Standard name
Human Ortholog
Description Nuclear pore-associated protein; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; contains a PAM domain implicated in protein-protein binding
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.1 0.05 0 0.05 0.06 0 0 0 0 0.11 0.2 0.22 0.1 0.13 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.06 0 0 0 0 0 0
Endosome 0 0 0.19 0.12 0.09 0 0 0 0 0 0 0 0.3 0.24 0.24 0.29 0.23 0.25 0.15 0.18 0.18 0.14 0.15 0.19
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.82 0.47 0.51 0.57 0.7 0.83 0.85 0.82 0.84 0.88 0.92 0.89 0.07 0 0 0.12 0.18 0.12 0.05 0.09 0 0.06 0.09 0.09
Nucleus 0 0 0 0.09 0.11 0.06 0.05 0.07 0.06 0 0.05 0.08 0.05 0 0.06 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.54 0.51 0.46 0.34 0.22 0.24 0.18 0.15 0.22 0.22 0.16 0.17 0.34 0.38 0.27 0.55 0.39 0.5 0.67 0.54 0.61 0.59 0.57 0.54
Nucleolus 0.19 0.1 0.09 0.06 0 0.07 0.09 0.06 0.08 0.08 0.06 0.08 0 0 0 0.26 0.08 0.12 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.06 0.05 0 0 0 0 0.05 0.05 0 0
Vac/Vac Membrane 0.11 0.3 0.11 0.06 0.13 0 0.06 0.05 0 0.06 0 0.07 0.24 0.31 0.31 0.31 0.37 0.32 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2 4 4 2 3
Bud 0 0 3 2 2 11 18 13 9 13 10 9 0 0 1 0 0 0 0 2 4 5 6 1
Bud Neck 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 1 0 1 11 11 6 8 10 17 9 0 2 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1 2 14 17 12 21 30 29 15 17 10 7 42 108 130 6 21 15 0 0 0 6 6 1
Endoplasmic Reticulum 3 3 5 0 4 1 1 0 0 0 1 0 3 1 3 3 8 10 0 0 3 1 1 2
Endosome 5 4 70 19 24 12 5 18 14 6 4 6 111 129 139 17 36 38 33 42 78 83 88 108
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 5 3 7 11
Mitochondria 173 94 189 93 186 413 508 422 345 454 410 457 25 7 20 7 28 19 11 22 19 37 57 49
Nucleus 4 6 10 14 28 32 28 37 26 19 23 42 19 23 32 0 6 6 2 5 2 13 14 6
Nuclear Periphery 113 102 171 55 59 119 110 76 91 112 72 86 127 206 157 32 61 77 147 128 268 347 344 314
Nucleolus 39 21 34 10 8 35 53 32 31 40 27 40 9 8 10 15 12 19 3 7 6 18 10 10
Peroxisomes 0 0 5 4 1 8 2 6 4 3 0 2 16 7 22 0 0 3 2 2 9 6 10 18
SpindlePole 2 2 15 7 8 13 14 16 17 6 10 12 20 28 35 3 3 3 8 7 23 30 26 23
Vac/Vac Membrane 24 61 41 10 35 19 35 24 16 31 20 35 90 168 177 18 58 50 6 13 4 21 17 19
Unique Cell Count 210 200 372 164 265 496 600 514 413 516 448 516 369 543 579 58 157 155 221 240 443 589 606 578
Labelled Cell Count 364 295 560 232 368 695 815 679 576 711 604 705 463 687 727 101 233 240 221 240 443 589 606 578


