Standard name
Human Ortholog
Description Protein of unknown function; localizes to the bud neck and cytoplasm; interacts with Nap1p; may interact with ribosomes, based on co-purification experiments; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.13 0.23 0.16 0 0.1 0.08 0 0 0 0 0 0 0.14 0.08 0 0.1 0.13 0 0.11 0.11 0.09 0.12 0.13 0.09
Bud 0.08 0 0.05 0 0.06 0.12 0.07 0.07 0.11 0 0.1 0.05 0 0 0 0 0 0.05 0.1 0.18 0.1 0.11 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.18 0.19 0.18 0.15 0.11 0.07
Bud Site 0.07 0.09 0.05 0 0 0.12 0 0 0 0 0 0 0 0 0 0.05 0 0 – – – – – –
Cell Periphery 0 0.06 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0
Cytoplasm 0.7 0.66 0.7 0.73 0.61 0.43 0.59 0.56 0.49 0.52 0.43 0.42 0.79 0.86 0.92 0.66 0.62 0.64 0.51 0.41 0.45 0.51 0.57 0.6
Endoplasmic Reticulum 0 0.05 0 0 0.06 0.08 0 0 0.05 0 0 0 0 0.05 0 0.06 0.09 0.05 0 0 0 0 0.08 0.11
Endosome 0 0 0 0.06 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0
Mitochondria 0.1 0.05 0.05 0.12 0 0.19 0.27 0.34 0.5 0.52 0.61 0.59 0 0 0 0 0 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Peroxisomes 0 0 0.05 0 0.06 0.06 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.07 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 0.06 0 0.05 0.06 0 0 0 0 0.06 0.07 0.09 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 18 46 21 3 18 17 13 15 6 4 3 4 29 35 16 13 6 1 15 26 13 18 47 31
Bud 11 6 7 3 12 25 21 28 26 15 25 13 7 14 5 4 1 3 14 42 14 17 14 7
Bud Neck 2 1 2 0 4 6 3 3 2 6 5 4 0 0 0 1 1 1 27 44 25 23 37 24
Bud Site 10 18 7 2 8 24 9 9 6 9 7 9 4 1 1 6 0 0 – – – – – –
Cell Periphery 5 13 4 0 1 2 6 16 5 6 11 10 5 18 21 6 3 2 5 2 2 0 3 3
Cytoplasm 97 133 90 66 115 87 178 233 120 199 105 118 159 357 435 83 28 37 76 98 64 78 202 218
Endoplasmic Reticulum 3 11 5 3 12 16 13 11 12 13 3 8 9 22 21 7 4 3 3 4 5 4 28 39
Endosome 6 2 3 5 14 16 12 11 2 7 3 2 1 2 0 3 0 3 3 8 5 4 6 6
Golgi 0 0 0 0 1 0 0 1 0 1 0 0 0 0 1 6 3 2 0 1 0 0 1 0
Mitochondria 14 10 6 11 8 39 82 142 123 202 149 165 3 1 2 5 2 4 2 2 2 0 5 6
Nucleus 0 0 1 0 1 0 0 3 2 2 0 2 0 1 3 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 2 1 1 1 7 8 8 12 6 12 8 9 0 0 0 2 2 3 0 0 0 0 0 0
Peroxisomes 6 9 7 4 12 13 11 8 7 9 8 6 9 0 2 8 1 1 0 0 0 0 0 0
SpindlePole 2 1 1 6 5 10 10 8 3 6 3 4 1 1 1 3 0 0 0 0 2 1 1 0
Vac/Vac Membrane 0 2 1 2 6 5 16 26 10 18 14 12 1 0 0 8 3 5 0 4 3 1 4 15
Unique Cell Count 139 202 129 90 189 202 302 416 244 385 243 278 201 417 473 125 45 58 150 240 142 155 357 362
