 0 0 4 0 0 5 7 0 2 2 0 1 1 2
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 2 3 1 2 0 0 0 0 0 0 0 0
SpindlePole 1 0 2 3 0 2 0 2 0 0 0 1 9 9 3 4 7 2 1 0 1 9 13 14
Vac/Vac Membrane 105 128 97 84 199 170 183 193 202 173 121 149 193 159 72 251 167 214 161 159 175 266 584 453
Unique Cell Count 182 170 177 152 286 285 359 369 390 322 260 278 433 776 777 474 303 374 201 196 197 331 714 571
Labelled Cell Count 238 200 216 189 343 373 458 445 510 407 338 349 501 834 812 569 373 443 201 196 197 331 714 571


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 9.2 7.3 6.9 7.9 6.5 6.2 6.9 5.8 6.1 5.5 5.9 5.9 5.4 5.2 11.1 11.6 10.8 6.4 6.3 6.3
Std Deviation (1e-4) 2.8 4.5 2.7 2.6 2.6 2.9 2.8 2.7 2.7 2.6 2.4 2.3 1.8 1.5 1.5 5.2 5.5 5.1 2.4 2.1 1.9
Intensity Change (Log2) – – – -0.08 0.11 -0.16 -0.24 -0.08 -0.33 -0.25 -0.41 -0.31 -0.3 -0.44 -0.48 0.61 0.67 0.57 -0.19 -0.21 -0.22

