Standard name
Human Ortholog
Description Putative RNA exonuclease; possibly involved in pre-rRNA processing and ribosome assembly
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.06 0 0 0.06 0.06 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0.06 0 0 0 0.06 0.08 0.11 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0 0.08 0.05 0.1 0.11 0.08 0.07 0 0.1 0.11 0.16 0.19 0.06 0.06 0.07 0 0 0 0 0 0.05
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.05 0.05 0.06 0 0.1 0.09 0.06 0 0 0 0 0.08 0.07 0.15 0 0 0 0 0.07 0.07 0.07 0.16 0.16
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0.24 0 0.06 0.31 0.21 0.19 0.2 0.54 0.35 0.56 0.55 0 0 0 0.09 0.07 0 0 0 0 0 0 0.05
Nucleus 0.42 0.31 0.23 0.21 0.33 0.16 0.15 0.11 0.12 0.15 0.16 0.14 0.1 0.15 0.16 0.18 0.21 0.24 0.21 0.17 0.1 0.15 0.1 0.09
Nuclear Periphery 0.05 0.09 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0
Nucleolus 0.53 0.56 0.64 0.69 0.39 0.3 0.24 0.23 0.25 0.25 0.25 0.24 0.75 0.63 0.59 0.75 0.73 0.68 0.56 0.48 0.4 0.42 0.32 0.3
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0.16 0.43 0.48 0.3 0.55 0.53 0.5 0.35 0.5 0.33 0.33 0.54 0.46 0.41 0.16 0.19 0.19 0.05 0.14 0.29 0.17 0.19 0.2
Vac/Vac Membrane 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 2 0 1 12 9 10 21 26 15 11 23 0 2 1 1 0 1 1 7 0 1 6 4
Bud Neck 0 2 3 2 4 3 14 18 6 11 9 14 9 6 0 1 0 1 0 3 2 1 4 5
Bud Site 2 8 0 4 12 9 11 14 23 28 33 22 0 1 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 4 6 13 10 17 18 45 42 35 23 13 34 22 37 61 21 14 21 0 1 0 4 6 15
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 8 0 0 2 0 2 1
Endosome 1 25 12 14 2 33 38 24 10 5 11 8 17 17 48 16 10 13 7 42 18 11 49 49
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 1 0 0 0 3 3
Mitochondria 15 131 5 13 67 69 84 75 224 118 167 192 2 1 2 33 17 12 1 16 4 4 9 14
Nucleus 82 168 58 49 71 55 67 43 52 52 49 50 20 35 52 64 51 70 49 99 29 24 29 27
Nuclear Periphery 10 49 5 0 0 3 0 0 1 1 1 1 0 0 0 6 3 3 22 22 8 3 5 6
Nucleolus 104 305 163 160 84 101 107 87 102 84 73 84 154 149 195 273 180 198 135 283 115 67 99 92
Peroxisomes 0 1 0 0 0 2 3 3 7 0 1 1 0 0 5 4 3 0 0 1 1 0 3 2
SpindlePole 4 89 108 111 64 185 234 188 147 170 99 115 110 110 136 58 46 55 11 80 83 26 58 61
Vac/Vac Membrane 11 15 4 0 3 11 11 15 9 7 5 5 1 0 4 10 2 8 9 23 10 9 18 16
Unique Cell Count 197 543 253 231 215 336 438 374 416 342 297 349 204 238 328 363 245 290 241 586 286 159 308 315
Labelled Cell Count 233 801 371 364 337 498 624 531 643 514 472 549 335 358 505 491 329 391 241 586 286 159 308 315


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 5.4 7.4 6.4 4.5 4.7 4.7 4.8 3.7 4.2 3.9 3.9 7.2 6.3 5.9 9.3 11.7 10.6 7.4 7.8 7.8
Std Deviation (1e-4) 1.4 1.0 2.0 1.6 1.2 1.1 1.4 1.0 0.9 1.1 1.0 0.8 1.7 1.8 1.7 3.0 3.1 3.5 1.8 1.6 1.8
Intensity Change (Log2) – – – -0.21 -0.72 -0.66 -0.65 -0.64 -0.99 -0.81 -0.93 -0.94 -0.05 -0.23 -0.34 0.32 0.65 0.51 0.0 0.06 0.07