Labelled Cell Count 176 253 156 106 224 268 382 526 331 512 344 366 228 452 508 155 54 65 150 240 142 155 357 362


Bud Neck, Cell Periphery, Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.6 8.4 7.3 7.0 7.6 6.7 6.1 6.1 5.4 5.1 4.9 4.8 8.6 8.0 7.9 12.5 13.6 15.0 8.4 8.4 8.6
Std Deviation (1e-4) 1.1 1.3 1.1 1.2 1.4 1.2 1.4 1.1 1.2 1.0 0.9 0.9 1.2 1.2 1.1 3.6 3.6 4.4 1.2 1.4 1.3
Intensity Change (Log2) – – – -0.07 0.05 -0.13 -0.26 -0.27 -0.44 -0.52 -0.57 -0.62 0.23 0.13 0.11 0.77 0.89 1.03 0.19 0.19 0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.0 -1.8 -2.2 -4.2 -5.1 -4.9 -7.0 -5.6 0 -0.5 -2.6 -5.4 -1.4 -0.5 -2.9
Bud 0 0.3 2.1 0.6 0.5 1.7 -0.7 1.6 0 -0.9 0 0 -0.9 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 -0.5 2.0 0 0 0 0 0 0 0 0 0 -0.2 0 0
Cell Periphery 0 0 0 0 0 0 0 0.7 0 0 0.6 0.7 0 0 0
Cytoplasm 0.6 -1.6 -4.7 -2.1 -2.8 -3.8 -3.6 -4.9 -5.1 1.9 4.1 6.7 -0.6 -0.9 -0.8
Endoplasmic Reticulum 0 1.0 1.5 0.2 0 0.5 0 0 0 0.3 0.6 0.3 0.6 0 0
Endosome 0 2.0 2.1 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.1 -0.2 3.8 5.3 6.6 8.8 9.6 10.6 0 0 0 0 -0.3 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0.3 0.4 -0.8 0 0 0 -1.0 0 -0.4 0 0 0.3 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 2.2 2.5 0 0 2.3 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.4788 4.0904 3.7638 3.3049 3.2665 4.7442 2.4347 4.2166 3.1658 3.0801 2.642 4.0792 3.0786 4.1529 3.8626 3.3773 3.7939 5.2617
Actin 0.135 0.0133 0.0195 0.0109 0.0942 0.0319 0.0979 0.0379 0.0308 0.018 0.055 0.0303 0.0012 0.004 0.0659 0.1547 0.0058 0.0069
Bud 0.0029 0.0021 0.0031 0.001 0.0044 0.0011 0.0019 0.0048 0.0046 0.0012 0.001 0.0013 0.0004 0.0003 0.0025 0.0014 0.0018 0.0013
Bud Neck 0.0489 0.0063 0.0622 0.013 0.043 0.66 0.0613 0.0059 0.0534 0.0809 0.002 0.6314 0.2352 0.0017 0.0611 0.1952 0.2308 0.692
Bud Periphery 0.0047 0.0015 0.006 0.0013 0.0102 0.0019 0.0019 0.0027 0.0039 0.0017 0.0019 0.0021 0.0002 0.0001 0.0025 0.0014 0.0016 0.0012
Bud Site 0.177 0.2977 0.1306 0.009 0.0052 0.0064 0.1961 0.2347 0.0318 0.0014 0.0022 0.0035 0.0989 0.3429 0.0649 0.118 0.01 0.0062
Cell Periphery 0.0158 0.0038 0.0041 0.0118 0.0007 0.0043 0.0054 0.003 0.0022 0.0004 0.0003 0.0009 0.0015 0.0007 0.0033 0.0008 0.0021 0.0009
Cytoplasm 0.3869 0.5928 0.6634 0.7101 0.7699 0.2474 0.4451 0.6182 0.7137 0.6894 0.7616 0.3151 0.652 0.6069 0.6925 0.3311 0.7218 0.2546
Cytoplasmic Foci 0.091 0.0076 0.0203 0.0451 0.0091 0.0194 0.0584 0.0187 0.0198 0.0211 0.0099 0.0067 0.0016 0.0212 0.0151 0.012 0.0136 0.0048
Eisosomes 0.0013 0.0002 0.0002 0.0003 0.0006 0.0001 0.0005 0.0001 0.0004 0 0.001 0 0 0 0.0003 0.0012 0 0
