Standard name
Human Ortholog
Description Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.07 0.05 0.07 0 – 0 0.05 0 0 0.05 0.13 0.14 0.15 0.16 0 0.11 0 0 0 0 0 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.06 0.13 0.05 0 0.09 – 0.1 0.1 0.08 0.08 0.11 0.06 0.06 0 0.19 0.15 0.11 0 0 0 0 0 0
Nucleus 0.86 0.79 0.64 0.79 0.74 0.61 – 0.55 0.55 0.6 0.56 0.59 0.69 0.56 0.56 0.55 0.73 0.59 0.75 0.7 0.53 0.4 0.33 0.36
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.56 0.63 0.61 0.54 0.5 0.66 – 0.66 0.67 0.69 0.73 0.7 0.44 0.58 0.5 0.42 0.39 0.46 0.22 0.28 0.32 0.41 0.48 0.36
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0.05 0.05 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 0 0 0 0 0 – 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Bud Neck 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Bud Site 1 0 1 1 1 1 – 12 4 11 5 12 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1 0 8 6 13 5 – 19 12 4 8 12 16 15 26 10 3 6 0 0 3 0 3 7
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 1 1 0 1 0 0 0 0 0 1 0 0
Endosome 0 0 0 0 0 0 – 2 0 0 0 0 1 0 2 0 1 0 0 0 2 1 2 1
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
Mitochondria 17 5 15 6 4 18 – 44 23 25 15 27 7 6 3 12 11 6 0 0 2 0 1 4
Nucleus 316 69 76 89 139 125 – 252 123 182 104 145 87 59 100 34 52 32 294 64 69 28 41 46
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0
Nucleolus 207 55 72 61 93 135 – 301 150 210 135 171 55 62 89 26 28 25 86 26 41 29 61 46
Peroxisomes 0 1 1 0 0 1 – 0 0 0 0 0 0 2 3 0 0 0 0 0 1 0 0 0
SpindlePole 1 0 0 0 0 1 – 0 0 0 0 0 0 1 2 0 0 0 1 0 1 2 3 2
Vac/Vac Membrane 0 0 0 0 1 0 – 0 1 1 2 0 1 5 12 0 2 0 10 0 2 3 6 12
Unique Cell Count 369 87 119 112 187 204 456 224 305 186 244 126 106 177 62 71 54 394 92 130 71 128 129
Labelled Cell Count 543 130 173 163 251 286 633 313 433 269 368 169 152 237 83 97 69 394 92 130 71 128 129


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 23.5 30.4 14.5 18.4 22.4 18.4 – 20.2 18.5 19.7 18.1 18.7 24.4 24.8 28.1 49.8 38.4 44.5 20.9 24.7 22.5
Std Deviation (1e-4) 8.9 11.8 6.7 9.2 10.9 8.4 – 10.6 10.1 8.7 10.2 11.4 16.4 17.5 21.6 29.1 24.0 31.7 14.0 12.1 13.7
Intensity Change (Log2) – – – 0.35 0.63 0.34 – 0.48 0.36 0.45 0.32 0.37 0.75 0.78 0.96 1.78 1.41 1.62 0.53 0.77 0.64