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 2.1 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 1.2 0.1 2.3 2.6 1.6 0.8 -0.4 2.1 2.3 3.8 4.8 0.3 0.3 1.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.6 0 0 0 0 0 0 0 0 1.6 1.1 3.9 -0.2 -0.4 -0.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.1 0 0 0 0 0 0 0 0 0 0 0 3.6 2.7 1.4
Nucleus -0.5 2.4 -2.0 -2.5 -3.8 -3.5 -2.4 -1.9 -2.7 -3.7 -2.3 -2.2 -1.6 -0.6 0.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.1 0 0 0 0 0 0 0 0 2.6 -0.4 -1.2 2.9 2.2 0.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1.2 0 0 0 0 0 0 0 0 2.4 0.8 -0.3 -7.4 -5.8 -6.0
Vacuole 0 0 1.3 0.8 1.7 0 0 0 0 0 0 0 1.0 0 0.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.7341 5.2377 4.7379 4.4268 4.703 4.7569 7.3622 6.8992 8.042 6.6405 7.1673 8.0419 5.6169 5.8687 5.1484 5.0766 5.4835 5.6314
Actin 0.0209 0.0001 0.0011 0.0004 0.0002 0.0019 0.0981 0.029 0 0.0211 0.0002 0.0001 0.009 0 0.0039 0.044 0.0015 0.0001
Bud 0.0004 0.0001 0.0002 0.0002 0.0001 0.0002 0.0009 0.0003 0.0001 0.0003 0.0003 0.0001 0.0003 0.0003 0.0001 0.0004 0.0003 0
Bud Neck 0.0025 0.0011 0.0012 0.0014 0.0008 0.0023 0.0022 0.0026 0.0008 0.0039 0.0017 0.0019 0.0018 0.0008 0.0009 0.0025 0.0015 0.0011
Bud Periphery 0.0008 0.0002 0.0003 0.001 0.0005 0.001 0.0032 0.0006 0.0001 0.0006 0.0013 0.0002 0.0007 0.0005 0.0001 0.0009 0.0014 0.0002
Bud Site 0.0041 0.0009 0.0015 0.001 0.0003 0.0007 0.0055 0.0425 0.001 0.0039 0.0003 0.0004 0.0022 0.0021 0.0005 0.0042 0.0011 0.0003
Cell Periphery 0.0005 0.0005 0.0005 0.0008 0.0003 0.0006 0.0004 0.0007 0.0004 0.001 0.0003 0.0003 0.0006 0.0003 0.0002 0.0006 0.0006 0.0002
Cytoplasm 0.0019 0.0003 0.0016 0.0001 0.0001 0.0001 0.0048 0.0018 0.0012 0.0002 0.0003 0 0.0039 0.0001 0.0002 0.0012 0.0034 0.0001
Cytoplasmic Foci 0.0296 0.0051 0.017 0.0031 0.0007 0.0044 0.0176 0.0069 0.017 0.0175 0.0302 0.0071 0.0225 0.0028 0.0058 0.0027 0.0071 0.0023
Eisosomes 0.0006 0 0.0001 0.0001 0.0001 0.0001 0.0009 0.0003 0 0.0001 0 0 0.0003 0 0.0001 0.0003 0.0001 0
Endoplasmic Reticulum 0.0013 0.0002 0.0078 0.0003 0.0002 0.0005 0.0045 0.0003 0.0001 0.0002 0.0006 0 0.0032 0.0001 0.0002 0.0038 0.0047 0.0003
Endosome 0.0129 0.0028 0.0082 0.0055 0.0008 0.0033 0.0425 0.0025 0.0119 0.0124 0.007 0.0017 0.0072 0.0006 0.0035 0.0035 0.0311 0.0019
Golgi 0.006 0.001 0.0082 0.0025 0.0007 0.0049 0.0087 0.0048 0.0008 0.0256 0.0018 0.0015 0.0035 0.0005 0.0014 0.0015 0.0078 0.0007
Lipid Particles 0.0868 0.0342 0.0462 0.047 0.0248 0.0245 0.0363 0.0329 0.0324 0.0745 0.106 0.0652 0.0325 0.0161 0.0297 0.0308 0.0484 0.0256
Mitochondria 0.0053 0.0004 0.0034 0.0249 0.0026 0.0138 0.0175 0.0055 0.0005 0.0035 0.0006 0.0007 0.0045 0.0002 0.0031 0.0062 0.0293 0.0016
None 0.0181 0.0002 0.0011 0.0002 0.0004 0.0002 0.0136 0.0007 0.0025 0.0003 0.0007 0.0001 0.0109 0.0001 0.0003 0.0012 0.001 0.0002
Nuclear Periphery 0.0216 0.0225 0.0131 0.0237 0.1088 0.0318 0.06 0.0197 0.0007 0.0043 0.058 0.0021 0.0226 0.0193 0.0079 0.0294 0.1141 0.0454
Nucleolus 0.5822 0.7355 0.7355 0.7552 0.6171 0.7273 0.5192 0.6601 0.8061 0.6433 0.6553 0.8168 0.7188 0.8004 0.7906 0.6206 0.4397 0.6824
Nucleus 0.0978 0.121 0.0984 0.0705 0.1596 0.1135 0.0336 0.0908 0.057 0.06 0.0811 0.0615 0.0886 0.1164 0.0916 0.1191 0.2023 0.1088
Peroxisomes 0.0159 0.0005 0.0066 0.0012 0.0004 0.0015 0.0095 0.0182 0.0011 0.0138 0.0012 0.0023 0.0055 0.0005 0.0007 0.0015 0.0021 0.0004
Punctate Nuclear 0.0852 0.0623 0.0365 0.0481 0.0769 0.0616 0.1116 0.0783 0.0592 0.1069 0.0411 0.0353 0.056 0.037 0.0576 0.1193 0.087 0.1255
Vacuole 0.0036 0.0076 0.0098 0.0077 0.0013 0.0029 0.0028 0.0006 0.0065 0.0054 0.0051 0.0018 0.0039 0.0013 0.0012 0.0031 0.0081 0.0014
Vacuole Periphery 0.0021 0.0034 0.0017 0.005 0.0035 0.003 0.0066 0.0009 0.0006 0.0013 0.0069 0.0009 0.0015 0.0006 0.0003 0.0033 0.0073 0.0015