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.5 -1.9 3.5 4.8 4.4 5.8 5.6 6.6 6.2 6.0 14.5 20.7 -3.4 -1.6 -3.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.2 0 0
Endosome -0.1 0 0 0 0 0 0 0 0 2.7 0.4 0 0.2 -0.3 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.5 0.2 1.6 3.5 -0.1 2.8 2.0 3.7 1.7 0 0 0 0 -1.0 -1.9
Nucleus 0.6 -1.4 -2.2 -4.7 -3.4 -4.5 -6.1 -5.8 -6.2 -8.4 -13.3 -14.7 2.3 1.3 2.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.1 3.2 1.0 -0.8 -0.5 -0.7 -0.2 -1.7 -0.3 -2.3 -9.3 -14.3 -0.4 0.1 0.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.3054 5.1282 3.9979 2.2602 2.1631 3.0567 1.0751 3.8964 4.2934 2.729 3.1627 3.9222 0.8408 7.0001 5.3789 3.7257 3.2588 4.19
Actin 0.0001 0.0002 0.0001 0 0.0001 0.0003 0.0274 0.0002 0.0111 0.0005 0 0.0134 0.0207 0.0004 0.0009 0.0049 0.0065 0.0004
Bud 0.001 0.0042 0.0009 0.0009 0.0007 0.0007 0.0007 0.0013 0.001 0.0008 0.0002 0.0005 0.0035 0.0023 0.0007 0.0008 0.0004 0.0006
Bud Neck 0.0009 0.0022 0.0029 0.0019 0.0023 0.0074 0.0018 0.0026 0.0023 0.0009 0.0008 0.0027 0.0035 0.0019 0.0048 0.0086 0.0016 0.0135
Bud Periphery 0.0028 0.0056 0.0027 0.0025 0.0027 0.0028 0.0019 0.0023 0.0031 0.0012 0.0005 0.0018 0.0054 0.0038 0.0022 0.0017 0.0012 0.0024
Bud Site 0.0013 0.0055 0.0029 0.0014 0.0017 0.0011 0.0022 0.008 0.0022 0.0047 0.0004 0.0008 0.0072 0.011 0.0022 0.0114 0.0009 0.0006
Cell Periphery 0.0043 0.0083 0.0069 0.0039 0.0087 0.0078 0.0025 0.0058 0.0065 0.0026 0.0027 0.0064 0.0041 0.0083 0.0097 0.0076 0.0079 0.0065
Cytoplasm 0.0029 0.0103 0.0024 0.0008 0.0008 0.0034 0.0095 0.0111 0.002 0.0011 0.0006 0.0009 0.0027 0.0069 0.0014 0.0009 0.0011 0.0015
Cytoplasmic Foci 0.0184 0.0132 0.0096 0.0065 0.0029 0.0104 0.0303 0.0101 0.0071 0.0196 0.0019 0.0035 0.0258 0.0091 0.0154 0.0098 0.0026 0.0041
Eisosomes 0 0 0 0 0 0 0.0002 0 0.0003 0 0 0.0001 0.0002 0 0 0.0002 0 0
Endoplasmic Reticulum 0.0018 0.002 0.0014 0.0006 0.0018 0.0013 0.0051 0.0027 0.0025 0.0006 0.0003 0.0011 0.0021 0.0022 0.0016 0.0006 0.0015 0.0022
Endosome 0.2013 0.0763 0.1255 0.1106 0.0681 0.1021 0.1989 0.1341 0.1003 0.1061 0.0715 0.1095 0.1629 0.091 0.0972 0.1402 0.1021 0.0893
Golgi 0.011 0.009 0.0097 0.0049 0.007 0.0092 0.016 0.0074 0.015 0.0134 0.0012 0.0091 0.02 0.0168 0.0126 0.0105 0.0065 0.0095
Lipid Particles 0.0449 0.0136 0.0397 0.012 0.0339 0.033 0.0556 0.0204 0.0478 0.022 0.005 0.0162 0.0385 0.0127 0.0335 0.0329 0.0076 0.0215
Mitochondria 0.0572 0.0118 0.0668 0.0148 0.0057 0.0223 0.0318 0.0102 0.061 0.0125 0.0012 0.0158 0.0368 0.0164 0.0454 0.0162 0.0034 0.0178
None 0.0072 0.0044 0.0002 0.0002 0.0001 0.0035 0.0074 0.0033 0.0004 0.0003 0 0.0001 0.008 0.0012 0.0003 0.0002 0.0007 0.0023
Nuclear Periphery 0.0032 0.0052 0.0054 0.0012 0.0038 0.0031 0.015 0.0043 0.0053 0.0013 0.0007 0.0016 0.0067 0.0038 0.0032 0.001 0.0149 0.0039
Nucleolus 0.0075 0.0098 0.0139 0.0074 0.0055 0.0129 0.0194 0.0055 0.0054 0.0043 0.0045 0.0038 0.015 0.0047 0.006 0.0074 0.0061 0.0064
Nucleus 0.0062 0.0151 0.0068 0.0036 0.0045 0.0095 0.0071 0.0045 0.0034 0.0027 0.0021 0.0038 0.009 0.0042 0.0029 0.0022 0.0037 0.0091
Peroxisomes 0.0098 0.0027 0.0038 0.0021 0.0008 0.0025 0.0178 0.001 0.0024 0.007 0.0004 0.0008 0.0086 0.0016 0.0045 0.0058 0.0011 0.0016
Punctate Nuclear 0.0007 0.0009 0.0002 0.0001 0.0002 0.0005 0.0152 0.0014 0.0003 0.0018 0 0.0001 0.0015 0.0001 0.0003 0.0002 0.0017 0.0001
Vacuole 0.4324 0.6307 0.5265 0.6355 0.6969 0.588 0.3935 0.5961 0.5337 0.6316 0.6899 0.6633 0.4324 0.5954 0.5321 0.5768 0.6821 0.6103
Vacuole Periphery 0.1852 0.169 0.1714 0.1891 0.1518 0.1781 0.1407 0.1676 0.1868 0.1651 0.2158 0.1446 0.1853 0.2062 0.2231 0.1601 0.1464 0.1963

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 97.3276 16.3435 6.4205 18.0195 73.2038 51.5927 15.5528 13.4494 11.13 84.5632
Translational Efficiency 1.371 1.5981 0.8472 0.6251 1.4084 2.7052 1.6104 0.8037 1.176 1.2486

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1360 769 1935 1542 1889 1199 162 102 3249 1968 2097 1644