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000204060WT3HU80HU120HU1600204060WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 0.1 0 – -1.2 -0.5 0 -0.9 -0.7 1.6 1.8 2.1 2.0 0 0
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.9 -3.7 -1.1 – -0.9 -0.7 -1.4 -1.3 -0.4 -1.9 -1.8 -3.9 1.2 0.6 -0.3
Nucleus 2.6 2.0 -0.5 – -1.7 -1.6 -0.8 -1.4 -0.8 0.9 -1.3 -1.3 -1.2 1.3 -0.6
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -0.9 -1.8 1.0 – 1.1 1.2 1.6 2.2 1.8 -2.6 -0.3 -1.7 -2.4 -2.8 -1.7
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 22.27 17.8298 19.7008 19.6362 16.0848 17.8521 19.9717 13.9972 16.7947 16.9672 17.3763 15.6288 20.845 15.6244 18.6641 18.2413 10.791 16.3902
Actin 0.0097 0.0024 0.0063 0.0123 0.0026 0.0002 0.0147 0.005 0.0208 0.0001 0.0007 0.0012 0.0148 0 0 0.0002 0.1172 0
Bud 0.0003 0.0026 0 0.0001 0.0002 0 0.0004 0.0002 0.0004 0.0001 0.0002 0.0001 0.0002 0 0.0001 0 0.0017 0.0001
Bud Neck 0.0003 0.0002 0 0.0001 0.0005 0.0001 0.0003 0.001 0.0004 0.0001 0.0009 0.0002 0.0001 0 0 0.0011 0.0018 0.0003
Bud Periphery 0.0004 0.0032 0.0001 0.0001 0.0003 0 0.0003 0.0002 0.0006 0.0001 0.0003 0.0002 0.0003 0 0.0001 0 0.0029 0.0001
Bud Site 0.0004 0.0089 0.0001 0.0001 0.0004 0 0.0009 0.0009 0.0013 0.0002 0.0023 0.0001 0.0003 0 0.0003 0.0002 0.0088 0.0002
Cell Periphery 0.0002 0 0.0001 0.0001 0.0005 0 0.0003 0.0001 0.0003 0.0001 0.0006 0.0001 0.0004 0 0.0003 0 0.001 0
Cytoplasm 0.0004 0.0001 0.0001 0.0001 0.0025 0 0.0051 0.0002 0.001 0.0005 0.0014 0.0004 0.0006 0 0.0045 0 0.0143 0.0001
Cytoplasmic Foci 0.0095 0.0006 0.0008 0.0011 0.0104 0.002 0.0206 0.0023 0.0047 0.0028 0.0197 0.006 0.0133 0 0.0055 0.0071 0.0253 0.0092
Eisosomes 0.0001 0 0.0001 0.0001 0.001 0 0.0002 0 0.0001 0 0 0 0 0 0 0 0.001 0
Endoplasmic Reticulum 0.0004 0 0.0001 0.0003 0.0016 0.0001 0.0011 0.0002 0.001 0.0002 0.0006 0.0001 0.0001 0 0.0001 0 0.0052 0
Endosome 0.0048 0.0001 0.0009 0.0015 0.0083 0.0008 0.01 0.0025 0.0083 0.0007 0.0487 0.0012 0.0008 0 0.0028 0.0015 0.0649 0.0018
Golgi 0.0017 0.0001 0.0006 0.0015 0.0022 0.0002 0.0066 0.0024 0.0041 0.0002 0.0108 0.0013 0.0006 0 0.0004 0.0013 0.0236 0.0009
Lipid Particles 0.0065 0.0002 0.0027 0.0028 0.0224 0.0022 0.0172 0.0021 0.0051 0.0037 0.0248 0.01 0.0078 0 0.0088 0.0102 0.0322 0.0006
Mitochondria 0.0035 0.0003 0.0024 0.0037 0.0301 0.0044 0.0079 0.0017 0.0033 0.0017 0.0056 0.0102 0.0029 0.0001 0.0011 0.0011 0.031 0.0002
None 0.001 0 0.0002 0.0003 0.0121 0.0001 0.0037 0.0003 0.0027 0.001 0.0004 0.0003 0.001 0 0.0008 0 0.0115 0
Nuclear Periphery 0.0044 0.0002 0.0002 0.0007 0.0145 0.0023 0.0031 0.0014 0.0013 0.003 0.0011 0.0003 0.0006 0.0001 0.0001 0.0001 0.0739 0
Nucleolus 0.1685 0.0481 0.063 0.058 0.5211 0.2524 0.113 0.0533 0.0426 0.0364 0.5415 0.2337 0.1426 0.0461 0.0698 0.0203 0.3492 0.2244
Nucleus 0.7751 0.9319 0.921 0.9146 0.3373 0.7339 0.7686 0.9229 0.89 0.9425 0.3279 0.7269 0.8034 0.9535 0.9036 0.9426 0.1646 0.76
Peroxisomes 0.0031 0.0004 0.0004 0.0006 0.0132 0.0001 0.0108 0.0017 0.0048 0.0002 0.0036 0.0048 0.0018 0 0.0008 0.0139 0.0203 0.0011
Punctate Nuclear 0.0081 0.0005 0.0004 0.0005 0.0146 0.0006 0.0126 0.0007 0.0008 0.0043 0.0027 0.0017 0.0046 0.0001 0.0001 0.0003 0.0277 0.0008
Vacuole 0.0008 0.0001 0.0002 0.0005 0.0018 0.0001 0.0011 0.0005 0.0033 0.0007 0.0051 0.0005 0.0016 0 0.0006 0.0001 0.0146 0.0001
Vacuole Periphery 0.0009 0 0.0003 0.0008 0.0025 0.0003 0.0016 0.0003 0.0029 0.0015 0.001 0.0006 0.0019 0 0.0002 0 0.007 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 88.5448 158.3073 74.097 63.2726 90.0756 70.7966 137.2859 108.0326 91.9626 91.5424
Translational Efficiency 1.6003 1.7441 1.487 2.169 2.0249 2.0371 2.0492 2.3458 1.8635 1.8132

