Standard name
Human Ortholog
Description Subunit of the COP9 signalosome (CSN) complex; this complex cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.96 0.98 0.94 0.91 0.79 0.79 0.78 0.7 0.72 0.67 0.68 0.97 0.94 0.98 0.87 0.94 0.92 0.92 0.88 0.85 0.77 0.81 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0.1 0.44 0.39 0.33 0.44 0.4 0.51 0.4 0 0 0 0 0.05 0 0 0 0.05 0.1 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.07 0 0 0 0 0.08 0.08 0 0.07 0 0 0 0.09 0 0 0 0 0 0.06 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 3 5 1 5 2
Bud 0 0 1 0 2 10 7 16 14 6 17 14 0 0 0 0 0 0 0 3 6 1 6 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 3 0 2 1
Bud Site 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 4 1 0 3 1 2 3 1 1 2 7 1 0 0 3 0 1 0 0 1 0 2 2
Cytoplasm 112 352 548 275 507 626 766 826 458 527 424 502 94 201 201 88 90 97 118 410 475 117 316 291
Endoplasmic Reticulum 0 0 1 0 0 0 1 0 0 2 0 3 2 3 2 1 1 2 0 6 5 1 2 0
Endosome 0 0 1 1 7 3 4 19 8 7 2 10 0 2 0 0 0 0 0 2 3 2 3 2
Golgi 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 5 2 2 1 0
Mitochondria 3 7 11 19 56 348 377 351 291 291 326 297 2 0 0 3 5 2 0 13 30 14 24 12
Nucleus 0 1 1 0 1 8 10 11 9 5 5 8 1 0 0 4 4 5 0 1 0 0 0 0
Nuclear Periphery 0 6 0 0 0 0 2 6 2 3 2 3 0 1 0 0 0 0 0 1 0 0 0 0
Nucleolus 0 0 1 0 1 3 2 6 1 1 1 2 0 0 0 0 0 0 0 0 1 0 0 0
Peroxisomes 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1
SpindlePole 0 0 0 0 0 0 6 6 5 4 2 3 0 0 0 0 0 1 1 1 5 0 4 5
Vac/Vac Membrane 1 2 9 19 23 20 28 45 51 58 26 51 0 9 4 9 4 4 2 7 5 8 12 20
Unique Cell Count 116 368 559 292 559 794 969 1061 655 735 634 738 97 213 205 101 96 105 128 467 559 153 392 345
Labelled Cell Count 116 374 576 314 601 1019 1205 1290 844 905 807 900 100 217 207 109 104 115 128 467 559 153 392 345


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.3 4.3 4.1 4.2 4.1 3.2 3.6 4.0 3.7 3.9 3.6 3.8 4.8 5.4 5.3 5.7 5.9 5.7 5.0 5.0 5.3
Std Deviation (1e-4) 0.5 0.8 1.0 1.4 1.3 1.1 1.4 1.2 1.0 1.0 0.9 1.1 0.8 1.4 1.1 0.9 0.8 0.7 1.2 1.0 1.5
Intensity Change (Log2) – – – 0.02 -0.01 -0.35 -0.18 -0.02 -0.17 -0.07 -0.18 -0.12 0.22 0.39 0.37 0.48 0.52 0.47 0.27 0.27 0.38