Nuclear Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 5.6 5.1 5.0 4.8 4.1 4.0 4.1 3.9 3.7 3.5 3.6 6.7 6.6 6.3 6.5 6.7 6.9 6.8 6.9 7.2
Std Deviation (1e-4) 0.6 0.9 1.1 2.0 1.8 1.2 1.4 1.4 1.3 0.9 1.2 0.9 1.1 1.2 1.2 1.0 1.4 1.3 1.1 1.3 1.3
Intensity Change (Log2) – – – -0.05 -0.09 -0.32 -0.35 -0.32 -0.39 -0.48 -0.55 -0.52 0.37 0.36 0.29 0.35 0.38 0.43 0.41 0.41 0.48

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.0 0.5 0.3 0.9 1.3 -0.1 -0.4 -1.3 -2.3 3.9 7.0 7.8 0 4.1 2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -2.1 0 0 0 0 0 0 0 0 3.6 1.8 1.9 1.9 1.1 1.5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.3 0 0 0 0 0 0 0 0 -13.2 -17.9 -17.2 -5.5 -7.0 -8.2
Nucleus 3.0 4.1 2.6 1.5 3.0 2.4 0.8 1.8 3.4 1.7 1.2 2.1 0 0 0
Nuclear Periphery -2.7 0 0 0 0 0 0 0 0 -3.2 -2.4 -6.0 1.3 -1.5 0.8
Nucleolus -1.2 0 0 0 0 0 0 0 0 -3.9 -5.4 -5.3 3.7 -0.6 1.1
Peroxisomes 0 0 0 0 0 0 0 0 0 2.5 0 2.2 0 0 0
SpindlePole 0.1 0 0 0 0 0 0 0 0 0.9 0.8 1.4 0 -1.2 -1.2
Vacuole -1.8 0.8 -4.1 -2.9 -3.6 -3.9 -2.7 -3.6 -2.2 4.8 7.0 7.0 4.1 7.0 5.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.1791 3.0889 2.9053 2.5575 3.0297 2.5496 2.2441 1.891 1.8784 1.5414 1.7881 1.7851 1.0812 1.6779 1.09 1.5295 1.5572 1.4556
Actin 0.093 0.0013 0.0072 0.0183 0.0267 0.0023 0.0127 0.0008 0.0082 0.0117 0.0025 0.0016 0.0278 0.0074 0.0091 0.0081 0.0008 0.0067
Bud 0.0007 0.0002 0.0002 0.0002 0.0001 0.0001 0.0003 0.0001 0.0002 0.0006 0.0002 0 0.0003 0.0002 0.0004 0.0003 0.0001 0.0003
Bud Neck 0.0021 0.0027 0.0008 0.0012 0.0005 0.0008 0.0021 0.0003 0.0008 0.0015 0.0009 0.0008 0.0005 0.0011 0.0006 0.0003 0.0002 0.0004
Bud Periphery 0.0011 0.0003 0.0004 0.0008 0.0002 0.0004 0.0006 0.0002 0.0006 0.0013 0.0007 0.0001 0.0004 0.001 0.0006 0.001 0.0003 0.0004
Bud Site 0.003 0.0191 0.0022 0.0007 0.0001 0.0002 0.0033 0.0003 0.0007 0.0037 0.0018 0.0001 0.0025 0.001 0.0087 0.0013 0.0002 0.0002
Cell Periphery 0.0003 0.0004 0.0002 0.0002 0.0001 0.0003 0.0002 0.0001 0.0001 0.0005 0.0002 0 0.0002 0.0003 0.0002 0.0002 0.0001 0
Cytoplasm 0.0254 0.0212 0.0066 0.0096 0.0068 0.0021 0.003 0.0028 0.003 0.0009 0.0007 0.0008 0.0042 0.0014 0.003 0.0062 0.0005 0.003
Cytoplasmic Foci 0.0214 0.006 0.0054 0.0056 0.0064 0.0033 0.0058 0.0008 0.0048 0.0076 0.0039 0.0007 0.0346 0.0031 0.016 0.0079 0.0032 0.0064
Eisosomes 0.0009 0.0001 0.0008 0.0003 0.0019 0.0001 0.0001 0 0.0001 0.0001 0.0001 0 0.0002 0.0003 0.0002 0.0003 0.0001 0
Endoplasmic Reticulum 0.0121 0.017 0.0058 0.0187 0.0028 0.0063 0.005 0.0024 0.0048 0.0038 0.0017 0.0014 0.0058 0.0072 0.0037 0.007 0.0035 0.0029
