Standard name
Human Ortholog
Description Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway; delivers cargo proteins aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p) to the phagophore assembly site for packaging into Cvt vesicles; interaction with Atg19p during the Cvt pathway requires phosphorylation by Hrr25p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.05 0 0.09 0.05 0.07 0.11 0.14 0.12 0.12 0.19 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0.08 0.06 0.07 0.05 0.09 0.06 0 0.06 0.06 0.07 0 0.06 0.11 0.05 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0.05 0.06 0.06 0.06 0.07 0 0.05 0 0 0 0 0.06 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.73 0.75 0.8 0.88 0.57 0.48 0.4 0.35 0.29 0.34 0.26 0.39 0.75 0.73 0.77 0.35 0.37 0.36 0.49 0.57 0.5 0.61 0.58 0.61
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.08 0.05 0 0.05 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.15 0 0 0.11 0.06 0.12 0.24 0.23 0.27 0.3 0.36 0.36 0 0 0 0.06 0 0 0.11 0.07 0.2 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.06 0 0 0 0.06 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0.07 0.07 0 0 0 0.06 0 0 0 0 0 0 0.05 0 0 0 0 0 0
SpindlePole 0.17 0.16 0.11 0.08 0.36 0.39 0.42 0.48 0.45 0.38 0.38 0.32 0.23 0.24 0.2 0.58 0.56 0.54 0.2 0.25 0.13 0.22 0.24 0.23
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 1 0 1 0 2 0 0 0 0 1 0 0 0 0 0 2 1 5 1 0 2
Bud 6 3 6 1 13 7 16 21 21 22 15 25 4 3 3 15 11 8 4 5 2 3 7 2
Bud Neck 7 8 5 1 12 8 15 9 13 11 4 8 20 19 8 17 26 11 1 4 0 1 1 5
Bud Site 7 4 1 0 3 7 13 11 9 13 3 7 2 0 0 4 15 8 – – – – – –
Cell Periphery 1 4 0 1 0 0 0 0 0 0 0 1 0 0 0 0 2 2 0 0 0 0 1 0
Cytoplasm 153 165 105 121 82 70 86 69 44 65 32 53 233 191 222 104 92 77 111 136 66 90 119 153
Endoplasmic Reticulum 1 0 0 0 0 1 0 0 0 0 0 0 0 0 1 9 6 10 4 1 0 0 0 1
Endosome 0 12 3 3 6 6 2 8 3 2 5 1 1 4 4 19 8 17 11 7 6 5 7 7
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 1 1 1 1 0 0 0 1
Mitochondria 32 4 5 15 9 18 52 45 41 57 45 49 1 0 0 17 11 6 25 15 26 2 7 7
Nucleus 2 0 0 0 0 0 6 0 0 2 1 1 0 0 0 4 0 0 0 0 0 0 0 0
Nuclear Periphery 1 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 3 0 2 0 2 8 5 6 3 12 2 6 1 3 0 14 7 9 1 0 1 0 0 0
Peroxisomes 0 4 3 5 4 10 15 7 4 8 8 6 0 0 0 7 4 10 1 0 0 0 0 0
SpindlePole 35 35 15 11 52 57 91 95 68 72 47 43 71 64 58 169 138 115 45 59 17 31 48 58
Vac/Vac Membrane 0 1 4 0 2 0 2 2 3 1 2 1 0 0 0 4 4 1 6 2 0 1 4 8
Unique Cell Count 209 219 131 138 144 145 215 197 152 190 125 135 310 262 287 293 246 213 227 238 133 147 206 253
Labelled Cell Count 249 243 149 159 185 193 304 275 209 265 164 201 336 284 296 384 325 275 227 238 133 147 206 253


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 2.9 3.9 5.3 3.7 3.9 4.2 3.7 3.6 3.8 3.4 3.2 3.0 5.0 5.1 5.0 6.0 5.4 5.7 5.1 5.5 5.6
Std Deviation (1e-4) 0.7 0.8 3.9 1.9 1.6 3.3 2.4 1.8 2.2 1.8 1.5 0.8 0.9 1.0 1.1 2.3 1.5 2.0 1.2 1.4 1.6
Intensity Change (Log2) – – – -0.52 -0.43 -0.34 -0.49 -0.55 -0.47 -0.65 -0.7 -0.8 -0.07 -0.04 -0.08 0.19 0.03 0.12 -0.04 0.06 0.08