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.8786 0.0459 -0.1883 -0.4428 -0.918 -0.1685 0.3854 0.9686 0.6962 0.3196 0.2173 0.831 -0.9482 -0.5304 -0.6968 -0.4862 -0.4578 -0.8003
Actin 0.0004 0.0009 0.001 0.001 0.0023 0.0006 0.0123 0.0008 0.0035 0.0015 0.005 0.0027 0.0384 0.0011 0.025 0.0611 0.0004 0.0002
Bud 0.0027 0.0051 0.0058 0.0003 0.0047 0.0022 0.0129 0.0247 0.025 0.0166 0.0155 0.0149 0.0005 0.0032 0.0013 0.0006 0 0
Bud Neck 0.0001 0.0001 0.0002 0.0027 0.0004 0.0005 0.0042 0.0009 0.0019 0.0013 0.0017 0.0079 0.0031 0 0.0015 0.0012 0.0001 0.0002
Bud Periphery 0.0014 0.0009 0.0025 0.0002 0.0017 0.0011 0.0081 0.0059 0.0103 0.0072 0.0058 0.008 0.0006 0.005 0.0042 0.0006 0 0
Bud Site 0.001 0.0022 0.0028 0.0109 0.0012 0.0002 0.0252 0.0482 0.025 0.0081 0.0057 0.0021 0.0032 0.0036 0.0024 0.0172 0 0
Cell Periphery 0.0002 0.0002 0.0003 0.0001 0.0002 0.0001 0.0007 0.0009 0.0006 0.0004 0.0002 0.0003 0.0002 0.0001 0.0014 0.0007 0 0
Cytoplasm 0.093 0.2222 0.1052 0.21 0.1225 0.2022 0.1252 0.1455 0.1209 0.1162 0.173 0.2074 0.1484 0.1757 0.1598 0.2806 0.1787 0.2361
Cytoplasmic Foci 0.0164 0.0054 0.0126 0.0466 0.0513 0.015 0.0359 0.0075 0.0133 0.017 0.0142 0.0155 0.0241 0.0037 0.0105 0.0523 0.0035 0.0027
Eisosomes 0.0004 0.0004 0.0002 0.0002 0.0001 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001 0.0004 0.0001 0.0003 0.0004 0.0001 0.0001
Endoplasmic Reticulum 0.0021 0.0018 0.0013 0.0011 0.0008 0.001 0.0021 0.0009 0.0011 0.0016 0.0013 0.002 0.0012 0.0011 0.0016 0.009 0.0034 0.0007
Endosome 0.002 0.0009 0.0013 0.0046 0.002 0.0011 0.007 0.0011 0.0036 0.0019 0.0017 0.0031 0.0136 0.0009 0.0038 0.0083 0.0023 0.0006
Golgi 0.0001 0.0001 0.0001 0.0008 0.0012 0.0001 0.0022 0.0001 0.0011 0.0005 0.0007 0.0006 0.0042 0.0003 0.0042 0.0052 0.0001 0
Lipid Particles 0.0007 0.0003 0.0005 0.0023 0.0012 0.0004 0.0078 0.0002 0.0021 0.0005 0.0013 0.001 0.0182 0.0002 0.0125 0.0022 0.0005 0.0001
Mitochondria 0.0046 0.0005 0.0025 0.0006 0.0036 0.0013 0.0053 0.0008 0.0044 0.0019 0.0013 0.0069 0.0148 0.0011 0.0211 0.0011 0.1657 0.0001
None 0.8641 0.7518 0.85 0.6795 0.7526 0.7486 0.6837 0.6954 0.701 0.6503 0.6855 0.6067 0.692 0.8014 0.7415 0.5445 0.6395 0.757
Nuclear Periphery 0.0017 0.0008 0.001 0.0021 0.0015 0.0008 0.0033 0.0026 0.0033 0.0077 0.0041 0.0054 0.0013 0.0003 0.0005 0.0015 0.0014 0.0002
Nucleolus 0.001 0.0004 0.0022 0.0006 0.0011 0.0011 0.004 0.0022 0.0033 0.0058 0.0026 0.0027 0.0012 0 0.0002 0.0001 0 0
Nucleus 0.0033 0.0038 0.0036 0.0019 0.004 0.0065 0.0133 0.0268 0.0321 0.054 0.0263 0.0366 0.0166 0.0012 0.0006 0.0017 0.0024 0.0014
Peroxisomes 0.0005 0.0002 0.0004 0.0175 0.0158 0.0013 0.0109 0.0003 0.0077 0.0021 0.0032 0.0028 0.013 0.0004 0.0057 0.0007 0.0002 0
Punctate Nuclear 0.0017 0.0015 0.0054 0.0163 0.0308 0.015 0.0329 0.0339 0.038 0.103 0.0496 0.0712 0.0036 0.0002 0.0005 0.0101 0.0008 0.0002
Vacuole 0.002 0.0006 0.0009 0.0006 0.0005 0.0005 0.0022 0.0012 0.0014 0.0019 0.0011 0.0016 0.0013 0.0004 0.0012 0.0007 0.0006 0.0002
Vacuole Periphery 0.0005 0.0001 0.0002 0.0002 0.0003 0.0002 0.0005 0.0001 0.0003 0.0005 0.0003 0.0005 0.0004 0.0001 0.0001 0.0002 0.0002 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.2701 7.1255 4.9098 7.0077 3.6909 9.1046 7.8479 7.2939 11.1502 7.1436
Translational Efficiency 0.5102 0.5449 0.7942 0.588 0.626 0.3628 0.6022 0.5826 0.5006 0.5318