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1789 1235 287 1156 418 1980 1082 1384 2207 3215 1369 2540

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1445.86 2044.88 3145.03 2937.33 1385.66 1830.09 2899.00 2722.78 1434.46 1912.60 2950.58 2820.43
Standard Deviation 470.93 612.14 842.29 941.62 400.50 525.60 725.82 861.15 459.02 570.08 758.38 904.99
Intensity Change Log 2 — 0.500088 1.121146 1.022577 — 0.401341 1.064982 0.974507 — 0.452608 1.093934 0.999253

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000566 0.000732 0.001006 0.000994 0.000624 0.000666 0.000910 0.000746 0.000577 0.000691 0.000930 0.000859
Bud Neck 0.001800 0.004166 0.006641 0.005210 0.001846 0.003455 0.006153 0.005818 0.001809 0.003728 0.006256 0.005541
Bud Site 0.000706 0.000932 0.001238 0.001813 0.000379 0.001062 0.000813 0.001415 0.000644 0.001012 0.000902 0.001596
Cell Periphery 0.000127 0.000131 0.000033 0.000303 0.000016 0.000144 0.000021 0.000202 0.000106 0.000139 0.000023 0.000248
Cytoplasm 0.000837 0.000623 0.000052 0.001294 0.000052 0.000138 0.000025 0.000744 0.000689 0.000324 0.000031 0.000994
Cytoplasmic Foci 0.000817 0.001693 0.002026 0.005576 0.002995 0.002371 0.000665 0.002445 0.001230 0.002110 0.000950 0.003870
Eisosomes 0.000236 0.000257 0.000314 0.000113 0.000163 0.000294 0.000298 0.000121 0.000222 0.000280 0.000301 0.000118
Endoplasmic Reticulum 0.000411 0.000202 0.000177 0.000164 0.000239 0.000360 0.000118 0.000262 0.000378 0.000299 0.000130 0.000217
Endosome 0.000029 0.000276 0.000009 0.000307 0.000032 0.000073 0.000003 0.001258 0.000030 0.000151 0.000004 0.000825
Golgi 0.000041 0.000131 0.000126 0.000316 0.000268 0.000059 0.000041 0.001323 0.000084 0.000087 0.000058 0.000865
Lipid Particles 0.000009 0.000693 0.000008 0.000066 0.000127 0.000057 0.000002 0.000018 0.000032 0.000301 0.000004 0.000040
Mitochondria 0.000928 0.001420 0.002717 0.003306 0.002221 0.001433 0.001988 0.002934 0.001173 0.001428 0.002141 0.003104
Mitotic Spindle 0.000422 0.002193 0.000622 0.003466 0.000849 0.001917 0.000081 0.001312 0.000503 0.002024 0.000194 0.002293
None 0.004015 0.000657 0.000737 0.001555 0.000675 0.000898 0.000537 0.001516 0.003382 0.000806 0.000579 0.001534
Nuclear Periphery 0.000015 0.000040 0.000064 0.000243 0.000023 0.000061 0.000024 0.000345 0.000017 0.000053 0.000032 0.000299
Nuclear Periphery Foci 0.000224 0.000185 0.000010 0.000091 0.000336 0.000112 0.000002 0.000166 0.000245 0.000140 0.000003 0.000132
Nucleolus 0.102931 0.120577 0.136234 0.095781 0.177040 0.140061 0.097832 0.068625 0.116967 0.132576 0.105883 0.080984
Nucleus 0.876176 0.848635 0.781352 0.866606 0.785423 0.833570 0.866402 0.901185 0.858988 0.839357 0.848572 0.885447
Peroxisomes 0.008880 0.015721 0.066058 0.011474 0.026150 0.012451 0.023675 0.006962 0.012151 0.013707 0.032560 0.009015
Vacuole 0.000460 0.000366 0.000239 0.000593 0.000313 0.000430 0.000136 0.000985 0.000432 0.000405 0.000158 0.000806
Vacuole Periphery 0.000369 0.000368 0.000337 0.000728 0.000228 0.000387 0.000275 0.001617 0.000342 0.000380 0.000288 0.001212