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 813.42 920.75 729.80 917.38 786.08 907.39 925.51 1092.33 797.52 912.61 744.92 928.23
Standard Deviation 176.53 212.90 142.42 188.18 146.63 168.21 132.88 518.89 160.40 187.06 151.04 227.38
Intensity Change Log 2 — 0.178809 -0.156499 0.173519 — 0.207047 0.235572 0.474661 — 0.192756 0.049480 0.329366

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000230 0.000715 0.001171 0.003974 0.000079 0.000158 0.000811 0.001434 0.000142 0.000376 0.001143 0.003817
Bud Neck 0.019508 0.017753 0.096385 0.038399 0.020590 0.015058 0.051265 0.054501 0.020137 0.016111 0.092900 0.039398
Bud Site 0.044074 0.051409 0.190856 0.166671 0.029940 0.023493 0.061778 0.110789 0.035856 0.034401 0.180884 0.163204
Cell Periphery 0.009394 0.007186 0.000495 0.001230 0.006238 0.004225 0.000331 0.001266 0.007559 0.005382 0.000482 0.001232
Cytoplasm 0.023848 0.020710 0.211775 0.063385 0.016044 0.011304 0.086224 0.086298 0.019311 0.014979 0.202076 0.064806
Cytoplasmic Foci 0.011626 0.011658 0.031731 0.021618 0.005951 0.007355 0.034637 0.051765 0.008326 0.009036 0.031956 0.023489
Eisosomes 0.000081 0.000050 0.000052 0.000050 0.000038 0.000070 0.000084 0.000046 0.000056 0.000063 0.000054 0.000050
Endoplasmic Reticulum 0.004072 0.003169 0.002166 0.002079 0.004162 0.004866 0.003588 0.001185 0.004124 0.004203 0.002276 0.002024
Endosome 0.055162 0.055438 0.060799 0.105888 0.045207 0.046763 0.119287 0.120920 0.049374 0.050153 0.065317 0.106820
Golgi 0.005687 0.005554 0.006660 0.036542 0.002696 0.004492 0.004768 0.066633 0.003948 0.004907 0.006514 0.038409
Lipid Particles 0.001105 0.001465 0.001487 0.001420 0.001205 0.001233 0.002928 0.019509 0.001163 0.001324 0.001598 0.002543
Mitochondria 0.003951 0.005000 0.004677 0.010012 0.003759 0.007881 0.001744 0.004619 0.003840 0.006755 0.004450 0.009677
Mitotic Spindle 0.000312 0.000415 0.027711 0.019682 0.000618 0.002503 0.007884 0.027048 0.000490 0.001687 0.026179 0.020139
None 0.001265 0.000353 0.006564 0.000501 0.000464 0.000343 0.002590 0.000521 0.000800 0.000347 0.006257 0.000502
Nuclear Periphery 0.000150 0.000207 0.000840 0.000751 0.000124 0.000328 0.001480 0.002831 0.000135 0.000281 0.000889 0.000880
Nuclear Periphery Foci 0.000245 0.000344 0.001854 0.001109 0.000172 0.000402 0.003136 0.001993 0.000203 0.000380 0.001953 0.001164
Nucleolus 0.000733 0.001544 0.004289 0.001219 0.000607 0.001713 0.006421 0.001541 0.000660 0.001647 0.004454 0.001239
Nucleus 0.006183 0.006519 0.124947 0.015129 0.005321 0.012043 0.277605 0.013457 0.005682 0.009885 0.136740 0.015025
Peroxisomes 0.001263 0.003548 0.017696 0.008695 0.000874 0.000790 0.015266 0.014669 0.001037 0.001868 0.017508 0.009065
Vacuole 0.749651 0.719886 0.201511 0.461513 0.789284 0.785215 0.302356 0.383289 0.772694 0.759688 0.209301 0.456659
Vacuole Periphery 0.061459 0.087076 0.006334 0.040133 0.066626 0.069764 0.015818 0.035683 0.064463 0.076529 0.007067 0.039857