Endosome 0.0392 0.0152 0.0097 0.0117 0.0078 0.0114 0.0172 0.0033 0.0063 0.0197 0.0117 0.0052 0.0524 0.0103 0.0133 0.0218 0.0571 0.017
Golgi 0.0135 0.0024 0.0028 0.0043 0.0047 0.0021 0.0055 0.0009 0.0021 0.009 0.004 0.0011 0.0194 0.0059 0.0097 0.0043 0.0186 0.0079
Lipid Particles 0.0319 0.051 0.0466 0.0437 0.0625 0.0473 0.0467 0.0145 0.0137 0.0238 0.0415 0.0085 0.1239 0.0497 0.0427 0.0365 0.1625 0.0276
Mitochondria 0.0072 0.0016 0.0068 0.0058 0.0024 0.0046 0.0071 0.0012 0.0072 0.0228 0.0094 0.0014 0.0034 0.0102 0.0083 0.0104 0.0065 0.0019
None 0.0502 0.0292 0.0625 0.0093 0.2028 0.0042 0.0019 0.001 0.0019 0.0017 0.0014 0.0046 0.0054 0.0043 0.0034 0.0038 0.0007 0.0007
Nuclear Periphery 0.5409 0.6702 0.6789 0.7501 0.5914 0.7857 0.7895 0.7823 0.8042 0.7156 0.7643 0.8467 0.6573 0.8135 0.7707 0.8127 0.6752 0.8553
Nucleolus 0.0056 0.0229 0.011 0.0039 0.0043 0.0208 0.0129 0.0262 0.0141 0.0287 0.0274 0.021 0.0039 0.012 0.0093 0.0042 0.0141 0.0092
Nucleus 0.0576 0.0747 0.0478 0.0451 0.0064 0.0511 0.0375 0.1007 0.0722 0.0515 0.0596 0.058 0.0034 0.0283 0.0237 0.011 0.0132 0.0144
Peroxisomes 0.006 0.0019 0.0028 0.0063 0.0069 0.0032 0.007 0.0004 0.0045 0.0095 0.004 0.0003 0.0171 0.0013 0.0059 0.0021 0.0019 0.004
Punctate Nuclear 0.0681 0.0396 0.082 0.0365 0.0505 0.0362 0.0259 0.0493 0.0352 0.0557 0.0475 0.0399 0.0237 0.0148 0.0492 0.0271 0.0173 0.0308
Vacuole 0.0037 0.0055 0.0022 0.0026 0.0013 0.0056 0.0029 0.001 0.0021 0.01 0.0034 0.0011 0.0023 0.0024 0.0018 0.0022 0.005 0.0014
Vacuole Periphery 0.0161 0.0173 0.0174 0.0253 0.0133 0.0117 0.0127 0.0113 0.0134 0.0201 0.0127 0.0066 0.0114 0.0244 0.0195 0.0314 0.0188 0.0093

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.6625 4.3262 5.8854 9.6015 7.3204 8.0614 12.9404 10.8251 9.7602 10.549
Translational Efficiency 0.7232 1.3244 0.9356 0.5987 0.8002 0.5581 0.4166 0.569 0.703 0.7255

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1679 251 2184 1290 1725 1898 1231 99 3404 2149 3415 1389

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 720.13 891.16 860.42 884.08 745.10 793.02 941.54 1029.94 732.78 804.48 889.66 894.48
Standard Deviation 93.23 109.15 111.96 124.15 90.45 97.21 123.54 131.53 92.68 103.59 122.62 130.21
Intensity Change Log 2 — 0.307427 0.256784 0.295920 — 0.089923 0.337588 0.467054 — 0.200919 0.298440 0.385479

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000186 0.000125 0.000350 0.000753 0.000106 0.000161 0.000281 0.000078 0.000146 0.000157 0.000325 0.000705