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2160 578 2455 1060 1611 1747 2710 83 3771 2325 5165 1143

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 657.18 634.21 765.50 832.70 626.09 695.11 747.93 825.08 643.90 679.97 756.28 832.15
Standard Deviation 76.16 88.23 82.58 92.73 83.09 100.62 84.29 203.25 80.68 101.17 83.95 104.77
Intensity Change Log 2 — -0.051328 0.220114 0.341508 — 0.150871 0.256533 0.398164 — 0.050864 0.237997 0.369428

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000031 0.000429 0.000083 0.000179 0.000046 0.000494 0.000043 0.000813 0.000037 0.000478 0.000062 0.000225
Bud Neck 0.007077 0.021710 0.005906 0.002857 0.009384 0.017048 0.009896 0.038753 0.008062 0.018207 0.007999 0.005464
Bud Site 0.003007 0.017428 0.011378 0.004132 0.001560 0.020420 0.010050 0.157589 0.002389 0.019676 0.010681 0.015275
Cell Periphery 0.000104 0.000176 0.000112 0.000081 0.000098 0.000420 0.000071 0.000731 0.000102 0.000359 0.000090 0.000129
Cytoplasm 0.527625 0.496882 0.546555 0.371928 0.488846 0.525712 0.563765 0.393663 0.511058 0.518545 0.555585 0.373506
Cytoplasmic Foci 0.099589 0.151130 0.012204 0.007154 0.162296 0.152360 0.007683 0.075452 0.126378 0.152054 0.009832 0.012113
Eisosomes 0.000063 0.000132 0.000018 0.000017 0.000095 0.000139 0.000011 0.000080 0.000077 0.000137 0.000014 0.000021
Endoplasmic Reticulum 0.000437 0.000357 0.000519 0.001637 0.000543 0.000618 0.000384 0.004467 0.000482 0.000553 0.000448 0.001843
Endosome 0.002912 0.013776 0.001039 0.001270 0.005658 0.006763 0.000619 0.034696 0.004085 0.008506 0.000819 0.003698
Golgi 0.000364 0.004207 0.000067 0.000428 0.000784 0.001848 0.000075 0.001017 0.000543 0.002434 0.000071 0.000471
Lipid Particles 0.004515 0.006410 0.000391 0.000611 0.007770 0.003873 0.000240 0.005304 0.005906 0.004504 0.000312 0.000952
Mitochondria 0.003869 0.011266 0.000485 0.000713 0.004487 0.003261 0.000375 0.000725 0.004133 0.005251 0.000427 0.000714
Mitotic Spindle 0.002834 0.007277 0.005883 0.001986 0.002858 0.005219 0.002233 0.000714 0.002845 0.005730 0.003968 0.001894
None 0.004268 0.005341 0.005545 0.003571 0.004874 0.004071 0.005657 0.005629 0.004527 0.004387 0.005604 0.003721
Nuclear Periphery 0.000685 0.000534 0.000648 0.001685 0.000840 0.000376 0.000662 0.000544 0.000751 0.000415 0.000656 0.001602
Nuclear Periphery Foci 0.000242 0.000604 0.000184 0.000550 0.000355 0.000197 0.000127 0.004765 0.000290 0.000298 0.000154 0.000856
Nucleolus 0.000999 0.002974 0.000445 0.000409 0.001230 0.000972 0.000351 0.000912 0.001098 0.001470 0.000396 0.000446
Nucleus 0.320929 0.159049 0.388997 0.580374 0.271487 0.195573 0.383818 0.067428 0.299807 0.186493 0.386280 0.543125
Peroxisomes 0.001612 0.025085 0.000138 0.000121 0.003653 0.004909 0.000136 0.005164 0.002483 0.009925 0.000137 0.000487
Vacuole 0.018268 0.074628 0.019170 0.019720 0.032558 0.054728 0.013600 0.198557 0.024373 0.059676 0.016247 0.032707
Vacuole Periphery 0.000570 0.000605 0.000233 0.000575 0.000579 0.001000 0.000203 0.002997 0.000574 0.000902 0.000217 0.000751