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.46 -5.72 -4.66 -3.62 -3.33 -1.22 -3.02 -4.44 -4.10 -1.37 -1.72 -7.15 -4.90 -4.46 -3.38
Bud Neck 0.66 -18.55 -6.81 -6.67 13.30 2.57 -3.15 -2.04 -2.65 0.56 2.42 -19.29 -7.47 -9.25 13.03
Bud Site -1.24 -18.72 -15.03 -12.59 1.86 1.91 -1.98 -3.51 -3.89 -2.02 0.48 -21.48 -17.59 -17.41 1.32
Cell Periphery 1.67 12.07 10.70 5.34 -2.72 2.67 9.68 7.34 5.63 -1.47 3.13 15.03 12.44 7.71 -2.88
Cytoplasm 0.71 -30.16 -13.59 -13.31 16.90 1.76 -6.69 -5.58 -5.78 -1.50 1.87 -32.43 -16.35 -16.95 15.95
Cytoplasmic Foci -0.04 -8.21 -4.22 -3.66 4.77 -1.04 -4.69 -2.77 -2.62 -0.42 -0.60 -12.46 -8.06 -6.94 4.31
Eisosomes 0.92 0.90 0.97 0.30 0.61 -2.38 -5.29 -2.76 0.82 2.84 -0.43 0.09 0.44 1.47 1.32
Endoplasmic Reticulum 2.54 5.98 5.76 3.22 0.83 -1.21 -0.77 4.04 3.85 2.83 -0.23 7.23 7.43 5.16 1.60
Endosome -0.03 0.41 -7.51 -6.55 -8.13 -0.42 -3.66 -1.86 -1.75 1.07 -0.25 -2.27 -9.85 -9.14 -7.35
Golgi 0.07 0.01 -9.29 -9.54 -9.65 -2.02 -0.86 -2.86 -2.71 -2.77 -1.35 -2.16 -10.72 -10.30 -10.06
Lipid Particles -0.72 -1.72 -1.12 0.16 0.48 -0.09 -3.18 -1.58 -1.58 -1.35 -0.56 -1.92 -1.81 -1.42 -0.98
Mitochondria -0.67 -0.57 -4.48 -2.37 -4.47 -2.94 3.23 0.36 2.52 -1.26 -2.78 -0.53 -4.84 -1.49 -4.61
Mitotic Spindle -1.28 -12.10 -8.96 -8.91 2.03 -1.81 -1.90 -3.25 -3.02 -2.37 -1.91 -12.10 -9.37 -8.63 1.49
None 1.33 -4.70 0.87 -2.26 6.91 0.78 -2.18 -1.77 -2.23 1.58 1.50 -6.45 0.38 -2.51 7.03
Nuclear Periphery -0.94 -13.06 -7.28 -6.07 1.54 -3.11 -8.45 -2.05 -1.89 -0.58 -3.13 -15.21 -7.11 -5.69 1.04
Nuclear Periphery Foci -1.93 -3.97 -4.44 -3.88 1.99 -3.67 -2.71 -3.14 -2.93 0.36 -4.11 -4.60 -5.43 -4.50 2.08
Nucleolus -2.28 -9.26 -3.15 0.63 7.88 -3.53 -3.87 -1.61 0.12 2.85 -4.17 -10.48 -4.69 1.16 8.39
Nucleus -0.32 -25.65 -8.52 -8.05 20.56 -3.16 -11.02 -4.11 -3.50 8.42 -2.91 -27.95 -10.16 -7.51 22.07
Peroxisomes -2.16 -10.43 -6.80 -2.26 4.85 0.36 -3.84 -2.86 -2.90 0.60 -1.95 -11.17 -7.58 -5.63 4.88
Vacuole 2.40 56.32 25.18 19.44 -24.36 0.45 20.87 11.33 11.07 -3.30 1.75 75.93 33.12 29.30 -24.24
Vacuole Periphery -4.56 18.46 7.35 10.18 -14.37 -0.71 12.39 7.69 7.73 -1.49 -3.47 28.14 10.91 12.50 -14.28
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene
Localization
Cell Percentages vacuole (86%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Csi2

Csi2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Csi2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available