Bud Neck 0.000325 0.000467 0.002284 0.002774 0.000114 0.000359 0.000930 0.001327 0.000218 0.000371 0.001796 0.002671
Bud Site 0.000459 0.000201 0.001328 0.002572 0.000048 0.001009 0.000195 0.004917 0.000251 0.000915 0.000920 0.002739
Cell Periphery 0.000057 0.000017 0.000132 0.000049 0.000033 0.000039 0.000016 0.000012 0.000045 0.000037 0.000090 0.000046
Cytoplasm 0.007881 0.000793 0.021729 0.004496 0.002782 0.005355 0.001464 0.002015 0.005297 0.004822 0.014424 0.004320
Cytoplasmic Foci 0.008469 0.001096 0.003190 0.002829 0.002202 0.005451 0.000143 0.003353 0.005293 0.004943 0.002092 0.002866
Eisosomes 0.000015 0.000004 0.000029 0.000011 0.000010 0.000015 0.000008 0.000006 0.000012 0.000013 0.000021 0.000010
Endoplasmic Reticulum 0.005483 0.003899 0.004288 0.008409 0.003670 0.003822 0.003638 0.003963 0.004564 0.003831 0.004054 0.008092
Endosome 0.008240 0.003671 0.002227 0.006397 0.002614 0.006789 0.000682 0.008087 0.005389 0.006425 0.001670 0.006517
Golgi 0.004594 0.000960 0.000346 0.002497 0.001006 0.003227 0.000134 0.000889 0.002776 0.002963 0.000270 0.002382
Lipid Particles 0.132019 0.027493 0.004060 0.003976 0.070763 0.065232 0.001114 0.002255 0.100977 0.060824 0.002998 0.003853
Mitochondria 0.008649 0.001007 0.004078 0.004389 0.003658 0.007924 0.001191 0.000838 0.006120 0.007116 0.003037 0.004136
Mitotic Spindle 0.020984 0.047017 0.065195 0.161311 0.011872 0.030811 0.086164 0.305580 0.016367 0.032704 0.072754 0.171594
None 0.005570 0.001037 0.011325 0.000444 0.002895 0.002783 0.000474 0.000056 0.004214 0.002579 0.007413 0.000416
Nuclear Periphery 0.054169 0.069309 0.145720 0.176814 0.069572 0.071444 0.181945 0.176662 0.061975 0.071195 0.158778 0.176803
Nuclear Periphery Foci 0.715334 0.827031 0.393076 0.575047 0.806153 0.746728 0.637129 0.459134 0.761357 0.756107 0.481049 0.566786
Nucleolus 0.013797 0.005681 0.091161 0.007837 0.011246 0.021500 0.037970 0.001352 0.012504 0.019653 0.071987 0.007374
Nucleus 0.009873 0.008331 0.245804 0.020674 0.009221 0.023237 0.044312 0.004242 0.009542 0.021496 0.173173 0.019502
Peroxisomes 0.001275 0.000158 0.000641 0.000489 0.000657 0.001051 0.000198 0.000574 0.000962 0.000947 0.000481 0.000495
Vacuole 0.001583 0.000994 0.002386 0.014133 0.000858 0.001697 0.001358 0.019684 0.001216 0.001615 0.002015 0.014528
Vacuole Periphery 0.001039 0.000707 0.000650 0.004101 0.000519 0.001365 0.000654 0.004977 0.000775 0.001288 0.000651 0.004163