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.52 -4.99 -2.60 1.71 -1.63 -1.63 -0.36 -3.55 -1.19 -3.54 -2.09 -4.64 -3.43 1.04 -2.92
Bud Neck -4.27 0.92 4.82 5.71 3.35 -5.21 0.18 -2.73 -1.90 -2.75 -7.65 0.42 2.74 8.79 2.18
Bud Site -3.94 -5.20 -0.70 3.59 4.18 -8.37 -6.49 -5.58 -4.80 -5.28 -8.82 -7.76 -4.91 1.87 -1.65
Cell Periphery -2.87 -0.19 2.04 3.99 1.98 -5.12 4.42 -1.84 -0.78 -1.92 -5.32 1.96 -0.99 4.33 -1.56
Cytoplasm 2.65 -0.11 17.42 9.07 17.33 -3.75 -6.87 3.62 4.74 5.52 -0.54 -4.75 16.98 15.96 20.30
Cytoplasmic Foci -6.49 28.26 30.10 20.03 5.12 1.77 33.14 7.87 7.02 -6.18 -5.49 43.03 39.73 37.16 -1.39
Eisosomes -5.68 15.16 13.63 9.59 -0.48 -4.20 17.89 1.06 3.91 -6.50 -7.56 23.63 17.24 14.75 -4.84
Endoplasmic Reticulum 0.53 -3.33 -8.72 -8.71 -7.80 -0.30 1.17 -2.57 -2.52 -2.61 -0.45 -1.73 -8.36 -6.50 -8.10
Endosome -4.80 6.79 4.85 5.52 -1.28 -1.49 11.48 -4.26 -4.08 -5.08 -5.89 13.46 0.77 5.38 -5.10
Golgi -3.40 7.27 -0.00 3.25 -0.95 -2.82 4.48 -0.67 2.34 -4.96 -4.89 6.56 0.45 4.16 -1.15
Lipid Particles -1.00 12.62 11.32 3.51 -3.61 5.06 10.65 0.81 -1.05 -2.78 2.65 15.68 12.15 6.61 -4.46
Mitochondria -2.26 3.96 3.63 3.53 -1.35 0.94 3.82 3.50 3.45 -2.19 -0.79 5.52 4.97 4.85 -1.86
Mitotic Spindle -1.61 -2.79 -0.51 1.24 2.04 -1.64 0.37 0.28 1.60 0.06 -2.32 -1.93 -0.51 1.50 0.91
None -0.50 -1.85 1.76 0.98 3.72 0.85 -0.83 -0.11 -0.39 0.12 0.24 -1.94 1.99 1.08 4.24
Nuclear Periphery 1.31 -1.18 -13.02 -12.20 -13.76 3.05 0.18 0.23 -1.68 0.16 4.35 -0.45 -10.65 -16.85 -13.16
Nuclear Periphery Foci -1.43 -0.11 -3.44 -0.62 -3.73 1.80 2.04 -3.31 -3.41 -3.42 -0.01 1.30 -4.55 -4.54 -5.21
Nucleolus -1.35 5.56 4.86 1.75 0.29 1.22 6.06 1.49 0.40 -2.94 -1.01 8.45 5.71 2.69 -0.45
Nucleus 16.97 -10.75 -26.06 -35.67 -17.59 10.11 -15.63 14.50 9.32 23.83 20.25 -18.07 -25.12 -36.08 -15.33
Peroxisomes -5.78 7.03 7.10 6.19 0.49 -1.24 6.60 -0.58 0.09 -3.14 -6.29 9.06 7.25 8.42 -2.81
Vacuole -11.05 -4.08 -4.47 8.75 -1.89 -7.59 4.23 -7.18 -6.29 -7.51 -14.97 0.37 -5.53 5.06 -5.65
Vacuole Periphery 0.02 2.43 0.20 0.20 -0.91 -1.58 4.77 -3.00 -2.29 -3.56 -1.49 4.16 -0.30 0.64 -1.59
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the COP9 signalosome (CSN) complex; this complex cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response
Localization
Cell Percentages cytoplasm (24%), nucleus (2%), mixed (49%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rri2

Rri2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rri2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available