Endoplasmic Reticulum 0.0231 0.0027 0.0032 0.0059 0.0072 0.0025 0.0057 0.0009 0.0059 0.0029 0.0142 0.0029 0.0019 0.0038 0.0058 0.0013 0.0012 0.0042
Endosome 0.0344 0.0009 0.0099 0.014 0.0076 0.0027 0.0228 0.0118 0.023 0.0124 0.0217 0.0015 0.0008 0.0054 0.0138 0.0086 0.0038 0.0017
Golgi 0.0142 0.001 0.0062 0.0084 0.0064 0.0026 0.0182 0.0136 0.0055 0.0063 0.0128 0.0013 0.0002 0.0022 0.0311 0.0337 0.0026 0.001
Lipid Particles 0.015 0.0005 0.0022 0.0168 0.0019 0.0008 0.0111 0.0002 0.0027 0.0016 0.0098 0.0001 0.0001 0.0009 0.0033 0.0069 0.0001 0
Mitochondria 0.0032 0.0001 0.0012 0.002 0.0101 0.0003 0.0094 0.0296 0.0272 0.0521 0.0907 0.0001 0 0.0001 0.0142 0.1195 0.0003 0.0001
None 0.0192 0.0663 0.0607 0.1155 0.0221 0.0127 0.0279 0.0141 0.0557 0.0639 0.0023 0.0009 0.0032 0.0065 0.0055 0.0028 0.0018 0.024
Nuclear Periphery 0.0068 0.0004 0.0005 0.0008 0.0014 0.0001 0.0006 0.0002 0.0011 0.0004 0.0026 0.0001 0.0003 0.0007 0.0033 0.0002 0.0001 0.0001
Nucleolus 0.0008 0.0002 0.0001 0.0006 0.0001 0.0001 0.0033 0.0001 0.0002 0 0.0002 0.0001 0.0001 0.0001 0.0007 0.0001 0 0.0001
Nucleus 0.0013 0.0008 0.0007 0.0015 0.0008 0.0004 0.0015 0.0005 0.0009 0.0005 0.0007 0.0003 0.0006 0.0006 0.0031 0.0002 0.0005 0.0002
Peroxisomes 0.0053 0.0001 0.0031 0.02 0.0028 0.0036 0.0247 0.0013 0.0106 0.0431 0.0051 0.0006 0 0.0002 0.0059 0.0097 0.0003 0.0001
Punctate Nuclear 0.0066 0.0004 0.0006 0.0022 0.0005 0.0004 0.0029 0.0003 0.0006 0.0003 0.0008 0.0002 0.0003 0.001 0.0025 0.0003 0.0001 0.0001
Vacuole 0.0053 0.0011 0.0018 0.0092 0.0013 0.0011 0.003 0.0012 0.0054 0.0018 0.0025 0.0004 0.0017 0.0007 0.0021 0.0005 0.0013 0.0004
Vacuole Periphery 0.0013 0.0001 0.0002 0.0006 0.0006 0.0002 0.0004 0.0001 0.0008 0.0006 0.0015 0.0001 0.0001 0.0001 0.0006 0.0006 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.7921 25.5436 50.0592 64.0798 36.0978 16.1099 45.0319 65.7036 66.2604 33.8108
Translational Efficiency 3.281 3.1163 2.3111 1.8049 1.5676 1.6336 1.854 1.6652 1.6327 1.7753

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
380 861 263 900 1983 669 1649 1911 2363 1530 1912 2811

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 848.69 888.14 1318.83 1314.53 917.06 955.14 1189.97 1186.51 906.07 917.44 1207.69 1227.50
Standard Deviation 96.11 196.21 136.34 199.43 112.62 129.03 143.74 207.24 112.96 173.35 149.48 213.31
Intensity Change Log 2 — 0.065549 0.635949 0.631237 — 0.058696 0.375837 0.371636 — 0.061994 0.506716 0.502247