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 41.8533 35.1467 17.6674 16.4649 24.6657 10.1406 19.4879 11.2188 11.3083 22.3187
Translational Efficiency 1.6361 1.4821 2.0783 1.5732 1.8294 3.699 1.4872 1.9464 1.4175 1.7736

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
148 1549 272 1945 1711 1752 1630 2850 1859 3301 1902 4795

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 697.23 858.22 1049.33 1160.77 782.87 945.78 1079.76 1273.78 776.05 904.69 1075.41 1227.94
Standard Deviation 97.96 159.75 126.74 202.98 115.39 124.42 166.60 258.40 116.43 148.66 161.85 243.88
Intensity Change Log 2 — 0.299713 0.589762 0.735376 — 0.272732 0.463866 0.702271 — 0.285505 0.524542 0.717960

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000320 0.000643 0.000578 0.001082 0.000225 0.000317 0.000295 0.000495 0.000233 0.000470 0.000336 0.000733
Bud Neck 0.006423 0.010564 0.007919 0.019181 0.002628 0.005068 0.006660 0.022386 0.002930 0.007647 0.006840 0.021086
Bud Site 0.002466 0.002608 0.000963 0.004060 0.000346 0.000738 0.000370 0.003178 0.000515 0.001616 0.000455 0.003536
Cell Periphery 0.000155 0.000164 0.000028 0.000136 0.000058 0.000070 0.000019 0.000160 0.000066 0.000114 0.000021 0.000150
Cytoplasm 0.008924 0.003327 0.000100 0.003327 0.000864 0.001007 0.000172 0.002765 0.001505 0.002095 0.000162 0.002993
Cytoplasmic Foci 0.009407 0.002945 0.000378 0.002406 0.000824 0.001884 0.000111 0.001106 0.001508 0.002382 0.000149 0.001633
Eisosomes 0.000166 0.000079 0.000053 0.000082 0.000059 0.000073 0.000046 0.000112 0.000067 0.000076 0.000047 0.000100
Endoplasmic Reticulum 0.004151 0.004883 0.001940 0.001229 0.002171 0.002982 0.000803 0.001407 0.002328 0.003874 0.000966 0.001335
Endosome 0.005378 0.004985 0.000435 0.002313 0.001503 0.004554 0.000420 0.001794 0.001811 0.004756 0.000422 0.002005
Golgi 0.004115 0.002231 0.000502 0.002004 0.000813 0.001737 0.000173 0.000813 0.001076 0.001969 0.000221 0.001296
Lipid Particles 0.006240 0.002351 0.000186 0.000495 0.000986 0.001323 0.000118 0.000956 0.001405 0.001806 0.000128 0.000769
Mitochondria 0.006100 0.005539 0.001198 0.005981 0.002636 0.004824 0.000924 0.004013 0.002912 0.005160 0.000963 0.004812
Mitotic Spindle 0.045895 0.015002 0.033437 0.043857 0.014007 0.012829 0.003412 0.024209 0.016546 0.013849 0.007706 0.032179
None 0.006926 0.006277 0.000456 0.001446 0.002778 0.002343 0.000296 0.001386 0.003108 0.004189 0.000319 0.001410
Nuclear Periphery 0.002217 0.010381 0.002820 0.014405 0.006081 0.006727 0.002972 0.013764 0.005774 0.008441 0.002950 0.014024
Nuclear Periphery Foci 0.178895 0.055037 0.009010 0.012607 0.068474 0.038174 0.001758 0.011279 0.077265 0.046087 0.002795 0.011818
Nucleolus 0.481234 0.459846 0.593399 0.566678 0.563117 0.502837 0.521140 0.517806 0.556598 0.482663 0.531474 0.537630
Nucleus 0.207859 0.402255 0.338544 0.295711 0.329457 0.402669 0.456415 0.368389 0.319776 0.402475 0.439559 0.338908
Peroxisomes 0.017019 0.004286 0.005710 0.004819 0.002103 0.003210 0.001190 0.002462 0.003290 0.003715 0.001836 0.003418
Vacuole 0.002992 0.003830 0.001472 0.008273 0.000423 0.003503 0.000713 0.007372 0.000628 0.003657 0.000821 0.007738
Vacuole Periphery 0.003118 0.002768 0.000871 0.009906 0.000446 0.003131 0.001991 0.014150 0.000659 0.002961 0.001831 0.012428