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.58 -9.68 -7.43 -3.74 0.39 -0.72 -7.06 -3.30 -1.79 5.67 -3.13 -14.89 -9.25 -4.01 2.27
Bud Neck -6.25 -13.85 -10.77 -2.52 2.93 -4.72 -13.66 -12.57 -5.81 0.38 -7.59 -17.75 -16.66 -6.12 1.74
Bud Site -1.13 -2.97 -2.02 -1.55 -1.00 -2.57 -5.65 -3.76 -0.92 -2.25 -1.78 -1.87 -3.03 -1.73 -2.40
Cell Periphery -0.16 2.12 -1.50 -1.31 -2.33 -2.03 -1.64 -2.95 -0.77 -2.87 -0.63 2.34 -2.10 -1.49 -3.58
Cytoplasm 0.18 2.54 -1.21 -1.23 -2.25 -2.09 1.18 -3.05 -2.64 -3.20 1.02 2.63 -1.28 -2.11 -3.19
Cytoplasmic Foci -1.37 -2.47 -3.23 -2.59 -2.51 0.27 1.47 0.30 0.05 -2.13 -1.43 0.45 -2.97 -1.90 -3.69
Eisosomes -1.21 -3.94 8.30 11.86 10.90 -4.75 -10.71 3.49 6.37 16.27 -2.90 -6.21 8.54 9.40 20.43
Endoplasmic Reticulum 3.55 4.38 4.50 0.99 0.80 -0.79 2.59 -0.25 0.67 -2.52 0.62 6.01 3.04 0.86 -2.67
Endosome -2.02 2.24 -1.58 0.08 -1.69 -0.93 1.87 -2.27 -2.18 -2.34 -2.28 3.44 -2.63 -2.09 -2.72
Golgi -2.02 -7.37 -1.82 -1.13 -1.16 1.53 1.67 -1.90 -2.43 -2.48 -0.15 0.83 -2.68 -2.67 -2.78
Lipid Particles -1.61 0.20 -1.81 1.47 -1.85 0.72 1.36 1.18 1.60 -2.72 -1.64 1.58 -0.43 1.59 -2.47
Mitochondria -4.30 -11.97 -6.94 -5.26 -1.47 0.65 0.16 -0.57 -3.98 -2.91 -1.01 -4.37 -6.08 -6.24 -3.91
Mitotic Spindle -1.69 -0.53 -2.77 -1.01 -2.69 -0.96 1.06 -0.63 0.53 -2.97 -2.22 0.88 -2.96 -0.56 -3.98
None 4.28 4.16 2.99 -4.19 -3.82 -1.75 3.71 -2.67 -1.81 -3.06 4.03 4.41 2.74 -3.45 -4.82
Nuclear Periphery -2.81 -3.21 -6.73 -5.77 -4.70 -2.14 -0.35 -1.65 -1.43 -1.64 -3.21 -4.23 -2.69 -2.31 -2.53
Nuclear Periphery Foci -0.01 1.08 0.57 0.71 -3.14 1.09 1.72 0.85 -0.25 -1.35 0.48 1.48 0.65 0.31 -2.09
Nucleolus -3.18 -4.48 0.97 3.58 4.78 4.04 8.37 11.71 12.54 4.99 -3.59 1.69 7.84 11.66 5.27
Nucleus 4.28 8.08 1.99 -1.75 -6.58 -4.36 -6.95 -10.12 -9.57 -4.66 3.97 2.40 -4.13 -8.11 -5.84
Peroxisomes -5.11 -9.35 -2.51 2.70 8.87 5.73 0.62 7.84 4.99 8.97 -1.69 -10.26 2.98 5.06 11.76
Vacuole 0.44 2.20 -0.83 -1.10 -2.03 -0.75 1.44 -1.99 -1.63 -2.82 0.02 3.52 -1.92 -1.93 -3.61
Vacuole Periphery -0.02 0.39 -1.96 -2.01 -2.17 -4.51 -1.96 -2.41 -2.11 -2.32 -0.78 1.09 -2.67 -2.57 -2.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling
Localization
Cell Percentages nucleus (87%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Htz1

Htz1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Htz1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available