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001229 0.002924 0.020905 0.007784 0.003308 0.004456 0.003945 0.002052 0.002974 0.003594 0.006278 0.003887
Bud Neck 0.150029 0.048301 0.098263 0.047765 0.125563 0.098325 0.071808 0.088039 0.129497 0.070175 0.075447 0.075145
Bud Site 0.315555 0.332931 0.626537 0.567444 0.379444 0.341484 0.584318 0.407578 0.369170 0.336671 0.590126 0.458762
Cell Periphery 0.001504 0.000637 0.001545 0.001786 0.001328 0.000784 0.000870 0.001105 0.001356 0.000701 0.000963 0.001323
Cytoplasm 0.335162 0.403579 0.121994 0.322408 0.342755 0.346322 0.289410 0.344109 0.341534 0.378543 0.266381 0.337161
Cytoplasmic Foci 0.127366 0.108398 0.057323 0.015568 0.089141 0.096558 0.020735 0.025074 0.095288 0.103221 0.025768 0.022031
Eisosomes 0.000362 0.000090 0.000186 0.000124 0.000267 0.000186 0.000045 0.000077 0.000282 0.000132 0.000064 0.000092
Endoplasmic Reticulum 0.001075 0.001992 0.000617 0.000325 0.002325 0.000965 0.000703 0.000666 0.002124 0.001543 0.000691 0.000557
Endosome 0.015827 0.026451 0.005795 0.002741 0.011329 0.021955 0.002400 0.005902 0.012052 0.024485 0.002867 0.004890
Golgi 0.008333 0.009340 0.000929 0.001878 0.009638 0.009159 0.001328 0.000682 0.009428 0.009261 0.001273 0.001065
Lipid Particles 0.001844 0.001794 0.002732 0.001298 0.001189 0.002586 0.000415 0.000670 0.001295 0.002140 0.000734 0.000871
Mitochondria 0.001943 0.001917 0.000036 0.001391 0.001441 0.001195 0.000388 0.000215 0.001521 0.001601 0.000340 0.000591
Mitotic Spindle 0.000282 0.001656 0.002582 0.004100 0.000907 0.001854 0.000726 0.001851 0.000806 0.001742 0.000981 0.002571
None 0.000266 0.002120 0.000034 0.000078 0.000209 0.000170 0.000098 0.001558 0.000218 0.001268 0.000089 0.001084
Nuclear Periphery 0.000018 0.000087 0.000054 0.000038 0.000017 0.000026 0.000012 0.000030 0.000017 0.000060 0.000018 0.000033
Nuclear Periphery Foci 0.000687 0.000596 0.003029 0.000359 0.000266 0.000336 0.000163 0.000286 0.000334 0.000482 0.000557 0.000309
Nucleolus 0.000128 0.000478 0.000039 0.000154 0.000078 0.000345 0.000041 0.000196 0.000086 0.000420 0.000041 0.000182
Nucleus 0.005948 0.006252 0.002278 0.000798 0.002278 0.004728 0.000767 0.008306 0.002869 0.005586 0.000975 0.005902
Peroxisomes 0.003558 0.004907 0.012162 0.002979 0.003140 0.005236 0.002964 0.004188 0.003207 0.005051 0.004229 0.003801
Vacuole 0.027432 0.041804 0.042819 0.019521 0.022405 0.060280 0.018053 0.106874 0.023214 0.049883 0.021459 0.078906
Vacuole Periphery 0.001451 0.003746 0.000144 0.001462 0.002972 0.003049 0.000811 0.000540 0.002728 0.003442 0.000719 0.000835