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.51 -4.44 -2.48 -1.46 -1.33 -3.72 -3.47 -12.06 -7.06 -9.54 -9.69 -5.58 -4.14 -2.18 -3.18
Bud Neck -2.72 -1.48 -10.73 -10.85 -12.55 -6.11 -9.35 -24.49 -21.19 -18.74 -10.06 -9.88 -31.30 -22.05 -23.58
Bud Site 0.00 1.23 -2.72 -3.70 -5.89 -3.92 -0.43 -8.88 -7.43 -8.81 -4.44 -0.03 -10.98 -6.69 -11.17
Cell Periphery 0.01 3.21 0.41 0.77 -7.41 -1.24 4.54 -5.88 -5.43 -9.23 -3.99 5.30 -6.43 -2.91 -12.20
Cytoplasm 1.10 1.88 0.86 -0.89 -5.06 -0.67 2.56 -3.60 -3.30 -4.88 -1.35 3.03 -3.56 -2.58 -6.96
Cytoplasmic Foci 2.78 3.57 2.75 -0.16 -4.10 -2.61 3.47 -1.08 1.94 -5.40 -1.50 4.75 -0.51 1.17 -6.86
Eisosomes 7.03 8.37 6.87 -0.26 -4.44 -4.94 6.23 -9.43 -6.23 -12.41 -2.83 8.76 -7.31 -5.55 -14.37
Endoplasmic Reticulum -1.21 4.04 6.62 12.78 3.53 -4.33 10.86 6.09 10.16 -7.87 -8.16 10.54 8.16 16.11 -4.90
Endosome 0.43 5.09 3.13 3.57 -5.32 -3.88 3.33 -1.00 3.51 -4.66 -5.24 4.58 -0.68 5.08 -6.12
Golgi 2.89 4.99 3.19 0.62 -2.77 -2.18 5.64 0.11 2.26 -6.78 -2.66 7.01 -0.39 2.16 -5.52
Lipid Particles 3.25 5.35 5.08 2.87 -1.05 -1.13 3.85 0.21 0.92 -1.81 -0.93 5.65 2.08 2.63 -2.16
Mitochondria 0.14 2.26 -0.14 -0.62 -8.81 -2.64 3.39 -2.81 0.91 -12.81 -3.23 3.91 -3.81 0.33 -14.79
Mitotic Spindle 2.74 0.56 -0.05 -8.69 -1.02 0.37 5.22 -4.84 -5.59 -10.69 1.15 3.32 -7.28 -10.03 -11.88
None 0.09 2.02 1.66 5.24 -4.02 0.65 4.11 2.09 2.35 -7.08 -1.47 4.55 2.54 5.76 -8.10
Nuclear Periphery -7.46 -1.06 -8.60 -1.97 -7.60 -0.66 3.95 -6.23 -5.31 -9.40 -3.12 3.93 -7.93 -5.02 -11.84
Nuclear Periphery Foci 5.93 8.09 8.01 11.31 -0.91 6.47 17.69 14.81 9.49 -9.78 7.03 18.98 16.59 14.78 -10.55
Nucleolus 0.73 -4.15 -3.23 -10.36 2.21 7.77 5.18 7.12 -1.09 1.08 11.04 3.51 4.48 -7.79 0.26
Nucleus -11.69 -6.73 -5.82 13.11 2.85 -9.43 -15.77 -5.66 4.61 11.56 -12.81 -15.93 -3.44 11.54 14.96
Peroxisomes 3.79 3.13 3.61 -1.56 1.70 -2.88 4.04 -1.31 2.30 -8.72 -0.34 3.62 0.08 0.67 -7.51
Vacuole -0.66 0.56 -3.63 -5.07 -7.64 -4.16 -2.21 -12.82 -4.78 -12.10 -6.21 -1.63 -15.11 -6.99 -14.69
Vacuole Periphery 0.03 0.91 -2.93 -7.61 -10.05 -4.21 -5.18 -16.27 -10.36 -13.56 -5.76 -3.93 -18.47 -13.11 -15.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative RNA exonuclease; possibly involved in pre-rRNA processing and ribosome assembly
Localization
Cell Percentages nucleolus (47%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-1

Rex4

Rex4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rex4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available