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.647 -0.3593 -0.5925 -0.9749 -0.2091 -0.531 -0.3507 -0.2888 -0.4743 -0.5676 -0.3423 -0.2344 -0.9386 -1.0375 -1.3248 -1.346 -0.9356 -1.0816
Actin 0.0258 0.0033 0.0029 0.0001 0.0312 0.0011 0.0213 0.0017 0.014 0.0333 0.0012 0.0218 0.0184 0.0034 0.0006 0.0001 0.0371 0.0216
Bud 0.0002 0.0037 0.0026 0.0054 0.0019 0.0003 0.0004 0.0027 0.001 0.0008 0.0004 0.0005 0.0122 0.0121 0.0037 0 0.0004 0.0001
Bud Neck 0.0008 0.001 0.001 0.0009 0.0005 0.0026 0.0007 0.0009 0.0007 0.0006 0.0023 0.0011 0.0073 0.0014 0.0003 0.0041 0.0189 0.0003
Bud Periphery 0.0006 0.0044 0.0048 0.0102 0.007 0.0005 0.0006 0.0021 0.001 0.0014 0.0004 0.0006 0.0081 0.0059 0.0024 0 0.0006 0.0002
Bud Site 0.0007 0.0062 0.0046 0.0011 0.0032 0.001 0.0018 0.0073 0.0088 0.0038 0.0047 0.0005 0.0035 0.0259 0.0032 0.0001 0.0009 0.0002
Cell Periphery 0.0001 0.0002 0.0005 0.0002 0.0001 0.0001 0.0003 0.0002 0.0002 0.0001 0.0001 0 0.0007 0.0014 0.0002 0.0001 0.0002 0
Cytoplasm 0.0143 0.0335 0.0208 0.0407 0.0194 0.0263 0.0301 0.0401 0.0287 0.0093 0.0559 0.062 0.0374 0.0568 0.0523 0.0106 0.0535 0.0946
Cytoplasmic Foci 0.3001 0.2906 0.2925 0.2263 0.2836 0.3297 0.2287 0.1465 0.1493 0.4575 0.2089 0.2379 0.2084 0.1977 0.1484 0.2814 0.3234 0.2561
Eisosomes 0.0004 0.0004 0.0002 0 0.0004 0.0001 0.0001 0.0002 0.0002 0.0002 0.0001 0.0001 0.0005 0.0002 0.0002 0.0001 0.0002 0.0003
Endoplasmic Reticulum 0.0007 0.0003 0.0007 0.0006 0.0016 0.0004 0.002 0.0009 0.0008 0.0005 0.001 0.0015 0.0011 0.0008 0.0014 0.0001 0.0032 0.0006
Endosome 0.0139 0.023 0.012 0.0049 0.013 0.0155 0.0273 0.0194 0.0157 0.0477 0.036 0.0092 0.0378 0.0129 0.0285 0.0057 0.0376 0.0308
Golgi 0.0034 0.0022 0.0024 0.001 0.0048 0.0014 0.0049 0.0023 0.0025 0.0117 0.0023 0.0016 0.006 0.0013 0.0012 0.0009 0.0059 0.0067
Lipid Particles 0.0327 0.0354 0.0335 0.0096 0.0188 0.025 0.0231 0.0268 0.0195 0.0514 0.0088 0.0164 0.0576 0.0172 0.0224 0.0165 0.0368 0.0154
Mitochondria 0.001 0.0011 0.0023 0.0013 0.0074 0.0009 0.0018 0.0011 0.0016 0.0045 0.0005 0.0007 0.0116 0.0039 0.0012 0.0001 0.001 0.0087
None 0.5421 0.4948 0.5457 0.6097 0.5392 0.5363 0.5778 0.6982 0.673 0.255 0.5667 0.5662 0.515 0.6123 0.6821 0.6487 0.449 0.5069
Nuclear Periphery 0.001 0.0003 0.0008 0.0002 0.0069 0.0006 0.0127 0.0009 0.0042 0.0003 0.0008 0.0024 0.0061 0.0011 0.0045 0 0.0036 0.0003
Nucleolus 0.0053 0.0079 0.0014 0.0004 0.0005 0.0015 0.0017 0.0043 0.0061 0.0015 0.0019 0.0006 0.0034 0.0071 0.0015 0.0002 0.0003 0.0002
Nucleus 0.0014 0.0015 0.001 0.0006 0.0021 0.0011 0.0085 0.0024 0.01 0.0004 0.0034 0.0043 0.0115 0.002 0.0057 0.0002 0.0015 0.0003
Peroxisomes 0.0354 0.0249 0.0419 0.0693 0.04 0.0268 0.025 0.0139 0.0192 0.1096 0.065 0.0212 0.0227 0.0067 0.0088 0.0278 0.0173 0.0238
Punctate Nuclear 0.0196 0.0632 0.026 0.0164 0.0164 0.0257 0.0203 0.0231 0.0404 0.0081 0.0374 0.0501 0.0251 0.0226 0.029 0.0031 0.0069 0.0321
Vacuole 0.0005 0.0019 0.0019 0.001 0.001 0.0025 0.0091 0.0044 0.0026 0.002 0.0019 0.0009 0.0044 0.0062 0.002 0.0001 0.001 0.0008
Vacuole Periphery 0.0001 0.0002 0.0003 0.0001 0.001 0.0005 0.0017 0.0005 0.0003 0.0004 0.0002 0.0002 0.0013 0.0012 0.0004 0 0.0005 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 27.4083 22.9206 22.2864 32.4877 32.0971 28.2768 31.5659 33.7103 43.0762 34.5018
Translational Efficiency 0.6259 0.7683 0.7398 0.7324 0.5686 1.1852 0.8443 0.7704 0.7967 0.7146