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.21 -6.48 -6.21 -4.29 3.86 -0.73 -1.17 3.30 1.58 4.21 -0.79 -5.09 -1.99 -0.39 3.33
Bud Neck 7.87 4.17 8.28 0.45 4.36 3.21 9.39 6.99 1.92 -2.65 9.86 10.36 11.05 -0.27 0.53
Bud Site -0.85 -10.01 -12.33 -14.44 0.69 2.68 -19.25 -0.70 -3.10 17.53 3.18 -21.71 -7.64 -9.86 14.40
Cell Periphery 2.23 -0.01 -0.65 -7.57 -1.17 3.80 3.09 1.15 -1.38 -0.90 5.34 2.78 0.35 -4.06 -2.03
Cytoplasm -3.72 9.33 0.06 4.72 -11.27 -0.26 4.91 -1.37 -0.72 -6.08 -3.62 7.37 -0.91 2.90 -8.43
Cytoplasmic Foci 1.97 6.38 13.35 17.46 7.73 -1.20 19.81 18.17 12.62 -2.38 -1.69 20.66 22.95 20.68 1.96
Eisosomes 3.45 2.32 2.98 -1.32 1.80 2.27 9.77 8.31 3.92 -4.71 5.69 9.52 8.06 2.75 -3.11
Endoplasmic Reticulum -1.66 1.18 3.12 3.28 2.57 2.34 2.45 2.83 1.19 0.13 1.06 2.51 3.24 3.07 0.48
Endosome -3.12 3.74 5.43 9.02 3.12 -4.63 11.36 6.02 7.25 -6.38 -6.69 11.81 8.49 11.19 -3.94
Golgi -0.77 8.76 5.89 6.24 -1.22 0.35 13.51 14.78 6.40 4.24 0.20 15.26 14.64 9.92 0.92
Lipid Particles 0.14 -2.09 1.00 0.67 2.58 -1.07 4.63 2.88 1.44 -3.32 -1.36 2.55 2.06 1.91 -0.84
Mitochondria 0.02 1.82 0.42 0.51 -1.23 0.71 3.16 5.65 3.58 0.70 -0.19 3.58 2.30 2.24 -0.56
Mitotic Spindle -2.19 -4.27 -2.42 -1.43 -0.47 -1.06 0.37 -1.92 -0.05 -2.58 -1.63 -0.96 -2.83 -1.11 -2.51
None -1.54 3.82 2.84 1.70 -0.66 0.85 2.64 -2.78 -2.86 -3.01 -1.55 3.40 -2.61 0.30 -3.00
Nuclear Periphery -2.84 -4.20 -1.30 1.66 2.77 -1.59 0.78 -4.40 -1.26 -4.86 -3.14 -2.02 -3.25 1.65 -1.30
Nuclear Periphery Foci 0.49 -4.55 1.04 1.99 5.70 -0.66 2.23 -1.08 0.25 -3.00 -1.40 -3.27 -0.01 1.65 3.68
Nucleolus -1.87 3.67 -0.23 1.62 -1.28 -1.15 2.50 -2.88 0.59 -3.67 -2.29 3.43 -2.50 1.54 -3.58
Nucleus -0.18 1.77 6.05 3.92 4.89 -1.85 9.25 -7.77 -2.61 -9.53 -2.83 7.54 -5.78 -0.65 -8.60
Peroxisomes -2.13 -4.34 1.02 4.20 4.81 -2.37 0.46 -2.01 1.18 -2.01 -3.89 -2.00 -1.52 2.43 0.66
Vacuole -3.50 -4.84 0.87 4.58 5.21 -7.33 1.78 -19.30 -8.15 -19.47 -8.86 -1.57 -17.98 -8.40 -15.43
Vacuole Periphery -4.96 7.49 0.06 3.01 -1.94 -0.13 5.16 6.28 5.88 1.67 -1.59 5.66 4.96 7.11 -0.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; localizes to the bud neck and cytoplasm; interacts with Nap1p; may interact with ribosomes, based on co-purification experiments; potential Cdc28p substrate
Localization
Cell Percentages cytoplasm (71%), bud neck (8%), mixed (18%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Nba1

Nba1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nba1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available