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.42 -3.82 -1.93 -2.17 -1.34 -2.37 -6.53 0.11 1.71 5.17 -0.23 -7.31 -2.07 -2.05 -1.37
Bud Neck -0.68 -9.46 -7.19 -6.32 -2.09 -5.03 -4.16 -3.00 -2.47 -0.85 -3.19 -10.44 -7.65 -7.21 -3.10
Bud Site 1.11 -2.05 -3.75 -4.19 -2.01 -1.72 -1.93 -1.63 -1.36 -1.56 -1.30 -2.56 -4.44 -2.96 -3.05
Cell Periphery 8.92 -2.61 0.75 -5.06 2.77 -1.33 3.35 3.30 5.77 0.73 1.84 -2.47 -0.58 -1.72 2.16
Cytoplasm 5.95 -7.12 1.51 -5.07 8.90 -2.47 1.42 -0.24 1.17 -0.90 0.46 -7.56 -0.28 -0.66 6.63
Cytoplasmic Foci 6.87 4.02 5.17 -2.99 1.54 -4.56 5.25 -0.49 1.24 -1.67 0.65 4.30 3.69 3.12 -0.44
Eisosomes 7.58 -8.23 1.83 -4.87 9.29 -4.36 0.96 1.05 2.88 0.69 -1.45 -8.37 0.56 1.60 7.12
Endoplasmic Reticulum 2.26 1.97 -3.30 -4.69 -4.60 -0.42 -0.74 -0.47 -0.33 -0.20 2.06 0.93 -4.34 -5.14 -4.76
Endosome 3.68 6.65 1.59 -2.65 -6.28 -4.70 5.89 -1.43 -0.30 -1.94 -1.13 7.52 -1.69 -0.34 -7.53
Golgi 3.83 6.80 2.41 -1.38 -2.76 -3.63 2.97 0.26 3.05 -1.23 -0.23 7.24 0.73 0.83 -2.94
Lipid Particles 14.16 24.03 24.13 4.47 0.84 1.12 18.79 18.28 18.55 -1.71 8.98 29.88 29.48 18.50 -0.82
Mitochondria 7.74 4.45 3.10 -3.40 -0.18 -3.94 6.14 5.28 6.52 1.11 -0.96 5.49 1.89 2.32 -1.07
Mitotic Spindle -3.05 -11.48 -18.41 -10.51 -11.24 -6.32 -12.75 -8.19 -7.68 -6.18 -6.02 -17.44 -20.68 -17.88 -12.19
None 4.12 -4.29 6.13 0.61 9.91 -0.14 3.25 3.59 5.47 1.63 2.18 -3.77 6.73 5.12 9.81
Nuclear Periphery -2.47 -19.01 -21.02 -13.08 -5.65 -0.37 -19.27 -4.82 -4.76 0.39 -3.07 -25.86 -20.73 -18.24 -3.50
Nuclear Periphery Foci -7.56 32.61 13.45 16.99 -16.08 7.11 17.60 10.69 8.80 5.54 1.08 38.70 21.37 18.96 -8.05
Nucleolus 3.16 -22.78 2.87 -1.34 25.24 -5.34 -9.37 7.03 10.46 13.30 -4.35 -24.71 3.13 6.42 26.20
Nucleus 0.46 -35.15 -5.42 -4.28 30.79 -6.12 -11.17 1.08 5.41 10.15 -6.02 -34.71 -5.63 -0.72 28.22
Peroxisomes 4.81 2.39 2.80 -2.24 1.02 -2.38 5.77 0.39 1.68 -1.18 0.22 3.19 2.33 2.01 0.05
Vacuole 0.86 -2.04 -8.09 -8.12 -7.53 -1.71 -1.77 -2.06 -1.97 -1.90 -0.97 -2.97 -8.51 -8.27 -7.76
Vacuole Periphery 0.64 2.35 -4.27 -4.00 -4.93 -2.89 -0.34 -1.47 -1.17 -1.40 -2.05 0.72 -4.89 -4.01 -5.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Nuclear pore-associated protein; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; contains a PAM domain implicated in protein-protein binding
Localization
Cell Percentages nuclear periphery (81%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Thp1

Thp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Thp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available