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
924 530 1491 1511 193 1891 684 599 1117 2421 2175 2110

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 621.46 705.31 730.93 759.10 708.72 663.49 837.00 802.46 636.54 672.65 764.29 771.41
Standard Deviation 67.22 74.94 90.07 115.67 80.87 74.43 93.74 104.36 77.18 76.53 103.68 114.26
Intensity Change Log 2 — 0.182596 0.234072 0.288628 — -0.095141 0.240012 0.179214 — 0.041290 0.237240 0.231367

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000227 0.000383 0.000195 0.000640 0.000209 0.000421 0.000841 0.001808 0.000224 0.000412 0.000399 0.000971
Bud Neck 0.055723 0.055677 0.025852 0.033743 0.057205 0.050274 0.018493 0.023771 0.055979 0.051457 0.023538 0.030912
Bud Site 0.037881 0.035264 0.018125 0.058490 0.036414 0.023400 0.050279 0.097887 0.037627 0.025997 0.028237 0.069675
Cell Periphery 0.000299 0.000251 0.000378 0.000500 0.000315 0.000168 0.000237 0.000206 0.000302 0.000186 0.000334 0.000416
Cytoplasm 0.191287 0.185929 0.287085 0.324343 0.176373 0.317975 0.232300 0.263034 0.188710 0.289068 0.269856 0.306938
Cytoplasmic Foci 0.432536 0.399013 0.044519 0.081874 0.452738 0.332894 0.078079 0.124855 0.436027 0.347369 0.055073 0.094075
Eisosomes 0.000187 0.000164 0.000076 0.000121 0.000181 0.000158 0.000093 0.000105 0.000186 0.000159 0.000082 0.000116
Endoplasmic Reticulum 0.000324 0.000504 0.000806 0.001680 0.000288 0.000354 0.002330 0.001954 0.000318 0.000387 0.001285 0.001758
Endosome 0.066498 0.065433 0.008521 0.024426 0.054841 0.038748 0.016187 0.022682 0.064483 0.044590 0.010931 0.023931
Golgi 0.013801 0.016226 0.000578 0.005646 0.013731 0.008157 0.000956 0.004493 0.013789 0.009923 0.000697 0.005319
Lipid Particles 0.016661 0.008786 0.001928 0.005247 0.007737 0.008080 0.003899 0.002659 0.015119 0.008235 0.002548 0.004512
Mitochondria 0.009544 0.018543 0.001374 0.006726 0.001687 0.014286 0.001074 0.010863 0.008187 0.015218 0.001279 0.007900
Mitotic Spindle 0.004200 0.014232 0.010034 0.039610 0.010905 0.008653 0.022031 0.052578 0.005359 0.009874 0.013807 0.043292
None 0.004858 0.002532 0.016164 0.005970 0.004626 0.003038 0.004932 0.007706 0.004818 0.002927 0.012632 0.006463
Nuclear Periphery 0.000257 0.000236 0.001212 0.001279 0.000200 0.000284 0.001466 0.000928 0.000247 0.000273 0.001292 0.001179
Nuclear Periphery Foci 0.007178 0.005521 0.001758 0.002207 0.025175 0.000844 0.003511 0.004124 0.010287 0.001868 0.002309 0.002751
Nucleolus 0.008809 0.003237 0.008708 0.006086 0.008875 0.004194 0.006084 0.002562 0.008820 0.003985 0.007883 0.005086
Nucleus 0.041682 0.055301 0.541703 0.287389 0.040162 0.088086 0.486609 0.166094 0.041420 0.080909 0.524377 0.252955
Peroxisomes 0.080629 0.091732 0.009987 0.018625 0.090891 0.054426 0.023071 0.095093 0.082402 0.062593 0.014102 0.040333
Vacuole 0.026278 0.038910 0.020593 0.092202 0.016653 0.043983 0.047271 0.113537 0.024615 0.042872 0.028983 0.098259
Vacuole Periphery 0.001142 0.002125 0.000403 0.003197 0.000794 0.001576 0.000257 0.003061 0.001082 0.001696 0.000357 0.003159

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.40 -1.14 -5.62 -2.95 -3.10 -2.58 -4.48 -7.00 -5.58 -2.15 -2.90 -3.69 -8.70 -5.38 -3.53
Bud Neck 0.01 4.31 4.92 3.93 0.78 0.18 2.27 2.56 6.97 0.84 0.59 5.14 5.77 7.45 1.00
Bud Site 0.48 3.78 -3.16 -3.30 -6.98 1.89 -2.39 -4.91 -8.01 -2.95 3.50 1.29 -5.36 -9.55 -6.99
Cell Periphery 0.92 -0.51 -0.64 -1.36 -0.13 2.45 1.41 2.18 -0.90 1.94 3.99 0.24 0.34 -3.43 0.11
Cytoplasm 0.28 -6.84 -9.01 -8.00 -2.37 -7.79 -1.46 -3.12 7.17 -2.74 -11.18 -6.11 -9.06 2.42 -3.62
Cytoplasmic Foci 2.37 37.73 34.88 26.87 -4.54 5.73 17.09 16.87 28.64 -0.55 9.20 41.02 38.80 42.68 -3.92
Eisosomes 1.14 6.60 4.53 3.38 -5.35 0.79 1.58 1.56 2.53 -0.04 1.84 6.20 4.66 5.30 -4.06
Endoplasmic Reticulum -1.63 -10.42 -14.01 -10.90 -5.88 -0.35 -12.63 -12.13 -12.25 0.44 -1.11 -15.92 -18.22 -17.89 -3.86
Endosome 0.20 12.36 9.59 7.85 -5.13 1.84 4.07 4.35 6.65 0.64 4.55 12.64 10.70 9.24 -3.92
Golgi -0.87 10.93 7.18 5.58 -3.19 2.87 6.93 6.17 7.38 -1.96 3.17 12.43 8.94 7.46 -3.54
Lipid Particles 4.14 8.59 6.90 3.46 -4.16 -0.23 2.29 3.55 7.64 2.74 4.72 8.55 7.50 6.24 -2.75
Mitochondria -2.30 5.53 3.09 3.89 -2.72 -10.00 1.53 -1.32 4.34 -1.62 -4.13 5.63 2.65 7.30 -3.15
Mitotic Spindle -3.21 -5.89 -11.75 -8.20 -7.29 0.67 -3.98 -4.69 -6.55 -1.07 -2.35 -7.90 -13.00 -12.00 -6.46
None 2.37 -4.80 0.25 -2.59 5.29 1.20 -0.11 0.20 -1.26 0.43 2.23 -4.49 0.30 -2.55 5.17
Nuclear Periphery 0.44 -20.34 -16.49 -16.53 -5.66 -2.60 -16.79 -13.79 -13.17 1.16 -1.15 -25.88 -20.16 -19.93 -4.52
Nuclear Periphery Foci 0.55 3.14 3.12 1.49 -0.32 3.75 2.66 2.98 -4.24 1.27 5.24 3.76 4.16 -3.00 0.75
Nucleolus 3.25 -3.15 0.28 -3.60 3.85 2.36 0.39 2.12 -0.72 3.95 3.65 -2.53 1.60 -3.03 5.32
Nucleus -2.57 -49.29 -27.79 -23.06 21.70 -6.45 -25.54 -13.35 -10.80 12.99 -10.29 -55.08 -30.79 -24.76 24.91
Peroxisomes -1.32 13.74 12.44 10.71 -2.72 3.62 6.45 3.30 0.20 -4.12 4.03 14.76 11.37 10.16 -4.69
Vacuole -3.61 -1.59 -22.02 -18.71 -21.64 -7.19 -10.03 -17.88 -15.85 -11.63 -7.79 -7.47 -27.88 -24.69 -23.61
Vacuole Periphery -2.78 5.73 -1.72 0.52 -3.66 -3.52 2.91 -0.83 0.47 -1.63 -3.46 6.57 -1.77 0.05 -3.98
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway; delivers cargo proteins aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p) to the phagophore assembly site for packaging into Cvt vesicles; interaction with Atg19p during the Cvt pathway requires phosphorylation by Hrr25p
Localization
Cell Percentages spindle pole (17%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Atg19

Atg19


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Atg19-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available